Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	56344
Gene name	Calcium binding protein 5
Gene symbol	CABP5
Synonyms (NCBI Gene)	CABP3
Chromosome	19
Chromosome location	19q13.33
Summary	The product of this gene belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of this gene is retina-spec

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017682	hsa-miR-335-5p	Microarray	18185580
MIRT857306	hsa-miR-1275	CLIP-seq
MIRT857307	hsa-miR-1470	CLIP-seq
MIRT857308	hsa-miR-184	CLIP-seq
MIRT857309	hsa-miR-219-1-3p	CLIP-seq
MIRT857310	hsa-miR-3065-5p	CLIP-seq
MIRT857311	hsa-miR-365	CLIP-seq
MIRT857312	hsa-miR-3673	CLIP-seq
MIRT857313	hsa-miR-3688-5p	CLIP-seq
MIRT857314	hsa-miR-4252	CLIP-seq
MIRT857315	hsa-miR-4260	CLIP-seq
MIRT857316	hsa-miR-4290	CLIP-seq
MIRT857317	hsa-miR-4469	CLIP-seq
MIRT857318	hsa-miR-4539	CLIP-seq
MIRT857319	hsa-miR-4651	CLIP-seq
MIRT857320	hsa-miR-4665-5p	CLIP-seq
MIRT857321	hsa-miR-4667-3p	CLIP-seq
MIRT857322	hsa-miR-551a	CLIP-seq
MIRT857323	hsa-miR-551b	CLIP-seq
MIRT857324	hsa-miR-608	CLIP-seq
MIRT1954640	hsa-miR-122	CLIP-seq
MIRT1954641	hsa-miR-299-3p	CLIP-seq
MIRT1954642	hsa-miR-3135b	CLIP-seq
MIRT1954643	hsa-miR-3175	CLIP-seq
MIRT1954644	hsa-miR-3689a-3p	CLIP-seq
MIRT1954645	hsa-miR-3689c	CLIP-seq
MIRT1954646	hsa-miR-431	CLIP-seq
MIRT1954647	hsa-miR-4648	CLIP-seq
MIRT1954648	hsa-miR-4654	CLIP-seq
MIRT1954649	hsa-miR-4711-3p	CLIP-seq
MIRT1954650	hsa-miR-4728-5p	CLIP-seq
MIRT1954651	hsa-miR-4764-5p	CLIP-seq
MIRT1954652	hsa-miR-4769-5p	CLIP-seq
MIRT1954653	hsa-miR-516a-3p	CLIP-seq
MIRT857308	hsa-miR-184	CLIP-seq
MIRT2192239	hsa-miR-3126-5p	CLIP-seq
MIRT2192240	hsa-miR-3128	CLIP-seq
MIRT2192241	hsa-miR-3201	CLIP-seq
MIRT2192242	hsa-miR-4419a	CLIP-seq
MIRT2192243	hsa-miR-4470	CLIP-seq
MIRT2192244	hsa-miR-4510	CLIP-seq
MIRT2192245	hsa-miR-4666-5p	CLIP-seq
MIRT2192246	hsa-miR-4791	CLIP-seq
MIRT2192247	hsa-miR-4793-5p	CLIP-seq
MIRT2192248	hsa-miR-4802-3p	CLIP-seq
MIRT2192249	hsa-miR-490-5p	CLIP-seq
MIRT857322	hsa-miR-551a	CLIP-seq
MIRT857323	hsa-miR-551b	CLIP-seq
MIRT2446009	hsa-miR-1182	CLIP-seq
MIRT2446010	hsa-miR-2115	CLIP-seq
MIRT2446011	hsa-miR-4633-3p	CLIP-seq
MIRT2446012	hsa-miR-516b	CLIP-seq
MIRT2446013	hsa-miR-665	CLIP-seq
MIRT2495629	hsa-miR-1236	CLIP-seq
MIRT2495630	hsa-miR-1237	CLIP-seq
MIRT2495631	hsa-miR-1248	CLIP-seq
MIRT2495629	hsa-miR-1236	CLIP-seq
MIRT2495630	hsa-miR-1237	CLIP-seq
MIRT2495631	hsa-miR-1248	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005246	Function	Calcium channel regulator activity	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005509	Function	Calcium ion binding	NAS	10625670
GO:0005515	Function	Protein binding	IPI	25416956, 29892012, 31515488, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	19338761
GO:0007165	Process	Signal transduction	NAS	10625670
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
607315	13714	ENSG00000105507

Q9NP86

Protein name

Calcium-binding protein 5 (CaBP5)

Protein function

Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials (By similarity). Involved in the transmission of light signals (By similarity). May positively

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13499	EF-hand_7	30 → 94	EF-hand domain pair	Domain
PF13499	EF-hand_7	107 → 172	EF-hand domain pair	Domain

Tissue specificity

TISSUE SPECIFICITY: Retina. {ECO:0000269|PubMed:11108966}.

Sequence

MQFPMGPACIFLRKGIAEKQRERPLGQDEIEELREAFLEFDKDRDGFISCKDLGNLMRTM
GYMPTEMELIELGQQIRMNLGGRVDFDDFVELMTPKLLAETAGMIGVQEMRDAFKEFDTN
GDGEITLVELQQAMQRLLGERLTPREISEVVREADVNGDGTVDFEEFVKMMSR

Sequence length

173

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
OBESITY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

CABP5 (calcium binding protein 5)