Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	55735
Gene name	DnaJ heat shock protein family (Hsp40) member C11
Gene symbol	DNAJC11
Synonyms (NCBI Gene)	dJ126A5.1
Chromosome	1
Chromosome location	1p36.31

258

Show/Hide all (258)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025867	hsa-miR-7-5p	Sequencing	20371350
MIRT029741	hsa-miR-26b-5p	Sequencing	20371350
MIRT032315	hsa-let-7b-5p	Proteomics	18668040
MIRT043176	hsa-miR-324-5p	CLASH	23622248
MIRT041301	hsa-miR-193b-3p	CLASH	23622248
MIRT709713	hsa-miR-6858-3p	HITS-CLIP	19536157
MIRT709712	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT709711	hsa-miR-6134	HITS-CLIP	19536157
MIRT709710	hsa-miR-671-5p	HITS-CLIP	19536157
MIRT713457	hsa-miR-3689d	HITS-CLIP	19536157
MIRT713458	hsa-miR-6851-5p	HITS-CLIP	19536157
MIRT709709	hsa-miR-4747-5p	HITS-CLIP	19536157
MIRT709707	hsa-miR-5196-5p	HITS-CLIP	19536157
MIRT709708	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT713456	hsa-miR-4709-3p	HITS-CLIP	19536157
MIRT709713	hsa-miR-6858-3p	HITS-CLIP	19536157
MIRT709712	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT709711	hsa-miR-6134	HITS-CLIP	19536157
MIRT709710	hsa-miR-671-5p	HITS-CLIP	19536157
MIRT713457	hsa-miR-3689d	HITS-CLIP	19536157
MIRT713458	hsa-miR-6851-5p	HITS-CLIP	19536157
MIRT709709	hsa-miR-4747-5p	HITS-CLIP	19536157
MIRT709707	hsa-miR-5196-5p	HITS-CLIP	19536157
MIRT709708	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT713456	hsa-miR-4709-3p	HITS-CLIP	19536157
MIRT709713	hsa-miR-6858-3p	HITS-CLIP	19536157
MIRT709712	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT709711	hsa-miR-6134	HITS-CLIP	19536157
MIRT709710	hsa-miR-671-5p	HITS-CLIP	19536157
MIRT713457	hsa-miR-3689d	HITS-CLIP	19536157
MIRT713458	hsa-miR-6851-5p	HITS-CLIP	19536157
MIRT709709	hsa-miR-4747-5p	HITS-CLIP	19536157
MIRT709707	hsa-miR-5196-5p	HITS-CLIP	19536157
MIRT709708	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT713456	hsa-miR-4709-3p	HITS-CLIP	19536157
MIRT709713	hsa-miR-6858-3p	HITS-CLIP	19536157
MIRT709712	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT709711	hsa-miR-6134	HITS-CLIP	19536157
MIRT709710	hsa-miR-671-5p	HITS-CLIP	19536157
MIRT709709	hsa-miR-4747-5p	HITS-CLIP	19536157
MIRT709707	hsa-miR-5196-5p	HITS-CLIP	19536157
MIRT709708	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT440800	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440800	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT709713	hsa-miR-6858-3p	HITS-CLIP	19536157
MIRT709712	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT709711	hsa-miR-6134	HITS-CLIP	19536157
