Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	57210
Gene name	Solute carrier family 45 member 4
Gene symbol	SLC45A4
Synonyms (NCBI Gene)	-
Chromosome	8
Chromosome location	8q24.3

Show/Hide all (88)

miRTarBase ID	miRNA	Experiments	Reference
MIRT707886	hsa-miR-203a-3p	HITS-CLIP	21572407
MIRT707885	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT707884	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT448469	hsa-miR-4635	HITS-CLIP	21572407
MIRT707883	hsa-miR-1301-5p	HITS-CLIP	21572407
MIRT707882	hsa-miR-6502-5p	HITS-CLIP	21572407
MIRT707881	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707880	hsa-miR-5691	HITS-CLIP	21572407
MIRT707879	hsa-miR-6805-3p	HITS-CLIP	21572407
MIRT448471	hsa-miR-1264	PAR-CLIP	22100165
MIRT448469	hsa-miR-4635	PAR-CLIP	22100165
MIRT448470	hsa-miR-2116-5p	PAR-CLIP	22100165
MIRT448468	hsa-miR-22-5p	PAR-CLIP	22100165
MIRT448467	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT448466	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448465	hsa-miR-573	PAR-CLIP	22100165
MIRT448464	hsa-miR-4677-5p	PAR-CLIP	22100165
MIRT448471	hsa-miR-1264	PAR-CLIP	22100165
MIRT448469	hsa-miR-4635	PAR-CLIP	22100165
MIRT448470	hsa-miR-2116-5p	PAR-CLIP	22100165
MIRT448468	hsa-miR-22-5p	PAR-CLIP	22100165
MIRT448467	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT448466	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448465	hsa-miR-573	PAR-CLIP	22100165
MIRT448464	hsa-miR-4677-5p	PAR-CLIP	22100165
MIRT707886	hsa-miR-203a-3p	HITS-CLIP	21572407
MIRT707885	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT707884	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT448469	hsa-miR-4635	HITS-CLIP	21572407
MIRT707883	hsa-miR-1301-5p	HITS-CLIP	21572407
MIRT707882	hsa-miR-6502-5p	HITS-CLIP	21572407
MIRT707881	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707880	hsa-miR-5691	HITS-CLIP	21572407
MIRT707879	hsa-miR-6805-3p	HITS-CLIP	21572407
MIRT448471	hsa-miR-1264	PAR-CLIP	22100165
MIRT448469	hsa-miR-4635	PAR-CLIP	22100165
MIRT448470	hsa-miR-2116-5p	PAR-CLIP	22100165
MIRT448468	hsa-miR-22-5p	PAR-CLIP	22100165
MIRT448467	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT448466	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448465	hsa-miR-573	PAR-CLIP	22100165
MIRT448464	hsa-miR-4677-5p	PAR-CLIP	22100165
MIRT448471	hsa-miR-1264	PAR-CLIP	22100165
MIRT448469	hsa-miR-4635	PAR-CLIP	22100165
MIRT448470	hsa-miR-2116-5p	PAR-CLIP	22100165
MIRT448468	hsa-miR-22-5p	PAR-CLIP	22100165
MIRT448467	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT448466	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448465	hsa-miR-573	PAR-CLIP	22100165
MIRT448464	hsa-miR-4677-5p	PAR-CLIP	22100165
MIRT1364525	hsa-miR-106a	CLIP-seq
MIRT1364526	hsa-miR-106b	CLIP-seq
MIRT1364527	hsa-miR-17	CLIP-seq
MIRT1364528	hsa-miR-20a	CLIP-seq
MIRT1364529	hsa-miR-20b	CLIP-seq
MIRT1364530	hsa-miR-3973	CLIP-seq
MIRT1364531	hsa-miR-519a	CLIP-seq
MIRT1364532	hsa-miR-519b-3p	CLIP-seq
MIRT1364533	hsa-miR-519c-3p	CLIP-seq
MIRT1364534	hsa-miR-519d	CLIP-seq
MIRT1364535	hsa-miR-520g	CLIP-seq
MIRT1364536	hsa-miR-520h	CLIP-seq
MIRT1364537	hsa-miR-93	CLIP-seq
MIRT2108174	hsa-miR-1303	CLIP-seq
MIRT2108175	hsa-miR-2355-5p	CLIP-seq
MIRT2108176	hsa-miR-299-5p	CLIP-seq
MIRT2108177	hsa-miR-522	CLIP-seq
MIRT2108178	hsa-miR-545	CLIP-seq
MIRT2331992	hsa-miR-1266	CLIP-seq
MIRT2108175	hsa-miR-2355-5p	CLIP-seq
MIRT2331993	hsa-miR-3166	CLIP-seq
MIRT2331994	hsa-miR-3178	CLIP-seq
MIRT2331995	hsa-miR-3652	CLIP-seq
MIRT2331996	hsa-miR-3664-3p	CLIP-seq
MIRT2331997	hsa-miR-4430	CLIP-seq
MIRT2331998	hsa-miR-4486	CLIP-seq
MIRT2331999	hsa-miR-4505	CLIP-seq
MIRT2332000	hsa-miR-4518	CLIP-seq
MIRT2332001	hsa-miR-4717-3p	CLIP-seq
MIRT2332002	hsa-miR-4781-5p	CLIP-seq
MIRT2332003	hsa-miR-873	CLIP-seq
MIRT2394788	hsa-miR-329	CLIP-seq
MIRT2394789	hsa-miR-362-3p	CLIP-seq
MIRT2691259	hsa-miR-125a-3p	CLIP-seq
MIRT2691260	hsa-miR-3665	CLIP-seq
MIRT2691261	hsa-miR-4468	CLIP-seq
MIRT2691262	hsa-miR-4690-5p	CLIP-seq
MIRT2691263	hsa-miR-4792	CLIP-seq

