Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	56902
Gene name	Partner of NOB1 homolog
Gene symbol	PNO1
Synonyms (NCBI Gene)	KHRBP1RRP20
Chromosome	2
Chromosome location	2p14

332

Show/Hide all (332)

miRTarBase ID	miRNA	Experiments	Reference
MIRT700732	hsa-miR-510-5p	HITS-CLIP	23313552
MIRT700731	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT700730	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT700729	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT700728	hsa-miR-25-3p	HITS-CLIP	23313552
MIRT700727	hsa-miR-32-5p	HITS-CLIP	23313552
MIRT700726	hsa-miR-363-3p	HITS-CLIP	23313552
MIRT700725	hsa-miR-367-3p	HITS-CLIP	23313552
MIRT700724	hsa-miR-92a-3p	HITS-CLIP	23313552
MIRT700723	hsa-miR-92b-3p	HITS-CLIP	23313552
MIRT700722	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT700721	hsa-miR-4459	HITS-CLIP	23313552
MIRT700720	hsa-miR-4433a-3p	HITS-CLIP	23313552
MIRT700719	hsa-miR-3664-3p	HITS-CLIP	23313552
MIRT700718	hsa-miR-17-3p	HITS-CLIP	23313552
MIRT700716	hsa-miR-5186	HITS-CLIP	23313552
MIRT700717	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT700715	hsa-miR-558	HITS-CLIP	23313552
MIRT700713	hsa-miR-4487	HITS-CLIP	23313552
MIRT700714	hsa-miR-1827	HITS-CLIP	23313552
MIRT700712	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT700711	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT700710	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT700709	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT700708	hsa-miR-3612	HITS-CLIP	23313552
MIRT700707	hsa-miR-650	HITS-CLIP	23313552
MIRT700706	hsa-miR-500a-3p	HITS-CLIP	23313552
MIRT636317	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT636316	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT636315	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT636314	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT636312	hsa-miR-1305	HITS-CLIP	23824327
MIRT636317	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT636316	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT654950	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT636315	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT636314	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT636312	hsa-miR-1305	HITS-CLIP	23824327
MIRT654949	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT636317	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT636316	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT636315	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT636314	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT636313	hsa-miR-607	HITS-CLIP	23824327
MIRT636312	hsa-miR-1305	HITS-CLIP	23824327
