N4BP2 (NEDD4 binding protein 2)

Gene

• Entrez ID: 55728
• Gene name: NEDD4 binding protein 2
• Gene symbol: N4BP2
• Synonyms (NCBI Gene): B3BP
• Chromosome: 4
• Chromosome location: 4p14
• Summary: This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural pr

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT026566	hsa-miR-192-5p	Microarray	19074876
MIRT048611	hsa-miR-99a-5p	CLASH	23622248
MIRT048436	hsa-miR-100-5p	CLASH	23622248
MIRT714966	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT714965	hsa-miR-4753-3p	HITS-CLIP	19536157
MIRT714964	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT714963	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT714962	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT212860	hsa-miR-30d-5p	PAR-CLIP	22100165
MIRT212862	hsa-miR-30b-5p	PAR-CLIP	22100165
MIRT212858	hsa-miR-30a-5p	PAR-CLIP	22100165
MIRT212864	hsa-miR-30e-5p	PAR-CLIP	22100165
MIRT212859	hsa-miR-30c-5p	PAR-CLIP	22100165
MIRT212861	hsa-miR-200b-3p	PAR-CLIP	22100165
MIRT212863	hsa-miR-200c-3p	PAR-CLIP	22100165
MIRT212865	hsa-miR-429	PAR-CLIP	22100165
MIRT448666	hsa-miR-8084	PAR-CLIP	22100165
MIRT448665	hsa-miR-1183	PAR-CLIP	22100165
MIRT212867	hsa-miR-3607-3p	PAR-CLIP	22100165
MIRT448664	hsa-miR-183-3p	PAR-CLIP	22100165
MIRT448663	hsa-miR-4452	PAR-CLIP	22100165
MIRT212860	hsa-miR-30d-5p	PAR-CLIP	22100165
MIRT212862	hsa-miR-30b-5p	PAR-CLIP	22100165
MIRT212858	hsa-miR-30a-5p	PAR-CLIP	22100165
MIRT212864	hsa-miR-30e-5p	PAR-CLIP	22100165
MIRT212859	hsa-miR-30c-5p	PAR-CLIP	22100165
MIRT212861	hsa-miR-200b-3p	PAR-CLIP	22100165
MIRT212863	hsa-miR-200c-3p	PAR-CLIP	22100165
MIRT212865	hsa-miR-429	PAR-CLIP	22100165
MIRT448666	hsa-miR-8084	PAR-CLIP	22100165
MIRT448665	hsa-miR-1183	PAR-CLIP	22100165
MIRT212867	hsa-miR-3607-3p	PAR-CLIP	22100165
MIRT448664	hsa-miR-183-3p	PAR-CLIP	22100165
MIRT448663	hsa-miR-4452	PAR-CLIP	22100165
MIRT714966	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT714965	hsa-miR-4753-3p	HITS-CLIP	19536157
MIRT714964	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT714963	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT714962	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT212860	hsa-miR-30d-5p	PAR-CLIP	22100165
MIRT212862	hsa-miR-30b-5p	PAR-CLIP	22100165
MIRT212858	hsa-miR-30a-5p	PAR-CLIP	22100165
MIRT212864	hsa-miR-30e-5p	PAR-CLIP	22100165
MIRT212859	hsa-miR-30c-5p	PAR-CLIP	22100165
MIRT212861	hsa-miR-200b-3p	PAR-CLIP	22100165
MIRT212863	hsa-miR-200c-3p	PAR-CLIP	22100165
MIRT212865	hsa-miR-429	PAR-CLIP	22100165
MIRT448666	hsa-miR-8084	PAR-CLIP	22100165
MIRT448665	hsa-miR-1183	PAR-CLIP	22100165
MIRT212867	hsa-miR-3607-3p	PAR-CLIP	22100165
