RAD18 (RAD18 E3 ubiquitin protein ligase)

Gene

• Entrez ID: 56852
• Gene name: RAD18 E3 ubiquitin protein ligase
• Gene symbol: RAD18
• Synonyms (NCBI Gene): RNF73
• Chromosome: 3
• Chromosome location: 3p25.3
• Summary: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Sim

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT714889	hsa-miR-3129-3p	HITS-CLIP	19536157
MIRT714888	hsa-miR-5583-5p	HITS-CLIP	19536157
MIRT714887	hsa-miR-6779-3p	HITS-CLIP	19536157
MIRT714886	hsa-miR-221-5p	HITS-CLIP	19536157
MIRT714885	hsa-miR-8073	HITS-CLIP	19536157
MIRT714884	hsa-miR-3128	HITS-CLIP	19536157
MIRT714883	hsa-miR-4470	HITS-CLIP	19536157
MIRT121035	hsa-miR-618	PAR-CLIP	21572407
MIRT552017	hsa-miR-4714-5p	PAR-CLIP	21572407
MIRT552016	hsa-miR-3927-3p	PAR-CLIP	21572407
MIRT552015	hsa-miR-6831-5p	PAR-CLIP	21572407
MIRT552014	hsa-miR-3150b-3p	PAR-CLIP	21572407
MIRT552013	hsa-miR-4784	PAR-CLIP	21572407
MIRT552012	hsa-miR-3184-5p	PAR-CLIP	21572407
MIRT552011	hsa-miR-423-5p	PAR-CLIP	21572407
MIRT552010	hsa-miR-1914-3p	PAR-CLIP	21572407
MIRT552009	hsa-miR-5194	PAR-CLIP	21572407
MIRT552008	hsa-miR-6738-5p	PAR-CLIP	21572407
MIRT552007	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT552006	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT552005	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT552004	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT552003	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT552002	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT552001	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT552000	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT551999	hsa-miR-4458	PAR-CLIP	21572407
MIRT551998	hsa-miR-4500	PAR-CLIP	21572407
MIRT551997	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT121036	hsa-miR-4424	PAR-CLIP	21572407
MIRT551996	hsa-miR-4650-3p	PAR-CLIP	21572407
MIRT551994	hsa-miR-4689	PAR-CLIP	21572407
MIRT551995	hsa-miR-6858-5p	PAR-CLIP	21572407
MIRT551993	hsa-miR-6834-5p	PAR-CLIP	21572407
MIRT551992	hsa-miR-1226-5p	PAR-CLIP	21572407
MIRT551991	hsa-miR-6734-5p	PAR-CLIP	21572407
MIRT551990	hsa-miR-1304-5p	PAR-CLIP	21572407
MIRT714889	hsa-miR-3129-3p	HITS-CLIP	19536157
MIRT714888	hsa-miR-5583-5p	HITS-CLIP	19536157
MIRT714887	hsa-miR-6779-3p	HITS-CLIP	19536157
MIRT714886	hsa-miR-221-5p	HITS-CLIP	19536157
MIRT714885	hsa-miR-8073	HITS-CLIP	19536157
MIRT714884	hsa-miR-3128	HITS-CLIP	19536157
MIRT714883	hsa-miR-4470	HITS-CLIP	19536157
MIRT121035	hsa-miR-618	PAR-CLIP	21572407
MIRT552017	hsa-miR-4714-5p	PAR-CLIP	21572407
MIRT552016	hsa-miR-3927-3p	PAR-CLIP	21572407
MIRT552015	hsa-miR-6831-5p	PAR-CLIP	21572407
MIRT552014	hsa-miR-3150b-3p	PAR-CLIP	21572407
MIRT552013	hsa-miR-4784	PAR-CLIP	21572407
MIRT552012	hsa-miR-3184-5p	PAR-CLIP	21572407
MIRT552011	hsa-miR-423-5p	PAR-CLIP	21572407
MIRT552010	hsa-miR-1914-3p	PAR-CLIP	21572407
MIRT552009	hsa-miR-5194	PAR-CLIP	21572407
