Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5724
Gene name	Platelet activating factor receptor
Gene symbol	PTAFR
Synonyms (NCBI Gene)	PAFR
Chromosome	1
Chromosome location	1p35.3
Summary	This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that play

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017043	hsa-miR-335-5p	Microarray	18185580
MIRT632521	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT666785	hsa-miR-5193	HITS-CLIP	23824327
MIRT632520	hsa-miR-1281	HITS-CLIP	23824327
MIRT666784	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT632519	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT632518	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT632517	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT654638	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT654653	hsa-miR-562	HITS-CLIP	23824327
MIRT654652	hsa-miR-5697	HITS-CLIP	23824327
MIRT654651	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT654649	hsa-miR-4301	HITS-CLIP	23824327
MIRT654650	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT654648	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT654647	hsa-miR-8073	HITS-CLIP	23824327
MIRT654646	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT654645	hsa-miR-149-5p	HITS-CLIP	23824327
MIRT654644	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT654643	hsa-miR-4284	HITS-CLIP	23824327
MIRT654642	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT654641	hsa-miR-3157-5p	HITS-CLIP	23824327
MIRT654640	hsa-miR-188-3p	HITS-CLIP	23824327
MIRT654639	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT654638	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639950	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT639949	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT639948	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT632521	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT632520	hsa-miR-1281	HITS-CLIP	23824327
MIRT632519	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT632518	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT632517	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT516036	hsa-miR-4463	PAR-CLIP	23446348
MIRT516035	hsa-miR-4494	PAR-CLIP	23446348
MIRT516034	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT516033	hsa-miR-3663-5p	PAR-CLIP	23446348
MIRT516032	hsa-miR-4635	PAR-CLIP	23446348
MIRT516031	hsa-miR-6788-3p	PAR-CLIP	23446348
MIRT738998	hsa-miR-1291	HITS-CLIP	33718276
MIRT738999	hsa-miR-328	HITS-CLIP	33718276
MIRT632521	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT666785	hsa-miR-5193	HITS-CLIP	23824327
MIRT632520	hsa-miR-1281	HITS-CLIP	23824327
MIRT666784	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT632519	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT632518	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT632517	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT654638	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT654653	hsa-miR-562	HITS-CLIP	23824327
