MFF (mitochondrial fission factor)

Gene

• Entrez ID: 56947
• Gene name: Mitochondrial fission factor
• Gene symbol: MFF
• Synonyms (NCBI Gene): C2orf33, EMPF2, GL004
• Chromosome: 2
• Chromosome location: 2q36.3
• Summary: This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Altern

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs397514615	C>T	Likely-pathogenic, pathogenic	Intron variant, coding sequence variant, stop gained
rs753829320	C>T	Pathogenic	Coding sequence variant, stop gained, non coding transcript variant
rs879255690	AA>-	Pathogenic	Frameshift variant, coding sequence variant, non coding transcript variant
rs886037862	->C	Pathogenic	Coding sequence variant, frameshift variant, intron variant
rs1285225437	C>-	Pathogenic	Frameshift variant, coding sequence variant, non coding transcript variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020583	hsa-miR-155-5p	Proteomics	18668040
MIRT028269	hsa-miR-32-5p	Sequencing	20371350
MIRT054898	hsa-miR-27b-3p	Western blot	25431021
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	20371350
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	20371350
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT459536	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028269	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT459535	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT459534	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT459531	hsa-miR-1279	PAR-CLIP	20371350
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	20371350
MIRT459529	hsa-miR-8064	PAR-CLIP	20371350
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	20371350
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	20371350
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	20371350
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT459536	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028269	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT459535	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT459534	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT459531	hsa-miR-1279	PAR-CLIP	20371350
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	20371350
MIRT459529	hsa-miR-8064	PAR-CLIP	20371350
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	20371350
MIRT545000	hsa-miR-548aa	PAR-CLIP	20371350
MIRT544999	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT544998	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT544997	hsa-miR-3662	PAR-CLIP	20371350
MIRT544996	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT544995	hsa-miR-3646	PAR-CLIP	20371350
MIRT544994	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT544993	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT544992	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT544991	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT544990	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT544989	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT544988	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT544987	hsa-miR-3666	PAR-CLIP	20371350
MIRT544985	hsa-miR-4295	PAR-CLIP	20371350
MIRT544986	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT544984	hsa-miR-1323	PAR-CLIP	20371350
MIRT544983	hsa-miR-548o-3p	PAR-CLIP	20371350
MIRT544982	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT544981	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT544980	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT544979	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT544978	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	20371350
MIRT544977	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT544976	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT544975	hsa-miR-548aw	PAR-CLIP	20371350
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	20371350
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	20371350
