Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID	57326
Gene name	PBX homeobox interacting protein 1
Gene symbol	PBXIP1
Synonyms (NCBI Gene)	HPIP
Chromosome	1
Chromosome location	1q21.3
Summary	The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can

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Show/Hide all (320)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017972	hsa-miR-335-5p	Microarray	18185580
MIRT019795	hsa-miR-375	Microarray	20215506
MIRT020198	hsa-miR-130b-3p	Sequencing	20371350
MIRT026000	hsa-miR-148a-3p	Sequencing	20371350
MIRT028003	hsa-miR-93-5p	Sequencing	20371350
MIRT029484	hsa-miR-26b-5p	Microarray	19088304
MIRT050995	hsa-miR-17-5p	CLASH	23622248
MIRT050607	hsa-miR-20a-5p	CLASH	23622248
MIRT038457	hsa-miR-296-3p	CLASH	23622248
MIRT026000	hsa-miR-148a-3p	Luciferase reporter assay	23321675
MIRT026000	hsa-miR-148a-3p	Luciferase reporter assay	23321675
MIRT440035	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT440035	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT1216172	hsa-miR-103b	CLIP-seq
MIRT1216173	hsa-miR-106a	CLIP-seq
MIRT1216174	hsa-miR-106b	CLIP-seq
MIRT1216175	hsa-miR-1245b-5p	CLIP-seq
MIRT1216176	hsa-miR-138	CLIP-seq
MIRT1216177	hsa-miR-142-5p	CLIP-seq
MIRT1216178	hsa-miR-148a	CLIP-seq
MIRT1216179	hsa-miR-148b	CLIP-seq
MIRT1216180	hsa-miR-152	CLIP-seq
MIRT1216181	hsa-miR-153	CLIP-seq
MIRT1216182	hsa-miR-17	CLIP-seq
MIRT1216183	hsa-miR-1909	CLIP-seq
MIRT1216184	hsa-miR-1915	CLIP-seq
MIRT1216185	hsa-miR-20a	CLIP-seq
MIRT1216186	hsa-miR-20b	CLIP-seq
MIRT1216187	hsa-miR-2115	CLIP-seq
MIRT1216188	hsa-miR-22	CLIP-seq
MIRT1216189	hsa-miR-3142	CLIP-seq
MIRT1216190	hsa-miR-3200-5p	CLIP-seq
MIRT1216191	hsa-miR-3609	CLIP-seq
MIRT1216192	hsa-miR-3618	CLIP-seq
MIRT1216193	hsa-miR-3913-3p	CLIP-seq
MIRT1216194	hsa-miR-412	CLIP-seq
MIRT1216195	hsa-miR-4267	CLIP-seq
MIRT1216196	hsa-miR-4299	CLIP-seq
MIRT1216197	hsa-miR-4318	CLIP-seq
MIRT1216198	hsa-miR-4434	CLIP-seq
MIRT1216199	hsa-miR-4446-3p	CLIP-seq
MIRT1216200	hsa-miR-448	CLIP-seq
MIRT1216201	hsa-miR-4492	CLIP-seq
MIRT1216202	hsa-miR-4498	CLIP-seq
MIRT1216203	hsa-miR-450b-3p	CLIP-seq
MIRT1216204	hsa-miR-4516	CLIP-seq
MIRT1216205	hsa-miR-4640-3p	CLIP-seq
MIRT1216206	hsa-miR-4652-5p	CLIP-seq
MIRT1216207	hsa-miR-4682	CLIP-seq
MIRT1216208	hsa-miR-4693-5p	CLIP-seq
MIRT1216209	hsa-miR-4713-3p	CLIP-seq