MIRT448664	hsa-miR-183-3p	PAR-CLIP	22100165
MIRT448663	hsa-miR-4452	PAR-CLIP	22100165
MIRT212860	hsa-miR-30d-5p	PAR-CLIP	22100165
MIRT212862	hsa-miR-30b-5p	PAR-CLIP	22100165
MIRT212858	hsa-miR-30a-5p	PAR-CLIP	22100165
MIRT212864	hsa-miR-30e-5p	PAR-CLIP	22100165
MIRT212859	hsa-miR-30c-5p	PAR-CLIP	22100165
MIRT212861	hsa-miR-200b-3p	PAR-CLIP	22100165
MIRT212863	hsa-miR-200c-3p	PAR-CLIP	22100165
MIRT212865	hsa-miR-429	PAR-CLIP	22100165
MIRT448666	hsa-miR-8084	PAR-CLIP	22100165
MIRT448665	hsa-miR-1183	PAR-CLIP	22100165
MIRT212867	hsa-miR-3607-3p	PAR-CLIP	22100165
MIRT448664	hsa-miR-183-3p	PAR-CLIP	22100165
MIRT448663	hsa-miR-4452	PAR-CLIP	22100165
MIRT1171015	hsa-miR-1229	CLIP-seq
MIRT1171016	hsa-miR-124	CLIP-seq
MIRT1171017	hsa-miR-1253	CLIP-seq
MIRT1171018	hsa-miR-128	CLIP-seq
MIRT1171019	hsa-miR-1283	CLIP-seq
MIRT1171020	hsa-miR-1324	CLIP-seq
MIRT1171021	hsa-miR-205	CLIP-seq
MIRT1171022	hsa-miR-217	CLIP-seq
MIRT1171023	hsa-miR-22	CLIP-seq
MIRT1171024	hsa-miR-2278	CLIP-seq
MIRT1171025	hsa-miR-23a	CLIP-seq
MIRT1171026	hsa-miR-23b	CLIP-seq
MIRT1171027	hsa-miR-23c	CLIP-seq
MIRT1171028	hsa-miR-27a	CLIP-seq
MIRT1171029	hsa-miR-27b	CLIP-seq
MIRT1171030	hsa-miR-3136-5p	CLIP-seq
MIRT1171031	hsa-miR-3143	CLIP-seq
MIRT1171032	hsa-miR-3168	CLIP-seq
MIRT1171033	hsa-miR-33a	CLIP-seq
MIRT1171034	hsa-miR-33b	CLIP-seq
MIRT1171035	hsa-miR-342-3p	CLIP-seq
MIRT1171036	hsa-miR-3682-5p	CLIP-seq
MIRT1171037	hsa-miR-3714	CLIP-seq
MIRT1171038	hsa-miR-3910	CLIP-seq
MIRT1171039	hsa-miR-4263	CLIP-seq
MIRT1171040	hsa-miR-4269	CLIP-seq
MIRT1171041	hsa-miR-4277	CLIP-seq
MIRT1171042	hsa-miR-4418	CLIP-seq
MIRT1171043	hsa-miR-4438	CLIP-seq
MIRT1171044	hsa-miR-4439	CLIP-seq
MIRT1171045	hsa-miR-4461	CLIP-seq
MIRT1171046	hsa-miR-4477b	CLIP-seq
MIRT1171047	hsa-miR-4495	CLIP-seq
MIRT1171048	hsa-miR-4513	CLIP-seq
MIRT1171049	hsa-miR-4517	CLIP-seq
MIRT1171050	hsa-miR-4637	CLIP-seq
MIRT1171051	hsa-miR-4666-5p	CLIP-seq
MIRT1171052	hsa-miR-4680-3p	CLIP-seq
MIRT1171053	hsa-miR-4699-3p	CLIP-seq
MIRT1171054	hsa-miR-4709-3p	CLIP-seq
MIRT1171055	hsa-miR-4735-5p	CLIP-seq
MIRT1171056	hsa-miR-4760-3p	CLIP-seq
MIRT1171057	hsa-miR-4766-5p	CLIP-seq
MIRT1171058	hsa-miR-4775	CLIP-seq
MIRT1171059	hsa-miR-4777-5p	CLIP-seq
MIRT1171060	hsa-miR-4789-5p	CLIP-seq
MIRT1171061	hsa-miR-485-3p	CLIP-seq
MIRT1171062	hsa-miR-496	CLIP-seq
MIRT1171063	hsa-miR-506	CLIP-seq
MIRT1171064	hsa-miR-509-3-5p	CLIP-seq
MIRT1171065	hsa-miR-5095	CLIP-seq
MIRT1171066	hsa-miR-509-5p	CLIP-seq
MIRT1171067	hsa-miR-518d-5p	CLIP-seq
MIRT1171068	hsa-miR-519b-5p	CLIP-seq
MIRT1171069	hsa-miR-519c-5p	CLIP-seq
MIRT1171070	hsa-miR-520c-5p	CLIP-seq
MIRT1171071	hsa-miR-526a	CLIP-seq