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT459536	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028269	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT459535	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT459534	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT459531	hsa-miR-1279	PAR-CLIP	20371350
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	20371350
MIRT459529	hsa-miR-8064	PAR-CLIP	20371350
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	20371350
MIRT545000	hsa-miR-548aa	PAR-CLIP	21572407
MIRT544999	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT544998	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	21572407
MIRT544996	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT544995	hsa-miR-3646	PAR-CLIP	21572407
MIRT544994	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT544993	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT544992	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT544991	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT544990	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT544989	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT544988	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT544987	hsa-miR-3666	PAR-CLIP	21572407
MIRT544985	hsa-miR-4295	PAR-CLIP	21572407
MIRT544986	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT544984	hsa-miR-1323	PAR-CLIP	21572407
MIRT544983	hsa-miR-548o-3p	PAR-CLIP	21572407
MIRT459531	hsa-miR-1279	PAR-CLIP	21572407
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	21572407
MIRT544982	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT544981	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT544980	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT544979	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT544978	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT459529	hsa-miR-8064	PAR-CLIP	21572407
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	21572407
MIRT544977	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT544976	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT544975	hsa-miR-548aw	PAR-CLIP	21572407
MIRT556139	hsa-miR-106a-3p	PAR-CLIP	21572407
MIRT545000	hsa-miR-548aa	PAR-CLIP	21572407
MIRT544999	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT544998	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT544997	hsa-miR-3662	PAR-CLIP	21572407
MIRT544996	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT544995	hsa-miR-3646	PAR-CLIP	21572407
MIRT544994	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT544993	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT544992	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT544991	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT544990	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT544989	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT544988	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT544987	hsa-miR-3666	PAR-CLIP	21572407
MIRT544985	hsa-miR-4295	PAR-CLIP	21572407
MIRT544986	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT544984	hsa-miR-1323	PAR-CLIP	21572407
MIRT544983	hsa-miR-548o-3p	PAR-CLIP	21572407
MIRT544982	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT544981	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT544980	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT544979	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT544978	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	21572407
MIRT544977	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT544976	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT544975	hsa-miR-548aw	PAR-CLIP	21572407
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	23446348
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT459536	hsa-miR-25-3p	PAR-CLIP	23446348
MIRT028269	hsa-miR-32-5p	PAR-CLIP	23446348
MIRT459535	hsa-miR-363-3p	PAR-CLIP	23446348
MIRT459534	hsa-miR-367-3p	PAR-CLIP	23446348