MIRT159778	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT159778	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT700732	hsa-miR-510-5p	HITS-CLIP	23313552
MIRT700731	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT700730	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT700729	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT700728	hsa-miR-25-3p	HITS-CLIP	23313552
MIRT700727	hsa-miR-32-5p	HITS-CLIP	23313552
MIRT700726	hsa-miR-363-3p	HITS-CLIP	23313552
MIRT700725	hsa-miR-367-3p	HITS-CLIP	23313552
MIRT700724	hsa-miR-92a-3p	HITS-CLIP	23313552
MIRT700723	hsa-miR-92b-3p	HITS-CLIP	23313552
MIRT700722	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT700721	hsa-miR-4459	HITS-CLIP	23313552
MIRT700720	hsa-miR-4433a-3p	HITS-CLIP	23313552
MIRT700719	hsa-miR-3664-3p	HITS-CLIP	23313552
MIRT700718	hsa-miR-17-3p	HITS-CLIP	23313552
MIRT700716	hsa-miR-5186	HITS-CLIP	23313552
MIRT700717	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT700715	hsa-miR-558	HITS-CLIP	23313552
MIRT700713	hsa-miR-4487	HITS-CLIP	23313552
MIRT700714	hsa-miR-1827	HITS-CLIP	23313552
MIRT700712	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT700711	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT700710	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT700709	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT700708	hsa-miR-3612	HITS-CLIP	23313552
MIRT700707	hsa-miR-650	HITS-CLIP	23313552
MIRT700706	hsa-miR-500a-3p	HITS-CLIP	23313552
MIRT636317	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT636316	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT636315	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT636314	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT636312	hsa-miR-1305	HITS-CLIP	23824327
MIRT636317	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT636316	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT654950	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT636315	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT636314	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT636312	hsa-miR-1305	HITS-CLIP	23824327
MIRT654949	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT636317	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT636316	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT636315	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT636314	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT636313	hsa-miR-607	HITS-CLIP	23824327
MIRT636312	hsa-miR-1305	HITS-CLIP	23824327
MIRT1245241	hsa-miR-1183	CLIP-seq
MIRT1245242	hsa-miR-1207-3p	CLIP-seq
MIRT1245243	hsa-miR-1226	CLIP-seq
MIRT1245244	hsa-miR-1233	CLIP-seq
MIRT1245245	hsa-miR-1283	CLIP-seq
MIRT1245246	hsa-miR-129-3p	CLIP-seq
MIRT1245247	hsa-miR-184	CLIP-seq