MIRT1216210	hsa-miR-4753-5p	CLIP-seq
MIRT1216211	hsa-miR-4772-3p	CLIP-seq
MIRT1216212	hsa-miR-4796-3p	CLIP-seq
MIRT1216213	hsa-miR-483-5p	CLIP-seq
MIRT1216214	hsa-miR-489	CLIP-seq
MIRT1216215	hsa-miR-495	CLIP-seq
MIRT1216216	hsa-miR-496	CLIP-seq
MIRT1216217	hsa-miR-516a-3p	CLIP-seq
MIRT1216218	hsa-miR-519d	CLIP-seq
MIRT1216219	hsa-miR-548ah	CLIP-seq
MIRT1216220	hsa-miR-555	CLIP-seq
MIRT1216221	hsa-miR-586	CLIP-seq
MIRT1216222	hsa-miR-627	CLIP-seq
MIRT1216223	hsa-miR-638	CLIP-seq
MIRT1216224	hsa-miR-762	CLIP-seq
MIRT1216225	hsa-miR-769-3p	CLIP-seq
MIRT1216226	hsa-miR-892a	CLIP-seq
MIRT1216227	hsa-miR-924	CLIP-seq
MIRT1216228	hsa-miR-93	CLIP-seq
MIRT1216172	hsa-miR-103b	CLIP-seq
MIRT2062427	hsa-miR-1197	CLIP-seq
MIRT2062428	hsa-miR-1321	CLIP-seq
MIRT2062429	hsa-miR-139-5p	CLIP-seq
MIRT2062430	hsa-miR-150	CLIP-seq
MIRT1216188	hsa-miR-22	CLIP-seq
MIRT2062431	hsa-miR-23a	CLIP-seq
MIRT2062432	hsa-miR-23b	CLIP-seq
MIRT2062433	hsa-miR-23c	CLIP-seq
MIRT2062434	hsa-miR-27a	CLIP-seq
MIRT2062435	hsa-miR-27b	CLIP-seq
MIRT2062436	hsa-miR-2861	CLIP-seq
MIRT2062437	hsa-miR-299-3p	CLIP-seq
MIRT2062438	hsa-miR-3127-3p	CLIP-seq
MIRT2062439	hsa-miR-3162-5p	CLIP-seq
MIRT2062440	hsa-miR-3183	CLIP-seq
MIRT1216190	hsa-miR-3200-5p	CLIP-seq
MIRT1216192	hsa-miR-3618	CLIP-seq
MIRT2062441	hsa-miR-3689d	CLIP-seq
MIRT2062442	hsa-miR-4268	CLIP-seq
MIRT2062443	hsa-miR-4310	CLIP-seq
MIRT1216203	hsa-miR-450b-3p	CLIP-seq
MIRT1216206	hsa-miR-4652-5p	CLIP-seq
MIRT1216207	hsa-miR-4682	CLIP-seq
MIRT1216209	hsa-miR-4713-3p	CLIP-seq
MIRT2062444	hsa-miR-4713-5p	CLIP-seq
MIRT2062445	hsa-miR-4723-3p	CLIP-seq
MIRT2062446	hsa-miR-4731-5p	CLIP-seq
MIRT2062447	hsa-miR-4739	CLIP-seq
MIRT2062448	hsa-miR-4756-5p	CLIP-seq
MIRT1216211	hsa-miR-4772-3p	CLIP-seq
MIRT2062449	hsa-miR-4786-3p	CLIP-seq
MIRT2062450	hsa-miR-513a-5p	CLIP-seq
MIRT2062451	hsa-miR-532-3p	CLIP-seq
MIRT1216220	hsa-miR-555	CLIP-seq
MIRT2062452	hsa-miR-582-5p	CLIP-seq
MIRT1216222	hsa-miR-627	CLIP-seq
MIRT1216223	hsa-miR-638	CLIP-seq
MIRT1216225	hsa-miR-769-3p	CLIP-seq
MIRT1216227	hsa-miR-924	CLIP-seq
MIRT1216172	hsa-miR-103b	CLIP-seq
MIRT1216173	hsa-miR-106a	CLIP-seq
MIRT1216174	hsa-miR-106b	CLIP-seq
MIRT2062427	hsa-miR-1197	CLIP-seq
MIRT2290821	hsa-miR-1207-5p	CLIP-seq
MIRT2290822	hsa-miR-1224-5p	CLIP-seq
MIRT1216175	hsa-miR-1245b-5p	CLIP-seq
MIRT2290823	hsa-miR-1254	CLIP-seq