MIRT552008	hsa-miR-6738-5p	PAR-CLIP	21572407
MIRT552007	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT552006	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT552005	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT552004	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT552003	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT552002	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT552001	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT552000	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT551999	hsa-miR-4458	PAR-CLIP	21572407
MIRT551998	hsa-miR-4500	PAR-CLIP	21572407
MIRT551997	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT121036	hsa-miR-4424	PAR-CLIP	21572407
MIRT551996	hsa-miR-4650-3p	PAR-CLIP	21572407
MIRT551994	hsa-miR-4689	PAR-CLIP	21572407
MIRT551995	hsa-miR-6858-5p	PAR-CLIP	21572407
MIRT551993	hsa-miR-6834-5p	PAR-CLIP	21572407
MIRT551992	hsa-miR-1226-5p	PAR-CLIP	21572407
MIRT551991	hsa-miR-6734-5p	PAR-CLIP	21572407
MIRT551990	hsa-miR-1304-5p	PAR-CLIP	21572407
MIRT1287394	hsa-let-7a	CLIP-seq
MIRT1287395	hsa-let-7b	CLIP-seq
MIRT1287396	hsa-let-7c	CLIP-seq
MIRT1287397	hsa-let-7d	CLIP-seq
MIRT1287398	hsa-let-7e	CLIP-seq
MIRT1287399	hsa-let-7f	CLIP-seq
MIRT1287400	hsa-let-7g	CLIP-seq
MIRT1287401	hsa-let-7i	CLIP-seq
MIRT1287402	hsa-miR-1183	CLIP-seq
MIRT1287403	hsa-miR-1207-5p	CLIP-seq
MIRT1287404	hsa-miR-1262	CLIP-seq
MIRT1287405	hsa-miR-1265	CLIP-seq
MIRT1287406	hsa-miR-1275	CLIP-seq
MIRT1287407	hsa-miR-1298	CLIP-seq
MIRT1287408	hsa-miR-1304	CLIP-seq
MIRT1287409	hsa-miR-1305	CLIP-seq
MIRT1287410	hsa-miR-134	CLIP-seq
MIRT1287411	hsa-miR-149	CLIP-seq
MIRT1287412	hsa-miR-183	CLIP-seq
MIRT1287413	hsa-miR-186	CLIP-seq
MIRT1287414	hsa-miR-194	CLIP-seq
MIRT1287415	hsa-miR-2053	CLIP-seq
MIRT1287416	hsa-miR-214	CLIP-seq
MIRT1287417	hsa-miR-2681	CLIP-seq
MIRT1287418	hsa-miR-302a	CLIP-seq
MIRT1287419	hsa-miR-302b	CLIP-seq
MIRT1287420	hsa-miR-302c	CLIP-seq
MIRT1287421	hsa-miR-302d	CLIP-seq
MIRT1287422	hsa-miR-302e	CLIP-seq
MIRT1287423	hsa-miR-30a	CLIP-seq
MIRT1287424	hsa-miR-30b	CLIP-seq
MIRT1287425	hsa-miR-30c	CLIP-seq
MIRT1287426	hsa-miR-30d	CLIP-seq
MIRT1287427	hsa-miR-30e	CLIP-seq
MIRT1287428	hsa-miR-31	CLIP-seq
MIRT1287429	hsa-miR-3117-3p	CLIP-seq
MIRT1287430	hsa-miR-3117-5p	CLIP-seq
MIRT1287431	hsa-miR-3118	CLIP-seq
MIRT1287432	hsa-miR-3133	CLIP-seq
MIRT1287433	hsa-miR-3143	CLIP-seq
MIRT1287434	hsa-miR-3153	CLIP-seq
MIRT1287435	hsa-miR-3157-3p	CLIP-seq
MIRT1287436	hsa-miR-3160-5p	CLIP-seq
MIRT1287437	hsa-miR-3164	CLIP-seq
MIRT1287438	hsa-miR-3169	CLIP-seq
MIRT1287439	hsa-miR-3180-5p	CLIP-seq
MIRT1287440	hsa-miR-3184	CLIP-seq
MIRT1287441	hsa-miR-320a	CLIP-seq
MIRT1287442	hsa-miR-320b	CLIP-seq
MIRT1287443	hsa-miR-320c	CLIP-seq
MIRT1287444	hsa-miR-320d	CLIP-seq
MIRT1287445	hsa-miR-329	CLIP-seq
MIRT1287446	hsa-miR-338-3p	CLIP-seq
MIRT1287447	hsa-miR-34b	CLIP-seq