MIRT654652	hsa-miR-5697	HITS-CLIP	23824327
MIRT654651	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT654649	hsa-miR-4301	HITS-CLIP	23824327
MIRT654650	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT654648	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT654647	hsa-miR-8073	HITS-CLIP	23824327
MIRT654646	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT654645	hsa-miR-149-5p	HITS-CLIP	23824327
MIRT654644	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT654643	hsa-miR-4284	HITS-CLIP	23824327
MIRT654642	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT654641	hsa-miR-3157-5p	HITS-CLIP	23824327
MIRT654640	hsa-miR-188-3p	HITS-CLIP	23824327
MIRT654639	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT654638	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639950	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT639949	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT639948	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT632521	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT632520	hsa-miR-1281	HITS-CLIP	23824327
MIRT632519	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT632518	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT632517	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT516036	hsa-miR-4463	PAR-CLIP	23446348
MIRT516035	hsa-miR-4494	PAR-CLIP	23446348
MIRT516034	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT516033	hsa-miR-3663-5p	PAR-CLIP	23446348
MIRT516032	hsa-miR-4635	PAR-CLIP	23446348
MIRT516031	hsa-miR-6788-3p	PAR-CLIP	23446348
MIRT1271284	hsa-miR-106a	CLIP-seq
MIRT1271285	hsa-miR-106b	CLIP-seq
MIRT1271286	hsa-miR-1200	CLIP-seq
MIRT1271287	hsa-miR-1224-3p	CLIP-seq
MIRT1271288	hsa-miR-1225-3p	CLIP-seq
MIRT1271289	hsa-miR-1227	CLIP-seq
MIRT1271290	hsa-miR-1233	CLIP-seq
MIRT1271291	hsa-miR-125a-3p	CLIP-seq
MIRT1271292	hsa-miR-1279	CLIP-seq
MIRT1271293	hsa-miR-1307	CLIP-seq
MIRT1271294	hsa-miR-1321	CLIP-seq
MIRT1271295	hsa-miR-139-3p	CLIP-seq
MIRT1271296	hsa-miR-150	CLIP-seq
MIRT1271297	hsa-miR-17	CLIP-seq
MIRT1271298	hsa-miR-185	CLIP-seq
MIRT1271299	hsa-miR-1915	CLIP-seq
MIRT1271300	hsa-miR-1976	CLIP-seq
MIRT1271301	hsa-miR-20a	CLIP-seq
MIRT1271302	hsa-miR-20b	CLIP-seq
MIRT1271303	hsa-miR-2276	CLIP-seq
MIRT1271304	hsa-miR-2278	CLIP-seq
MIRT1271305	hsa-miR-2355-5p	CLIP-seq
MIRT1271306	hsa-miR-2467-5p	CLIP-seq
MIRT1271307	hsa-miR-302a	CLIP-seq
MIRT1271308	hsa-miR-302b	CLIP-seq
MIRT1271309	hsa-miR-302c	CLIP-seq
MIRT1271310	hsa-miR-302d	CLIP-seq
MIRT1271311	hsa-miR-302e	CLIP-seq
MIRT739000	hsa-miR-3130-3p	CLIP-seq
MIRT1271312	hsa-miR-3135b	CLIP-seq
MIRT1271313	hsa-miR-3150b-3p	CLIP-seq
MIRT1271314	hsa-miR-3155	CLIP-seq
