PPP6C (protein phosphatase 6 catalytic subunit)

Gene

• Entrez ID: 5537
• Gene name: Protein phosphatase 6 catalytic subunit
• Gene symbol: PPP6C
• Synonyms (NCBI Gene): PP6, PP6C
• Chromosome: 9
• Chromosome location: 9q33.3
• Summary: This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X. [provi

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs763733111	G>A	Likely-pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT027236	hsa-miR-103a-3p	Sequencing	20371350
MIRT031938	hsa-miR-16-5p	Proteomics	18668040
MIRT031938	hsa-miR-16-5p	Sequencing	20371350
MIRT049228	hsa-miR-92a-3p	CLASH	23622248
MIRT046636	hsa-miR-222-3p	CLASH	23622248
MIRT546990	hsa-miR-107	PAR-CLIP	21572407
MIRT027236	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT546989	hsa-miR-499a-5p	PAR-CLIP	21572407
MIRT546988	hsa-miR-208a-3p	PAR-CLIP	21572407
MIRT546987	hsa-miR-208b-3p	PAR-CLIP	21572407
MIRT546986	hsa-miR-496	PAR-CLIP	21572407
MIRT546984	hsa-miR-3617-5p	PAR-CLIP	21572407
MIRT546982	hsa-miR-641	PAR-CLIP	21572407
MIRT546983	hsa-miR-4519	PAR-CLIP	21572407
MIRT546981	hsa-miR-4302	PAR-CLIP	21572407
MIRT546980	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT107076	hsa-miR-4477a	PAR-CLIP	21572407
MIRT506054	hsa-miR-218-5p	PAR-CLIP	21572407
MIRT173999	hsa-miR-548as-3p	PAR-CLIP	21572407
MIRT506053	hsa-miR-6732-3p	PAR-CLIP	21572407
MIRT506052	hsa-miR-144-3p	PAR-CLIP	21572407
MIRT555298	hsa-miR-1323	PAR-CLIP	21572407
MIRT555297	hsa-miR-548o-3p	PAR-CLIP	21572407
MIRT506051	hsa-miR-4275	PAR-CLIP	21572407
MIRT506050	hsa-miR-16-1-3p	PAR-CLIP	21572407
MIRT506049	hsa-miR-4502	PAR-CLIP	21572407
MIRT506048	hsa-miR-4480	PAR-CLIP	21572407
MIRT506047	hsa-miR-7158-5p	PAR-CLIP	21572407
MIRT546990	hsa-miR-107	PAR-CLIP	21572407
MIRT027236	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT546989	hsa-miR-499a-5p	PAR-CLIP	21572407
MIRT546988	hsa-miR-208a-3p	PAR-CLIP	21572407
MIRT546987	hsa-miR-208b-3p	PAR-CLIP	21572407
MIRT546986	hsa-miR-496	PAR-CLIP	21572407
MIRT046636	hsa-miR-222-3p	PAR-CLIP	21572407
MIRT546985	hsa-miR-221-3p	PAR-CLIP	21572407
MIRT546984	hsa-miR-3617-5p	PAR-CLIP	21572407
MIRT546982	hsa-miR-641	PAR-CLIP	21572407
MIRT546983	hsa-miR-4519	PAR-CLIP	21572407
MIRT546981	hsa-miR-4302	PAR-CLIP	21572407
MIRT546980	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT107076	hsa-miR-4477a	PAR-CLIP	21572407
MIRT506054	hsa-miR-218-5p	PAR-CLIP	23446348
MIRT173999	hsa-miR-548as-3p	PAR-CLIP	23446348
MIRT506053	hsa-miR-6732-3p	PAR-CLIP	23446348
MIRT506052	hsa-miR-144-3p	PAR-CLIP	23446348
MIRT506051	hsa-miR-4275	PAR-CLIP	23446348
MIRT506050	hsa-miR-16-1-3p	PAR-CLIP	23446348
MIRT506049	hsa-miR-4502	PAR-CLIP	23446348
MIRT506048	hsa-miR-4480	PAR-CLIP	23446348
MIRT506047	hsa-miR-7158-5p	PAR-CLIP	23446348