MIRT1287448	hsa-miR-3545-3p	CLIP-seq
MIRT1287449	hsa-miR-3607-5p	CLIP-seq
MIRT1287450	hsa-miR-3614-5p	CLIP-seq
MIRT1287451	hsa-miR-361-5p	CLIP-seq
MIRT1287452	hsa-miR-3619-5p	CLIP-seq
MIRT1287453	hsa-miR-362-3p	CLIP-seq
MIRT1287454	hsa-miR-3653	CLIP-seq
MIRT1287455	hsa-miR-3658	CLIP-seq
MIRT1287456	hsa-miR-3672	CLIP-seq
MIRT1287457	hsa-miR-3714	CLIP-seq
MIRT1287458	hsa-miR-372	CLIP-seq
MIRT1287459	hsa-miR-373	CLIP-seq
MIRT1287460	hsa-miR-380	CLIP-seq
MIRT1287461	hsa-miR-3910	CLIP-seq
MIRT1287462	hsa-miR-3913-3p	CLIP-seq
MIRT1287463	hsa-miR-3918	CLIP-seq
MIRT1287464	hsa-miR-3927	CLIP-seq
MIRT1287465	hsa-miR-3936	CLIP-seq
MIRT1287466	hsa-miR-3940-5p	CLIP-seq
MIRT1287467	hsa-miR-3941	CLIP-seq
MIRT1287468	hsa-miR-3942-3p	CLIP-seq
MIRT1287469	hsa-miR-3974	CLIP-seq
MIRT1287470	hsa-miR-4258	CLIP-seq
MIRT1287471	hsa-miR-4259	CLIP-seq
MIRT1287472	hsa-miR-4260	CLIP-seq
MIRT1287473	hsa-miR-4261	CLIP-seq
MIRT1287474	hsa-miR-4263	CLIP-seq
MIRT1287475	hsa-miR-4283	CLIP-seq
MIRT1287476	hsa-miR-4311	CLIP-seq
MIRT1287477	hsa-miR-4317	CLIP-seq
MIRT1287478	hsa-miR-4427	CLIP-seq
MIRT1287479	hsa-miR-4429	CLIP-seq
MIRT1287480	hsa-miR-4446-3p	CLIP-seq
MIRT1287481	hsa-miR-4455	CLIP-seq
MIRT1287482	hsa-miR-4464	CLIP-seq
MIRT1287483	hsa-miR-4469	CLIP-seq
MIRT1287484	hsa-miR-4476	CLIP-seq
MIRT1287485	hsa-miR-4484	CLIP-seq
MIRT1287486	hsa-miR-4489	CLIP-seq
MIRT1287487	hsa-miR-4495	CLIP-seq
MIRT1287488	hsa-miR-4496	CLIP-seq
MIRT1287489	hsa-miR-4507	CLIP-seq
MIRT1287490	hsa-miR-4511	CLIP-seq
MIRT1287491	hsa-miR-4520a-3p	CLIP-seq
MIRT1287492	hsa-miR-4525	CLIP-seq
MIRT1287493	hsa-miR-4530	CLIP-seq
MIRT1287494	hsa-miR-455-5p	CLIP-seq
MIRT1287495	hsa-miR-4633-3p	CLIP-seq
MIRT1287496	hsa-miR-4640-5p	CLIP-seq
MIRT1287497	hsa-miR-4651	CLIP-seq
MIRT1287498	hsa-miR-466	CLIP-seq
MIRT1287499	hsa-miR-4665-5p	CLIP-seq
MIRT1287500	hsa-miR-4672	CLIP-seq
MIRT1287501	hsa-miR-4680-3p	CLIP-seq
MIRT1287502	hsa-miR-4693-5p	CLIP-seq
MIRT1287503	hsa-miR-4694-5p	CLIP-seq
MIRT1287504	hsa-miR-4699-3p	CLIP-seq
MIRT1287505	hsa-miR-4701-3p	CLIP-seq
MIRT1287506	hsa-miR-4718	CLIP-seq
MIRT1287507	hsa-miR-4723-5p	CLIP-seq
MIRT1287508	hsa-miR-4726-5p	CLIP-seq
MIRT1287509	hsa-miR-4729	CLIP-seq
MIRT1287510	hsa-miR-4736	CLIP-seq
MIRT1287511	hsa-miR-4748	CLIP-seq
MIRT1287512	hsa-miR-4759	CLIP-seq
MIRT1287513	hsa-miR-4760-3p	CLIP-seq
MIRT1287514	hsa-miR-4763-3p	CLIP-seq
MIRT1287515	hsa-miR-4764-5p	CLIP-seq
MIRT1287516	hsa-miR-4775	CLIP-seq
MIRT1287517	hsa-miR-4802-3p	CLIP-seq
MIRT1287518	hsa-miR-488	CLIP-seq
MIRT1287519	hsa-miR-489	CLIP-seq
MIRT1287520	hsa-miR-490-5p	CLIP-seq
MIRT1287521	hsa-miR-498	CLIP-seq
MIRT1287522	hsa-miR-500a	CLIP-seq
MIRT1287523	hsa-miR-501-5p	CLIP-seq
MIRT1287524	hsa-miR-511	CLIP-seq
MIRT1287525	hsa-miR-519a	CLIP-seq
MIRT1287526	hsa-miR-519b-3p	CLIP-seq
MIRT1287527	hsa-miR-519c-3p	CLIP-seq
MIRT1287528	hsa-miR-520a-3p	CLIP-seq
MIRT1287529	hsa-miR-520b	CLIP-seq