MIRT1271315	hsa-miR-3155b	CLIP-seq
MIRT1271316	hsa-miR-3166	CLIP-seq
MIRT1271317	hsa-miR-3188	CLIP-seq
MIRT1271318	hsa-miR-3199	CLIP-seq
MIRT739003	hsa-miR-361-3p	CLIP-seq
MIRT1271319	hsa-miR-3616-3p	CLIP-seq
MIRT1271320	hsa-miR-3652	CLIP-seq
MIRT1271321	hsa-miR-3660	CLIP-seq
MIRT1271322	hsa-miR-3664-5p	CLIP-seq
MIRT739004	hsa-miR-3679-3p	CLIP-seq
MIRT1271323	hsa-miR-370	CLIP-seq
MIRT1271324	hsa-miR-371-5p	CLIP-seq
MIRT1271325	hsa-miR-371b-5p	CLIP-seq
MIRT1271326	hsa-miR-372	CLIP-seq
MIRT1271327	hsa-miR-373	CLIP-seq
MIRT1271328	hsa-miR-377	CLIP-seq
MIRT1271329	hsa-miR-3975	CLIP-seq
MIRT1271330	hsa-miR-4252	CLIP-seq
MIRT1271331	hsa-miR-4268	CLIP-seq
MIRT1271332	hsa-miR-4279	CLIP-seq
MIRT1271333	hsa-miR-4306	CLIP-seq
MIRT1271334	hsa-miR-4312	CLIP-seq
MIRT1271335	hsa-miR-4323	CLIP-seq
MIRT1271336	hsa-miR-4324	CLIP-seq
MIRT1271337	hsa-miR-4430	CLIP-seq
MIRT1271338	hsa-miR-4433	CLIP-seq
MIRT1271339	hsa-miR-4438	CLIP-seq
MIRT1271340	hsa-miR-4448	CLIP-seq
MIRT1271341	hsa-miR-4459	CLIP-seq
MIRT1271342	hsa-miR-4519	CLIP-seq
MIRT1271343	hsa-miR-4526	CLIP-seq
MIRT739002	hsa-miR-4527	CLIP-seq
MIRT1271344	hsa-miR-4638-5p	CLIP-seq
MIRT1271345	hsa-miR-4639-3p	CLIP-seq
MIRT1271346	hsa-miR-4644	CLIP-seq
MIRT1271347	hsa-miR-4645-3p	CLIP-seq
MIRT1271348	hsa-miR-4649-3p	CLIP-seq
MIRT1271349	hsa-miR-4653-3p	CLIP-seq
MIRT1271350	hsa-miR-4695-3p	CLIP-seq
MIRT1271351	hsa-miR-4706	CLIP-seq
MIRT1271352	hsa-miR-4715-3p	CLIP-seq
MIRT1271353	hsa-miR-4722-3p	CLIP-seq
MIRT1271354	hsa-miR-4726-3p	CLIP-seq
MIRT1271355	hsa-miR-4731-5p	CLIP-seq
MIRT1271356	hsa-miR-4739	CLIP-seq
MIRT1271357	hsa-miR-4749-5p	CLIP-seq
MIRT1271358	hsa-miR-4755-3p	CLIP-seq
MIRT1271359	hsa-miR-4756-5p	CLIP-seq
MIRT1271360	hsa-miR-4757-5p	CLIP-seq
MIRT1271361	hsa-miR-4763-5p	CLIP-seq
MIRT1271362	hsa-miR-4768-3p	CLIP-seq
MIRT1271363	hsa-miR-4784	CLIP-seq
MIRT739001	hsa-miR-4793-3p	CLIP-seq
MIRT1271364	hsa-miR-4797-5p	CLIP-seq
MIRT1271365	hsa-miR-484	CLIP-seq
MIRT1271366	hsa-miR-485-5p	CLIP-seq
MIRT1271367	hsa-miR-498	CLIP-seq
MIRT1271368	hsa-miR-5095	CLIP-seq
MIRT1271369	hsa-miR-512-3p	CLIP-seq
MIRT1271370	hsa-miR-514	CLIP-seq
MIRT1271371	hsa-miR-514b-3p	CLIP-seq
MIRT1271372	hsa-miR-518d-5p	CLIP-seq
MIRT1271373	hsa-miR-519b-5p	CLIP-seq
MIRT1271374	hsa-miR-519c-5p	CLIP-seq
MIRT1271375	hsa-miR-519d	CLIP-seq
MIRT1271376	hsa-miR-520a-3p	CLIP-seq
MIRT1271377	hsa-miR-520b	CLIP-seq
MIRT1271378	hsa-miR-520c-3p	CLIP-seq
MIRT1271379	hsa-miR-520c-5p	CLIP-seq
MIRT1271380	hsa-miR-520d-3p	CLIP-seq
MIRT1271381	hsa-miR-520e	CLIP-seq
MIRT1271382	hsa-miR-520g	CLIP-seq
MIRT1271383	hsa-miR-520h	CLIP-seq
MIRT1271384	hsa-miR-526a	CLIP-seq
MIRT1271385	hsa-miR-544b	CLIP-seq
MIRT1271386	hsa-miR-628-5p	CLIP-seq
MIRT1271387	hsa-miR-642b	CLIP-seq
MIRT1271388	hsa-miR-765	CLIP-seq
MIRT1271389	hsa-miR-93	CLIP-seq
MIRT739000	hsa-miR-3130-3p	CLIP-seq