MIRT2290824	hsa-miR-128	CLIP-seq
MIRT2062428	hsa-miR-1321	CLIP-seq
MIRT1216176	hsa-miR-138	CLIP-seq
MIRT2062429	hsa-miR-139-5p	CLIP-seq
MIRT1216177	hsa-miR-142-5p	CLIP-seq
MIRT1216178	hsa-miR-148a	CLIP-seq
MIRT1216179	hsa-miR-148b	CLIP-seq
MIRT2062430	hsa-miR-150	CLIP-seq
MIRT1216180	hsa-miR-152	CLIP-seq
MIRT1216181	hsa-miR-153	CLIP-seq
MIRT1216182	hsa-miR-17	CLIP-seq
MIRT2290825	hsa-miR-1825	CLIP-seq
MIRT1216183	hsa-miR-1909	CLIP-seq
MIRT1216184	hsa-miR-1915	CLIP-seq
MIRT1216185	hsa-miR-20a	CLIP-seq
MIRT1216186	hsa-miR-20b	CLIP-seq
MIRT1216188	hsa-miR-22	CLIP-seq
MIRT2290826	hsa-miR-221	CLIP-seq
MIRT2290827	hsa-miR-222	CLIP-seq
MIRT2290828	hsa-miR-2355-5p	CLIP-seq
MIRT2062431	hsa-miR-23a	CLIP-seq
MIRT2062432	hsa-miR-23b	CLIP-seq
MIRT2062433	hsa-miR-23c	CLIP-seq
MIRT2062434	hsa-miR-27a	CLIP-seq
MIRT2062435	hsa-miR-27b	CLIP-seq
MIRT2062436	hsa-miR-2861	CLIP-seq
MIRT2290829	hsa-miR-3116	CLIP-seq
MIRT2062438	hsa-miR-3127-3p	CLIP-seq
MIRT1216189	hsa-miR-3142	CLIP-seq
MIRT2290830	hsa-miR-3151	CLIP-seq
MIRT2290831	hsa-miR-3155	CLIP-seq
MIRT2290832	hsa-miR-3155b	CLIP-seq
MIRT2062439	hsa-miR-3162-5p	CLIP-seq
MIRT2062440	hsa-miR-3183	CLIP-seq
MIRT1216190	hsa-miR-3200-5p	CLIP-seq
MIRT2290833	hsa-miR-3202	CLIP-seq
MIRT2290834	hsa-miR-331-3p	CLIP-seq
MIRT2290835	hsa-miR-342-5p	CLIP-seq
MIRT1216191	hsa-miR-3609	CLIP-seq
MIRT1216192	hsa-miR-3618	CLIP-seq
MIRT2290836	hsa-miR-3657	CLIP-seq
MIRT2062441	hsa-miR-3689d	CLIP-seq
MIRT2290837	hsa-miR-3714	CLIP-seq
MIRT1216193	hsa-miR-3913-3p	CLIP-seq
MIRT2290838	hsa-miR-3918	CLIP-seq
MIRT2290839	hsa-miR-4254	CLIP-seq
MIRT1216195	hsa-miR-4267	CLIP-seq
MIRT2062442	hsa-miR-4268	CLIP-seq
MIRT2290840	hsa-miR-4297	CLIP-seq
MIRT1216196	hsa-miR-4299	CLIP-seq
MIRT1216197	hsa-miR-4318	CLIP-seq
MIRT2290841	hsa-miR-4428	CLIP-seq
MIRT2290842	hsa-miR-4433	CLIP-seq
MIRT1216198	hsa-miR-4434	CLIP-seq
MIRT2290843	hsa-miR-4436a	CLIP-seq
MIRT2290844	hsa-miR-4438	CLIP-seq
MIRT1216199	hsa-miR-4446-3p	CLIP-seq
MIRT2290845	hsa-miR-4447	CLIP-seq
MIRT2290846	hsa-miR-4455	CLIP-seq
MIRT2290847	hsa-miR-4472	CLIP-seq
MIRT1216200	hsa-miR-448	CLIP-seq
MIRT1216201	hsa-miR-4492	CLIP-seq
MIRT1216202	hsa-miR-4498	CLIP-seq
MIRT2290848	hsa-miR-4504	CLIP-seq
MIRT1216203	hsa-miR-450b-3p	CLIP-seq
MIRT2290849	hsa-miR-4512	CLIP-seq
MIRT1216204	hsa-miR-4516	CLIP-seq
MIRT2290850	hsa-miR-4525	CLIP-seq