MIRT1287530	hsa-miR-520c-3p	CLIP-seq
MIRT1287531	hsa-miR-520d-3p	CLIP-seq
MIRT1287532	hsa-miR-520d-5p	CLIP-seq
MIRT1287533	hsa-miR-520e	CLIP-seq
MIRT1287534	hsa-miR-524-5p	CLIP-seq
MIRT1287535	hsa-miR-542-5p	CLIP-seq
MIRT1287536	hsa-miR-543	CLIP-seq
MIRT1287537	hsa-miR-548aa	CLIP-seq
MIRT1287538	hsa-miR-548ag	CLIP-seq
MIRT1287539	hsa-miR-548ai	CLIP-seq
MIRT1287540	hsa-miR-548an	CLIP-seq
MIRT1287541	hsa-miR-548b-3p	CLIP-seq
MIRT1287542	hsa-miR-548g	CLIP-seq
MIRT1287543	hsa-miR-550a	CLIP-seq
MIRT1287544	hsa-miR-558	CLIP-seq
MIRT1287545	hsa-miR-569	CLIP-seq
MIRT1287546	hsa-miR-571	CLIP-seq
MIRT1287547	hsa-miR-576-5p	CLIP-seq
MIRT1287548	hsa-miR-579	CLIP-seq
MIRT1287549	hsa-miR-590-3p	CLIP-seq
MIRT1287550	hsa-miR-603	CLIP-seq
MIRT1287551	hsa-miR-608	CLIP-seq
MIRT1287552	hsa-miR-609	CLIP-seq
MIRT1287553	hsa-miR-624	CLIP-seq
MIRT1287554	hsa-miR-625	CLIP-seq
MIRT1287555	hsa-miR-635	CLIP-seq
MIRT1287556	hsa-miR-642a	CLIP-seq
MIRT1287557	hsa-miR-657	CLIP-seq
MIRT1287558	hsa-miR-664	CLIP-seq
MIRT1287559	hsa-miR-758	CLIP-seq
MIRT1287560	hsa-miR-761	CLIP-seq
MIRT1287561	hsa-miR-875-5p	CLIP-seq
MIRT1287562	hsa-miR-940	CLIP-seq
MIRT1287563	hsa-miR-943	CLIP-seq
MIRT1287564	hsa-miR-98	CLIP-seq
MIRT1552887	hsa-miR-15a	CLIP-seq
MIRT1552888	hsa-miR-15b	CLIP-seq
MIRT1552889	hsa-miR-16	CLIP-seq
MIRT1552890	hsa-miR-195	CLIP-seq
MIRT1552891	hsa-miR-302f	CLIP-seq
MIRT1552892	hsa-miR-424	CLIP-seq
MIRT1287507	hsa-miR-4723-5p	CLIP-seq
MIRT1552893	hsa-miR-497	CLIP-seq
MIRT1287548	hsa-miR-579	CLIP-seq
MIRT1552894	hsa-miR-939	CLIP-seq
MIRT2085110	hsa-miR-106a	CLIP-seq
MIRT2085111	hsa-miR-106b	CLIP-seq
MIRT2085112	hsa-miR-1185	CLIP-seq
MIRT2085113	hsa-miR-1252	CLIP-seq
MIRT1287404	hsa-miR-1262	CLIP-seq
MIRT2085114	hsa-miR-1269	CLIP-seq
MIRT2085115	hsa-miR-1269b	CLIP-seq
MIRT1287410	hsa-miR-134	CLIP-seq
MIRT2085116	hsa-miR-145	CLIP-seq
MIRT2085117	hsa-miR-17	CLIP-seq
MIRT2085118	hsa-miR-20a	CLIP-seq
MIRT2085119	hsa-miR-20b	CLIP-seq
MIRT2085120	hsa-miR-2110	CLIP-seq
MIRT1287418	hsa-miR-302a	CLIP-seq
MIRT1287419	hsa-miR-302b	CLIP-seq
MIRT1287420	hsa-miR-302c	CLIP-seq
MIRT1287421	hsa-miR-302d	CLIP-seq
MIRT1287422	hsa-miR-302e	CLIP-seq
MIRT1287430	hsa-miR-3117-5p	CLIP-seq
MIRT1287431	hsa-miR-3118	CLIP-seq
MIRT1287437	hsa-miR-3164	CLIP-seq
MIRT2085121	hsa-miR-3202	CLIP-seq
MIRT1287441	hsa-miR-320a	CLIP-seq
MIRT1287442	hsa-miR-320b	CLIP-seq
MIRT1287443	hsa-miR-320c	CLIP-seq
MIRT1287444	hsa-miR-320d	CLIP-seq
MIRT2085122	hsa-miR-3679-5p	CLIP-seq
MIRT2085123	hsa-miR-3682-5p	CLIP-seq
MIRT1287458	hsa-miR-372	CLIP-seq
MIRT1287459	hsa-miR-373	CLIP-seq
MIRT1287461	hsa-miR-3910	CLIP-seq
MIRT1287466	hsa-miR-3940-5p	CLIP-seq
MIRT1287468	hsa-miR-3942-3p	CLIP-seq
MIRT2085124	hsa-miR-4256	CLIP-seq
MIRT1287473	hsa-miR-4261	CLIP-seq
MIRT1287474	hsa-miR-4263	CLIP-seq
MIRT2085125	hsa-miR-4271	CLIP-seq
MIRT2085126	hsa-miR-4276	CLIP-seq
MIRT2085127	hsa-miR-432	CLIP-seq
