Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	55531
Gene name	ELMO domain containing 1
Gene symbol	ELMOD1
Synonyms (NCBI Gene)	-
Chromosome	11
Chromosome location	11q22.3

202

Show/Hide all (202)

miRTarBase ID	miRNA	Experiments
MIRT960997	hsa-miR-1193	CLIP-seq
MIRT960998	hsa-miR-1208	CLIP-seq
MIRT960999	hsa-miR-122	CLIP-seq
MIRT961000	hsa-miR-1307	CLIP-seq
MIRT961001	hsa-miR-143	CLIP-seq
MIRT961002	hsa-miR-192	CLIP-seq
MIRT961003	hsa-miR-197	CLIP-seq
MIRT961004	hsa-miR-1976	CLIP-seq
MIRT961005	hsa-miR-215	CLIP-seq
MIRT961006	hsa-miR-2392	CLIP-seq
MIRT961007	hsa-miR-2467-5p	CLIP-seq
MIRT961008	hsa-miR-3135b	CLIP-seq
MIRT961009	hsa-miR-3150a-5p	CLIP-seq
MIRT961010	hsa-miR-3150b-5p	CLIP-seq
MIRT961011	hsa-miR-3187-3p	CLIP-seq
MIRT961012	hsa-miR-3188	CLIP-seq
MIRT961013	hsa-miR-3652	CLIP-seq
MIRT961014	hsa-miR-3975	CLIP-seq
MIRT961015	hsa-miR-411	CLIP-seq
MIRT961016	hsa-miR-4269	CLIP-seq
MIRT961017	hsa-miR-4279	CLIP-seq
MIRT961018	hsa-miR-4284	CLIP-seq
MIRT961019	hsa-miR-4303	CLIP-seq
MIRT961020	hsa-miR-431	CLIP-seq
MIRT961021	hsa-miR-4430	CLIP-seq
MIRT961022	hsa-miR-4435	CLIP-seq
MIRT961023	hsa-miR-4438	CLIP-seq
MIRT961024	hsa-miR-4454	CLIP-seq
MIRT961025	hsa-miR-4532	CLIP-seq
MIRT961026	hsa-miR-4638-5p	CLIP-seq
MIRT961027	hsa-miR-4649-3p	CLIP-seq
MIRT961028	hsa-miR-4695-3p	CLIP-seq
MIRT961029	hsa-miR-4701-5p	CLIP-seq
MIRT961030	hsa-miR-4707-3p	CLIP-seq
MIRT961031	hsa-miR-4716-5p	CLIP-seq
MIRT961032	hsa-miR-4722-3p	CLIP-seq
MIRT961033	hsa-miR-4735-5p	CLIP-seq
MIRT961034	hsa-miR-4740-3p	CLIP-seq
MIRT961035	hsa-miR-4755-3p	CLIP-seq
MIRT961036	hsa-miR-4762-3p	CLIP-seq
MIRT961037	hsa-miR-4775	CLIP-seq
MIRT961038	hsa-miR-4781-3p	CLIP-seq
MIRT961039	hsa-miR-483-5p	CLIP-seq
MIRT961040	hsa-miR-485-3p	CLIP-seq
MIRT961041	hsa-miR-485-5p	CLIP-seq
MIRT961042	hsa-miR-487a	CLIP-seq
MIRT961043	hsa-miR-498	CLIP-seq
MIRT961044	hsa-miR-5095	CLIP-seq
MIRT961045	hsa-miR-5096	CLIP-seq
MIRT961046	hsa-miR-548s	CLIP-seq
MIRT961047	hsa-miR-588	CLIP-seq
MIRT961048	hsa-miR-590-3p	CLIP-seq
MIRT960997	hsa-miR-1193	CLIP-seq
MIRT961002	hsa-miR-192	CLIP-seq
MIRT961003	hsa-miR-197	CLIP-seq
MIRT961049	hsa-miR-203	CLIP-seq
MIRT961005	hsa-miR-215	CLIP-seq
MIRT961006	hsa-miR-2392	CLIP-seq
MIRT961050	hsa-miR-3140-3p	CLIP-seq
MIRT961011	hsa-miR-3187-3p	CLIP-seq
MIRT961022	hsa-miR-4435	CLIP-seq
MIRT961024	hsa-miR-4454	CLIP-seq
MIRT961029	hsa-miR-4701-5p	CLIP-seq
MIRT961030	hsa-miR-4707-3p	CLIP-seq
MIRT961031	hsa-miR-4716-5p	CLIP-seq
MIRT961038	hsa-miR-4781-3p	CLIP-seq
MIRT961045	hsa-miR-5096	CLIP-seq
MIRT961046	hsa-miR-548s	CLIP-seq
MIRT961047	hsa-miR-588	CLIP-seq
MIRT960997	hsa-miR-1193	CLIP-seq
MIRT961002	hsa-miR-192	CLIP-seq
MIRT961003	hsa-miR-197	CLIP-seq
MIRT961005	hsa-miR-215	CLIP-seq
MIRT961006	hsa-miR-2392	CLIP-seq
MIRT961011	hsa-miR-3187-3p	CLIP-seq
MIRT961015	hsa-miR-411	CLIP-seq
MIRT961022	hsa-miR-4435	CLIP-seq
MIRT961024	hsa-miR-4454	CLIP-seq
MIRT961029	hsa-miR-4701-5p	CLIP-seq