MIRT2290851	hsa-miR-4533	CLIP-seq
MIRT2290852	hsa-miR-4649-3p	CLIP-seq
MIRT2290853	hsa-miR-4651	CLIP-seq
MIRT2290854	hsa-miR-4653-3p	CLIP-seq
MIRT2290855	hsa-miR-4664-5p	CLIP-seq
MIRT2290856	hsa-miR-4677-3p	CLIP-seq
MIRT1216207	hsa-miR-4682	CLIP-seq
MIRT2290857	hsa-miR-4685-5p	CLIP-seq
MIRT1216208	hsa-miR-4693-5p	CLIP-seq
MIRT2290858	hsa-miR-4708-3p	CLIP-seq
MIRT1216209	hsa-miR-4713-3p	CLIP-seq
MIRT2062444	hsa-miR-4713-5p	CLIP-seq
MIRT2290859	hsa-miR-4716-3p	CLIP-seq
MIRT2062445	hsa-miR-4723-3p	CLIP-seq
MIRT2290860	hsa-miR-4726-3p	CLIP-seq
MIRT2290861	hsa-miR-4731-3p	CLIP-seq
MIRT2062446	hsa-miR-4731-5p	CLIP-seq
MIRT2062447	hsa-miR-4739	CLIP-seq
MIRT2290862	hsa-miR-4751	CLIP-seq
MIRT1216210	hsa-miR-4753-5p	CLIP-seq
MIRT2062448	hsa-miR-4756-5p	CLIP-seq
MIRT2290863	hsa-miR-4762-5p	CLIP-seq
MIRT2290864	hsa-miR-4763-3p	CLIP-seq
MIRT1216211	hsa-miR-4772-3p	CLIP-seq
MIRT2062449	hsa-miR-4786-3p	CLIP-seq
MIRT1216212	hsa-miR-4796-3p	CLIP-seq
MIRT2290865	hsa-miR-4797-5p	CLIP-seq
MIRT2290866	hsa-miR-4801	CLIP-seq
MIRT1216213	hsa-miR-483-5p	CLIP-seq
MIRT2290867	hsa-miR-484	CLIP-seq
MIRT1216214	hsa-miR-489	CLIP-seq
MIRT2290868	hsa-miR-491-5p	CLIP-seq
MIRT1216216	hsa-miR-496	CLIP-seq
MIRT2062450	hsa-miR-513a-5p	CLIP-seq
MIRT2290869	hsa-miR-515-3p	CLIP-seq
MIRT1216218	hsa-miR-519d	CLIP-seq
MIRT2290870	hsa-miR-519e	CLIP-seq
MIRT2062451	hsa-miR-532-3p	CLIP-seq
MIRT1216219	hsa-miR-548ah	CLIP-seq
MIRT2290871	hsa-miR-548al	CLIP-seq
MIRT2290872	hsa-miR-548p	CLIP-seq
MIRT2290873	hsa-miR-548v	CLIP-seq
MIRT2290874	hsa-miR-554	CLIP-seq
MIRT2290875	hsa-miR-577	CLIP-seq
MIRT2062452	hsa-miR-582-5p	CLIP-seq
MIRT1216221	hsa-miR-586	CLIP-seq
MIRT2290876	hsa-miR-605	CLIP-seq
MIRT2290877	hsa-miR-608	CLIP-seq
MIRT2290878	hsa-miR-618	CLIP-seq
MIRT1216222	hsa-miR-627	CLIP-seq
MIRT1216223	hsa-miR-638	CLIP-seq
MIRT2290879	hsa-miR-665	CLIP-seq
MIRT1216224	hsa-miR-762	CLIP-seq
MIRT1216225	hsa-miR-769-3p	CLIP-seq
MIRT1216226	hsa-miR-892a	CLIP-seq
MIRT1216227	hsa-miR-924	CLIP-seq
MIRT1216228	hsa-miR-93	CLIP-seq
MIRT2290880	hsa-miR-940	CLIP-seq
MIRT2062428	hsa-miR-1321	CLIP-seq
MIRT2062430	hsa-miR-150	CLIP-seq
MIRT1216181	hsa-miR-153	CLIP-seq
MIRT1216184	hsa-miR-1915	CLIP-seq
MIRT2290830	hsa-miR-3151	CLIP-seq
MIRT2062441	hsa-miR-3689d	CLIP-seq
MIRT1216198	hsa-miR-4434	CLIP-seq
MIRT1216200	hsa-miR-448	CLIP-seq
MIRT1216204	hsa-miR-4516	CLIP-seq