MIRT709710	hsa-miR-671-5p	HITS-CLIP	19536157
MIRT713457	hsa-miR-3689d	HITS-CLIP	19536157
MIRT713458	hsa-miR-6851-5p	HITS-CLIP	19536157
MIRT709709	hsa-miR-4747-5p	HITS-CLIP	19536157
MIRT709707	hsa-miR-5196-5p	HITS-CLIP	19536157
MIRT709708	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT713456	hsa-miR-4709-3p	HITS-CLIP	19536157
MIRT709713	hsa-miR-6858-3p	HITS-CLIP	19536157
MIRT709712	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT709711	hsa-miR-6134	HITS-CLIP	19536157
MIRT709710	hsa-miR-671-5p	HITS-CLIP	19536157
MIRT713457	hsa-miR-3689d	HITS-CLIP	19536157
MIRT713458	hsa-miR-6851-5p	HITS-CLIP	19536157
MIRT709709	hsa-miR-4747-5p	HITS-CLIP	19536157
MIRT709707	hsa-miR-5196-5p	HITS-CLIP	19536157
MIRT709708	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT713456	hsa-miR-4709-3p	HITS-CLIP	19536157
MIRT709713	hsa-miR-6858-3p	HITS-CLIP	19536157
MIRT709712	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT709711	hsa-miR-6134	HITS-CLIP	19536157
MIRT709710	hsa-miR-671-5p	HITS-CLIP	19536157
MIRT713457	hsa-miR-3689d	HITS-CLIP	19536157
MIRT713458	hsa-miR-6851-5p	HITS-CLIP	19536157
MIRT709709	hsa-miR-4747-5p	HITS-CLIP	19536157
MIRT709707	hsa-miR-5196-5p	HITS-CLIP	19536157
MIRT709708	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT713456	hsa-miR-4709-3p	HITS-CLIP	19536157
MIRT709713	hsa-miR-6858-3p	HITS-CLIP	19536157
MIRT709712	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT709711	hsa-miR-6134	HITS-CLIP	19536157
MIRT709710	hsa-miR-671-5p	HITS-CLIP	19536157
MIRT709709	hsa-miR-4747-5p	HITS-CLIP	19536157
MIRT709707	hsa-miR-5196-5p	HITS-CLIP	19536157
MIRT709708	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT940491	hsa-miR-1182	CLIP-seq
MIRT940492	hsa-miR-125a-5p	CLIP-seq
MIRT940493	hsa-miR-125b	CLIP-seq
MIRT940494	hsa-miR-2467-3p	CLIP-seq
MIRT940495	hsa-miR-2467-5p	CLIP-seq
MIRT940496	hsa-miR-3141	CLIP-seq
MIRT940497	hsa-miR-3197	CLIP-seq
MIRT940498	hsa-miR-3202	CLIP-seq
MIRT940499	hsa-miR-423-3p	CLIP-seq
MIRT940500	hsa-miR-4319	CLIP-seq
MIRT940501	hsa-miR-4467	CLIP-seq
MIRT940502	hsa-miR-4476	CLIP-seq
MIRT940503	hsa-miR-4511	CLIP-seq
MIRT940504	hsa-miR-4710	CLIP-seq
MIRT940505	hsa-miR-4732-3p	CLIP-seq
MIRT940506	hsa-miR-4733-5p	CLIP-seq
MIRT940507	hsa-miR-4792	CLIP-seq
MIRT940508	hsa-miR-515-3p	CLIP-seq
MIRT940509	hsa-miR-519e	CLIP-seq
MIRT940510	hsa-miR-544	CLIP-seq
MIRT940511	hsa-miR-615-5p	CLIP-seq
MIRT940512	hsa-miR-670	CLIP-seq
MIRT940513	hsa-miR-765	CLIP-seq
MIRT1547994	hsa-miR-1225-5p	CLIP-seq
MIRT1547995	hsa-miR-2861	CLIP-seq
MIRT940511	hsa-miR-615-5p	CLIP-seq
MIRT1547996	hsa-miR-661	CLIP-seq
MIRT1978107	hsa-miR-1207-5p	CLIP-seq