MIRT1245248	hsa-miR-197	CLIP-seq
MIRT1245249	hsa-miR-2114	CLIP-seq
MIRT1245250	hsa-miR-2276	CLIP-seq
MIRT1245251	hsa-miR-31	CLIP-seq
MIRT1245252	hsa-miR-3149	CLIP-seq
MIRT1245253	hsa-miR-3154	CLIP-seq
MIRT1245254	hsa-miR-3171	CLIP-seq
MIRT1245255	hsa-miR-3185	CLIP-seq
MIRT1245256	hsa-miR-3188	CLIP-seq
MIRT1245257	hsa-miR-323-5p	CLIP-seq
MIRT1245258	hsa-miR-3607-3p	CLIP-seq
MIRT1245259	hsa-miR-3622b-5p	CLIP-seq
MIRT1245260	hsa-miR-3670	CLIP-seq
MIRT1245261	hsa-miR-3671	CLIP-seq
MIRT1245262	hsa-miR-3675-3p	CLIP-seq
MIRT1245263	hsa-miR-369-3p	CLIP-seq
MIRT1245264	hsa-miR-371-5p	CLIP-seq
MIRT1245265	hsa-miR-371b-5p	CLIP-seq
MIRT1245266	hsa-miR-374a	CLIP-seq
MIRT1245267	hsa-miR-374b	CLIP-seq
MIRT1245268	hsa-miR-377	CLIP-seq
MIRT1245269	hsa-miR-3926	CLIP-seq
MIRT1245270	hsa-miR-4255	CLIP-seq
MIRT1245271	hsa-miR-4433	CLIP-seq
MIRT1245272	hsa-miR-4475	CLIP-seq
MIRT1245273	hsa-miR-4477b	CLIP-seq
MIRT1245274	hsa-miR-4645-5p	CLIP-seq
MIRT1245275	hsa-miR-4662a-5p	CLIP-seq
MIRT1245276	hsa-miR-4673	CLIP-seq
MIRT1245277	hsa-miR-4676-5p	CLIP-seq
MIRT1245278	hsa-miR-4684-5p	CLIP-seq
MIRT1245279	hsa-miR-4696	CLIP-seq
MIRT1245280	hsa-miR-4733-3p	CLIP-seq
MIRT1245281	hsa-miR-4738-3p	CLIP-seq
MIRT1245282	hsa-miR-4755-3p	CLIP-seq
MIRT1245283	hsa-miR-505	CLIP-seq
MIRT1245284	hsa-miR-5096	CLIP-seq
MIRT1245285	hsa-miR-548a-5p	CLIP-seq
MIRT1245286	hsa-miR-548aa	CLIP-seq
MIRT1245287	hsa-miR-548ab	CLIP-seq
MIRT1245288	hsa-miR-548ak	CLIP-seq
MIRT1245289	hsa-miR-548an	CLIP-seq
MIRT1245290	hsa-miR-548b-5p	CLIP-seq
MIRT1245291	hsa-miR-548c-5p	CLIP-seq
MIRT1245292	hsa-miR-548d-5p	CLIP-seq
MIRT1245293	hsa-miR-548h	CLIP-seq
MIRT1245294	hsa-miR-548i	CLIP-seq
MIRT1245295	hsa-miR-548j	CLIP-seq
MIRT1245296	hsa-miR-548k	CLIP-seq
MIRT1245297	hsa-miR-548l	CLIP-seq
MIRT1245298	hsa-miR-548s	CLIP-seq
MIRT1245299	hsa-miR-548w	CLIP-seq
MIRT1245300	hsa-miR-548y	CLIP-seq
MIRT1245301	hsa-miR-550b	CLIP-seq
MIRT1245302	hsa-miR-556-5p	CLIP-seq
MIRT1245303	hsa-miR-559	CLIP-seq
MIRT1245304	hsa-miR-575	CLIP-seq
MIRT1245305	hsa-miR-577	CLIP-seq
MIRT1245306	hsa-miR-578	CLIP-seq
MIRT1245307	hsa-miR-580	CLIP-seq
MIRT1245308	hsa-miR-581	CLIP-seq
MIRT1245309	hsa-miR-665	CLIP-seq
MIRT1245310	hsa-miR-7	CLIP-seq
MIRT1245311	hsa-miR-758	CLIP-seq
MIRT1245312	hsa-miR-876-3p	CLIP-seq
MIRT1245243	hsa-miR-1226	CLIP-seq
MIRT2072566	hsa-miR-1251	CLIP-seq
MIRT2072567	hsa-miR-1262	CLIP-seq
MIRT2072568	hsa-miR-1304	CLIP-seq
MIRT2072569	hsa-miR-1321	CLIP-seq
MIRT2072570	hsa-miR-188-5p	CLIP-seq
MIRT1245248	hsa-miR-197	CLIP-seq
MIRT1245249	hsa-miR-2114	CLIP-seq
MIRT2072571	hsa-miR-25	CLIP-seq
MIRT1245251	hsa-miR-31	CLIP-seq
MIRT2072572	hsa-miR-3162-5p	CLIP-seq
MIRT2072573	hsa-miR-32	CLIP-seq
MIRT2072574	hsa-miR-363	CLIP-seq