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	23446348
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	23446348
MIRT459531	hsa-miR-1279	PAR-CLIP	23446348
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	23446348
MIRT459529	hsa-miR-8064	PAR-CLIP	23446348
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	23446348
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	23446348
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT459531	hsa-miR-1279	PAR-CLIP	23446348
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	23446348
MIRT459529	hsa-miR-8064	PAR-CLIP	23446348
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	23446348
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	23446348
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT459531	hsa-miR-1279	PAR-CLIP	23446348
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	23446348
MIRT459529	hsa-miR-8064	PAR-CLIP	23446348
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	23446348
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	23592263
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	23592263
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	23592263
MIRT459536	hsa-miR-25-3p	PAR-CLIP	23592263
MIRT028269	hsa-miR-32-5p	PAR-CLIP	23592263
MIRT459535	hsa-miR-363-3p	PAR-CLIP	23592263
MIRT459534	hsa-miR-367-3p	PAR-CLIP	23592263
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	23592263
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	23592263
MIRT459531	hsa-miR-1279	PAR-CLIP	23592263
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	23592263
MIRT459529	hsa-miR-8064	PAR-CLIP	23592263
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	23592263
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	20371350
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	20371350
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT459536	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028269	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT459535	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT459534	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT459531	hsa-miR-1279	PAR-CLIP	20371350
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	20371350
MIRT459529	hsa-miR-8064	PAR-CLIP	20371350
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	20371350
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	20371350
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	20371350
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT459536	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028269	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT459535	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT459534	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT459531	hsa-miR-1279	PAR-CLIP	20371350
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	20371350
MIRT459529	hsa-miR-8064	PAR-CLIP	20371350
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	20371350
MIRT545000	hsa-miR-548aa	PAR-CLIP	20371350
MIRT544999	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT544998	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT544997	hsa-miR-3662	PAR-CLIP	20371350
MIRT544996	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT544995	hsa-miR-3646	PAR-CLIP	20371350
MIRT544994	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT544993	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT544992	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT544991	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT544990	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT544989	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT544988	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT544987	hsa-miR-3666	PAR-CLIP	20371350
MIRT544985	hsa-miR-4295	PAR-CLIP	20371350
MIRT544986	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT544984	hsa-miR-1323	PAR-CLIP	20371350
MIRT544983	hsa-miR-548o-3p	PAR-CLIP	20371350