MIRT2085128	hsa-miR-4328	CLIP-seq
MIRT1287479	hsa-miR-4429	CLIP-seq
MIRT1287483	hsa-miR-4469	CLIP-seq
MIRT1287488	hsa-miR-4496	CLIP-seq
MIRT1287489	hsa-miR-4507	CLIP-seq
MIRT2085129	hsa-miR-4509	CLIP-seq
MIRT2085130	hsa-miR-4529-3p	CLIP-seq
MIRT2085131	hsa-miR-4533	CLIP-seq
MIRT1287497	hsa-miR-4651	CLIP-seq
MIRT1287500	hsa-miR-4672	CLIP-seq
MIRT1287505	hsa-miR-4701-3p	CLIP-seq
MIRT2085132	hsa-miR-4716-5p	CLIP-seq
MIRT2085133	hsa-miR-4725-3p	CLIP-seq
MIRT2085134	hsa-miR-4744	CLIP-seq
MIRT1287516	hsa-miR-4775	CLIP-seq
MIRT2085135	hsa-miR-4787-3p	CLIP-seq
MIRT1287518	hsa-miR-488	CLIP-seq
MIRT2085136	hsa-miR-491-5p	CLIP-seq
MIRT1287525	hsa-miR-519a	CLIP-seq
MIRT1287526	hsa-miR-519b-3p	CLIP-seq
MIRT1287527	hsa-miR-519c-3p	CLIP-seq
MIRT2085137	hsa-miR-519d	CLIP-seq
MIRT1287528	hsa-miR-520a-3p	CLIP-seq
MIRT2085138	hsa-miR-520a-5p	CLIP-seq
MIRT1287529	hsa-miR-520b	CLIP-seq
MIRT1287530	hsa-miR-520c-3p	CLIP-seq
MIRT1287531	hsa-miR-520d-3p	CLIP-seq
MIRT1287533	hsa-miR-520e	CLIP-seq
MIRT2085139	hsa-miR-525-5p	CLIP-seq
MIRT1287537	hsa-miR-548aa	CLIP-seq
MIRT1287547	hsa-miR-576-5p	CLIP-seq
MIRT1287548	hsa-miR-579	CLIP-seq
MIRT1287551	hsa-miR-608	CLIP-seq
MIRT2085140	hsa-miR-617	CLIP-seq
MIRT1287559	hsa-miR-758	CLIP-seq
MIRT2085141	hsa-miR-888	CLIP-seq
MIRT2085142	hsa-miR-93	CLIP-seq
MIRT1287562	hsa-miR-940	CLIP-seq
MIRT1287394	hsa-let-7a	CLIP-seq
MIRT1287395	hsa-let-7b	CLIP-seq
MIRT1287396	hsa-let-7c	CLIP-seq
MIRT1287397	hsa-let-7d	CLIP-seq
MIRT1287398	hsa-let-7e	CLIP-seq
MIRT1287399	hsa-let-7f	CLIP-seq
MIRT1287400	hsa-let-7g	CLIP-seq
MIRT1287401	hsa-let-7i	CLIP-seq
MIRT2310610	hsa-miR-1224-5p	CLIP-seq
MIRT2310611	hsa-miR-1231	CLIP-seq
MIRT2085114	hsa-miR-1269	CLIP-seq
MIRT2085115	hsa-miR-1269b	CLIP-seq
MIRT2310612	hsa-miR-1273d	CLIP-seq
MIRT2310613	hsa-miR-138	CLIP-seq
MIRT1552887	hsa-miR-15a	CLIP-seq
MIRT1552888	hsa-miR-15b	CLIP-seq
MIRT1552889	hsa-miR-16	CLIP-seq
MIRT2310614	hsa-miR-187	CLIP-seq
MIRT1287414	hsa-miR-194	CLIP-seq
MIRT1552890	hsa-miR-195	CLIP-seq
MIRT1287417	hsa-miR-2681	CLIP-seq
MIRT1287418	hsa-miR-302a	CLIP-seq
MIRT1287419	hsa-miR-302b	CLIP-seq
MIRT1287420	hsa-miR-302c	CLIP-seq
MIRT1287421	hsa-miR-302d	CLIP-seq
MIRT1287422	hsa-miR-302e	CLIP-seq
MIRT2310615	hsa-miR-3130-3p	CLIP-seq
MIRT2310616	hsa-miR-324-5p	CLIP-seq
MIRT1287446	hsa-miR-338-3p	CLIP-seq
MIRT2310617	hsa-miR-3529	CLIP-seq
MIRT2310618	hsa-miR-3616-3p	CLIP-seq
MIRT2310619	hsa-miR-3622a-3p	CLIP-seq
MIRT2310620	hsa-miR-3622b-3p	CLIP-seq
MIRT1287458	hsa-miR-372	CLIP-seq
MIRT1287459	hsa-miR-373	CLIP-seq
MIRT2310621	hsa-miR-379	CLIP-seq
MIRT1287464	hsa-miR-3927	CLIP-seq
MIRT1287468	hsa-miR-3942-3p	CLIP-seq
MIRT1552892	hsa-miR-424	CLIP-seq
MIRT1287474	hsa-miR-4263	CLIP-seq
MIRT2310622	hsa-miR-4277	CLIP-seq
MIRT2310623	hsa-miR-4299	CLIP-seq
MIRT2085127	hsa-miR-432	CLIP-seq
MIRT1287478	hsa-miR-4427	CLIP-seq
MIRT2310624	hsa-miR-4436b-3p	CLIP-seq
MIRT2310625	hsa-miR-4451	CLIP-seq