MIRT2290853	hsa-miR-4651	CLIP-seq
MIRT2062444	hsa-miR-4713-5p	CLIP-seq
MIRT2290860	hsa-miR-4726-3p	CLIP-seq
MIRT2062447	hsa-miR-4739	CLIP-seq
MIRT2062448	hsa-miR-4756-5p	CLIP-seq
MIRT2062449	hsa-miR-4786-3p	CLIP-seq
MIRT1216213	hsa-miR-483-5p	CLIP-seq
MIRT1216216	hsa-miR-496	CLIP-seq
MIRT2062451	hsa-miR-532-3p	CLIP-seq
MIRT2290877	hsa-miR-608	CLIP-seq
MIRT2290821	hsa-miR-1207-5p	CLIP-seq
MIRT2290823	hsa-miR-1254	CLIP-seq
MIRT1216176	hsa-miR-138	CLIP-seq
MIRT1216178	hsa-miR-148a	CLIP-seq
MIRT1216179	hsa-miR-148b	CLIP-seq
MIRT1216180	hsa-miR-152	CLIP-seq
MIRT2290825	hsa-miR-1825	CLIP-seq
MIRT1216183	hsa-miR-1909	CLIP-seq
MIRT2290829	hsa-miR-3116	CLIP-seq
MIRT2290830	hsa-miR-3151	CLIP-seq
MIRT2290835	hsa-miR-342-5p	CLIP-seq
MIRT1216193	hsa-miR-3913-3p	CLIP-seq
MIRT2439213	hsa-miR-4269	CLIP-seq
MIRT1216196	hsa-miR-4299	CLIP-seq
MIRT1216197	hsa-miR-4318	CLIP-seq
MIRT1216199	hsa-miR-4446-3p	CLIP-seq
MIRT2290845	hsa-miR-4447	CLIP-seq
MIRT2290846	hsa-miR-4455	CLIP-seq
MIRT2290847	hsa-miR-4472	CLIP-seq
MIRT1216201	hsa-miR-4492	CLIP-seq
MIRT1216202	hsa-miR-4498	CLIP-seq
MIRT2439214	hsa-miR-4514	CLIP-seq
MIRT2290853	hsa-miR-4651	CLIP-seq
MIRT2290855	hsa-miR-4664-5p	CLIP-seq
MIRT2439215	hsa-miR-4692	CLIP-seq
MIRT1216208	hsa-miR-4693-5p	CLIP-seq
MIRT2439216	hsa-miR-4742-5p	CLIP-seq
MIRT2290864	hsa-miR-4763-3p	CLIP-seq
MIRT1216214	hsa-miR-489	CLIP-seq
MIRT2290868	hsa-miR-491-5p	CLIP-seq
MIRT2290869	hsa-miR-515-3p	CLIP-seq
MIRT2290870	hsa-miR-519e	CLIP-seq
MIRT2439217	hsa-miR-550a	CLIP-seq
MIRT2290877	hsa-miR-608	CLIP-seq
MIRT2439218	hsa-miR-661	CLIP-seq
MIRT2439219	hsa-miR-711	CLIP-seq
MIRT1216224	hsa-miR-762	CLIP-seq
MIRT1216226	hsa-miR-892a	CLIP-seq
MIRT2290880	hsa-miR-940	CLIP-seq
MIRT2588560	hsa-miR-335	CLIP-seq
MIRT2588561	hsa-miR-3605-5p	CLIP-seq
MIRT2290840	hsa-miR-4297	CLIP-seq
MIRT2062430	hsa-miR-150	CLIP-seq
MIRT2290828	hsa-miR-2355-5p	CLIP-seq
MIRT2062438	hsa-miR-3127-3p	CLIP-seq
MIRT2290831	hsa-miR-3155	CLIP-seq
MIRT2290832	hsa-miR-3155b	CLIP-seq
MIRT2062440	hsa-miR-3183	CLIP-seq
MIRT2588560	hsa-miR-335	CLIP-seq
MIRT2588561	hsa-miR-3605-5p	CLIP-seq
MIRT2062442	hsa-miR-4268	CLIP-seq
MIRT2290840	hsa-miR-4297	CLIP-seq
MIRT2290844	hsa-miR-4438	CLIP-seq
MIRT2062444	hsa-miR-4713-5p	CLIP-seq
MIRT2062445	hsa-miR-4723-3p	CLIP-seq
MIRT2290867	hsa-miR-484	CLIP-seq
MIRT2062451	hsa-miR-532-3p	CLIP-seq

