Gene Gene information from NCBI Gene database.
Entrez ID 57226
Gene name LYR motif containing 2
Gene symbol LYRM2
Synonyms (NCBI Gene)
DJ122O8.2
Chromosome 6
Chromosome location 6q15
miRNA miRNA information provided by mirtarbase database.
1344
miRTarBase ID miRNA Experiments Reference
MIRT048166 hsa-miR-196a-5p CLASH 23622248
MIRT047951 hsa-miR-30c-5p CLASH 23622248
MIRT036790 hsa-miR-760 CLASH 23622248
MIRT656574 hsa-miR-1264 HITS-CLIP 23824327
MIRT656573 hsa-miR-6892-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 31515488
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IBA
GO:0005739 Component Mitochondrion IEA
GO:0032981 Process Mitochondrial respiratory chain complex I assembly IMP 31666358
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NU23
Protein name LYR motif-containing protein 2
Protein function Involved in efficient integration of the N-module into mitochondrial respiratory chain complex I.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05347 Complex1_LYR 20 78 Complex 1 protein (LYR family) Family
Sequence
Sequence length 88
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
BIPOLAR DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Colorectal Carcinoma Colorectal Cancer BEFREE 31004700
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 31004700
★☆☆☆☆
Found in Text Mining only
Osteoporosis Osteoporosis Pubtator 34252604 Associate
★☆☆☆☆
Found in Text Mining only