PSG5 (pregnancy specific beta-1-glycoprotein 5)

Gene Gene information from NCBI Gene database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID 5673
Gene name Pregnancy specific beta-1-glycoprotein 5
Gene symbol PSG5
Synonyms (NCBI Gene)
FL-NCA-3PSG
Chromosome 19
Chromosome location 19q13.31
Summary The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunog
miRNA miRNA information provided by mirtarbase database.
16
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all (16)
miRTarBase ID miRNA Experiments Reference
MIRT1269731 hsa-miR-4314 CLIP-seq
MIRT1269732 hsa-miR-4667-5p CLIP-seq
MIRT1269733 hsa-miR-4700-5p CLIP-seq
MIRT1269734 hsa-miR-637 CLIP-seq
MIRT2305616 hsa-miR-335 CLIP-seq
Transcription factors Transcription factors information provided by TRRUST V2 database.
2
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
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Transcription factor Regulation Reference
KLF6 Activation 21799854;23418492
KLF6 Unknown 9083102
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
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GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21982860
GO:0005576 Component Extracellular region IEA
GO:0007157 Process Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IBA
GO:0007565 Process Female pregnancy TAS 1690992
GO:0009986 Component Cell surface IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
176394 9522 ENSG00000204941
Protein Protein information from UniProt database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q15238
Protein name Pregnancy-specific beta-1-glycoprotein 5 (PS-beta-G-5) (PSBG-5) (Pregnancy-specific glycoprotein 5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 39 → 139 Immunoglobulin V-set domain Domain
PF13895 Ig_2 148 → 235 Immunoglobulin domain Domain
PF13895 Ig_2 241 → 320 Immunoglobulin domain Domain
Tissue specificity TISSUE SPECIFICITY: Synthesized by syncytiotrophoblast of the placenta.
Sequence
Sequence length 335
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Cell surface interactions at the vascular wall
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (1)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ARTHRITIS, RHEUMATOID — CTD
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (45)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute Promyelocytic Leukemia Promyelocytic Leukemia BEFREE 2789512
★★★★★
★☆☆☆☆
Found in Text Mining only
Attention deficit hyperactivity disorder Attention Deficit Hyperactivity Disorder BEFREE 30377038
★★★★★
★☆☆☆☆
Found in Text Mining only
Autistic Disorder Autism Pubtator 28786976 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Bipolar Disorder Bipolar disorder Pubtator 28786976 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Breast Neoplasms Breast neoplasm Pubtator 28145423, 32601217 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma, Ovarian Epithelial Ovarian Epithelial carcinoma BEFREE 28145423
★★★★★
★☆☆☆☆
Found in Text Mining only
Cataplexy Cataplexy BEFREE 28366327, 31405906
★★★★★
★☆☆☆☆
Found in Text Mining only
cervical cancer Cervical Cancer BEFREE 29930344, 6604031
★★★★★
★☆☆☆☆
Found in Text Mining only
Cervix carcinoma Cervix carcinoma BEFREE 29930344
★★★★★
★☆☆☆☆
Found in Text Mining only
Down Syndrome Down Syndrome BEFREE 15032969
★★★★★
★☆☆☆☆
Found in Text Mining only