MIRT439907	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT439906	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT439905	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT439907	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT439906	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT726874	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT726873	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT031938	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT726872	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT726871	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT726870	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT726869	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT726868	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT439905	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT546990	hsa-miR-107	PAR-CLIP	21572407
MIRT027236	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT546989	hsa-miR-499a-5p	PAR-CLIP	21572407
MIRT546988	hsa-miR-208a-3p	PAR-CLIP	21572407
MIRT546987	hsa-miR-208b-3p	PAR-CLIP	21572407
MIRT546986	hsa-miR-496	PAR-CLIP	21572407
MIRT546984	hsa-miR-3617-5p	PAR-CLIP	21572407
MIRT546982	hsa-miR-641	PAR-CLIP	21572407
MIRT546983	hsa-miR-4519	PAR-CLIP	21572407
MIRT546981	hsa-miR-4302	PAR-CLIP	21572407
MIRT546980	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT107076	hsa-miR-4477a	PAR-CLIP	21572407
MIRT506054	hsa-miR-218-5p	PAR-CLIP	21572407
MIRT173999	hsa-miR-548as-3p	PAR-CLIP	21572407
MIRT506053	hsa-miR-6732-3p	PAR-CLIP	21572407
MIRT506052	hsa-miR-144-3p	PAR-CLIP	21572407
MIRT555298	hsa-miR-1323	PAR-CLIP	21572407
MIRT555297	hsa-miR-548o-3p	PAR-CLIP	21572407
MIRT506051	hsa-miR-4275	PAR-CLIP	21572407
MIRT506050	hsa-miR-16-1-3p	PAR-CLIP	21572407
MIRT506049	hsa-miR-4502	PAR-CLIP	21572407
MIRT506048	hsa-miR-4480	PAR-CLIP	21572407
MIRT506047	hsa-miR-7158-5p	PAR-CLIP	21572407
MIRT546990	hsa-miR-107	PAR-CLIP	21572407
MIRT027236	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT546989	hsa-miR-499a-5p	PAR-CLIP	21572407
MIRT546988	hsa-miR-208a-3p	PAR-CLIP	21572407
MIRT546987	hsa-miR-208b-3p	PAR-CLIP	21572407
MIRT546986	hsa-miR-496	PAR-CLIP	21572407
MIRT046636	hsa-miR-222-3p	PAR-CLIP	21572407
MIRT546985	hsa-miR-221-3p	PAR-CLIP	21572407
MIRT546984	hsa-miR-3617-5p	PAR-CLIP	21572407
MIRT546982	hsa-miR-641	PAR-CLIP	21572407
MIRT546983	hsa-miR-4519	PAR-CLIP	21572407
MIRT546981	hsa-miR-4302	PAR-CLIP	21572407
MIRT546980	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT107076	hsa-miR-4477a	PAR-CLIP	21572407
MIRT506054	hsa-miR-218-5p	PAR-CLIP	23446348
MIRT173999	hsa-miR-548as-3p	PAR-CLIP	23446348
MIRT506053	hsa-miR-6732-3p	PAR-CLIP	23446348
MIRT506052	hsa-miR-144-3p	PAR-CLIP	23446348
MIRT506051	hsa-miR-4275	PAR-CLIP	23446348
MIRT506050	hsa-miR-16-1-3p	PAR-CLIP	23446348
MIRT506049	hsa-miR-4502	PAR-CLIP	23446348
MIRT506048	hsa-miR-4480	PAR-CLIP	23446348
MIRT506047	hsa-miR-7158-5p	PAR-CLIP	23446348
MIRT1258600	hsa-miR-1243	CLIP-seq
MIRT1258601	hsa-miR-23a	CLIP-seq
MIRT1258602	hsa-miR-23b	CLIP-seq
MIRT1258603	hsa-miR-23c	CLIP-seq
MIRT1258604	hsa-miR-548g	CLIP-seq
MIRT1258605	hsa-miR-103a	CLIP-seq
MIRT1258606	hsa-miR-106a	CLIP-seq
MIRT1258607	hsa-miR-106b	CLIP-seq
MIRT1258608	hsa-miR-1236	CLIP-seq
MIRT1258600	hsa-miR-1243	CLIP-seq
MIRT1258609	hsa-miR-1264	CLIP-seq
MIRT1258610	hsa-miR-1289	CLIP-seq
MIRT1258611	hsa-miR-1290	CLIP-seq
