Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	55974
Gene name	Solute carrier family 50 member 1
Gene symbol	SLC50A1
Synonyms (NCBI Gene)	HsSWEET1RAG1AP1SCPSWEET1slv
Chromosome	1
Chromosome location	1q22

225

Show/Hide all (225)

miRTarBase ID	miRNA	Experiments	Reference
MIRT004886	hsa-miR-124-3p	Microarray	15685193
MIRT004886	hsa-miR-124-3p	Microarray	18668037
MIRT043361	hsa-miR-331-3p	CLASH	23622248
MIRT1365285	hsa-miR-1224-3p	CLIP-seq
MIRT1365286	hsa-miR-1227	CLIP-seq
MIRT1365287	hsa-miR-1254	CLIP-seq
MIRT1365288	hsa-miR-150	CLIP-seq
MIRT1365289	hsa-miR-3116	CLIP-seq
MIRT1365290	hsa-miR-3545-3p	CLIP-seq
MIRT1365291	hsa-miR-3937	CLIP-seq
MIRT1365292	hsa-miR-455-5p	CLIP-seq
MIRT1365293	hsa-miR-4635	CLIP-seq
MIRT1365294	hsa-miR-4680-5p	CLIP-seq
MIRT1365295	hsa-miR-4705	CLIP-seq
MIRT1365296	hsa-miR-4735-5p	CLIP-seq
MIRT1365297	hsa-miR-4747-3p	CLIP-seq
MIRT1365298	hsa-miR-4757-5p	CLIP-seq
MIRT1365299	hsa-miR-4775	CLIP-seq
MIRT1365300	hsa-miR-4794	CLIP-seq
MIRT1365301	hsa-miR-520g	CLIP-seq
MIRT1365302	hsa-miR-520h	CLIP-seq
MIRT1365303	hsa-miR-590-3p	CLIP-seq
MIRT1365304	hsa-miR-661	CLIP-seq
MIRT1365305	hsa-miR-124	CLIP-seq
MIRT1365306	hsa-miR-1343	CLIP-seq
MIRT1365307	hsa-miR-1976	CLIP-seq
MIRT1365308	hsa-miR-3074-3p	CLIP-seq
MIRT1365309	hsa-miR-3173-3p	CLIP-seq
MIRT1365310	hsa-miR-3714	CLIP-seq
MIRT1365311	hsa-miR-3910	CLIP-seq
MIRT1365312	hsa-miR-4279	CLIP-seq
MIRT1365313	hsa-miR-4310	CLIP-seq
MIRT1365314	hsa-miR-4722-3p	CLIP-seq
MIRT1365315	hsa-miR-494	CLIP-seq
MIRT1365316	hsa-miR-498	CLIP-seq
MIRT1365317	hsa-miR-506	CLIP-seq
MIRT1365318	hsa-miR-664	CLIP-seq
MIRT2108387	hsa-miR-106a	CLIP-seq
MIRT2108388	hsa-miR-106b	CLIP-seq
MIRT1365305	hsa-miR-124	CLIP-seq
MIRT2108389	hsa-miR-1271	CLIP-seq
MIRT1365306	hsa-miR-1343	CLIP-seq
MIRT1365288	hsa-miR-150	CLIP-seq
MIRT2108390	hsa-miR-17	CLIP-seq
MIRT2108391	hsa-miR-183	CLIP-seq
MIRT2108392	hsa-miR-18a	CLIP-seq
MIRT2108393	hsa-miR-18b	CLIP-seq
MIRT1365307	hsa-miR-1976	CLIP-seq
MIRT2108394	hsa-miR-20a	CLIP-seq
MIRT2108395	hsa-miR-20b	CLIP-seq
MIRT2108396	hsa-miR-302a	CLIP-seq
MIRT2108397	hsa-miR-302b	CLIP-seq
MIRT2108398	hsa-miR-302c	CLIP-seq
MIRT2108399	hsa-miR-302d	CLIP-seq
MIRT2108400	hsa-miR-302e	CLIP-seq
MIRT1365308	hsa-miR-3074-3p	CLIP-seq
MIRT2108401	hsa-miR-3126-3p	CLIP-seq
MIRT1365309	hsa-miR-3173-3p	CLIP-seq
MIRT2108402	hsa-miR-3192	CLIP-seq
MIRT2108403	hsa-miR-3545-5p	CLIP-seq
MIRT1365310	hsa-miR-3714	CLIP-seq
MIRT2108404	hsa-miR-372	CLIP-seq
MIRT2108405	hsa-miR-373	CLIP-seq
MIRT1365311	hsa-miR-3910	CLIP-seq
MIRT1365312	hsa-miR-4279	CLIP-seq
MIRT1365313	hsa-miR-4310	CLIP-seq
MIRT2108406	hsa-miR-4314	CLIP-seq
MIRT2108407	hsa-miR-4477b	CLIP-seq
MIRT2108408	hsa-miR-4646-5p	CLIP-seq