MIRT544982	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT544981	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT544980	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT544979	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT544978	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	20371350
MIRT544977	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT544976	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT544975	hsa-miR-548aw	PAR-CLIP	20371350
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	20371350
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	20371350
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT459536	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028269	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT459535	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT459534	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT459531	hsa-miR-1279	PAR-CLIP	20371350
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	20371350
MIRT459529	hsa-miR-8064	PAR-CLIP	20371350
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	20371350
MIRT545000	hsa-miR-548aa	PAR-CLIP	21572407
MIRT544999	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT544998	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	21572407
MIRT544996	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT544995	hsa-miR-3646	PAR-CLIP	21572407
MIRT544994	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT544993	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT544992	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT544991	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT544990	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT544989	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT544988	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT544987	hsa-miR-3666	PAR-CLIP	21572407
MIRT544985	hsa-miR-4295	PAR-CLIP	21572407
MIRT544986	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT544984	hsa-miR-1323	PAR-CLIP	21572407
MIRT544983	hsa-miR-548o-3p	PAR-CLIP	21572407
MIRT459531	hsa-miR-1279	PAR-CLIP	21572407
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	21572407
MIRT544982	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT544981	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT544980	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT544979	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT544978	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT459529	hsa-miR-8064	PAR-CLIP	21572407
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	21572407
MIRT544977	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT544976	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT544975	hsa-miR-548aw	PAR-CLIP	21572407
MIRT556139	hsa-miR-106a-3p	PAR-CLIP	21572407
MIRT545000	hsa-miR-548aa	PAR-CLIP	21572407
MIRT544999	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT544998	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT544997	hsa-miR-3662	PAR-CLIP	21572407
MIRT544996	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT544995	hsa-miR-3646	PAR-CLIP	21572407
MIRT544994	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT544993	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT544992	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT544991	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT544990	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT544989	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT544988	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT544987	hsa-miR-3666	PAR-CLIP	21572407
MIRT544985	hsa-miR-4295	PAR-CLIP	21572407
MIRT544986	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT544984	hsa-miR-1323	PAR-CLIP	21572407
MIRT544983	hsa-miR-548o-3p	PAR-CLIP	21572407