MIRT1171072	hsa-miR-543	CLIP-seq
MIRT1171073	hsa-miR-548a-5p	CLIP-seq
MIRT1171074	hsa-miR-548ab	CLIP-seq
MIRT1171075	hsa-miR-548ak	CLIP-seq
MIRT1171076	hsa-miR-548b-5p	CLIP-seq
MIRT1171077	hsa-miR-548c-3p	CLIP-seq
MIRT1171078	hsa-miR-548c-5p	CLIP-seq
MIRT1171079	hsa-miR-548d-5p	CLIP-seq
MIRT1171080	hsa-miR-548h	CLIP-seq
MIRT1171081	hsa-miR-548i	CLIP-seq
MIRT1171082	hsa-miR-548j	CLIP-seq
MIRT1171083	hsa-miR-548n	CLIP-seq
MIRT1171084	hsa-miR-548t	CLIP-seq
MIRT1171085	hsa-miR-548w	CLIP-seq
MIRT1171086	hsa-miR-548y	CLIP-seq
MIRT1171087	hsa-miR-559	CLIP-seq
MIRT1171088	hsa-miR-562	CLIP-seq
MIRT1171089	hsa-miR-576-5p	CLIP-seq
MIRT1171090	hsa-miR-590-3p	CLIP-seq
MIRT1171091	hsa-miR-653	CLIP-seq
MIRT1171092	hsa-miR-934	CLIP-seq
MIRT1171093	hsa-miR-943	CLIP-seq
MIRT2049318	hsa-miR-1178	CLIP-seq
MIRT2049319	hsa-miR-1200	CLIP-seq
MIRT1171016	hsa-miR-124	CLIP-seq
MIRT2049320	hsa-miR-1299	CLIP-seq
MIRT2049321	hsa-miR-150	CLIP-seq
MIRT2049322	hsa-miR-1915	CLIP-seq
MIRT1171024	hsa-miR-2278	CLIP-seq
MIRT2049323	hsa-miR-3074-5p	CLIP-seq
MIRT2049324	hsa-miR-3148	CLIP-seq
MIRT2049325	hsa-miR-3194-3p	CLIP-seq
MIRT2049326	hsa-miR-330-3p	CLIP-seq
MIRT1171033	hsa-miR-33a	CLIP-seq
MIRT1171034	hsa-miR-33b	CLIP-seq
MIRT1171035	hsa-miR-342-3p	CLIP-seq
MIRT2049327	hsa-miR-3614-5p	CLIP-seq
MIRT2049328	hsa-miR-3650	CLIP-seq
MIRT2049329	hsa-miR-3688-3p	CLIP-seq
MIRT1171037	hsa-miR-3714	CLIP-seq
MIRT2049330	hsa-miR-371-5p	CLIP-seq
MIRT2049331	hsa-miR-371b-5p	CLIP-seq
MIRT1171038	hsa-miR-3910	CLIP-seq
MIRT2049332	hsa-miR-3929	CLIP-seq
MIRT2049333	hsa-miR-3978	CLIP-seq
MIRT1171040	hsa-miR-4269	CLIP-seq
MIRT2049334	hsa-miR-4324	CLIP-seq
MIRT2049335	hsa-miR-4419b	CLIP-seq
MIRT1171043	hsa-miR-4438	CLIP-seq
MIRT1171046	hsa-miR-4477b	CLIP-seq
MIRT2049336	hsa-miR-4478	CLIP-seq
MIRT2049337	hsa-miR-4503	CLIP-seq
MIRT1171050	hsa-miR-4637	CLIP-seq
MIRT2049338	hsa-miR-4682	CLIP-seq
MIRT2049339	hsa-miR-4695-3p	CLIP-seq
MIRT2049340	hsa-miR-4719	CLIP-seq
MIRT2049341	hsa-miR-4726-3p	CLIP-seq
MIRT1171055	hsa-miR-4735-5p	CLIP-seq
MIRT2049342	hsa-miR-4772-3p	CLIP-seq
MIRT1171058	hsa-miR-4775	CLIP-seq
MIRT1171063	hsa-miR-506	CLIP-seq
MIRT1171065	hsa-miR-5095	CLIP-seq
MIRT2049343	hsa-miR-544b	CLIP-seq
MIRT1171077	hsa-miR-548c-3p	CLIP-seq
MIRT2049344	hsa-miR-561	CLIP-seq
MIRT1171090	hsa-miR-590-3p	CLIP-seq
MIRT2049345	hsa-miR-875-3p	CLIP-seq
MIRT2049346	hsa-miR-875-5p	CLIP-seq
MIRT2049347	hsa-miR-890	CLIP-seq
MIRT2278332	hsa-miR-106a	CLIP-seq
MIRT2278333	hsa-miR-106b	CLIP-seq
MIRT2278334	hsa-miR-1234	CLIP-seq
MIRT1171016	hsa-miR-124	CLIP-seq
MIRT2278335	hsa-miR-1265	CLIP-seq
MIRT2049321	hsa-miR-150	CLIP-seq
MIRT2278336	hsa-miR-17	CLIP-seq