MIRT2310626	hsa-miR-4456	CLIP-seq
MIRT2310627	hsa-miR-4471	CLIP-seq
MIRT2085130	hsa-miR-4529-3p	CLIP-seq
MIRT1287493	hsa-miR-4530	CLIP-seq
MIRT1287495	hsa-miR-4633-3p	CLIP-seq
MIRT2310628	hsa-miR-4660	CLIP-seq
MIRT1287501	hsa-miR-4680-3p	CLIP-seq
MIRT2310629	hsa-miR-4710	CLIP-seq
MIRT1287506	hsa-miR-4718	CLIP-seq
MIRT1287507	hsa-miR-4723-5p	CLIP-seq
MIRT2310630	hsa-miR-4727-5p	CLIP-seq
MIRT2310631	hsa-miR-4751	CLIP-seq
MIRT2310632	hsa-miR-4762-3p	CLIP-seq
MIRT2310633	hsa-miR-4779	CLIP-seq
MIRT2085135	hsa-miR-4787-3p	CLIP-seq
MIRT2310634	hsa-miR-4787-5p	CLIP-seq
MIRT2310635	hsa-miR-4792	CLIP-seq
MIRT1287520	hsa-miR-490-5p	CLIP-seq
MIRT1552893	hsa-miR-497	CLIP-seq
MIRT1287525	hsa-miR-519a	CLIP-seq
MIRT1287526	hsa-miR-519b-3p	CLIP-seq
MIRT1287527	hsa-miR-519c-3p	CLIP-seq
MIRT1287528	hsa-miR-520a-3p	CLIP-seq
MIRT1287529	hsa-miR-520b	CLIP-seq
MIRT1287530	hsa-miR-520c-3p	CLIP-seq
MIRT1287531	hsa-miR-520d-3p	CLIP-seq
MIRT1287533	hsa-miR-520e	CLIP-seq
MIRT2310636	hsa-miR-548q	CLIP-seq
MIRT1287544	hsa-miR-558	CLIP-seq
MIRT1287547	hsa-miR-576-5p	CLIP-seq
MIRT2085140	hsa-miR-617	CLIP-seq
MIRT2310637	hsa-miR-646	CLIP-seq
MIRT2310638	hsa-miR-671-5p	CLIP-seq
MIRT1552894	hsa-miR-939	CLIP-seq
MIRT1287564	hsa-miR-98	CLIP-seq
MIRT2085114	hsa-miR-1269	CLIP-seq
MIRT2085115	hsa-miR-1269b	CLIP-seq
MIRT1287418	hsa-miR-302a	CLIP-seq
MIRT1287419	hsa-miR-302b	CLIP-seq
MIRT1287420	hsa-miR-302c	CLIP-seq
MIRT1287421	hsa-miR-302d	CLIP-seq
MIRT1287422	hsa-miR-302e	CLIP-seq
MIRT1287458	hsa-miR-372	CLIP-seq
MIRT1287459	hsa-miR-373	CLIP-seq
MIRT1287468	hsa-miR-3942-3p	CLIP-seq
MIRT1287474	hsa-miR-4263	CLIP-seq
MIRT2085127	hsa-miR-432	CLIP-seq
MIRT2085130	hsa-miR-4529-3p	CLIP-seq
MIRT2085135	hsa-miR-4787-3p	CLIP-seq
MIRT1287525	hsa-miR-519a	CLIP-seq
MIRT1287526	hsa-miR-519b-3p	CLIP-seq
MIRT1287527	hsa-miR-519c-3p	CLIP-seq
MIRT1287528	hsa-miR-520a-3p	CLIP-seq
MIRT1287529	hsa-miR-520b	CLIP-seq
MIRT1287530	hsa-miR-520c-3p	CLIP-seq
MIRT1287531	hsa-miR-520d-3p	CLIP-seq
MIRT1287533	hsa-miR-520e	CLIP-seq
MIRT1287547	hsa-miR-576-5p	CLIP-seq
MIRT2085140	hsa-miR-617	CLIP-seq
MIRT1287462	hsa-miR-3913-3p	CLIP-seq
MIRT1287470	hsa-miR-4258	CLIP-seq
MIRT2607018	hsa-miR-4473	CLIP-seq
MIRT2607019	hsa-miR-4764-3p	CLIP-seq
MIRT1287519	hsa-miR-489	CLIP-seq
MIRT2607020	hsa-miR-495	CLIP-seq
MIRT2607021	hsa-miR-512-3p	CLIP-seq
MIRT2607022	hsa-miR-520f	CLIP-seq
MIRT2607018	hsa-miR-4473	CLIP-seq
MIRT2607021	hsa-miR-512-3p	CLIP-seq
MIRT2607022	hsa-miR-520f	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000403	Function	Y-form DNA binding	IDA	18363965
GO:0003677	Function	DNA binding	IEA
GO:0003684	Function	Damaged DNA binding	NAS	10884424
GO:0003697	Function	Single-stranded DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	18316726, 18719106, 19549727, 21422291, 21659603, 22036607, 22681887, 24981860, 25416956, 25931565, 26496610, 28514442, 32296183, 32814053, 33961781, 35849344