MIRT961030	hsa-miR-4707-3p	CLIP-seq
MIRT961031	hsa-miR-4716-5p	CLIP-seq
MIRT961038	hsa-miR-4781-3p	CLIP-seq
MIRT961039	hsa-miR-483-5p	CLIP-seq
MIRT961045	hsa-miR-5096	CLIP-seq
MIRT961046	hsa-miR-548s	CLIP-seq
MIRT961047	hsa-miR-588	CLIP-seq
MIRT960997	hsa-miR-1193	CLIP-seq
MIRT960999	hsa-miR-122	CLIP-seq
MIRT961002	hsa-miR-192	CLIP-seq
MIRT961003	hsa-miR-197	CLIP-seq
MIRT961004	hsa-miR-1976	CLIP-seq
MIRT961049	hsa-miR-203	CLIP-seq
MIRT961005	hsa-miR-215	CLIP-seq
MIRT961006	hsa-miR-2392	CLIP-seq
MIRT961008	hsa-miR-3135b	CLIP-seq
MIRT961011	hsa-miR-3187-3p	CLIP-seq
MIRT961013	hsa-miR-3652	CLIP-seq
MIRT961015	hsa-miR-411	CLIP-seq
MIRT961016	hsa-miR-4269	CLIP-seq
MIRT961017	hsa-miR-4279	CLIP-seq
MIRT961021	hsa-miR-4430	CLIP-seq
MIRT961022	hsa-miR-4435	CLIP-seq
MIRT961023	hsa-miR-4438	CLIP-seq
MIRT961024	hsa-miR-4454	CLIP-seq
MIRT961025	hsa-miR-4532	CLIP-seq
MIRT961028	hsa-miR-4695-3p	CLIP-seq
MIRT961029	hsa-miR-4701-5p	CLIP-seq
MIRT961030	hsa-miR-4707-3p	CLIP-seq
MIRT961031	hsa-miR-4716-5p	CLIP-seq
MIRT961032	hsa-miR-4722-3p	CLIP-seq
MIRT961033	hsa-miR-4735-5p	CLIP-seq
MIRT961034	hsa-miR-4740-3p	CLIP-seq
MIRT961035	hsa-miR-4755-3p	CLIP-seq
MIRT961038	hsa-miR-4781-3p	CLIP-seq
MIRT961039	hsa-miR-483-5p	CLIP-seq
MIRT961043	hsa-miR-498	CLIP-seq
MIRT961044	hsa-miR-5095	CLIP-seq
MIRT961045	hsa-miR-5096	CLIP-seq
MIRT961046	hsa-miR-548s	CLIP-seq
MIRT961047	hsa-miR-588	CLIP-seq
MIRT2219629	hsa-miR-101	CLIP-seq
MIRT2219630	hsa-miR-1273d	CLIP-seq
MIRT2219631	hsa-miR-144	CLIP-seq
MIRT961003	hsa-miR-197	CLIP-seq
MIRT961004	hsa-miR-1976	CLIP-seq
MIRT2219632	hsa-miR-3123	CLIP-seq
MIRT2219633	hsa-miR-3130-5p	CLIP-seq
MIRT2219634	hsa-miR-3925-5p	CLIP-seq
MIRT961015	hsa-miR-411	CLIP-seq
MIRT961016	hsa-miR-4269	CLIP-seq
MIRT961017	hsa-miR-4279	CLIP-seq
MIRT961023	hsa-miR-4438	CLIP-seq
MIRT2219635	hsa-miR-4482	CLIP-seq
MIRT961025	hsa-miR-4532	CLIP-seq
MIRT2219636	hsa-miR-4666-3p	CLIP-seq
MIRT2219637	hsa-miR-4680-3p	CLIP-seq
MIRT961031	hsa-miR-4716-5p	CLIP-seq
MIRT961032	hsa-miR-4722-3p	CLIP-seq
MIRT961033	hsa-miR-4735-5p	CLIP-seq
MIRT961034	hsa-miR-4740-3p	CLIP-seq
MIRT961035	hsa-miR-4755-3p	CLIP-seq
MIRT961037	hsa-miR-4775	CLIP-seq
MIRT961038	hsa-miR-4781-3p	CLIP-seq
MIRT961039	hsa-miR-483-5p	CLIP-seq
MIRT961043	hsa-miR-498	CLIP-seq
MIRT961044	hsa-miR-5095	CLIP-seq
MIRT961045	hsa-miR-5096	CLIP-seq
MIRT2219638	hsa-miR-539	CLIP-seq
MIRT2219639	hsa-miR-582-5p	CLIP-seq
MIRT961048	hsa-miR-590-3p	CLIP-seq
MIRT2219640	hsa-miR-936	CLIP-seq
MIRT960999	hsa-miR-122	CLIP-seq
MIRT961008	hsa-miR-3135b	CLIP-seq
MIRT961013	hsa-miR-3652	CLIP-seq
MIRT961021	hsa-miR-4430	CLIP-seq
MIRT961028	hsa-miR-4695-3p	CLIP-seq
MIRT961035	hsa-miR-4755-3p	CLIP-seq
MIRT960999	hsa-miR-122	CLIP-seq
MIRT961000	hsa-miR-1307	CLIP-seq
MIRT961001	hsa-miR-143	CLIP-seq
MIRT961004	hsa-miR-1976	CLIP-seq
MIRT961008	hsa-miR-3135b	CLIP-seq
MIRT961009	hsa-miR-3150a-5p	CLIP-seq
MIRT961010	hsa-miR-3150b-5p	CLIP-seq
MIRT961013	hsa-miR-3652	CLIP-seq