MIRT739003	hsa-miR-361-3p	CLIP-seq
MIRT739004	hsa-miR-3679-3p	CLIP-seq
MIRT739002	hsa-miR-4527	CLIP-seq
MIRT739001	hsa-miR-4793-3p	CLIP-seq
MIRT739000	hsa-miR-3130-3p	CLIP-seq
MIRT739003	hsa-miR-361-3p	CLIP-seq
MIRT739004	hsa-miR-3679-3p	CLIP-seq
MIRT739002	hsa-miR-4527	CLIP-seq
MIRT739001	hsa-miR-4793-3p	CLIP-seq
MIRT1271286	hsa-miR-1200	CLIP-seq
MIRT2079768	hsa-miR-1252	CLIP-seq
MIRT2079769	hsa-miR-1254	CLIP-seq
MIRT1271291	hsa-miR-125a-3p	CLIP-seq
MIRT2079770	hsa-miR-1273f	CLIP-seq
MIRT2079771	hsa-miR-129-5p	CLIP-seq
MIRT2079772	hsa-miR-143	CLIP-seq
MIRT1271299	hsa-miR-1915	CLIP-seq
MIRT1271300	hsa-miR-1976	CLIP-seq
MIRT2079773	hsa-miR-3116	CLIP-seq
MIRT739000	hsa-miR-3130-3p	CLIP-seq
MIRT2079774	hsa-miR-3176	CLIP-seq
MIRT2079775	hsa-miR-3189-5p	CLIP-seq
MIRT1271318	hsa-miR-3199	CLIP-seq
MIRT2079776	hsa-miR-3202	CLIP-seq
MIRT739003	hsa-miR-361-3p	CLIP-seq
MIRT739004	hsa-miR-3679-3p	CLIP-seq
MIRT2079777	hsa-miR-3687	CLIP-seq
MIRT2079778	hsa-miR-3690	CLIP-seq
MIRT2079779	hsa-miR-3921	CLIP-seq
MIRT2079780	hsa-miR-3922-3p	CLIP-seq
MIRT2079781	hsa-miR-3934	CLIP-seq
MIRT2079782	hsa-miR-4254	CLIP-seq
MIRT1271332	hsa-miR-4279	CLIP-seq
MIRT1271334	hsa-miR-4312	CLIP-seq
MIRT1271336	hsa-miR-4324	CLIP-seq
MIRT1271339	hsa-miR-4438	CLIP-seq
MIRT2079783	hsa-miR-4442	CLIP-seq
MIRT2079784	hsa-miR-4476	CLIP-seq
MIRT739002	hsa-miR-4527	CLIP-seq
MIRT2079785	hsa-miR-4533	CLIP-seq
MIRT2079786	hsa-miR-4638-3p	CLIP-seq
MIRT2079787	hsa-miR-4653-5p	CLIP-seq
MIRT2079788	hsa-miR-4708-5p	CLIP-seq
MIRT1271353	hsa-miR-4722-3p	CLIP-seq
MIRT1271354	hsa-miR-4726-3p	CLIP-seq
MIRT1271360	hsa-miR-4757-5p	CLIP-seq
MIRT2079789	hsa-miR-4758-3p	CLIP-seq
MIRT1271361	hsa-miR-4763-5p	CLIP-seq
MIRT2079790	hsa-miR-4770	CLIP-seq
MIRT739001	hsa-miR-4793-3p	CLIP-seq
MIRT1271367	hsa-miR-498	CLIP-seq
MIRT1271368	hsa-miR-5095	CLIP-seq
MIRT1271385	hsa-miR-544b	CLIP-seq
MIRT2079791	hsa-miR-671-5p	CLIP-seq
MIRT2079792	hsa-miR-7	CLIP-seq
MIRT2079793	hsa-miR-764	CLIP-seq
MIRT2079794	hsa-miR-942	CLIP-seq
MIRT739000	hsa-miR-3130-3p	CLIP-seq
MIRT739003	hsa-miR-361-3p	CLIP-seq
MIRT739004	hsa-miR-3679-3p	CLIP-seq
MIRT739002	hsa-miR-4527	CLIP-seq
MIRT739001	hsa-miR-4793-3p	CLIP-seq
MIRT739000	hsa-miR-3130-3p	CLIP-seq
MIRT739003	hsa-miR-361-3p	CLIP-seq
MIRT739004	hsa-miR-3679-3p	CLIP-seq
MIRT739002	hsa-miR-4527	CLIP-seq
MIRT739001	hsa-miR-4793-3p	CLIP-seq
MIRT1271318	hsa-miR-3199	CLIP-seq
MIRT1271318	hsa-miR-3199	CLIP-seq
MIRT2079771	hsa-miR-129-5p	CLIP-seq
MIRT1271312	hsa-miR-3135b	CLIP-seq
MIRT2465922	hsa-miR-3149	CLIP-seq
MIRT1271320	hsa-miR-3652	CLIP-seq
MIRT1271322	hsa-miR-3664-5p	CLIP-seq
MIRT2465923	hsa-miR-411	CLIP-seq
MIRT1271337	hsa-miR-4430	CLIP-seq
MIRT1271345	hsa-miR-4639-3p	CLIP-seq
MIRT2465924	hsa-miR-4735-5p	CLIP-seq
MIRT1271358	hsa-miR-4755-3p	CLIP-seq
MIRT2465925	hsa-miR-4775	CLIP-seq
MIRT1271364	hsa-miR-4797-5p	CLIP-seq