MIRT1365314	hsa-miR-4722-3p	CLIP-seq
MIRT2108409	hsa-miR-4735-3p	CLIP-seq
MIRT2108410	hsa-miR-4753-3p	CLIP-seq
MIRT1365298	hsa-miR-4757-5p	CLIP-seq
MIRT1365316	hsa-miR-498	CLIP-seq
MIRT1365317	hsa-miR-506	CLIP-seq
MIRT2108411	hsa-miR-5095	CLIP-seq
MIRT2108412	hsa-miR-519d	CLIP-seq
MIRT2108413	hsa-miR-520a-3p	CLIP-seq
MIRT2108414	hsa-miR-520b	CLIP-seq
MIRT2108415	hsa-miR-520c-3p	CLIP-seq
MIRT2108416	hsa-miR-520d-3p	CLIP-seq
MIRT2108417	hsa-miR-520e	CLIP-seq
MIRT1365301	hsa-miR-520g	CLIP-seq
MIRT1365302	hsa-miR-520h	CLIP-seq
MIRT2108418	hsa-miR-564	CLIP-seq
MIRT2108419	hsa-miR-659	CLIP-seq
MIRT1365318	hsa-miR-664	CLIP-seq
MIRT2108420	hsa-miR-9	CLIP-seq
MIRT2108421	hsa-miR-93	CLIP-seq
MIRT2108422	hsa-miR-96	CLIP-seq
MIRT1365305	hsa-miR-124	CLIP-seq
MIRT2332158	hsa-miR-1273f	CLIP-seq
MIRT2332159	hsa-miR-197	CLIP-seq
MIRT1365308	hsa-miR-3074-3p	CLIP-seq
MIRT2332160	hsa-miR-3149	CLIP-seq
MIRT2332161	hsa-miR-3170	CLIP-seq
MIRT1365310	hsa-miR-3714	CLIP-seq
MIRT1365311	hsa-miR-3910	CLIP-seq
MIRT2332162	hsa-miR-411	CLIP-seq
MIRT1365313	hsa-miR-4310	CLIP-seq
MIRT2108407	hsa-miR-4477b	CLIP-seq
MIRT2332163	hsa-miR-4716-5p	CLIP-seq
MIRT1365296	hsa-miR-4735-5p	CLIP-seq
MIRT1365299	hsa-miR-4775	CLIP-seq
MIRT1365317	hsa-miR-506	CLIP-seq
MIRT2332164	hsa-miR-5096	CLIP-seq
MIRT1365303	hsa-miR-590-3p	CLIP-seq
MIRT1365318	hsa-miR-664	CLIP-seq
MIRT1365306	hsa-miR-1343	CLIP-seq
MIRT1365307	hsa-miR-1976	CLIP-seq
MIRT1365312	hsa-miR-4279	CLIP-seq
MIRT1365314	hsa-miR-4722-3p	CLIP-seq
MIRT1365316	hsa-miR-498	CLIP-seq
MIRT1365287	hsa-miR-1254	CLIP-seq
MIRT2459782	hsa-miR-1260	CLIP-seq
MIRT2459783	hsa-miR-1260b	CLIP-seq
MIRT2332158	hsa-miR-1273f	CLIP-seq
MIRT1365306	hsa-miR-1343	CLIP-seq
MIRT1365288	hsa-miR-150	CLIP-seq
MIRT2459784	hsa-miR-188-3p	CLIP-seq
MIRT1365307	hsa-miR-1976	CLIP-seq
MIRT1365289	hsa-miR-3116	CLIP-seq
MIRT2108401	hsa-miR-3126-3p	CLIP-seq
MIRT2332160	hsa-miR-3149	CLIP-seq
MIRT2459785	hsa-miR-3156-3p	CLIP-seq
MIRT2332161	hsa-miR-3170	CLIP-seq
MIRT2332162	hsa-miR-411	CLIP-seq
MIRT1365312	hsa-miR-4279	CLIP-seq
MIRT1365314	hsa-miR-4722-3p	CLIP-seq
MIRT1365296	hsa-miR-4735-5p	CLIP-seq
MIRT1365299	hsa-miR-4775	CLIP-seq
MIRT1365300	hsa-miR-4794	CLIP-seq
MIRT1365316	hsa-miR-498	CLIP-seq
MIRT1365303	hsa-miR-590-3p	CLIP-seq
MIRT1365304	hsa-miR-661	CLIP-seq
MIRT1365287	hsa-miR-1254	CLIP-seq
MIRT2332158	hsa-miR-1273f	CLIP-seq
MIRT1365306	hsa-miR-1343	CLIP-seq
MIRT1365288	hsa-miR-150	CLIP-seq
MIRT1365307	hsa-miR-1976	CLIP-seq
MIRT1365289	hsa-miR-3116	CLIP-seq
MIRT2332160	hsa-miR-3149	CLIP-seq
MIRT2332161	hsa-miR-3170	CLIP-seq
MIRT2332162	hsa-miR-411	CLIP-seq
MIRT1365312	hsa-miR-4279	CLIP-seq
MIRT1365314	hsa-miR-4722-3p	CLIP-seq
MIRT1365296	hsa-miR-4735-5p	CLIP-seq