MIRT2072575	hsa-miR-3646	CLIP-seq
MIRT2072576	hsa-miR-367	CLIP-seq
MIRT2072577	hsa-miR-3942-3p	CLIP-seq
MIRT2072578	hsa-miR-4293	CLIP-seq
MIRT1245271	hsa-miR-4433	CLIP-seq
MIRT2072579	hsa-miR-4504	CLIP-seq
MIRT2072580	hsa-miR-4633-5p	CLIP-seq
MIRT2072581	hsa-miR-4701-3p	CLIP-seq
MIRT1245280	hsa-miR-4733-3p	CLIP-seq
MIRT2072582	hsa-miR-4739	CLIP-seq
MIRT2072583	hsa-miR-4756-5p	CLIP-seq
MIRT2072584	hsa-miR-4780	CLIP-seq
MIRT2072585	hsa-miR-4793-3p	CLIP-seq
MIRT1245284	hsa-miR-5096	CLIP-seq
MIRT2072586	hsa-miR-532-5p	CLIP-seq
MIRT1245289	hsa-miR-548an	CLIP-seq
MIRT1245297	hsa-miR-548l	CLIP-seq
MIRT1245305	hsa-miR-577	CLIP-seq
MIRT2072587	hsa-miR-596	CLIP-seq
MIRT2072588	hsa-miR-623	CLIP-seq
MIRT2072589	hsa-miR-661	CLIP-seq
MIRT1245309	hsa-miR-665	CLIP-seq
MIRT2072590	hsa-miR-767-5p	CLIP-seq
MIRT2072591	hsa-miR-92a	CLIP-seq
MIRT2072592	hsa-miR-92b	CLIP-seq
MIRT2072566	hsa-miR-1251	CLIP-seq
MIRT2072567	hsa-miR-1262	CLIP-seq
MIRT2072568	hsa-miR-1304	CLIP-seq
MIRT2072569	hsa-miR-1321	CLIP-seq
MIRT1245249	hsa-miR-2114	CLIP-seq
MIRT2072571	hsa-miR-25	CLIP-seq
MIRT2299683	hsa-miR-3159	CLIP-seq
MIRT2072572	hsa-miR-3162-5p	CLIP-seq
MIRT1245254	hsa-miR-3171	CLIP-seq
MIRT2072573	hsa-miR-32	CLIP-seq
MIRT2299684	hsa-miR-3545-3p	CLIP-seq
MIRT2299685	hsa-miR-3614-5p	CLIP-seq
MIRT2072574	hsa-miR-363	CLIP-seq
MIRT2072576	hsa-miR-367	CLIP-seq
MIRT1245260	hsa-miR-3670	CLIP-seq
MIRT1245263	hsa-miR-369-3p	CLIP-seq
MIRT1245266	hsa-miR-374a	CLIP-seq
MIRT1245267	hsa-miR-374b	CLIP-seq
MIRT2299686	hsa-miR-3929	CLIP-seq
MIRT2072578	hsa-miR-4293	CLIP-seq
MIRT2299687	hsa-miR-4419b	CLIP-seq
MIRT1245271	hsa-miR-4433	CLIP-seq
MIRT2299688	hsa-miR-4478	CLIP-seq
MIRT2072579	hsa-miR-4504	CLIP-seq
MIRT2299689	hsa-miR-4680-5p	CLIP-seq
MIRT2299690	hsa-miR-4686	CLIP-seq
MIRT2072581	hsa-miR-4701-3p	CLIP-seq
MIRT2299691	hsa-miR-4722-5p	CLIP-seq
MIRT1245281	hsa-miR-4738-3p	CLIP-seq
MIRT2072582	hsa-miR-4739	CLIP-seq
MIRT2072583	hsa-miR-4756-5p	CLIP-seq
MIRT2072584	hsa-miR-4780	CLIP-seq
MIRT2072585	hsa-miR-4793-3p	CLIP-seq
MIRT1245283	hsa-miR-505	CLIP-seq
MIRT1245301	hsa-miR-550b	CLIP-seq
MIRT1245302	hsa-miR-556-5p	CLIP-seq
MIRT1245305	hsa-miR-577	CLIP-seq
MIRT2072587	hsa-miR-596	CLIP-seq
MIRT2072588	hsa-miR-623	CLIP-seq
MIRT2072589	hsa-miR-661	CLIP-seq
MIRT1245309	hsa-miR-665	CLIP-seq
MIRT2072590	hsa-miR-767-5p	CLIP-seq
MIRT2072591	hsa-miR-92a	CLIP-seq
MIRT2072592	hsa-miR-92b	CLIP-seq
MIRT2456784	hsa-miR-127-3p	CLIP-seq
MIRT1245247	hsa-miR-184	CLIP-seq
MIRT2456785	hsa-miR-3122	CLIP-seq
MIRT2456786	hsa-miR-3197	CLIP-seq
MIRT2456787	hsa-miR-3689a-3p	CLIP-seq
MIRT2456788	hsa-miR-3689c	CLIP-seq
MIRT2456789	hsa-miR-3913-5p	CLIP-seq
MIRT2299686	hsa-miR-3929	CLIP-seq
MIRT2299687	hsa-miR-4419b	CLIP-seq
