Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	55860
Gene name	Actin related protein 10
Gene symbol	ACTR10
Synonyms (NCBI Gene)	ACTR11Arp10Arp11HARP11
Chromosome	14
Chromosome location	14q23.1

250

Show/Hide all (250)

miRTarBase ID	miRNA	Experiments	Reference
MIRT046144	hsa-miR-30b-5p	CLASH	23622248
MIRT053629	hsa-let-7f-5p	Microarray	22942087
MIRT616331	hsa-miR-449b-3p	HITS-CLIP	23824327
MIRT616330	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT616329	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT616331	hsa-miR-449b-3p	HITS-CLIP	23824327
MIRT616330	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT616329	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT764263	hsa-miR-140-5p	CLIP-seq
MIRT764264	hsa-miR-151-5p	CLIP-seq
MIRT764265	hsa-miR-151b	CLIP-seq
MIRT764266	hsa-miR-203	CLIP-seq
MIRT764267	hsa-miR-300	CLIP-seq
MIRT764268	hsa-miR-3122	CLIP-seq
MIRT764269	hsa-miR-3689a-3p	CLIP-seq
MIRT764270	hsa-miR-3689c	CLIP-seq
MIRT764271	hsa-miR-381	CLIP-seq
MIRT764272	hsa-miR-3909	CLIP-seq
MIRT764273	hsa-miR-3913-5p	CLIP-seq
MIRT764274	hsa-miR-4540	CLIP-seq
MIRT764275	hsa-miR-4666-3p	CLIP-seq
MIRT764276	hsa-miR-4684-5p	CLIP-seq
MIRT764277	hsa-miR-4694-3p	CLIP-seq
MIRT764278	hsa-miR-4716-5p	CLIP-seq
MIRT764279	hsa-miR-4728-5p	CLIP-seq
MIRT764280	hsa-miR-4733-5p	CLIP-seq
MIRT764281	hsa-miR-4779	CLIP-seq
MIRT764282	hsa-miR-495	CLIP-seq
MIRT764283	hsa-miR-522	CLIP-seq
MIRT764284	hsa-miR-542-3p	CLIP-seq
MIRT764285	hsa-miR-582-3p	CLIP-seq
MIRT764286	hsa-miR-711	CLIP-seq
MIRT1925165	hsa-miR-105	CLIP-seq
MIRT764264	hsa-miR-151-5p	CLIP-seq
MIRT764265	hsa-miR-151b	CLIP-seq
MIRT1925166	hsa-miR-2114	CLIP-seq
MIRT764268	hsa-miR-3122	CLIP-seq
MIRT764269	hsa-miR-3689a-3p	CLIP-seq
MIRT764270	hsa-miR-3689c	CLIP-seq
MIRT1925167	hsa-miR-374a	CLIP-seq
MIRT1925168	hsa-miR-374b	CLIP-seq
MIRT764272	hsa-miR-3909	CLIP-seq
MIRT764273	hsa-miR-3913-5p	CLIP-seq
MIRT1925169	hsa-miR-4436b-5p	CLIP-seq
MIRT764274	hsa-miR-4540	CLIP-seq
MIRT1925170	hsa-miR-4633-5p	CLIP-seq
MIRT764279	hsa-miR-4728-5p	CLIP-seq
MIRT764280	hsa-miR-4733-5p	CLIP-seq
MIRT764282	hsa-miR-495	CLIP-seq
MIRT1925171	hsa-miR-510	CLIP-seq
MIRT1925172	hsa-miR-512-5p	CLIP-seq
MIRT1925173	hsa-miR-532-5p	CLIP-seq
MIRT2166654	hsa-miR-1226	CLIP-seq
MIRT764263	hsa-miR-140-5p	CLIP-seq
MIRT764264	hsa-miR-151-5p	CLIP-seq
MIRT764265	hsa-miR-151b	CLIP-seq
MIRT2166655	hsa-miR-216a	CLIP-seq
MIRT2166656	hsa-miR-29a	CLIP-seq
MIRT2166657	hsa-miR-29b	CLIP-seq
MIRT2166658	hsa-miR-29c	CLIP-seq
MIRT2166659	hsa-miR-30a	CLIP-seq
MIRT2166660	hsa-miR-30b	CLIP-seq
MIRT2166661	hsa-miR-30c	CLIP-seq
MIRT2166662	hsa-miR-30d	CLIP-seq
MIRT2166663	hsa-miR-30e	CLIP-seq
MIRT2166664	hsa-miR-3120-3p	CLIP-seq
MIRT764268	hsa-miR-3122	CLIP-seq
MIRT2166665	hsa-miR-3160-5p	CLIP-seq
MIRT2166666	hsa-miR-3165	CLIP-seq
MIRT764269	hsa-miR-3689a-3p	CLIP-seq
MIRT764270	hsa-miR-3689c	CLIP-seq
MIRT1925167	hsa-miR-374a	CLIP-seq
MIRT1925168	hsa-miR-374b	CLIP-seq
MIRT764272	hsa-miR-3909	CLIP-seq
MIRT764273	hsa-miR-3913-5p	CLIP-seq
MIRT764274	hsa-miR-4540	CLIP-seq