MIRT2049322	hsa-miR-1915	CLIP-seq
MIRT2278337	hsa-miR-197	CLIP-seq
MIRT2278338	hsa-miR-1976	CLIP-seq
MIRT2278339	hsa-miR-20a	CLIP-seq
MIRT2278340	hsa-miR-20b	CLIP-seq
MIRT2278341	hsa-miR-25	CLIP-seq
MIRT2278342	hsa-miR-302a	CLIP-seq
MIRT2278343	hsa-miR-302b	CLIP-seq
MIRT2278344	hsa-miR-302c	CLIP-seq
MIRT2278345	hsa-miR-302d	CLIP-seq
MIRT2278346	hsa-miR-302e	CLIP-seq
MIRT2049324	hsa-miR-3148	CLIP-seq
MIRT2049325	hsa-miR-3194-3p	CLIP-seq
MIRT2278347	hsa-miR-32	CLIP-seq
MIRT2049326	hsa-miR-330-3p	CLIP-seq
MIRT2049327	hsa-miR-3614-5p	CLIP-seq
MIRT2278348	hsa-miR-363	CLIP-seq
MIRT2278349	hsa-miR-367	CLIP-seq
MIRT2049329	hsa-miR-3688-3p	CLIP-seq
MIRT1171037	hsa-miR-3714	CLIP-seq
MIRT2049331	hsa-miR-371b-5p	CLIP-seq
MIRT2278350	hsa-miR-372	CLIP-seq
MIRT2278351	hsa-miR-373	CLIP-seq
MIRT1171038	hsa-miR-3910	CLIP-seq
MIRT2049332	hsa-miR-3929	CLIP-seq
MIRT2278352	hsa-miR-3937	CLIP-seq
MIRT2049333	hsa-miR-3978	CLIP-seq
MIRT2278353	hsa-miR-412	CLIP-seq
MIRT1171040	hsa-miR-4269	CLIP-seq
MIRT2278354	hsa-miR-4279	CLIP-seq
MIRT2278355	hsa-miR-4282	CLIP-seq
MIRT2278356	hsa-miR-4317	CLIP-seq
MIRT2049335	hsa-miR-4419b	CLIP-seq
MIRT1171043	hsa-miR-4438	CLIP-seq
MIRT2278357	hsa-miR-4450	CLIP-seq
MIRT2049336	hsa-miR-4478	CLIP-seq
MIRT2049337	hsa-miR-4503	CLIP-seq
MIRT1171050	hsa-miR-4637	CLIP-seq
MIRT2278358	hsa-miR-4640-5p	CLIP-seq
MIRT2278359	hsa-miR-4701-5p	CLIP-seq
MIRT2278360	hsa-miR-4716-5p	CLIP-seq
MIRT2278361	hsa-miR-4722-3p	CLIP-seq
MIRT2049341	hsa-miR-4726-3p	CLIP-seq
MIRT2278362	hsa-miR-4726-5p	CLIP-seq
MIRT2278363	hsa-miR-4731-5p	CLIP-seq
MIRT1171055	hsa-miR-4735-5p	CLIP-seq
MIRT1171056	hsa-miR-4760-3p	CLIP-seq
MIRT1171058	hsa-miR-4775	CLIP-seq
MIRT2278364	hsa-miR-4781-3p	CLIP-seq
MIRT1171063	hsa-miR-506	CLIP-seq
MIRT1171065	hsa-miR-5095	CLIP-seq
MIRT2278365	hsa-miR-512-3p	CLIP-seq
MIRT2278366	hsa-miR-513a-3p	CLIP-seq
MIRT2278367	hsa-miR-515-5p	CLIP-seq
MIRT2278368	hsa-miR-519d	CLIP-seq
MIRT2278369	hsa-miR-520a-3p	CLIP-seq
MIRT2278370	hsa-miR-520b	CLIP-seq
MIRT2278371	hsa-miR-520c-3p	CLIP-seq
MIRT2278372	hsa-miR-520d-3p	CLIP-seq
MIRT2278373	hsa-miR-520e	CLIP-seq
MIRT2278374	hsa-miR-520g	CLIP-seq
MIRT2278375	hsa-miR-520h	CLIP-seq
MIRT2278376	hsa-miR-542-5p	CLIP-seq
MIRT1171088	hsa-miR-562	CLIP-seq
MIRT2278377	hsa-miR-588	CLIP-seq
MIRT1171090	hsa-miR-590-3p	CLIP-seq
MIRT2049347	hsa-miR-890	CLIP-seq
MIRT2278378	hsa-miR-92a	CLIP-seq
MIRT2278379	hsa-miR-92b	CLIP-seq
MIRT2278380	hsa-miR-93	CLIP-seq
MIRT2278342	hsa-miR-302a	CLIP-seq
MIRT2278343	hsa-miR-302b	CLIP-seq
MIRT2278344	hsa-miR-302c	CLIP-seq
MIRT2278345	hsa-miR-302d	CLIP-seq
MIRT2278346	hsa-miR-302e	CLIP-seq
MIRT2278350	hsa-miR-372	CLIP-seq
MIRT2278351	hsa-miR-373	CLIP-seq
