Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	55631
Gene name	Leucine rich repeat containing 40
Gene symbol	LRRC40
Synonyms (NCBI Gene)	dJ677H15.1
Chromosome	1
Chromosome location	1p31.1

173

Show/Hide all (173)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016325	hsa-miR-193b-3p	Microarray	20304954
MIRT016662	hsa-miR-425-5p	Sequencing	20371350
MIRT020510	hsa-miR-155-5p	Proteomics	18668040
MIRT021873	hsa-miR-128-3p	Microarray	17612493
MIRT025256	hsa-miR-34a-5p	Proteomics	21566225
MIRT028855	hsa-miR-26b-5p	Microarray	19088304
MIRT032216	hsa-let-7b-5p	Proteomics	18668040
MIRT687625	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT687624	hsa-miR-4796-5p	HITS-CLIP	23313552
MIRT687623	hsa-miR-4711-3p	HITS-CLIP	23313552
MIRT656613	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT687622	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT687621	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT656614	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT656613	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT656612	hsa-miR-889-3p	HITS-CLIP	23824327
MIRT656610	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT613982	hsa-miR-4742-5p	HITS-CLIP	23824327
MIRT639394	hsa-miR-4269	HITS-CLIP	23824327
MIRT639393	hsa-miR-6715b-5p	HITS-CLIP	23824327
MIRT639392	hsa-miR-4514	HITS-CLIP	23824327
MIRT639391	hsa-miR-4692	HITS-CLIP	23824327
MIRT613981	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT613980	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT613978	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613977	hsa-miR-507	HITS-CLIP	23824327
MIRT613976	hsa-miR-557	HITS-CLIP	23824327
MIRT613975	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613974	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT613982	hsa-miR-4742-5p	HITS-CLIP	23824327
MIRT613981	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT613980	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT613979	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT613978	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613977	hsa-miR-507	HITS-CLIP	23824327
MIRT613976	hsa-miR-557	HITS-CLIP	23824327
MIRT613975	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613974	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT497412	hsa-miR-124-3p	PAR-CLIP	22291592
MIRT497411	hsa-miR-506-3p	PAR-CLIP	22291592
MIRT497410	hsa-miR-452-3p	PAR-CLIP	22291592
MIRT497409	hsa-miR-3161	PAR-CLIP	22291592
MIRT497408	hsa-miR-599	PAR-CLIP	22291592
MIRT441817	hsa-miR-3133	PAR-CLIP	22100165
MIRT687622	hsa-miR-190a-3p	HITS-CLIP	27418678
MIRT687622	hsa-miR-190a-3p	HITS-CLIP	27418678
MIRT687622	hsa-miR-190a-3p	HITS-CLIP	27418678
MIRT687623	hsa-miR-4711-3p	HITS-CLIP	27418678
MIRT687623	hsa-miR-4711-3p	HITS-CLIP	27418678
MIRT687623	hsa-miR-4711-3p	HITS-CLIP	27418678
MIRT687624	hsa-miR-4796-5p	HITS-CLIP	27418678
MIRT687624	hsa-miR-4796-5p	HITS-CLIP	27418678
MIRT687624	hsa-miR-4796-5p	HITS-CLIP	27418678
MIRT687625	hsa-miR-5011-5p	HITS-CLIP	27418678
MIRT687625	hsa-miR-5011-5p	HITS-CLIP	27418678
MIRT687621	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT687621	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT687621	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT656613	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT656613	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT656613	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT687625	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT687624	hsa-miR-4796-5p	HITS-CLIP	23313552
MIRT687623	hsa-miR-4711-3p	HITS-CLIP	23313552
MIRT656613	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT687622	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT687621	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT656614	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT656613	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT656612	hsa-miR-889-3p	HITS-CLIP	23824327
MIRT656610	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT613982	hsa-miR-4742-5p	HITS-CLIP	23824327
MIRT639394	hsa-miR-4269	HITS-CLIP	23824327
MIRT639393	hsa-miR-6715b-5p	HITS-CLIP	23824327
MIRT639392	hsa-miR-4514	HITS-CLIP	23824327
MIRT639391	hsa-miR-4692	HITS-CLIP	23824327
MIRT613981	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT613980	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT613978	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613977	hsa-miR-507	HITS-CLIP	23824327
MIRT613976	hsa-miR-557	HITS-CLIP	23824327
MIRT613975	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613974	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT613982	hsa-miR-4742-5p	HITS-CLIP	23824327