MIRT544982	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT544981	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT544980	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT544979	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT544978	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	21572407
MIRT544977	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT544976	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT544975	hsa-miR-548aw	PAR-CLIP	21572407
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	23446348
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT459536	hsa-miR-25-3p	PAR-CLIP	23446348
MIRT028269	hsa-miR-32-5p	PAR-CLIP	23446348
MIRT459535	hsa-miR-363-3p	PAR-CLIP	23446348
MIRT459534	hsa-miR-367-3p	PAR-CLIP	23446348
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	23446348
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	23446348
MIRT459531	hsa-miR-1279	PAR-CLIP	23446348
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	23446348
MIRT459529	hsa-miR-8064	PAR-CLIP	23446348
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	23446348
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	23446348
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT459531	hsa-miR-1279	PAR-CLIP	23446348
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	23446348
MIRT459529	hsa-miR-8064	PAR-CLIP	23446348
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	23446348
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	23446348
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT459531	hsa-miR-1279	PAR-CLIP	23446348
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	23446348
MIRT459529	hsa-miR-8064	PAR-CLIP	23446348
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	23446348
MIRT459539	hsa-miR-548av-3p	PAR-CLIP	23592263
MIRT459538	hsa-miR-4789-3p	PAR-CLIP	23592263
MIRT459537	hsa-miR-5580-3p	PAR-CLIP	23592263
MIRT459536	hsa-miR-25-3p	PAR-CLIP	23592263
MIRT028269	hsa-miR-32-5p	PAR-CLIP	23592263
MIRT459535	hsa-miR-363-3p	PAR-CLIP	23592263
MIRT459534	hsa-miR-367-3p	PAR-CLIP	23592263
MIRT459533	hsa-miR-92a-3p	PAR-CLIP	23592263
MIRT459532	hsa-miR-92b-3p	PAR-CLIP	23592263
MIRT459531	hsa-miR-1279	PAR-CLIP	23592263
MIRT459530	hsa-miR-4738-3p	PAR-CLIP	23592263
MIRT459529	hsa-miR-8064	PAR-CLIP	23592263
MIRT459528	hsa-miR-5589-3p	PAR-CLIP	23592263
MIRT1146071	hsa-miR-1262	CLIP-seq
MIRT1146072	hsa-miR-1267	CLIP-seq
MIRT1146073	hsa-miR-1269	CLIP-seq
MIRT1146074	hsa-miR-1269b	CLIP-seq
MIRT1146075	hsa-miR-1283	CLIP-seq
MIRT1146076	hsa-miR-1288	CLIP-seq
MIRT1146077	hsa-miR-1293	CLIP-seq
MIRT1146078	hsa-miR-1299	CLIP-seq
MIRT1146079	hsa-miR-130a	CLIP-seq
MIRT1146080	hsa-miR-130b	CLIP-seq
MIRT1146081	hsa-miR-139-5p	CLIP-seq
MIRT1146082	hsa-miR-144	CLIP-seq
MIRT1146083	hsa-miR-150	CLIP-seq
MIRT1146084	hsa-miR-1827	CLIP-seq
MIRT1146085	hsa-miR-19a	CLIP-seq
MIRT1146086	hsa-miR-19b	CLIP-seq
MIRT1146087	hsa-miR-2467-3p	CLIP-seq
MIRT1146088	hsa-miR-25	CLIP-seq
MIRT1146089	hsa-miR-301a	CLIP-seq
MIRT1146090	hsa-miR-301b	CLIP-seq
MIRT1146091	hsa-miR-3127-5p	CLIP-seq
MIRT1146092	hsa-miR-3138	CLIP-seq
MIRT1146093	hsa-miR-3163	CLIP-seq
MIRT1146094	hsa-miR-3180-5p	CLIP-seq
MIRT1146095	hsa-miR-32	CLIP-seq
MIRT1146096	hsa-miR-363	CLIP-seq
MIRT1146097	hsa-miR-3667-3p	CLIP-seq
MIRT1146098	hsa-miR-367	CLIP-seq
MIRT1146099	hsa-miR-3672	CLIP-seq
MIRT1146100	hsa-miR-3678-3p	CLIP-seq
MIRT1146101	hsa-miR-3911	CLIP-seq
MIRT1146102	hsa-miR-4259	CLIP-seq
MIRT1146103	hsa-miR-4267	CLIP-seq
MIRT1146104	hsa-miR-4455	CLIP-seq
MIRT1146105	hsa-miR-4483	CLIP-seq
MIRT1146106	hsa-miR-4502	CLIP-seq
MIRT1146107	hsa-miR-450b-5p	CLIP-seq
MIRT1146108	hsa-miR-4515	CLIP-seq
MIRT1146109	hsa-miR-454	CLIP-seq
MIRT1146110	hsa-miR-4645-3p	CLIP-seq
MIRT1146111	hsa-miR-4666-3p	CLIP-seq
MIRT1146112	hsa-miR-4684-5p	CLIP-seq
MIRT1146113	hsa-miR-4691-5p	CLIP-seq
MIRT1146114	hsa-miR-4701-3p	CLIP-seq
MIRT1146115	hsa-miR-4713-5p	CLIP-seq
MIRT1146116	hsa-miR-4740-5p	CLIP-seq
MIRT1146117	hsa-miR-4762-5p	CLIP-seq
MIRT1146118	hsa-miR-4782-5p	CLIP-seq
MIRT1146119	hsa-miR-4800-5p	CLIP-seq