MIRT2299688	hsa-miR-4478	CLIP-seq
MIRT2072580	hsa-miR-4633-5p	CLIP-seq
MIRT2456790	hsa-miR-4649-3p	CLIP-seq
MIRT2456791	hsa-miR-4728-5p	CLIP-seq
MIRT1245283	hsa-miR-505	CLIP-seq
MIRT2072586	hsa-miR-532-5p	CLIP-seq
MIRT2596424	hsa-miR-1273d	CLIP-seq
MIRT2596425	hsa-miR-128	CLIP-seq
MIRT1245245	hsa-miR-1283	CLIP-seq
MIRT1245247	hsa-miR-184	CLIP-seq
MIRT1245249	hsa-miR-2114	CLIP-seq
MIRT2596426	hsa-miR-27a	CLIP-seq
MIRT2596427	hsa-miR-27b	CLIP-seq
MIRT2456785	hsa-miR-3122	CLIP-seq
MIRT2596428	hsa-miR-3126-3p	CLIP-seq
MIRT2456786	hsa-miR-3197	CLIP-seq
MIRT1245262	hsa-miR-3675-3p	CLIP-seq
MIRT2456787	hsa-miR-3689a-3p	CLIP-seq
MIRT2456788	hsa-miR-3689c	CLIP-seq
MIRT2596429	hsa-miR-378	CLIP-seq
MIRT2596430	hsa-miR-378b	CLIP-seq
MIRT2596431	hsa-miR-378c	CLIP-seq
MIRT2596432	hsa-miR-378d	CLIP-seq
MIRT2596433	hsa-miR-378e	CLIP-seq
MIRT2596434	hsa-miR-378f	CLIP-seq
MIRT2596435	hsa-miR-378h	CLIP-seq
MIRT2596436	hsa-miR-378i	CLIP-seq
MIRT2596437	hsa-miR-382	CLIP-seq
MIRT2456789	hsa-miR-3913-5p	CLIP-seq
MIRT2299686	hsa-miR-3929	CLIP-seq
MIRT2596438	hsa-miR-422a	CLIP-seq
MIRT2596439	hsa-miR-4417	CLIP-seq
MIRT2299687	hsa-miR-4419b	CLIP-seq
MIRT2299688	hsa-miR-4478	CLIP-seq
MIRT2596440	hsa-miR-4535	CLIP-seq
MIRT2596441	hsa-miR-4638-3p	CLIP-seq
MIRT2456790	hsa-miR-4649-3p	CLIP-seq
MIRT1245278	hsa-miR-4684-5p	CLIP-seq
MIRT2456791	hsa-miR-4728-5p	CLIP-seq
MIRT2596442	hsa-miR-492	CLIP-seq
MIRT1245283	hsa-miR-505	CLIP-seq
MIRT2072566	hsa-miR-1251	CLIP-seq
MIRT2688286	hsa-miR-1253	CLIP-seq
MIRT2072567	hsa-miR-1262	CLIP-seq
MIRT2596424	hsa-miR-1273d	CLIP-seq
MIRT2596425	hsa-miR-128	CLIP-seq
MIRT1245245	hsa-miR-1283	CLIP-seq
MIRT2596426	hsa-miR-27a	CLIP-seq
MIRT2596427	hsa-miR-27b	CLIP-seq
MIRT2596428	hsa-miR-3126-3p	CLIP-seq
MIRT1245262	hsa-miR-3675-3p	CLIP-seq
MIRT2596429	hsa-miR-378	CLIP-seq
MIRT2596430	hsa-miR-378b	CLIP-seq
MIRT2596431	hsa-miR-378c	CLIP-seq
MIRT2596432	hsa-miR-378d	CLIP-seq
MIRT2596433	hsa-miR-378e	CLIP-seq
MIRT2596434	hsa-miR-378f	CLIP-seq
MIRT2596435	hsa-miR-378h	CLIP-seq
MIRT2596436	hsa-miR-378i	CLIP-seq
MIRT2596437	hsa-miR-382	CLIP-seq
MIRT2596438	hsa-miR-422a	CLIP-seq
MIRT2072578	hsa-miR-4293	CLIP-seq
MIRT2596439	hsa-miR-4417	CLIP-seq
MIRT2596440	hsa-miR-4535	CLIP-seq
MIRT2596441	hsa-miR-4638-3p	CLIP-seq
MIRT2299689	hsa-miR-4680-5p	CLIP-seq
MIRT1245278	hsa-miR-4684-5p	CLIP-seq
MIRT2072581	hsa-miR-4701-3p	CLIP-seq
MIRT2688287	hsa-miR-4742-3p	CLIP-seq
MIRT2072585	hsa-miR-4793-3p	CLIP-seq
MIRT2596442	hsa-miR-492	CLIP-seq
MIRT1245283	hsa-miR-505	CLIP-seq
MIRT2688288	hsa-miR-510	CLIP-seq
MIRT1245307	hsa-miR-580	CLIP-seq
MIRT2072587	hsa-miR-596	CLIP-seq
MIRT2072589	hsa-miR-661	CLIP-seq
MIRT2072590	hsa-miR-767-5p	CLIP-seq