Show/Hide all (4)

Transcription factor	Regulation	Reference
CTCF	Unknown	22187427
CTCF	Unknown	22187427
GATA1	Unknown	22187427
GATA1	Unknown	22187427

Show/Hide all (28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	IEA
GO:0002532	Process	Production of molecular mediator involved in inflammatory response	IEA
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0003713	Function	Transcription coactivator activity	IEA
GO:0003714	Function	Transcription corepressor activity	IDA	10825160
GO:0005515	Function	Protein binding	IPI	16189514, 17043237, 19060904, 25416956, 29892012, 31515488, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	10825160
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005667	Component	Transcription regulator complex	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	10825160
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0010467	Process	Gene expression	IEA
GO:0016477	Process	Cell migration	IEA
GO:0022617	Process	Extracellular matrix disassembly	IEA
GO:0030097	Process	Hemopoiesis	IEP	10825160
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	10825160
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0061975	Process	Articular cartilage development	IEA
GO:0140297	Function	DNA-binding transcription factor binding	IPI	10825160
GO:1901148	Process	Gene expression involved in extracellular matrix organization	IEA
GO:1902732	Process	Positive regulation of chondrocyte proliferation	IEA

MIM	HGNC	e!Ensembl
618819	21199	ENSG00000163346

Q96AQ6

Protein name

Pre-B-cell leukemia transcription factor-interacting protein 1 (Hematopoietic PBX-interacting protein)

Protein function

Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them t

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Expressed in early hematopoietic precursors. {ECO:0000269|PubMed:10825160}.

Sequence

MASCPDSDNSWVLAGSESLPVETLGPASRMDPESERALQAPHSPSKTDGKELAGTMDGEG
TLFQTESPQSGSILTEETEVKGTLEGDVCGVEPPGPGDTVVQGDLQETTVVTGLGPDTQD
LEGQSPPQSLPSTPKAAWIREEGRCSSSDDDTDVDMEGLRRRRGREAGPPQPMVPLAVEN
QAGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQVLPDPEVLE
AVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLM
HQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGP
QGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDAS
RGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWD
GQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKE
PPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECARQEGL
TFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFFGEDGIFRHDRLRFRDFV
DALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHSQSPRAAGPREG
HSHSHHHHHRG

Sequence length

731

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CARDIAC EMBOLISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOEMBOLIC STROKE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, KNEE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARKINSON DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (30)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	36776048	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Anemia Sickle Cell	Sickle cell anemia	Pubtator	23593351	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	Pubtator	24470547	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	18302941, 25486428		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	37294756	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	28975986	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	28075456		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	27178820		★★★★★ ★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	28894377, 30033330		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	28894377, 30033330		★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	30659184		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ductal Breast Carcinoma	Breast Carcinoma	BEFREE	25486428		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ductal Carcinoma	Ductal Carcinoma	BEFREE	25486428		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	31241209	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	26590606	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	24470547	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	28975986		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	37294756	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	31241209	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	18302941, 25486428		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	28075456		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	27178820		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28075456		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	28894377, 30033330		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	27458096		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	27178820, 28039608		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	27178820	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	Lymphoblastic Leukemia	BEFREE	27178820, 27458096, 28075456		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	27458096		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	26211905	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only

PBXIP1 (PBX homeobox interacting protein 1)