MIRT1146120	hsa-miR-499a-5p	CLIP-seq
MIRT1146121	hsa-miR-516b	CLIP-seq
MIRT1146122	hsa-miR-518a-5p	CLIP-seq
MIRT1146123	hsa-miR-519a	CLIP-seq
MIRT1146124	hsa-miR-527	CLIP-seq
MIRT1146125	hsa-miR-532-3p	CLIP-seq
MIRT1146126	hsa-miR-548o	CLIP-seq
MIRT1146127	hsa-miR-7	CLIP-seq
MIRT1146128	hsa-miR-875-3p	CLIP-seq
MIRT1146129	hsa-miR-92a	CLIP-seq
MIRT1146130	hsa-miR-92b	CLIP-seq
MIRT2041540	hsa-miR-1208	CLIP-seq
MIRT2041541	hsa-miR-141	CLIP-seq
MIRT2041542	hsa-miR-200a	CLIP-seq
MIRT1146091	hsa-miR-3127-5p	CLIP-seq
MIRT1146092	hsa-miR-3138	CLIP-seq
MIRT1146101	hsa-miR-3911	CLIP-seq
MIRT1146104	hsa-miR-4455	CLIP-seq
MIRT2041543	hsa-miR-452	CLIP-seq
MIRT2041544	hsa-miR-4676-3p	CLIP-seq
MIRT1146119	hsa-miR-4800-5p	CLIP-seq
MIRT2041545	hsa-miR-580	CLIP-seq
MIRT2271150	hsa-miR-186	CLIP-seq
MIRT1146088	hsa-miR-25	CLIP-seq
MIRT1146095	hsa-miR-32	CLIP-seq
MIRT1146096	hsa-miR-363	CLIP-seq
MIRT1146098	hsa-miR-367	CLIP-seq
MIRT2271151	hsa-miR-4720-3p	CLIP-seq
MIRT2271152	hsa-miR-4796-5p	CLIP-seq
MIRT2271153	hsa-miR-4804-3p	CLIP-seq
MIRT2271154	hsa-miR-495	CLIP-seq
MIRT2271155	hsa-miR-548a-3p	CLIP-seq
MIRT2271156	hsa-miR-548e	CLIP-seq
MIRT2271157	hsa-miR-548f	CLIP-seq
MIRT1146126	hsa-miR-548o	CLIP-seq
MIRT1146129	hsa-miR-92a	CLIP-seq
MIRT1146130	hsa-miR-92b	CLIP-seq
MIRT2390848	hsa-miR-4765	CLIP-seq
MIRT2390849	hsa-miR-542-3p	CLIP-seq
MIRT1146071	hsa-miR-1262	CLIP-seq
MIRT1146072	hsa-miR-1267	CLIP-seq
MIRT1146073	hsa-miR-1269	CLIP-seq
MIRT1146074	hsa-miR-1269b	CLIP-seq
MIRT1146075	hsa-miR-1283	CLIP-seq
MIRT1146076	hsa-miR-1288	CLIP-seq
MIRT1146077	hsa-miR-1293	CLIP-seq
MIRT1146078	hsa-miR-1299	CLIP-seq
MIRT1146081	hsa-miR-139-5p	CLIP-seq
MIRT1146082	hsa-miR-144	CLIP-seq
MIRT1146083	hsa-miR-150	CLIP-seq
MIRT1146084	hsa-miR-1827	CLIP-seq
MIRT2570273	hsa-miR-2053	CLIP-seq
MIRT1146091	hsa-miR-3127-5p	CLIP-seq
MIRT1146092	hsa-miR-3138	CLIP-seq
MIRT2570274	hsa-miR-3144-3p	CLIP-seq
MIRT1146094	hsa-miR-3180-5p	CLIP-seq
MIRT2570275	hsa-miR-3613-3p	CLIP-seq
MIRT2570276	hsa-miR-3616-5p	CLIP-seq
MIRT2570277	hsa-miR-3647-5p	CLIP-seq
MIRT1146097	hsa-miR-3667-3p	CLIP-seq
MIRT1146099	hsa-miR-3672	CLIP-seq
MIRT2570278	hsa-miR-3682-5p	CLIP-seq
MIRT1146101	hsa-miR-3911	CLIP-seq
MIRT2570279	hsa-miR-409-3p	CLIP-seq
MIRT1146102	hsa-miR-4259	CLIP-seq
MIRT1146103	hsa-miR-4267	CLIP-seq
MIRT2570280	hsa-miR-4427	CLIP-seq
MIRT1146104	hsa-miR-4455	CLIP-seq
MIRT1146105	hsa-miR-4483	CLIP-seq
MIRT1146106	hsa-miR-4502	CLIP-seq
MIRT1146107	hsa-miR-450b-5p	CLIP-seq
MIRT1146108	hsa-miR-4515	CLIP-seq
MIRT1146110	hsa-miR-4645-3p	CLIP-seq
MIRT2570281	hsa-miR-4680-3p	CLIP-seq
MIRT1146112	hsa-miR-4684-5p	CLIP-seq
MIRT1146113	hsa-miR-4691-5p	CLIP-seq
MIRT1146114	hsa-miR-4701-3p	CLIP-seq
MIRT1146115	hsa-miR-4713-5p	CLIP-seq
MIRT1146116	hsa-miR-4740-5p	CLIP-seq
MIRT2570282	hsa-miR-4762-3p	CLIP-seq
MIRT1146117	hsa-miR-4762-5p	CLIP-seq
MIRT1146118	hsa-miR-4782-5p	CLIP-seq
MIRT2570283	hsa-miR-4795-5p	CLIP-seq
MIRT2271152	hsa-miR-4796-5p	CLIP-seq
MIRT1146119	hsa-miR-4800-5p	CLIP-seq
MIRT2570284	hsa-miR-488	CLIP-seq
MIRT1146120	hsa-miR-499a-5p	CLIP-seq
MIRT1146121	hsa-miR-516b	CLIP-seq
MIRT1146122	hsa-miR-518a-5p	CLIP-seq
MIRT1146124	hsa-miR-527	CLIP-seq
MIRT1146125	hsa-miR-532-3p	CLIP-seq
MIRT2271155	hsa-miR-548a-3p	CLIP-seq
MIRT2271156	hsa-miR-548e	CLIP-seq
MIRT2271157	hsa-miR-548f	CLIP-seq
MIRT1146126	hsa-miR-548o	CLIP-seq
MIRT2570285	hsa-miR-569	CLIP-seq
MIRT2570286	hsa-miR-573	CLIP-seq
MIRT2570287	hsa-miR-591	CLIP-seq
MIRT2570288	hsa-miR-653	CLIP-seq
MIRT1146127	hsa-miR-7	CLIP-seq
MIRT1146128	hsa-miR-875-3p	CLIP-seq
MIRT2570289	hsa-miR-875-5p	CLIP-seq
MIRT1146071	hsa-miR-1262	CLIP-seq
MIRT1146073	hsa-miR-1269	CLIP-seq
MIRT1146074	hsa-miR-1269b	CLIP-seq
MIRT1146075	hsa-miR-1283	CLIP-seq
MIRT1146076	hsa-miR-1288	CLIP-seq
MIRT1146077	hsa-miR-1293	CLIP-seq
MIRT1146078	hsa-miR-1299	CLIP-seq
MIRT1146081	hsa-miR-139-5p	CLIP-seq
MIRT1146083	hsa-miR-150	CLIP-seq
MIRT2684937	hsa-miR-154	CLIP-seq