MIRT2278363	hsa-miR-4731-5p	CLIP-seq
MIRT2049342	hsa-miR-4772-3p	CLIP-seq
MIRT2278365	hsa-miR-512-3p	CLIP-seq
MIRT2278369	hsa-miR-520a-3p	CLIP-seq
MIRT2278370	hsa-miR-520b	CLIP-seq
MIRT2278371	hsa-miR-520c-3p	CLIP-seq
MIRT2278372	hsa-miR-520d-3p	CLIP-seq
MIRT2278373	hsa-miR-520e	CLIP-seq
MIRT2438832	hsa-miR-183	CLIP-seq
MIRT2438833	hsa-miR-4422	CLIP-seq
MIRT2438834	hsa-miR-4470	CLIP-seq
MIRT2049322	hsa-miR-1915	CLIP-seq
MIRT2049332	hsa-miR-3929	CLIP-seq
MIRT2454756	hsa-miR-3942-5p	CLIP-seq
MIRT2049335	hsa-miR-4419b	CLIP-seq
MIRT2049336	hsa-miR-4478	CLIP-seq
MIRT1171047	hsa-miR-4495	CLIP-seq
MIRT2049337	hsa-miR-4503	CLIP-seq
MIRT1171051	hsa-miR-4666-5p	CLIP-seq
MIRT2454757	hsa-miR-4703-5p	CLIP-seq
MIRT2049341	hsa-miR-4726-3p	CLIP-seq
MIRT1171077	hsa-miR-548c-3p	CLIP-seq
MIRT2465682	hsa-miR-3921	CLIP-seq
MIRT2454756	hsa-miR-3942-5p	CLIP-seq
MIRT1171047	hsa-miR-4495	CLIP-seq
MIRT2465683	hsa-miR-4653-5p	CLIP-seq
MIRT1171051	hsa-miR-4666-5p	CLIP-seq
MIRT2454757	hsa-miR-4703-5p	CLIP-seq
MIRT1171057	hsa-miR-4766-5p	CLIP-seq
MIRT1171077	hsa-miR-548c-3p	CLIP-seq
MIRT2465684	hsa-miR-570	CLIP-seq
MIRT2576677	hsa-miR-3149	CLIP-seq
MIRT2049328	hsa-miR-3650	CLIP-seq
MIRT2049332	hsa-miR-3929	CLIP-seq
MIRT2576678	hsa-miR-3976	CLIP-seq
MIRT1171040	hsa-miR-4269	CLIP-seq
MIRT2049335	hsa-miR-4419b	CLIP-seq
MIRT1171043	hsa-miR-4438	CLIP-seq
MIRT2049336	hsa-miR-4478	CLIP-seq
MIRT1171055	hsa-miR-4735-5p	CLIP-seq
MIRT1171058	hsa-miR-4775	CLIP-seq
MIRT1171065	hsa-miR-5095	CLIP-seq
MIRT1171090	hsa-miR-590-3p	CLIP-seq
MIRT2576679	hsa-miR-633	CLIP-seq
MIRT2576677	hsa-miR-3149	CLIP-seq
MIRT2049328	hsa-miR-3650	CLIP-seq
MIRT2465682	hsa-miR-3921	CLIP-seq
MIRT2049332	hsa-miR-3929	CLIP-seq
MIRT1171040	hsa-miR-4269	CLIP-seq
MIRT2049335	hsa-miR-4419b	CLIP-seq
MIRT1171043	hsa-miR-4438	CLIP-seq
MIRT2049336	hsa-miR-4478	CLIP-seq
MIRT2465683	hsa-miR-4653-5p	CLIP-seq
MIRT1171055	hsa-miR-4735-5p	CLIP-seq
MIRT1171057	hsa-miR-4766-5p	CLIP-seq
MIRT1171058	hsa-miR-4775	CLIP-seq
MIRT1171065	hsa-miR-5095	CLIP-seq
MIRT2465684	hsa-miR-570	CLIP-seq
MIRT1171090	hsa-miR-590-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004519	Function	Endonuclease activity	IBA
GO:0004519	Function	Endonuclease activity	IDA	12730195
GO:0004520	Function	DNA endonuclease activity	IDA	12730195
GO:0005515	Function	Protein binding	IPI	12730195
GO:0005524	Function	ATP binding	IDA	12730195
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0006259	Process	DNA metabolic process	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0043130	Function	Ubiquitin binding	IEA
GO:0046404	Function	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	IDA	12730195