MIRT2465926	hsa-miR-483-5p	CLIP-seq
MIRT2465927	hsa-miR-590-3p	CLIP-seq
MIRT1271387	hsa-miR-642b	CLIP-seq
MIRT1271284	hsa-miR-106a	CLIP-seq
MIRT1271285	hsa-miR-106b	CLIP-seq
MIRT1271286	hsa-miR-1200	CLIP-seq
MIRT1271289	hsa-miR-1227	CLIP-seq
MIRT1271291	hsa-miR-125a-3p	CLIP-seq
MIRT2079771	hsa-miR-129-5p	CLIP-seq
MIRT2603432	hsa-miR-140-3p	CLIP-seq
MIRT1271296	hsa-miR-150	CLIP-seq
MIRT1271297	hsa-miR-17	CLIP-seq
MIRT1271298	hsa-miR-185	CLIP-seq
MIRT1271299	hsa-miR-1915	CLIP-seq
MIRT1271300	hsa-miR-1976	CLIP-seq
MIRT1271301	hsa-miR-20a	CLIP-seq
MIRT1271302	hsa-miR-20b	CLIP-seq
MIRT2603433	hsa-miR-297	CLIP-seq
MIRT1271307	hsa-miR-302a	CLIP-seq
MIRT1271308	hsa-miR-302b	CLIP-seq
MIRT1271309	hsa-miR-302c	CLIP-seq
MIRT1271310	hsa-miR-302d	CLIP-seq
MIRT1271311	hsa-miR-302e	CLIP-seq
MIRT1271312	hsa-miR-3135b	CLIP-seq
MIRT2465922	hsa-miR-3149	CLIP-seq
MIRT1271318	hsa-miR-3199	CLIP-seq
MIRT1271320	hsa-miR-3652	CLIP-seq
MIRT1271322	hsa-miR-3664-5p	CLIP-seq
MIRT1271326	hsa-miR-372	CLIP-seq
MIRT1271327	hsa-miR-373	CLIP-seq
MIRT2079781	hsa-miR-3934	CLIP-seq
MIRT2465923	hsa-miR-411	CLIP-seq
MIRT1271332	hsa-miR-4279	CLIP-seq
MIRT1271333	hsa-miR-4306	CLIP-seq
MIRT1271334	hsa-miR-4312	CLIP-seq
MIRT1271336	hsa-miR-4324	CLIP-seq
MIRT1271337	hsa-miR-4430	CLIP-seq
MIRT1271339	hsa-miR-4438	CLIP-seq
MIRT2603434	hsa-miR-4468	CLIP-seq
MIRT1271345	hsa-miR-4639-3p	CLIP-seq
MIRT1271346	hsa-miR-4644	CLIP-seq
MIRT2603435	hsa-miR-4684-5p	CLIP-seq
MIRT1271352	hsa-miR-4715-3p	CLIP-seq
MIRT1271353	hsa-miR-4722-3p	CLIP-seq
MIRT1271354	hsa-miR-4726-3p	CLIP-seq
MIRT1271355	hsa-miR-4731-5p	CLIP-seq
MIRT2465924	hsa-miR-4735-5p	CLIP-seq
MIRT1271358	hsa-miR-4755-3p	CLIP-seq
MIRT1271360	hsa-miR-4757-5p	CLIP-seq
MIRT1271361	hsa-miR-4763-5p	CLIP-seq
MIRT2603436	hsa-miR-4768-5p	CLIP-seq
MIRT2465925	hsa-miR-4775	CLIP-seq
MIRT1271364	hsa-miR-4797-5p	CLIP-seq
MIRT2465926	hsa-miR-483-5p	CLIP-seq
MIRT1271367	hsa-miR-498	CLIP-seq
MIRT1271368	hsa-miR-5095	CLIP-seq
MIRT1271369	hsa-miR-512-3p	CLIP-seq
MIRT1271375	hsa-miR-519d	CLIP-seq
MIRT1271376	hsa-miR-520a-3p	CLIP-seq
MIRT1271377	hsa-miR-520b	CLIP-seq
MIRT1271378	hsa-miR-520c-3p	CLIP-seq
MIRT1271380	hsa-miR-520d-3p	CLIP-seq
MIRT1271381	hsa-miR-520e	CLIP-seq
MIRT1271382	hsa-miR-520g	CLIP-seq
MIRT1271383	hsa-miR-520h	CLIP-seq
MIRT1271385	hsa-miR-544b	CLIP-seq
MIRT2603437	hsa-miR-567	CLIP-seq
MIRT2465927	hsa-miR-590-3p	CLIP-seq
MIRT1271387	hsa-miR-642b	CLIP-seq
MIRT2079793	hsa-miR-764	CLIP-seq
MIRT1271389	hsa-miR-93	CLIP-seq
MIRT1271286	hsa-miR-1200	CLIP-seq
MIRT1271299	hsa-miR-1915	CLIP-seq
MIRT1271300	hsa-miR-1976	CLIP-seq
MIRT1271318	hsa-miR-3199	CLIP-seq
MIRT1271332	hsa-miR-4279	CLIP-seq
MIRT1271336	hsa-miR-4324	CLIP-seq
MIRT1271353	hsa-miR-4722-3p	CLIP-seq
MIRT1271354	hsa-miR-4726-3p	CLIP-seq
MIRT1271367	hsa-miR-498	CLIP-seq
MIRT1271385	hsa-miR-544b	CLIP-seq