MIRT1146084	hsa-miR-1827	CLIP-seq
MIRT2570273	hsa-miR-2053	CLIP-seq
MIRT1146091	hsa-miR-3127-5p	CLIP-seq
MIRT1146092	hsa-miR-3138	CLIP-seq
MIRT2570274	hsa-miR-3144-3p	CLIP-seq
MIRT2684938	hsa-miR-3185	CLIP-seq
MIRT2570275	hsa-miR-3613-3p	CLIP-seq
MIRT2570276	hsa-miR-3616-5p	CLIP-seq
MIRT2570277	hsa-miR-3647-5p	CLIP-seq
MIRT1146097	hsa-miR-3667-3p	CLIP-seq
MIRT2570278	hsa-miR-3682-5p	CLIP-seq
MIRT1146101	hsa-miR-3911	CLIP-seq
MIRT2570279	hsa-miR-409-3p	CLIP-seq
MIRT1146102	hsa-miR-4259	CLIP-seq
MIRT2570280	hsa-miR-4427	CLIP-seq
MIRT1146104	hsa-miR-4455	CLIP-seq
MIRT1146105	hsa-miR-4483	CLIP-seq
MIRT1146106	hsa-miR-4502	CLIP-seq
MIRT1146107	hsa-miR-450b-5p	CLIP-seq
MIRT1146108	hsa-miR-4515	CLIP-seq
MIRT2570281	hsa-miR-4680-3p	CLIP-seq
MIRT1146112	hsa-miR-4684-5p	CLIP-seq
MIRT1146113	hsa-miR-4691-5p	CLIP-seq
MIRT1146114	hsa-miR-4701-3p	CLIP-seq
MIRT1146115	hsa-miR-4713-5p	CLIP-seq
MIRT1146116	hsa-miR-4740-5p	CLIP-seq
MIRT2570282	hsa-miR-4762-3p	CLIP-seq
MIRT1146117	hsa-miR-4762-5p	CLIP-seq
MIRT1146118	hsa-miR-4782-5p	CLIP-seq
MIRT2570283	hsa-miR-4795-5p	CLIP-seq
MIRT1146119	hsa-miR-4800-5p	CLIP-seq
MIRT2570284	hsa-miR-488	CLIP-seq
MIRT1146120	hsa-miR-499a-5p	CLIP-seq
MIRT1146121	hsa-miR-516b	CLIP-seq
MIRT1146122	hsa-miR-518a-5p	CLIP-seq
MIRT1146124	hsa-miR-527	CLIP-seq
MIRT1146125	hsa-miR-532-3p	CLIP-seq
MIRT2271155	hsa-miR-548a-3p	CLIP-seq
MIRT2271156	hsa-miR-548e	CLIP-seq
MIRT2271157	hsa-miR-548f	CLIP-seq
MIRT1146126	hsa-miR-548o	CLIP-seq
MIRT2570285	hsa-miR-569	CLIP-seq
MIRT2570286	hsa-miR-573	CLIP-seq
MIRT2570287	hsa-miR-591	CLIP-seq
MIRT2570288	hsa-miR-653	CLIP-seq
MIRT1146127	hsa-miR-7	CLIP-seq
MIRT1146128	hsa-miR-875-3p	CLIP-seq
MIRT2570289	hsa-miR-875-5p	CLIP-seq
MIRT2684939	hsa-miR-876-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000266	Process	Mitochondrial fission	IDA	23283981, 23530241
GO:0000266	Process	Mitochondrial fission	IEA
GO:0000266	Process	Mitochondrial fission	IMP	18353969, 21149567
GO:0000266	Process	Mitochondrial fission	ISS
GO:0005515	Function	Protein binding	IPI	21149567, 26358295, 29464060, 32296183, 36217029
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IBA
GO:0005741	Component	Mitochondrial outer membrane	IDA	21149567
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005777	Component	Peroxisome	IBA
GO:0005777	Component	Peroxisome	IDA	18353969, 23921378
GO:0005777	Component	Peroxisome	IEA
GO:0006626	Process	Protein targeting to mitochondrion	IBA
GO:0006626	Process	Protein targeting to mitochondrion	IDA	23283981
GO:0006626	Process	Protein targeting to mitochondrion	IEA
GO:0006626	Process	Protein targeting to mitochondrion	IMP	21149567
GO:0006626	Process	Protein targeting to mitochondrion	ISS
GO:0007005	Process	Mitochondrion organization	IMP	21149567
GO:0008021	Component	Synaptic vesicle	IEA
GO:0016020	Component	Membrane	IEA
GO:0016559	Process	Peroxisome fission	IMP	18353969, 21149567
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031966	Component	Mitochondrial membrane	IDA	18353969
GO:0032991	Component	Protein-containing complex	IDA	18353969
GO:0042802	Function	Identical protein binding	IPI	18353969, 32296183
GO:0042803	Function	Protein homodimerization activity	IDA	23530241
GO:0045202	Component	Synapse	IEA
GO:0090141	Process	Positive regulation of mitochondrial fission	IBA

Other IDs

• MIM: 614785
• HGNC: 24858
• e!Ensembl: ENSG00000168958

Protein

• UniProt ID: Q9GZY8
• Protein name: Mitochondrial fission factor
• Protein function: Plays a role in mitochondrial and peroxisomal fission (PubMed:18353969, PubMed:23530241, PubMed:24196833). Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (PubMed:23
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05644	Miff	27 → 342	Mitochondrial and peroxisomal fission factor Mff	Family

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in heart, kidney, liver, brain, muscle, and stomach. {ECO:0000269|PubMed:18353969}.
