DENND4C (DENN domain containing 4C)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 55667 |
| Gene name | DENN domain containing 4C |
| Gene symbol | DENND4C |
| Synonyms (NCBI Gene) |
C9orf55C9orf55BRAB10GEFbA513M16.3
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| Chromosome | 9 |
| Chromosome location | 9p22.1 |
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miRNA
miRNA information provided by mirtarbase database.
724
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
24
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q5VZ89 | ||||||||||||||||||||
| Protein name | DENN domain-containing protein 4C | ||||||||||||||||||||
| Protein function | Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery t | ||||||||||||||||||||
| PDB | 8VOD | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1909 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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