MIRT961016	hsa-miR-4269	CLIP-seq
MIRT961017	hsa-miR-4279	CLIP-seq
MIRT961020	hsa-miR-431	CLIP-seq
MIRT961021	hsa-miR-4430	CLIP-seq
MIRT961023	hsa-miR-4438	CLIP-seq
MIRT961025	hsa-miR-4532	CLIP-seq
MIRT961026	hsa-miR-4638-5p	CLIP-seq
MIRT961028	hsa-miR-4695-3p	CLIP-seq
MIRT961032	hsa-miR-4722-3p	CLIP-seq
MIRT961034	hsa-miR-4740-3p	CLIP-seq
MIRT961035	hsa-miR-4755-3p	CLIP-seq
MIRT961043	hsa-miR-498	CLIP-seq
MIRT961044	hsa-miR-5095	CLIP-seq
MIRT960999	hsa-miR-122	CLIP-seq
MIRT961000	hsa-miR-1307	CLIP-seq
MIRT961001	hsa-miR-143	CLIP-seq
MIRT961004	hsa-miR-1976	CLIP-seq
MIRT961008	hsa-miR-3135b	CLIP-seq
MIRT961009	hsa-miR-3150a-5p	CLIP-seq
MIRT961010	hsa-miR-3150b-5p	CLIP-seq
MIRT961013	hsa-miR-3652	CLIP-seq
MIRT961016	hsa-miR-4269	CLIP-seq
MIRT961017	hsa-miR-4279	CLIP-seq
MIRT961020	hsa-miR-431	CLIP-seq
MIRT961021	hsa-miR-4430	CLIP-seq
MIRT961023	hsa-miR-4438	CLIP-seq
MIRT961025	hsa-miR-4532	CLIP-seq
MIRT961026	hsa-miR-4638-5p	CLIP-seq
MIRT961028	hsa-miR-4695-3p	CLIP-seq
MIRT961032	hsa-miR-4722-3p	CLIP-seq
MIRT961033	hsa-miR-4735-5p	CLIP-seq
MIRT961034	hsa-miR-4740-3p	CLIP-seq
MIRT961035	hsa-miR-4755-3p	CLIP-seq
MIRT961037	hsa-miR-4775	CLIP-seq
MIRT961043	hsa-miR-498	CLIP-seq
MIRT961044	hsa-miR-5095	CLIP-seq
MIRT961048	hsa-miR-590-3p	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IDA	17452337
GO:0005096	Function	GTPase activator activity	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005929	Component	Cilium	IEA
GO:0008104	Process	Intracellular protein localization	IEA
GO:0015031	Process	Protein transport	IEA
GO:0045202	Component	Synapse	IEA
GO:0060271	Process	Cilium assembly	IEA
GO:0098978	Component	Glutamatergic synapse	IEA

MIM	HGNC	e!Ensembl
615456	25334	ENSG00000110675

Q8N336

Protein name

ELMO domain-containing protein 1

Protein function

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04727	ELMO_CED12	117 → 303	ELMO/CED-12 family	Family

Sequence

MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRD
SKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDVNPQLGISLQACLLQIVGYRNLIADVE
KLRREAYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLG
LYNLQYFAERDATAAQQVLSDSLHPKCRDITKEEISKFSKAEWEKKRMDKAIGYSFAIVG
INITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFN
RVREKFRKRIIKQLQNPDMALCPHFAASEGLINM

Sequence length

334

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CEREBRAL AMYLOID ANGIOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (5)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	31327155		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	35065650	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	31327155		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation	Mental retardation	BEFREE	31327155		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pervasive Development Disorder	Autism spectrum disorder	BEFREE	31327155		★★★★★ ★☆☆☆☆ Found in Text Mining only

ELMOD1 (ELMO domain containing 1)