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	15632077, 22036607, 25023518
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	10884424
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005657	Component	Replication fork	IDA	18363965
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	15632077
GO:0005813	Component	Centrosome	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0006281	Process	DNA repair	IEA
GO:0006281	Process	DNA repair	NAS	10884424
GO:0006301	Process	Postreplication repair	IBA
GO:0006301	Process	Postreplication repair	IEA
GO:0006513	Process	Protein monoubiquitination	IBA
GO:0006513	Process	Protein monoubiquitination	IEA
GO:0006974	Process	DNA damage response	IDA	25023518
GO:0006974	Process	DNA damage response	IDA	22036607, 25931565
GO:0006974	Process	DNA damage response	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0016740	Function	Transferase activity	IEA
GO:0031593	Function	Polyubiquitin modification-dependent protein binding	IDA	22742833
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	10908344, 18363965
GO:0035861	Component	Site of double-strand break	IDA	25931565
GO:0042405	Component	Nuclear inclusion body	IDA	22036607
GO:0042802	Function	Identical protein binding	IDA	25023518
GO:0044877	Function	Protein-containing complex binding	IPI	25931565
GO:0046872	Function	Metal ion binding	IEA
GO:0051865	Process	Protein autoubiquitination	IDA	25023518
GO:0051984	Process	Positive regulation of chromosome segregation	IMP	25931565
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0097505	Component	Rad6-Rad18 complex	IBA

Other IDs

• MIM: 605256
• HGNC: 18278
• e!Ensembl: ENSG00000070950

Protein

• UniProt ID: Q9NS91
• Protein name: E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
• Protein function: E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form
• PDB: 2MRE, 2MRF, 2Y43, 2YBF, 5VF0, 8IR2, 8IR4, 9BD3
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13923	zf-C3HC4_2	24 → 63		Domain
  PF02037	SAP	248 → 282	SAP domain	Family

• Sequence:

  MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQC
  PTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPV
  ASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAP
  DPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKR
  KPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEI
  VREIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKG
  YKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREED
  SSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRA
  AESAEIEPRNKRNRN

• Sequence length: 495

Pathways

Reactome:

Recognition of DNA damage by PCNA-containing replication complex
E3 ubiquitin ligases ubiquitinate target proteins