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	28514442, 32296183, 32814053, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA	15497447
GO:0005730	Component	Nucleolus	IEA
GO:0005829	Component	Cytosol	TAS
GO:0032040	Component	Small-subunit processome	IDA	34516797
GO:0042274	Process	Ribosomal small subunit biogenesis	IDA	34516797

MIM	HGNC	e!Ensembl
618710	32790	ENSG00000115946

Q9NRX1

Protein name

RNA-binding protein PNO1 (Partner of NOB1)

Protein function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associat

PDB

6G18 , 6G4S , 6G4W , 6G51 , 6G53 , 6G5I , 6ZUO , 6ZXD , 6ZXE , 7MQ8 , 7MQ9 , 7MQA , 7WTS , 7WTT , 7WTU , 7WTV , 7WTW , 7WTX , 7WTZ , 7WU0 , 8ZDC , 8ZDD

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Expressed in liver, lung, spleen and kidney. Weakly expressed in thymus, testis and ovary. Weakly or not expressed in heart, brain, skeletal muscle, placenta, pancreas, prostate, small intestine, colon and peripheral blood leukocytes.

Sequence

MESEMETQSARAEEGFTQVTRKGGRRAKKRQAEQLSAAGEGGDAGRMDTEEARPAKRPVF
PPLCGDGLLSGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRT
CKETKDVSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAI
GRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGN
IRAVASRSADRF

Sequence length

252

Interactions

View interactions

	Reactome
			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of urinary bladder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (73)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	19781077, 19833869, 20133711, 22055719, 22957047, 23042786, 24262168, 24840975, 24899262, 24920338, 25239623, 25429138, 26330466, 26895297, 28549443 View all (6 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis, Familial	Amyotrophic lateral sclerosis	BEFREE	19781077		★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis, Sporadic	Lateral Sclerosis	BEFREE	23046583		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	30340104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	30340104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	19728080, 24840202		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	14562043		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	34050137	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	31800162		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	12644826, 15205328, 24722255, 28038443, 30862720		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	20727170, 26717985, 31462944		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathy, Familial Idiopathic	Cardiomyopathy	BEFREE	24960161		★★★★★ ★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	25362645		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	25362645		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic heart failure	Heart Failure	BEFREE	24960161		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cockayne Syndrome, Type I	Cockayne Syndrome	BEFREE	30045422		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	19686745		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	30862720, 31064870		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	24960161		★★★★★ ★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	20219773		★★★★★ ★☆☆☆☆ Found in Text Mining only
Delirium, Dementia, Amnestic, Cognitive Disorders	Delirium, Dementia, Amnestic, Cognitive Disorders	BEFREE	24103357		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathy	Diabetic Nephropathy	BEFREE	25528059		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	BEFREE	28724967		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	20727170		★★★★★ ★☆☆☆☆ Found in Text Mining only
Essential Tremor	Tremor	BEFREE	24840975		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fragile X Syndrome	Fragile X Syndrome	BEFREE	12594214, 21900387, 24462888		★★★★★ ★☆☆☆☆ Found in Text Mining only
Frontotemporal dementia	Frontotemporal dementia	BEFREE	19781077, 23042786, 28663553		★★★★★ ★☆☆☆☆ Found in Text Mining only
Frontotemporal Lobar Degeneration	Frontotemporal dementia	BEFREE	18223198, 19833869, 20133711, 22957047, 24840975, 26895297		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	26100017		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	26100017		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	26933087, 28790173		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hamman-Rich syndrome	Hamman-Rich syndrome	BEFREE	30665514		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kaposi Sarcoma	Kaposi Sarcoma	BEFREE	31400113		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	30799057		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	12054577, 26346275, 31762817		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis	Liver Cirrhosis	BEFREE	11549587		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	12054577		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	15159028		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	19728080, 24840202		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	22646166		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	11549587, 15184870		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	12644826, 15205328, 24722255, 28038443, 30862720		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	26717985, 31462944		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	29286182, 31355266		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	24823909, 29658587, 30078000, 30746571		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	31800162		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	14562043, 17927519, 18481990, 20157568, 20305372, 21565971, 23807417, 24516048, 24722255, 25362645, 26046131, 26149387, 27615744, 27940961, 29124478 View all (4 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Squamous Cell Neoplasm	Neoplasm	BEFREE	12644826		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	25362645		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	19686745		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	18454174, 20439467, 30936459		★★★★★ ★☆☆☆☆ Found in Text Mining only
Meningioma	Meningioma	BEFREE	28493484		★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophies, Limb-Girdle	Limb-Girdle Muscular Dystrophy	BEFREE	26362252		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myotonic Dystrophy	Myotonic dystrophy	BEFREE	9371827		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	14562043, 20186023, 24532040, 26056275, 26189797, 26438629, 26602816, 26933087, 27771769, 28731284, 30078000, 30370480		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurocognitive Disorders	Neurocognitive Disorders	BEFREE	24103357		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	19781077, 20133711, 23721326, 24842888, 28912172, 30357366, 30692134		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroendocrine Tumors	Neuroendocrine Tumors	BEFREE	30014466		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	30664220		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	21862584		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	26717985, 31462944		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	29286182, 31355266		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	15827745		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinsonian Disorders	Parkinson Disease	BEFREE	24262168		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pick Disease of the Brain	Pica	BEFREE	28663553		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	14654946, 24823909, 29658587, 30078000, 30746571		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	20219773		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sleep Apnea, Central	Sleep Apnea	BEFREE	30045422		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	22016766, 27941877		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	24085785		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of tongue	Tongue carcinoma	BEFREE	20816961		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	24796666		★★★★★ ★☆☆☆☆ Found in Text Mining only
Teratoma	Teratoma	BEFREE	31253634, 31754036		★★★★★ ★☆☆☆☆ Found in Text Mining only

PNO1 (partner of NOB1 homolog)