MIRT764279	hsa-miR-4728-5p	CLIP-seq
MIRT764280	hsa-miR-4733-5p	CLIP-seq
MIRT2166667	hsa-miR-4762-5p	CLIP-seq
MIRT764281	hsa-miR-4779	CLIP-seq
MIRT764282	hsa-miR-495	CLIP-seq
MIRT2166668	hsa-miR-518a-5p	CLIP-seq
MIRT2166669	hsa-miR-527	CLIP-seq
MIRT2166670	hsa-miR-545	CLIP-seq
MIRT1925166	hsa-miR-2114	CLIP-seq
MIRT2383848	hsa-miR-3664-3p	CLIP-seq
MIRT2383849	hsa-miR-4252	CLIP-seq
MIRT2383850	hsa-miR-4433	CLIP-seq
MIRT2383851	hsa-miR-4459	CLIP-seq
MIRT1925170	hsa-miR-4633-5p	CLIP-seq
MIRT2383852	hsa-miR-4695-5p	CLIP-seq
MIRT2383853	hsa-miR-4768-3p	CLIP-seq
MIRT2383854	hsa-miR-4793-3p	CLIP-seq
MIRT2383855	hsa-miR-508-5p	CLIP-seq
MIRT1925171	hsa-miR-510	CLIP-seq
MIRT1925172	hsa-miR-512-5p	CLIP-seq
MIRT1925173	hsa-miR-532-5p	CLIP-seq
MIRT2383856	hsa-miR-766	CLIP-seq
MIRT764264	hsa-miR-151-5p	CLIP-seq
MIRT764265	hsa-miR-151b	CLIP-seq
MIRT2443103	hsa-miR-1908	CLIP-seq
MIRT1925166	hsa-miR-2114	CLIP-seq
MIRT764267	hsa-miR-300	CLIP-seq
MIRT764268	hsa-miR-3122	CLIP-seq
MIRT2383848	hsa-miR-3664-3p	CLIP-seq
MIRT764269	hsa-miR-3689a-3p	CLIP-seq
MIRT764270	hsa-miR-3689c	CLIP-seq
MIRT764271	hsa-miR-381	CLIP-seq
MIRT764273	hsa-miR-3913-5p	CLIP-seq
MIRT2443104	hsa-miR-3929	CLIP-seq
MIRT2443105	hsa-miR-4419b	CLIP-seq
MIRT2383850	hsa-miR-4433	CLIP-seq
MIRT2383851	hsa-miR-4459	CLIP-seq
MIRT2443106	hsa-miR-4478	CLIP-seq
MIRT1925170	hsa-miR-4633-5p	CLIP-seq
MIRT764275	hsa-miR-4666-3p	CLIP-seq
MIRT764276	hsa-miR-4684-5p	CLIP-seq
MIRT2383852	hsa-miR-4695-5p	CLIP-seq
MIRT764279	hsa-miR-4728-5p	CLIP-seq
MIRT764280	hsa-miR-4733-5p	CLIP-seq
MIRT2383853	hsa-miR-4768-3p	CLIP-seq
MIRT764281	hsa-miR-4779	CLIP-seq
MIRT2443107	hsa-miR-485-5p	CLIP-seq
MIRT1925171	hsa-miR-510	CLIP-seq
MIRT1925172	hsa-miR-512-5p	CLIP-seq
MIRT1925173	hsa-miR-532-5p	CLIP-seq
MIRT2443108	hsa-miR-663	CLIP-seq
MIRT764264	hsa-miR-151-5p	CLIP-seq
MIRT764265	hsa-miR-151b	CLIP-seq
MIRT1925166	hsa-miR-2114	CLIP-seq
MIRT764268	hsa-miR-3122	CLIP-seq
MIRT2383848	hsa-miR-3664-3p	CLIP-seq
MIRT764269	hsa-miR-3689a-3p	CLIP-seq
MIRT764270	hsa-miR-3689c	CLIP-seq
MIRT764273	hsa-miR-3913-5p	CLIP-seq
MIRT2443104	hsa-miR-3929	CLIP-seq
MIRT2443105	hsa-miR-4419b	CLIP-seq
MIRT2383850	hsa-miR-4433	CLIP-seq
MIRT2383851	hsa-miR-4459	CLIP-seq
MIRT2443106	hsa-miR-4478	CLIP-seq
MIRT1925170	hsa-miR-4633-5p	CLIP-seq
MIRT2383852	hsa-miR-4695-5p	CLIP-seq
MIRT764279	hsa-miR-4728-5p	CLIP-seq
MIRT764280	hsa-miR-4733-5p	CLIP-seq
MIRT2383853	hsa-miR-4768-3p	CLIP-seq
MIRT764281	hsa-miR-4779	CLIP-seq
MIRT2443107	hsa-miR-485-5p	CLIP-seq
MIRT1925171	hsa-miR-510	CLIP-seq
MIRT1925172	hsa-miR-512-5p	CLIP-seq
MIRT1925173	hsa-miR-532-5p	CLIP-seq
MIRT2469123	hsa-miR-1257	CLIP-seq
MIRT2469124	hsa-miR-142-5p	CLIP-seq
MIRT764264	hsa-miR-151-5p	CLIP-seq
MIRT764265	hsa-miR-151b	CLIP-seq
MIRT2469125	hsa-miR-190	CLIP-seq
MIRT2443103	hsa-miR-1908	CLIP-seq
MIRT2469126	hsa-miR-190b	CLIP-seq
MIRT1925166	hsa-miR-2114	CLIP-seq
MIRT764267	hsa-miR-300	CLIP-seq
MIRT764268	hsa-miR-3122	CLIP-seq
MIRT2469127	hsa-miR-3163	CLIP-seq
MIRT2166666	hsa-miR-3165	CLIP-seq
MIRT2469128	hsa-miR-340	CLIP-seq