MIRT1365299	hsa-miR-4775	CLIP-seq
MIRT1365300	hsa-miR-4794	CLIP-seq
MIRT1365316	hsa-miR-498	CLIP-seq
MIRT1365303	hsa-miR-590-3p	CLIP-seq
MIRT1365304	hsa-miR-661	CLIP-seq
MIRT1365286	hsa-miR-1227	CLIP-seq
MIRT1365287	hsa-miR-1254	CLIP-seq
MIRT2108389	hsa-miR-1271	CLIP-seq
MIRT2332158	hsa-miR-1273f	CLIP-seq
MIRT1365306	hsa-miR-1343	CLIP-seq
MIRT1365288	hsa-miR-150	CLIP-seq
MIRT2332159	hsa-miR-197	CLIP-seq
MIRT1365307	hsa-miR-1976	CLIP-seq
MIRT1365289	hsa-miR-3116	CLIP-seq
MIRT2108401	hsa-miR-3126-3p	CLIP-seq
MIRT2332160	hsa-miR-3149	CLIP-seq
MIRT2332161	hsa-miR-3170	CLIP-seq
MIRT1365309	hsa-miR-3173-3p	CLIP-seq
MIRT2108402	hsa-miR-3192	CLIP-seq
MIRT2332162	hsa-miR-411	CLIP-seq
MIRT1365312	hsa-miR-4279	CLIP-seq
MIRT2108406	hsa-miR-4314	CLIP-seq
MIRT2626698	hsa-miR-4438	CLIP-seq
MIRT1365292	hsa-miR-455-5p	CLIP-seq
MIRT2108408	hsa-miR-4646-5p	CLIP-seq
MIRT2332163	hsa-miR-4716-5p	CLIP-seq
MIRT1365314	hsa-miR-4722-3p	CLIP-seq
MIRT1365296	hsa-miR-4735-5p	CLIP-seq
MIRT2108410	hsa-miR-4753-3p	CLIP-seq
MIRT1365299	hsa-miR-4775	CLIP-seq
MIRT1365300	hsa-miR-4794	CLIP-seq
MIRT1365315	hsa-miR-494	CLIP-seq
MIRT1365316	hsa-miR-498	CLIP-seq
MIRT2108411	hsa-miR-5095	CLIP-seq
MIRT2332164	hsa-miR-5096	CLIP-seq
MIRT1365303	hsa-miR-590-3p	CLIP-seq
MIRT2108419	hsa-miR-659	CLIP-seq
MIRT1365304	hsa-miR-661	CLIP-seq
MIRT2108420	hsa-miR-9	CLIP-seq
MIRT2108422	hsa-miR-96	CLIP-seq
MIRT1365286	hsa-miR-1227	CLIP-seq
MIRT1365287	hsa-miR-1254	CLIP-seq
MIRT2108389	hsa-miR-1271	CLIP-seq
MIRT2332158	hsa-miR-1273f	CLIP-seq
MIRT1365306	hsa-miR-1343	CLIP-seq
MIRT1365288	hsa-miR-150	CLIP-seq
MIRT2108392	hsa-miR-18a	CLIP-seq
MIRT2108393	hsa-miR-18b	CLIP-seq
MIRT2332159	hsa-miR-197	CLIP-seq
MIRT1365307	hsa-miR-1976	CLIP-seq
MIRT1365289	hsa-miR-3116	CLIP-seq
MIRT2108401	hsa-miR-3126-3p	CLIP-seq
MIRT2332160	hsa-miR-3149	CLIP-seq
MIRT2332161	hsa-miR-3170	CLIP-seq
MIRT1365309	hsa-miR-3173-3p	CLIP-seq
MIRT2108402	hsa-miR-3192	CLIP-seq
MIRT2108403	hsa-miR-3545-5p	CLIP-seq
MIRT2332162	hsa-miR-411	CLIP-seq
MIRT1365312	hsa-miR-4279	CLIP-seq
MIRT2108406	hsa-miR-4314	CLIP-seq
MIRT2626698	hsa-miR-4438	CLIP-seq
MIRT1365292	hsa-miR-455-5p	CLIP-seq
MIRT2108408	hsa-miR-4646-5p	CLIP-seq
MIRT1365314	hsa-miR-4722-3p	CLIP-seq
MIRT2108409	hsa-miR-4735-3p	CLIP-seq
MIRT1365296	hsa-miR-4735-5p	CLIP-seq
MIRT2108410	hsa-miR-4753-3p	CLIP-seq
MIRT1365299	hsa-miR-4775	CLIP-seq
MIRT1365300	hsa-miR-4794	CLIP-seq
MIRT1365315	hsa-miR-494	CLIP-seq
MIRT1365316	hsa-miR-498	CLIP-seq
MIRT2108411	hsa-miR-5095	CLIP-seq
MIRT2332164	hsa-miR-5096	CLIP-seq
MIRT1365303	hsa-miR-590-3p	CLIP-seq
MIRT2108419	hsa-miR-659	CLIP-seq
MIRT1365304	hsa-miR-661	CLIP-seq
MIRT2108420	hsa-miR-9	CLIP-seq
MIRT2108422	hsa-miR-96	CLIP-seq

Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005794	Component	Golgi apparatus	IDA	21107422
GO:0005794	Component	Golgi apparatus	IEA
GO:0005886	Component	Plasma membrane	IDA	21107422
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0008643	Process	Carbohydrate transport	IBA
GO:0008645	Process	Hexose transmembrane transport	TAS
GO:0012505	Component	Endomembrane system	IEA
GO:0012505	Component	Endomembrane system	ISS
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0042946	Process	Glucoside transport	IEA
GO:0042947	Function	Glucoside transmembrane transporter activity	IDA	21107422
GO:0051119	Function	Sugar transmembrane transporter activity	IBA
GO:0051119	Function	Sugar transmembrane transporter activity	IEA
GO:0051119	Function	Sugar transmembrane transporter activity	TAS

MIM	HGNC	e!Ensembl
613683	30657	ENSG00000169241

Q9BRV3

Protein name

Sugar transporter SWEET1 (HsSWEET1) (RAG1-activating protein 1) (Solute carrier family 50 member 1) (Stromal cell protein)

Protein function

Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03083	MtN3_slv	9 → 95	Sugar efflux transporter for intercellular exchange	Family
PF03083	MtN3_slv	127 → 213	Sugar efflux transporter for intercellular exchange	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed with highest expression in oviduct, epididymis and intestine. {ECO:0000269|PubMed:21107422}.

Sequence

MEAGGFLDSLIYGACVVFTLGMFSAGLSDLRHMRMTRSVDNVQFLPFLTTEVNNLGWLSY
GALKGDGILIVVNTVGAALQTLYILAYLHYCPRKRVVLLQTATLLGVLLLGYGYFWLLVP
NPEARLQQLGLFCSVFTISMYLSPLADLAKVIQTKSTQCLSYPLTIATLLTSASWCLYGF
RLRDPYIMVSNFPGIVTSFIRFWLFWKYPQEQDRNYWLLQT

Sequence length

221

Interactions

View interactions

	Reactome
			Cellular hexose transport

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
PARKINSON DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (26)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Anxiety	Anxiety Disorder	BEFREE	31653679		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety Disorders	Anxiety Disorder	BEFREE	31653679		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	30697078		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiac defects	Cardiac Defects	BEFREE	23894102		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Periodontitis	Periodontitis	BEFREE	29737428		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Heart Defects	Congenital heart defects	BEFREE	1746613		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital heart disease	Congenital Heart Disease	BEFREE	1746613		★★★★★ ★☆☆☆☆ Found in Text Mining only
Conotruncal defect	Conotruncal defect	BEFREE	1746613		★★★★★ ★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	25293974, 29194709		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	29737428		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic Retinopathy	BEFREE	30092018		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	25311416		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	23894102		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	30697078		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	30161002		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28731789		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	22071966, 25449785		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	21348431	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	GWASDB_DG	22451204		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Parkinson Disease	Parkinson disease	GWASCAT_DG	22451204		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Periodontitis	Periodontitis	BEFREE	29737428		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	30161002		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	25293974		★★★★★ ★☆☆☆☆ Found in Text Mining only
Respiratory Distress Syndrome, Adult	Respiratory Distress Syndrome	BEFREE	29137274		★★★★★ ★☆☆☆☆ Found in Text Mining only
SVEINSSON CHORIORETINAL ATROPHY	Sveinsson Chorioretinal Atrophy	BEFREE	28684768		★★★★★ ★☆☆☆☆ Found in Text Mining only
Tetralogy of Fallot	Tetralogy of Fallot	BEFREE	1746613		★★★★★ ★☆☆☆☆ Found in Text Mining only

SLC50A1 (solute carrier family 50 member 1)