MIRT1547994	hsa-miR-1225-5p	CLIP-seq
MIRT940492	hsa-miR-125a-5p	CLIP-seq
MIRT940493	hsa-miR-125b	CLIP-seq
MIRT1978108	hsa-miR-1262	CLIP-seq
MIRT1978109	hsa-miR-1291	CLIP-seq
MIRT1978110	hsa-miR-147b	CLIP-seq
MIRT1978111	hsa-miR-1914	CLIP-seq
MIRT940494	hsa-miR-2467-3p	CLIP-seq
MIRT940495	hsa-miR-2467-5p	CLIP-seq
MIRT1547995	hsa-miR-2861	CLIP-seq
MIRT1978112	hsa-miR-2964a-5p	CLIP-seq
MIRT1978113	hsa-miR-3127-5p	CLIP-seq
MIRT1978114	hsa-miR-3140-3p	CLIP-seq
MIRT1978115	hsa-miR-3151	CLIP-seq
MIRT1978116	hsa-miR-3157-5p	CLIP-seq
MIRT1978117	hsa-miR-3616-3p	CLIP-seq
MIRT1978118	hsa-miR-3650	CLIP-seq
MIRT1978119	hsa-miR-3918	CLIP-seq
MIRT1978120	hsa-miR-3940-5p	CLIP-seq
MIRT1978121	hsa-miR-3960	CLIP-seq
MIRT1978122	hsa-miR-4292	CLIP-seq
MIRT940500	hsa-miR-4319	CLIP-seq
MIRT1978123	hsa-miR-4436b-3p	CLIP-seq
MIRT1978124	hsa-miR-4455	CLIP-seq
MIRT1978125	hsa-miR-4502	CLIP-seq
MIRT1978126	hsa-miR-4507	CLIP-seq
MIRT1978127	hsa-miR-450b-3p	CLIP-seq
MIRT1978128	hsa-miR-451b	CLIP-seq
MIRT1978129	hsa-miR-4681	CLIP-seq
MIRT1978130	hsa-miR-4691-3p	CLIP-seq
MIRT1978131	hsa-miR-4701-3p	CLIP-seq
MIRT940504	hsa-miR-4710	CLIP-seq
MIRT1978132	hsa-miR-4711-3p	CLIP-seq
MIRT1978133	hsa-miR-4713-3p	CLIP-seq
MIRT1978134	hsa-miR-4721	CLIP-seq
MIRT1978135	hsa-miR-4731-5p	CLIP-seq
MIRT940505	hsa-miR-4732-3p	CLIP-seq
MIRT1978136	hsa-miR-4747-3p	CLIP-seq
MIRT1978137	hsa-miR-4763-3p	CLIP-seq
MIRT1978138	hsa-miR-4763-5p	CLIP-seq
MIRT940507	hsa-miR-4792	CLIP-seq
MIRT1978139	hsa-miR-545	CLIP-seq
MIRT1978140	hsa-miR-592	CLIP-seq
MIRT1978141	hsa-miR-597	CLIP-seq
MIRT1978142	hsa-miR-609	CLIP-seq
MIRT940511	hsa-miR-615-5p	CLIP-seq
MIRT1978143	hsa-miR-638	CLIP-seq
MIRT1547996	hsa-miR-661	CLIP-seq
MIRT940512	hsa-miR-670	CLIP-seq
MIRT1978144	hsa-miR-769-3p	CLIP-seq
MIRT940491	hsa-miR-1182	CLIP-seq
MIRT940492	hsa-miR-125a-5p	CLIP-seq
MIRT940493	hsa-miR-125b	CLIP-seq
MIRT940494	hsa-miR-2467-3p	CLIP-seq
MIRT940495	hsa-miR-2467-5p	CLIP-seq
MIRT1547995	hsa-miR-2861	CLIP-seq
MIRT940498	hsa-miR-3202	CLIP-seq
MIRT940500	hsa-miR-4319	CLIP-seq
MIRT940502	hsa-miR-4476	CLIP-seq
MIRT940505	hsa-miR-4732-3p	CLIP-seq
MIRT940506	hsa-miR-4733-5p	CLIP-seq
MIRT940510	hsa-miR-544	CLIP-seq
MIRT940511	hsa-miR-615-5p	CLIP-seq
MIRT1547996	hsa-miR-661	CLIP-seq
MIRT940512	hsa-miR-670	CLIP-seq
MIRT940513	hsa-miR-765	CLIP-seq
MIRT2213661	hsa-miR-922	CLIP-seq
MIRT1547994	hsa-miR-1225-5p	CLIP-seq
MIRT940492	hsa-miR-125a-5p	CLIP-seq
MIRT940493	hsa-miR-125b	CLIP-seq
MIRT940494	hsa-miR-2467-3p	CLIP-seq
MIRT940495	hsa-miR-2467-5p	CLIP-seq
MIRT1547995	hsa-miR-2861	CLIP-seq
MIRT940500	hsa-miR-4319	CLIP-seq
MIRT940505	hsa-miR-4732-3p	CLIP-seq