• Sequence:

  MSKGTSSDTSLGRVSRAAFPSPTAAEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNA
  DLEQGFQEGVPNASVIMQVPERIVVAGNNEDVSFSRPADLDLIQSTPFKPLALKTPPRVL
  TLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSLWHRSDSA
  PRNKISRFQAPISAPEYTVTPSPQQARVCPPHMLPEDGANLSSARGILSLIQSSTRRAYQ
  QILDVLDENRRPVLRGGSAAATSNPHHDNVRYGISNIDTTIEGTSDDLTVVDAASLRRQI
  IKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR

• Sequence length: 342

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Encephalopathy due to defective mitochondrial and peroxisomal fission 2	Likely pathogenic; Pathogenic	rs747892565, rs886037862, rs753829320, rs879255690, rs868706737, rs397514615, rs1285225437, rs2075318017	RCV003990956 RCV000239691 RCV000239619 RCV000239645 RCV003990947 RCV000033052 RCV000656526 RCV001290306	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Global developmental delay	Likely pathogenic; Pathogenic	rs397514615	RCV000162157	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Mitochondrial encephalomyopathy	Likely pathogenic; Pathogenic	rs397514615	RCV000162157	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
EXOSTOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LEIGH SYNDROME	—	ClinGen, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MFF-related disorder	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Microcephaly	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL ENCEPHALOMYOPATHIES	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Papillary renal cell carcinoma type 1	-	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENTRICULAR DYSFUNCTION, LEFT	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	31582380		★☆☆☆☆ Found in Text Mining only
Astigmatism	Astigmatism	GWASCAT_DG	30306274		★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	30339249		★☆☆☆☆ Found in Text Mining only
Basal Ganglia Diseases	Basal Ganglia Diseases	BEFREE	26783368		★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	35538029	Associate	★☆☆☆☆ Found in Text Mining only
Cerebellar atrophy	Cerebellar atrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Deglutition Disorders	Dysphagia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Encephalopathies	Epileptic encephalopathy	BEFREE	26783368, 30581454		★☆☆☆☆ Found in Text Mining only
ENCEPHALOPATHY DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION 2	Encephalopathy	ORPHANET_DG	22499341, 26783368		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ENCEPHALOPATHY DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION 2	Encephalopathy	GENOMICS_ENGLAND_DG	22499341, 27604308		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ENCEPHALOPATHY DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION 2	Encephalopathy	CTD_human_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ENCEPHALOPATHY DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION 2	Encephalopathy	CLINVAR_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Epileptic encephalopathy	Epileptic encephalopathy	BEFREE	30581454		★☆☆☆☆ Found in Text Mining only
External Ophthalmoplegia	External Ophthalmoplegia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	CLINVAR_DG			★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Global developmental delay	Developmental Delay	HPO_DG			★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Hypoxia	Hypoxia	Pubtator	35042949	Stimulate	★☆☆☆☆ Found in Text Mining only
Iron Overload	Iron Overload	BEFREE	29725013		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	29496454		★☆☆☆☆ Found in Text Mining only
Lung Diseases	Lung disease	Pubtator	35042949	Associate	★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	31542392, 31582380		★☆☆☆☆ Found in Text Mining only
MFF-related encephalopathy due to mitochondrial and peroxisomal fission defect	Encephalopathy	Orphanet			★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	HPO_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mitochondrial Diseases	Mitochondrial disease	Pubtator	22878233	Stimulate	★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Mitochondrial Diseases	BEFREE	30581454		★☆☆☆☆ Found in Text Mining only
Mitochondrial Encephalomyopathies	Mitochondrial encephalomyopathy	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	29725013		★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	29725013	Associate	★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	CTD_human_DG	23867156		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neoplasms	Neoplasms	BEFREE	31582380		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	26008206	Associate	★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	31582380		★☆☆☆☆ Found in Text Mining only
Optic Atrophy	Optic Atrophy	BEFREE	28131082		★☆☆☆☆ Found in Text Mining only
Optic Atrophy	Optic Atrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Optic Atrophy 1	Optic Atrophy	BEFREE	28683400, 29993201, 31032918		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	37291333	Associate	★☆☆☆☆ Found in Text Mining only
Peripheral Nervous System Diseases	Nervous System Diseases	BEFREE	26783368		★☆☆☆☆ Found in Text Mining only
Peripheral Nervous System Diseases	Nervous System Diseases	HPO_DG			★☆☆☆☆ Found in Text Mining only
Peripheral Neuropathy	Peripheral Neuropathy	BEFREE	26783368		★☆☆☆☆ Found in Text Mining only
Pulmonary Arterial Hypertension	Pulmonary arterial hypertension	Pubtator	35042949	Associate	★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	38110986	Associate	★☆☆☆☆ Found in Text Mining only
Sjogren's Syndrome	Sjogren syndrome	Pubtator	35359935	Associate	★☆☆☆☆ Found in Text Mining only
Sleep Deprivation	Sleep deprivation	Pubtator	22878233	Stimulate	★☆☆☆☆ Found in Text Mining only
Sleep Deprivation	Sleep deprivation	Pubtator	24176854, 29725013	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of tongue	Tongue carcinoma	BEFREE	25912308		★☆☆☆☆ Found in Text Mining only
Vascular Diseases	Vascular disease	Pubtator	33763168	Associate	★☆☆☆☆ Found in Text Mining only