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma	Adenocarcinoma	BEFREE	19630985		★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	19630985, 32319669	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	22509890		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	19630985		★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	35426246	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	17914568, 25913620		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	LHGDN	17914568		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	32319669, 38073330	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	29886452	Associate	★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	22509890	Associate	★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	35426246	Associate	★☆☆☆☆ Found in Text Mining only
Fanconi Anemia	Fanconi Anemia	BEFREE	20675655, 20967207, 24025411, 26819410, 26883629, 27473273		★☆☆☆☆ Found in Text Mining only
Fanconi Anemia	Fanconi anemia	Pubtator	20675655, 20937699, 20967207, 21478670	Associate	★☆☆☆☆ Found in Text Mining only
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	Anemia	BEFREE	20675655, 20967207, 24025411, 26819410, 26883629, 27473273		★☆☆☆☆ Found in Text Mining only
Focal cortical dysplasia of Taylor	Focal cortical dysplasia	Pubtator	35112146	Associate	★☆☆☆☆ Found in Text Mining only
Gastrointestinal Diseases	Gastrointestinal disease	Pubtator	27665847	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	30798132	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	31081138		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	24518219, 31081138		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	24518219, 30798132		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	30798132, 35365623	Associate	★☆☆☆☆ Found in Text Mining only
Hematologic Diseases	Hematologic disease	Pubtator	27665847	Associate	★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	29886452	Associate	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	LHGDN	17624554		★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	32319669	Stimulate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	19630985		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	17914568, 19630985, 24841992, 26883629, 31432163		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	25913620, 29721165		★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	17624554, 27473273, 27665847		★☆☆☆☆ Found in Text Mining only
Rectal Carcinoma	Rectal Carcinoma	BEFREE	31033216		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	26819410		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	29306013		★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	26683928	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of lung	Lung carcinoma	BEFREE	17624554		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of oropharynx	Oropharyngeal carcinoma	BEFREE	26683928		★☆☆☆☆ Found in Text Mining only
Werner Syndrome	Werner syndrome	Pubtator	20600238	Associate	★☆☆☆☆ Found in Text Mining only