Other IDs

• MIM: 619139
• HGNC: 29851
• e!Ensembl: ENSG00000078177

Protein

• UniProt ID: Q86UW6
• Protein name: NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein)
• Protein function: Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination.
• PDB: 2D9I, 2VKC, 3BHB, 3FAU
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13671	AAA_33	442 → 576		Domain
  PF08590	DUF1771	1619 → 1682	Domain of unknown function (DUF1771)	Domain
  PF01713	Smr	1691 → 1767	Smr domain	Family

• Sequence:

  MPRRRKNLGGNPFRKTANPKEVVVSSVASREEPTTTLPSMGETKVDQEELFTSISEIFSD
  LDPDVVYLMLSECDFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKR
  PEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFI
  NPDSSNMTPIFSTQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYP
  EDSLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASEPQACLNLPGL
  DLPGTGGDQKSTRVSDVFLPSEGFNFKPHKHPELPTKGKDVSYCPVLAPLPLLLPPPPPP
  PMWNPMIPAFDLFQGNHGFVAPVVTTAAHWRSVNYTFPPSVISHTSPTKVWRNKDGTSAY
  QVQETPVSQVVRKKTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYING
  QYQFDVKYLGEAHEWNQNRAKEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFR
  EPDTWWKFKPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYS
  CEDRSTSPRDDEDIISEKEENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNK
  RRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTDTDSSM
  ERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSKSTLEKFP
  RHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTDCVQQ
  RGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRM
  PKTGLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLLSEMTCES
  QTCLSKKSHGQHTSLPLTFTNSAPTVSGVVEPQTLAECQEQMPKRDPGKEVGMCTQTEPQ
  DFALLWKIEKNKISISDSIKVLTGRLDGFKPKVFNINTKSDVQEAIPYRVMYDKSTFVEE
  SELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFEN
  FQKSCDGSQIGPFSLGLNLKEIISQRGTLENSNSPVPEFSHGIGISNADSQSTCDAERGN
  SEQAEMRAVTPENHESMTSIFPSAAVGLKNNNDILPNSQEELLYSSKQSFPGILKATTPK
  DMSETEKNLVVTETGDNIHSPSHFSDIFNFVSSTSNLELNEEIYFTDSLEIKRNENFPKD
  YVKFSDEEEFMNEDEKEMKEILMAGSSLSAGVSGEDKTEILNPTPAMAKSLTIDCLELAL
  PPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGK
  FMQDPSLVGHTGLDNPEQKSSQRTGKKLLKTLTASEMLPLLDHWNTQTKKVSLREIMSEE
  IALQEKHNLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLN
  CVLEGDPVKTVVAQEFVHQNENVTSHTGQKSKEKKPKKLKETEETPSELSFQDFEYPDYD
  DYRAEAFLHQQKRMECYSKAKEAYRIGKKNVATFYAQQGTLHEQKMKEANHLAAIEIFEK
  VNASLLPQNVLDLHGLHVDEALEHLMRVLEKKTEEFKQNGGKPYLSVITGRGNHSQGGVA
  RIKPAVIKYLISHSFRFSEIKPGCLKVMLK

• Sequence length: 1770

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MALIGNANT EPITHELIAL TUMOR OF OVARY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE SCLEROSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Cleft Palate	Cleft palate	Pubtator	28425186	Stimulate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	17626640		★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	17626640	Associate	★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Neoplasms	Nasopharyngeal carcinoma	Pubtator	17626640	Associate	★☆☆☆☆ Found in Text Mining only