MIRT613981	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT613980	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT613979	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT613978	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613977	hsa-miR-507	HITS-CLIP	23824327
MIRT613976	hsa-miR-557	HITS-CLIP	23824327
MIRT613975	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613974	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT497412	hsa-miR-124-3p	PAR-CLIP	22291592
MIRT497411	hsa-miR-506-3p	PAR-CLIP	22291592
MIRT497410	hsa-miR-452-3p	PAR-CLIP	22291592
MIRT497409	hsa-miR-3161	PAR-CLIP	22291592
MIRT497408	hsa-miR-599	PAR-CLIP	22291592
MIRT441817	hsa-miR-3133	PAR-CLIP	22100165
MIRT1119598	hsa-miR-142-5p	CLIP-seq
MIRT1119599	hsa-miR-193a-3p	CLIP-seq
MIRT1119600	hsa-miR-193b	CLIP-seq
MIRT1119601	hsa-miR-3136-3p	CLIP-seq
MIRT1119602	hsa-miR-3153	CLIP-seq
MIRT1119603	hsa-miR-340	CLIP-seq
MIRT1119604	hsa-miR-34a	CLIP-seq
MIRT1119605	hsa-miR-34c-5p	CLIP-seq
MIRT1119606	hsa-miR-369-3p	CLIP-seq
MIRT1119607	hsa-miR-374c	CLIP-seq
MIRT1119608	hsa-miR-4422	CLIP-seq
MIRT1119609	hsa-miR-449a	CLIP-seq
MIRT1119610	hsa-miR-449b	CLIP-seq
MIRT1119611	hsa-miR-4646-5p	CLIP-seq
MIRT1119612	hsa-miR-4668-5p	CLIP-seq
MIRT1119613	hsa-miR-4699-3p	CLIP-seq
MIRT1119614	hsa-miR-655	CLIP-seq
MIRT1119615	hsa-miR-892b	CLIP-seq
MIRT2033796	hsa-miR-374a	CLIP-seq
MIRT2033797	hsa-miR-374b	CLIP-seq
MIRT2033798	hsa-miR-595	CLIP-seq
MIRT2033799	hsa-miR-633	CLIP-seq
MIRT2264214	hsa-miR-1264	CLIP-seq
MIRT2264215	hsa-miR-889	CLIP-seq
MIRT1119602	hsa-miR-3153	CLIP-seq
MIRT2430852	hsa-miR-4275	CLIP-seq
MIRT1119611	hsa-miR-4646-5p	CLIP-seq
MIRT1119612	hsa-miR-4668-5p	CLIP-seq
MIRT2264214	hsa-miR-1264	CLIP-seq
MIRT2563322	hsa-miR-1279	CLIP-seq
MIRT2563323	hsa-miR-144	CLIP-seq
MIRT2563324	hsa-miR-2681	CLIP-seq
MIRT2563325	hsa-miR-3065-5p	CLIP-seq
MIRT1119601	hsa-miR-3136-3p	CLIP-seq
MIRT2563326	hsa-miR-3653	CLIP-seq
MIRT2563327	hsa-miR-376c	CLIP-seq
MIRT2563328	hsa-miR-421	CLIP-seq
MIRT2563329	hsa-miR-4272	CLIP-seq
MIRT2563330	hsa-miR-4662a-5p	CLIP-seq
MIRT2563331	hsa-miR-4719	CLIP-seq
MIRT2563332	hsa-miR-4738-3p	CLIP-seq
MIRT2563333	hsa-miR-4760-3p	CLIP-seq
MIRT2563334	hsa-miR-4773	CLIP-seq
MIRT2563335	hsa-miR-4775	CLIP-seq
MIRT2563336	hsa-miR-4794	CLIP-seq
MIRT2563337	hsa-miR-493	CLIP-seq
MIRT2563338	hsa-miR-495	CLIP-seq
MIRT2563339	hsa-miR-548c-3p	CLIP-seq
MIRT2563340	hsa-miR-555	CLIP-seq
MIRT2563341	hsa-miR-579	CLIP-seq
MIRT2563342	hsa-miR-590-3p	CLIP-seq
MIRT2563343	hsa-miR-663b	CLIP-seq
MIRT2563344	hsa-miR-664	CLIP-seq
MIRT2264215	hsa-miR-889	CLIP-seq
MIRT1119615	hsa-miR-892b	CLIP-seq
MIRT2264214	hsa-miR-1264	CLIP-seq
MIRT2563323	hsa-miR-144	CLIP-seq
MIRT2563324	hsa-miR-2681	CLIP-seq
MIRT2563325	hsa-miR-3065-5p	CLIP-seq
MIRT1119601	hsa-miR-3136-3p	CLIP-seq
MIRT2563326	hsa-miR-3653	CLIP-seq
MIRT2563327	hsa-miR-376c	CLIP-seq
MIRT2563328	hsa-miR-421	CLIP-seq
MIRT2563329	hsa-miR-4272	CLIP-seq
MIRT2563330	hsa-miR-4662a-5p	CLIP-seq
MIRT2563331	hsa-miR-4719	CLIP-seq
MIRT2563332	hsa-miR-4738-3p	CLIP-seq
MIRT2563334	hsa-miR-4773	CLIP-seq
MIRT2563335	hsa-miR-4775	CLIP-seq
MIRT2563337	hsa-miR-493	CLIP-seq
MIRT2563338	hsa-miR-495	CLIP-seq
MIRT2563340	hsa-miR-555	CLIP-seq
MIRT2563342	hsa-miR-590-3p	CLIP-seq
MIRT2563343	hsa-miR-663b	CLIP-seq
MIRT2264215	hsa-miR-889	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	28514442, 32296183, 33961781
GO:0016020	Component	Membrane	HDA	19946888
GO:0035556	Process	Intracellular signal transduction	IBA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q9H9A6

Protein name

Leucine-rich repeat-containing protein 40

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13855	LRR_8	82 → 140	Leucine rich repeat	Repeat
PF13855	LRR_8	140 → 186	Leucine rich repeat	Repeat
PF13855	LRR_8	151 → 209	Leucine rich repeat	Repeat
PF13855	LRR_8	201 → 255	Leucine rich repeat	Repeat
PF13855	LRR_8	265 → 324	Leucine rich repeat	Repeat
PF00560	LRR_1	543 → 562	Leucine Rich Repeat	Repeat

Sequence

MSRLKRIAGQDLRAGFKAGGRDCGTSVPQGLLKAARKSGQLNLSGRNLSEVPQCVWRINV
DIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSL
PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD
LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA
GMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNK
LKSVPDEIILLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQE
VLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIHAIITLKILDYSDKQATLIPDEVFD
AVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLR
NNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKM
MENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILEYLRDRI
PT

Sequence length

602

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CORONARY ARTERY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

LRRC40 (leucine rich repeat containing 40)