Show/Hide all (3)

Transcription factor	Regulation	Reference
NFKB1	Activation	11502209
NR1I2	Activation	19703903
RELA	Activation	11502209

Show/Hide all (30)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001530	Function	Lipopolysaccharide binding	IEA
GO:0001875	Function	Lipopolysaccharide immune receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	TAS	1322356
GO:0004992	Function	Platelet activating factor receptor activity	IDA	1281995, 1656963, 1657923
GO:0004992	Function	Platelet activating factor receptor activity	IEA
GO:0004992	Function	Platelet activating factor receptor activity	TAS	10601267
GO:0005515	Function	Protein binding	IPI	20576130
GO:0005543	Function	Phospholipid binding	IDA	1656963, 1657923
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	8168510
GO:0006935	Process	Chemotaxis	IEA
GO:0006935	Process	Chemotaxis	TAS	10601267
GO:0006954	Process	Inflammatory response	IEA
GO:0006954	Process	Inflammatory response	TAS	8978777
GO:0006955	Process	Immune response	TAS	8892648
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IBA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS	10601267
GO:0007200	Process	Phospholipase C-activating G protein-coupled receptor signaling pathway	IMP	1657923
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	1281995, 1656963
GO:0030667	Component	Secretory granule membrane	TAS
GO:0031663	Process	Lipopolysaccharide-mediated signaling pathway	IEA
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0032959	Process	Inositol trisphosphate biosynthetic process	IEA
GO:0035589	Process	G protein-coupled purinergic nucleotide receptor signaling pathway	IEA
GO:0045028	Function	G protein-coupled purinergic nucleotide receptor activity	IBA
GO:0070821	Component	Tertiary granule membrane	TAS