MIRT940511	hsa-miR-615-5p	CLIP-seq
MIRT1547996	hsa-miR-661	CLIP-seq
MIRT940512	hsa-miR-670	CLIP-seq
MIRT2517527	hsa-miR-10a	CLIP-seq
MIRT2517528	hsa-miR-10b	CLIP-seq
MIRT1978107	hsa-miR-1207-5p	CLIP-seq
MIRT2517529	hsa-miR-1233	CLIP-seq
MIRT2517530	hsa-miR-129-3p	CLIP-seq
MIRT2517531	hsa-miR-1470	CLIP-seq
MIRT1978111	hsa-miR-1914	CLIP-seq
MIRT2517532	hsa-miR-3065-3p	CLIP-seq
MIRT1978113	hsa-miR-3127-5p	CLIP-seq
MIRT940496	hsa-miR-3141	CLIP-seq
MIRT2517533	hsa-miR-3153	CLIP-seq
MIRT2517534	hsa-miR-3189-3p	CLIP-seq
MIRT2517535	hsa-miR-339-5p	CLIP-seq
MIRT1978117	hsa-miR-3616-3p	CLIP-seq
MIRT2517536	hsa-miR-362-5p	CLIP-seq
MIRT2517537	hsa-miR-3907	CLIP-seq
MIRT1978119	hsa-miR-3918	CLIP-seq
MIRT1978121	hsa-miR-3960	CLIP-seq
MIRT940499	hsa-miR-423-3p	CLIP-seq
MIRT1978123	hsa-miR-4436b-3p	CLIP-seq
MIRT940501	hsa-miR-4467	CLIP-seq
MIRT940503	hsa-miR-4511	CLIP-seq
MIRT2517538	hsa-miR-4640-5p	CLIP-seq
MIRT2517539	hsa-miR-4667-3p	CLIP-seq
MIRT2517540	hsa-miR-4668-5p	CLIP-seq
MIRT2517541	hsa-miR-4704-5p	CLIP-seq
MIRT940504	hsa-miR-4710	CLIP-seq
MIRT1978134	hsa-miR-4721	CLIP-seq
MIRT2517542	hsa-miR-4726-5p	CLIP-seq
MIRT1978137	hsa-miR-4763-3p	CLIP-seq
MIRT940507	hsa-miR-4792	CLIP-seq
MIRT2517543	hsa-miR-500b	CLIP-seq
MIRT2517544	hsa-miR-570	CLIP-seq
MIRT2517545	hsa-miR-604	CLIP-seq
MIRT2517546	hsa-miR-642a	CLIP-seq
MIRT2517547	hsa-miR-665	CLIP-seq
MIRT2517548	hsa-miR-873	CLIP-seq
MIRT1978107	hsa-miR-1207-5p	CLIP-seq
MIRT2517529	hsa-miR-1233	CLIP-seq
MIRT2517530	hsa-miR-129-3p	CLIP-seq
MIRT2517531	hsa-miR-1470	CLIP-seq
MIRT1978111	hsa-miR-1914	CLIP-seq
MIRT2517532	hsa-miR-3065-3p	CLIP-seq
MIRT1978113	hsa-miR-3127-5p	CLIP-seq
MIRT940496	hsa-miR-3141	CLIP-seq
MIRT2517533	hsa-miR-3153	CLIP-seq
MIRT2517534	hsa-miR-3189-3p	CLIP-seq
MIRT1978117	hsa-miR-3616-3p	CLIP-seq
MIRT2517536	hsa-miR-362-5p	CLIP-seq
MIRT2517537	hsa-miR-3907	CLIP-seq
MIRT1978119	hsa-miR-3918	CLIP-seq
MIRT1978121	hsa-miR-3960	CLIP-seq
MIRT940499	hsa-miR-423-3p	CLIP-seq
MIRT1978123	hsa-miR-4436b-3p	CLIP-seq
MIRT940501	hsa-miR-4467	CLIP-seq
MIRT940503	hsa-miR-4511	CLIP-seq
MIRT2517538	hsa-miR-4640-5p	CLIP-seq
MIRT2517539	hsa-miR-4667-3p	CLIP-seq
MIRT2517540	hsa-miR-4668-5p	CLIP-seq
MIRT940504	hsa-miR-4710	CLIP-seq
MIRT1978134	hsa-miR-4721	CLIP-seq
MIRT2517542	hsa-miR-4726-5p	CLIP-seq
MIRT2679330	hsa-miR-4755-3p	CLIP-seq
MIRT1978137	hsa-miR-4763-3p	CLIP-seq
MIRT940507	hsa-miR-4792	CLIP-seq
MIRT2517543	hsa-miR-500b	CLIP-seq
MIRT2517544	hsa-miR-570	CLIP-seq
MIRT2517545	hsa-miR-604	CLIP-seq
MIRT2517546	hsa-miR-642a	CLIP-seq
MIRT2517547	hsa-miR-665	CLIP-seq
MIRT2517548	hsa-miR-873	CLIP-seq

Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001401	Component	SAM complex	HDA	26477565
GO:0001401	Component	SAM complex	IDA	25997101
GO:0005515	Function	Protein binding	IPI	17500595, 32296183, 33961781, 35271311
GO:0005654	Component	Nucleoplasm	IDA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	25997101
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005741	Component	Mitochondrial outer membrane	IMP	25111180
GO:0007007	Process	Inner mitochondrial membrane organization	IC	26477565
GO:0016020	Component	Membrane	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0042407	Process	Cristae formation	IBA
GO:0042407	Process	Cristae formation	IEA
GO:0042407	Process	Cristae formation	IMP	25111180
GO:0061617	Component	MICOS complex	IDA	25997101
GO:0140275	Component	MIB complex	HDA	26477565

MIM	HGNC	e!Ensembl
614827	25570	ENSG00000007923

Q9NVH1

Protein name

DnaJ homolog subfamily C member 11

Protein function

[Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex. {ECO:0000269|PubMed:25111180, EC

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00226	DnaJ	14 → 79	DnaJ domain	Domain
PF11875	DUF3395	410 → 549	Domain of unknown function (DUF3395)	Family

Sequence

MATALSEEELDNEDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFN
LVHQAYEVLSDPQTRAIYDIYGKRGLEMEGWEVVERRRTPAEIREEFERLQREREERRLQ
QRTNPKGTISVGVDATDLFDRYDEEYEDVSGSSFPQIEINKMHISQSIEAPLTATDTAIL
SGSLSTQNGNGGGSINFALRRVTSAKGWGELEFGAGDLQGPLFGLKLFRNLTPRCFVTTN
CALQFSSRGIRPGLTTVLARNLDKNTVGYLQWRWGIQSAMNTSIVRDTKTSHFTVALQLG
IPHSFALISYQHKFQDDDQTRVKGSLKAGFFGTVVEYGAERKISRHSVLGAAVSVGVPQG
VSLKVKLNRASQTYFFPIHLTDQLLPSAMFYATVGPLVVYFAMHRLIIKPYLRAQKEKEL
EKQRESAATDVLQKKQEAESAVRLMQESVRRIIEAEESRMGLIIVNAWYGKFVNDKSRKS
EKVKVIDVTVPLQCLVKDSKLILTEASKAGLPGFYDPCVGEEKNLKVLYQFRGVLHQVMV
LDSEALRIPKQSHRIDTDG

Sequence length

559

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (6)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Neoplasms	Neoplasms	BEFREE	12964007	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	12964007, 17222547	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuromuscular Diseases	Neuromuscular Diseases	BEFREE	31550165	★★★★★ ★☆☆☆☆ Found in Text Mining only

DNAJC11 (DnaJ heat shock protein family (Hsp40) member C11)