Show/Hide all (11)

GO ID	Ontology	Definition	Evidence
GO:0005351	Function	Carbohydrate:proton symporter activity	IEA
GO:0008506	Function	Sucrose:proton symporter activity	IBA
GO:0008506	Function	Sucrose:proton symporter activity	ISS
GO:0015293	Function	Symporter activity	IEA
GO:0015770	Process	Sucrose transport	ISS
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IEA
GO:0034219	Process	Carbohydrate transmembrane transport	IEA
GO:0055085	Process	Transmembrane transport	IEA
GO:1902600	Process	Proton transmembrane transport	IEA

MIM	HGNC	e!Ensembl
619581	29196	ENSG00000022567

Q5BKX6

Protein name

Solute carrier family 45 member 4

Protein function

Proton-associated sucrose transporter. May be able to transport also glucose and fructose.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13347	MFS_2	56 → 274		Family

Sequence

MKMAPQNADPESMQVQELSVPLPDPQKAGGAEAENCETISEGSIDRIPMRLWVMHGAVMF
GREFCYAMETALVTPILLQIGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRR
PFILALCVGVLFGVALFLNGSAIGLALGDVPNRQPIGIVLTVLGVVVLDFSADATEGPIR
AYLLDVVDSEEQDMALNIHAFSAGLGGAIGYVLGGLDWTQTFLGSWFRTQNQVLFFFAAI
IFTVSVALHLFSIDEEQYSPQQERSAEEPGALDGGEPHGVPAFPDEVQSEHELALDYPDV
DIMRSKSDSALHVPDTALDLEPELLFLHDIEPSIFHDASYPATPRSTSQELAKTKLPRLA
TFLKEAAKEDETLLDNHLNEAKVPNGSGSPTKDALGGYTRVDTKPSATSSSMRRRRHAFR
RQASSTFSYYGKLGSHCYRYRRANAVVLIKPSRSMSDLYDMQKRQRQHRHRNQSGATTSS
GDTESEEGEGETTVRLLWLSMLKMPRELMRLCLCHLLTWFSVIAEAVFYTDFMGQVIFEG
DPKAPSNSTAWQAYNAGVKMGCWGLVIYAATGAICSALLQKYLDNYDLSVRVIYVLGTLG
FSVGTAVMAMFPNVYVAMVTISTMGIVSMSISYCPYALLGQYHDIKQYIHHSPGNSKRGF
GIDCAILSCQVYISQILVASALGGVVDAVGTVRVIPMVASVGSFLGFLTATFLVIYPNVS
EEAKEEQKGLSSPLAGEGRAGGNSEKPTVLKLTRKEGLQGPVETESVV

Sequence length

768

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BIPOLAR DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, KNEE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Melanoma	Melanoma	Pubtator	34334114	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

SLC45A4 (solute carrier family 45 member 4)