MIM	HGNC	e!Ensembl
173393	9582	ENSG00000169403

P25105

Protein name

Platelet-activating factor receptor (PAF-R) (PAFr)

Protein function

Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinosito

PDB

5ZKP , 5ZKQ , 8XYD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00001	7tm_1	32 → 293	7 transmembrane receptor (rhodopsin family)	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes. {ECO:0000269|PubMed:1281995, ECO:0000269|PubMed:1656963, ECO:0000269|PubMed:1657923}.

Sequence

MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN

Sequence length

342

Interactions

View interactions

	KEGG		Reactome
	Calcium signaling pathway Neuroactive ligand-receptor interaction Staphylococcus aureus infection		Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events Interleukin-10 signaling Neutrophil degranulation Interferon gamma signaling

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CROHN DISEASE	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CROHNS DISEASE OF LARGE BOWEL	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POLYCYSTIC OVARY SYNDROME	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (72)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adult Oligodendroglioma	Oligodendroglioma	BEFREE	29890994		★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	29472887		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	11085958, 16386258		★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	28667161, 29808000, 30976089		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	11085958, 16386258		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	Pubtator	11171098, 22570732	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	26359459		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	16718768	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	34571986	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	24921917, 25261977, 30340558		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	BEFREE	29808000		★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood Oligodendroglioma	Oligodendroglioma	BEFREE	29890994		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	26662379, 29088819, 30976089, 31663668		★★★★★ ★☆☆☆☆ Found in Text Mining only
CNS disorder	CNS Disorder	BEFREE	27613281		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	30976089		★★★★★ ★☆☆☆☆ Found in Text Mining only
Corneal Neovascularization	Corneal Neovascularization	BEFREE	24754407		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	28197937		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	BEFREE	28197937		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	Pubtator	33506919	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary heart disease	Coronary Heart Disease	BEFREE	28197937		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatitis Atopic	Atopic dermatitis	Pubtator	12605696	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	29247656		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathies	Diabetic neuropathy	Pubtator	29207067	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathy	Diabetic Nephropathy	BEFREE	29207067, 29247656		★★★★★ ★☆☆☆☆ Found in Text Mining only
Disseminated Intravascular Coagulation	Disseminated Intravascular Coagulation	BEFREE	31442556		★★★★★ ★☆☆☆☆ Found in Text Mining only
Erectile dysfunction	Erectile Dysfunction	BEFREE	25343742		★★★★★ ★☆☆☆☆ Found in Text Mining only
Erectile Dysfunction	Erectile dysfunction	Pubtator	25343742	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	33371165	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Graft-vs-Host Disease	Graft-Vs-Host Disease	BEFREE	22301794		★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	30976089		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ischemic Stroke	Ischemic stroke	Pubtator	37435773	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	LHGDN	16837045		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	19615424		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lissencephaly	Lissencephaly	BEFREE	16549273		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Neoplasms	Liver neoplasm	Pubtator	37101794	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	33198218, 35743223	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphangioma, Cystic	Cystic hygroma	BEFREE	28102879		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	24921917, 25261977, 30340558		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	30577630		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	27176648, 28099922		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of skin	Skin cancer	BEFREE	30314274		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	12467527		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanocytic nevus	Melanocytic nevus	BEFREE	30314274		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	19703903	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	28636992, 30314274		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple Sclerosis	BEFREE	15748960		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple Sclerosis	LHGDN	15748960		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple sclerosis	Pubtator	33278709	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial infarction	Pubtator	33506919	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasal Polyps	Nasal polyp	Pubtator	33135871	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	28636992		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	24921917, 29459885, 30314274, 30328954, 9603913		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neutrophilia (disorder)	Neutrophilia	BEFREE	30976089		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	26359459		★★★★★ ★☆☆☆☆ Found in Text Mining only
oligodendroglioma	Oligodendroglioma	BEFREE	29890994		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oligodendroglioma	Oligodendroglioma	Pubtator	29890994	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	LHGDN	18632638		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	24921917, 25261977, 30340558		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	18632638, 25261977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	20576130, 34571986	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	30577630		★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	CTD_human_DG	21411543		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate carcinoma	Prostate cancer	BEFREE	27176648, 28099922		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	24685340, 25143722	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	27524890	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Respiratory Tract Infections	Respiratory system infectious disease	Pubtator	27524890	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Sclerocystic Ovaries	Sclerocystic Ovaries	CTD_human_DG	21411543		★★★★★ ★☆☆☆☆ Found in Text Mining only
Skin carcinoma	Skin Carcinoma	BEFREE	30314274		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	29459885		★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	30756528, 36806529	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Well Differentiated Oligodendroglioma	Oligodendroglioma	BEFREE	29890994		★★★★★ ★☆☆☆☆ Found in Text Mining only
Xeroderma Pigmentosum	Xeroderma Pigmentosum	BEFREE	22303003		★★★★★ ★☆☆☆☆ Found in Text Mining only

PTAFR (platelet activating factor receptor)