MIRT2469129	hsa-miR-3611	CLIP-seq
MIRT2469130	hsa-miR-3646	CLIP-seq
MIRT2469131	hsa-miR-3662	CLIP-seq
MIRT2383848	hsa-miR-3664-3p	CLIP-seq
MIRT2469132	hsa-miR-3668	CLIP-seq
MIRT764269	hsa-miR-3689a-3p	CLIP-seq
MIRT764270	hsa-miR-3689c	CLIP-seq
MIRT1925167	hsa-miR-374a	CLIP-seq
MIRT1925168	hsa-miR-374b	CLIP-seq
MIRT764271	hsa-miR-381	CLIP-seq
MIRT764272	hsa-miR-3909	CLIP-seq
MIRT764273	hsa-miR-3913-5p	CLIP-seq
MIRT2443104	hsa-miR-3929	CLIP-seq
MIRT2469133	hsa-miR-410	CLIP-seq
MIRT2469134	hsa-miR-4289	CLIP-seq
MIRT2469135	hsa-miR-4329	CLIP-seq
MIRT2443105	hsa-miR-4419b	CLIP-seq
MIRT2469136	hsa-miR-4422	CLIP-seq
MIRT2383850	hsa-miR-4433	CLIP-seq
MIRT1925169	hsa-miR-4436b-5p	CLIP-seq
MIRT2383851	hsa-miR-4459	CLIP-seq
MIRT2443106	hsa-miR-4478	CLIP-seq
MIRT764274	hsa-miR-4540	CLIP-seq
MIRT1925170	hsa-miR-4633-5p	CLIP-seq
MIRT2469137	hsa-miR-4651	CLIP-seq
MIRT764275	hsa-miR-4666-3p	CLIP-seq
MIRT764276	hsa-miR-4684-5p	CLIP-seq
MIRT2383852	hsa-miR-4695-5p	CLIP-seq
MIRT764279	hsa-miR-4728-5p	CLIP-seq
MIRT764280	hsa-miR-4733-5p	CLIP-seq
MIRT2383853	hsa-miR-4768-3p	CLIP-seq
MIRT764281	hsa-miR-4779	CLIP-seq
MIRT2469138	hsa-miR-4786-5p	CLIP-seq
MIRT2469139	hsa-miR-4793-5p	CLIP-seq
MIRT2469140	hsa-miR-4794	CLIP-seq
MIRT2443107	hsa-miR-485-5p	CLIP-seq
MIRT764282	hsa-miR-495	CLIP-seq
MIRT1925171	hsa-miR-510	CLIP-seq
MIRT1925172	hsa-miR-512-5p	CLIP-seq
MIRT1925173	hsa-miR-532-5p	CLIP-seq
MIRT2469141	hsa-miR-548c-3p	CLIP-seq
MIRT2469142	hsa-miR-608	CLIP-seq
MIRT2443108	hsa-miR-663	CLIP-seq
MIRT2469143	hsa-miR-769-5p	CLIP-seq
MIRT2469123	hsa-miR-1257	CLIP-seq
MIRT2469124	hsa-miR-142-5p	CLIP-seq
MIRT764264	hsa-miR-151-5p	CLIP-seq
MIRT764265	hsa-miR-151b	CLIP-seq
MIRT2469125	hsa-miR-190	CLIP-seq
MIRT2443103	hsa-miR-1908	CLIP-seq
MIRT2469126	hsa-miR-190b	CLIP-seq
MIRT1925166	hsa-miR-2114	CLIP-seq
MIRT764267	hsa-miR-300	CLIP-seq
MIRT764268	hsa-miR-3122	CLIP-seq
MIRT2166666	hsa-miR-3165	CLIP-seq
MIRT2469128	hsa-miR-340	CLIP-seq
MIRT2469129	hsa-miR-3611	CLIP-seq
MIRT2383848	hsa-miR-3664-3p	CLIP-seq
MIRT764269	hsa-miR-3689a-3p	CLIP-seq
MIRT764270	hsa-miR-3689c	CLIP-seq
MIRT1925167	hsa-miR-374a	CLIP-seq
MIRT1925168	hsa-miR-374b	CLIP-seq
MIRT764271	hsa-miR-381	CLIP-seq
MIRT764272	hsa-miR-3909	CLIP-seq
MIRT764273	hsa-miR-3913-5p	CLIP-seq
MIRT2469133	hsa-miR-410	CLIP-seq
MIRT2469134	hsa-miR-4289	CLIP-seq
MIRT2469136	hsa-miR-4422	CLIP-seq
MIRT2383850	hsa-miR-4433	CLIP-seq
MIRT1925169	hsa-miR-4436b-5p	CLIP-seq
MIRT2383851	hsa-miR-4459	CLIP-seq
MIRT764274	hsa-miR-4540	CLIP-seq
MIRT1925170	hsa-miR-4633-5p	CLIP-seq
MIRT2469137	hsa-miR-4651	CLIP-seq
MIRT764275	hsa-miR-4666-3p	CLIP-seq
MIRT764276	hsa-miR-4684-5p	CLIP-seq
MIRT2383852	hsa-miR-4695-5p	CLIP-seq
MIRT764279	hsa-miR-4728-5p	CLIP-seq
MIRT764280	hsa-miR-4733-5p	CLIP-seq
MIRT2383853	hsa-miR-4768-3p	CLIP-seq
MIRT764281	hsa-miR-4779	CLIP-seq
MIRT764282	hsa-miR-495	CLIP-seq
MIRT1925171	hsa-miR-510	CLIP-seq
MIRT1925172	hsa-miR-512-5p	CLIP-seq
MIRT1925173	hsa-miR-532-5p	CLIP-seq
MIRT2469142	hsa-miR-608	CLIP-seq
MIRT2443108	hsa-miR-663	CLIP-seq

Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005576	Component	Extracellular region	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005869	Component	Dynactin complex	IBA
GO:0005869	Component	Dynactin complex	IEA
GO:0007018	Process	Microtubule-based movement	IEA
GO:0035578	Component	Azurophil granule lumen	TAS
GO:0098958	Process	Retrograde axonal transport of mitochondrion	IBA
GO:1904115	Component	Axon cytoplasm	IEA
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

MIM	HGNC	e!Ensembl
619731	17372	ENSG00000131966

Q9NZ32

Protein name

Actin-related protein 10 (Actin-related protein 11) (hARP11)

Protein function

Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00022	Actin	10 → 70	Actin	Family
PF00022	Actin	65 → 389	Actin	Family

Sequence

MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMPKPVRVVQYNIN
TEELYSYLKEFIHILYFRHLLVNPRDRRVVIIESVLCPSHFRETLTRVLFKYFEVPSVLL
APSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLL
EQCTVDTSVAKEQSLPSVMGSVPEGVLEDIKARTCFVSDLKRGLKIQAAKFNIDGNNERP
SPPPNVDYPLDGEKILHILGSIRDSVVEILFEQDNEEQSVATLILDSLIQCPIDTRKQLA
ENLVVIGGTSMLPGFLHRLLAEIRYLVEKPKYKKALGTKTFRIHTPPAKANCVAWLGGAI
FGALQDILGSRSVSKEYYNQTGRIPDWCSLNNPPLEMMFDVGKTQPPLMKRAFSTEK

Sequence length

417

Interactions

View interactions

	KEGG		Reactome
	Motor proteins Amyotrophic lateral sclerosis Huntington disease Pathways of neurodegeneration - multiple diseases Salmonella infection		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
NON-MELANOMA SKIN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	11162478, 14651955		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	34166375	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	14651955		★★★★★ ★☆☆☆☆ Found in Text Mining only

ACTR10 (actin related protein 10)