MIRT1258612	hsa-miR-129-3p	CLIP-seq
MIRT1258613	hsa-miR-1321	CLIP-seq
MIRT1258614	hsa-miR-1343	CLIP-seq
MIRT1258615	hsa-miR-15a	CLIP-seq
MIRT1258616	hsa-miR-15b	CLIP-seq
MIRT1258617	hsa-miR-16	CLIP-seq
MIRT1258618	hsa-miR-17	CLIP-seq
MIRT1258619	hsa-miR-181a	CLIP-seq
MIRT1258620	hsa-miR-181b	CLIP-seq
MIRT1258621	hsa-miR-181c	CLIP-seq
MIRT1258622	hsa-miR-181d	CLIP-seq
MIRT1258623	hsa-miR-1827	CLIP-seq
MIRT1258624	hsa-miR-195	CLIP-seq
MIRT1258625	hsa-miR-1976	CLIP-seq
MIRT1258626	hsa-miR-204	CLIP-seq
MIRT1258627	hsa-miR-208a	CLIP-seq
MIRT1258628	hsa-miR-208b	CLIP-seq
MIRT1258629	hsa-miR-20a	CLIP-seq
MIRT1258630	hsa-miR-20b	CLIP-seq
MIRT1258631	hsa-miR-211	CLIP-seq
MIRT1258632	hsa-miR-2116	CLIP-seq
MIRT1258633	hsa-miR-214	CLIP-seq
MIRT1258634	hsa-miR-221	CLIP-seq
MIRT1258635	hsa-miR-222	CLIP-seq
MIRT1258601	hsa-miR-23a	CLIP-seq
MIRT1258602	hsa-miR-23b	CLIP-seq
MIRT1258603	hsa-miR-23c	CLIP-seq
MIRT1258636	hsa-miR-300	CLIP-seq
MIRT1258637	hsa-miR-302a	CLIP-seq
MIRT1258638	hsa-miR-302b	CLIP-seq
MIRT1258639	hsa-miR-302c	CLIP-seq
MIRT1258640	hsa-miR-302d	CLIP-seq
MIRT1258641	hsa-miR-302e	CLIP-seq
MIRT1258642	hsa-miR-3074-5p	CLIP-seq
MIRT1258643	hsa-miR-31	CLIP-seq
MIRT1258644	hsa-miR-3140-5p	CLIP-seq
MIRT1258645	hsa-miR-3157-5p	CLIP-seq
MIRT1258646	hsa-miR-3162-5p	CLIP-seq
MIRT1258647	hsa-miR-3173-3p	CLIP-seq
MIRT1258648	hsa-miR-3179	CLIP-seq
MIRT1258649	hsa-miR-3192	CLIP-seq
MIRT1258650	hsa-miR-3198	CLIP-seq
MIRT1258651	hsa-miR-335	CLIP-seq
MIRT1258652	hsa-miR-337-3p	CLIP-seq
MIRT1258653	hsa-miR-338-5p	CLIP-seq
MIRT1258654	hsa-miR-3609	CLIP-seq
MIRT1258655	hsa-miR-3616-3p	CLIP-seq
MIRT1258656	hsa-miR-3617	CLIP-seq
MIRT1258657	hsa-miR-3619-5p	CLIP-seq
MIRT1258658	hsa-miR-3652	CLIP-seq
MIRT1258659	hsa-miR-3674	CLIP-seq
MIRT1258660	hsa-miR-3684	CLIP-seq
MIRT1258661	hsa-miR-3690	CLIP-seq
MIRT1258662	hsa-miR-371-5p	CLIP-seq
MIRT1258663	hsa-miR-371b-5p	CLIP-seq
MIRT1258664	hsa-miR-372	CLIP-seq
MIRT1258665	hsa-miR-373	CLIP-seq
MIRT1258666	hsa-miR-374c	CLIP-seq
MIRT1258667	hsa-miR-376c	CLIP-seq
MIRT1258668	hsa-miR-381	CLIP-seq
MIRT1258669	hsa-miR-3926	CLIP-seq
MIRT1258670	hsa-miR-3942-3p	CLIP-seq
MIRT1258671	hsa-miR-3977	CLIP-seq
MIRT1258672	hsa-miR-3978	CLIP-seq
MIRT1258673	hsa-miR-424	CLIP-seq
MIRT1258674	hsa-miR-4254	CLIP-seq
MIRT1258675	hsa-miR-4262	CLIP-seq
MIRT1258676	hsa-miR-4291	CLIP-seq
MIRT1258677	hsa-miR-4294	CLIP-seq
MIRT1258678	hsa-miR-4309	CLIP-seq
MIRT1258679	hsa-miR-4310	CLIP-seq
MIRT1258680	hsa-miR-4427	CLIP-seq
MIRT1258681	hsa-miR-4430	CLIP-seq
MIRT1258682	hsa-miR-4436b-3p	CLIP-seq
MIRT1258683	hsa-miR-4457	CLIP-seq
MIRT1258684	hsa-miR-4505	CLIP-seq
MIRT1258685	hsa-miR-4511	CLIP-seq
MIRT1258686	hsa-miR-451b	CLIP-seq
MIRT1258687	hsa-miR-4641	CLIP-seq
MIRT1258688	hsa-miR-4653-3p	CLIP-seq
MIRT1258689	hsa-miR-4662a-5p	CLIP-seq
MIRT1258690	hsa-miR-4666-3p	CLIP-seq
MIRT1258691	hsa-miR-4686	CLIP-seq
MIRT1258692	hsa-miR-4709-3p	CLIP-seq
MIRT1258693	hsa-miR-4722-3p	CLIP-seq
MIRT1258694	hsa-miR-4732-5p	CLIP-seq
MIRT1258695	hsa-miR-4739	CLIP-seq
MIRT1258696	hsa-miR-4755-5p	CLIP-seq
MIRT1258697	hsa-miR-4756-5p	CLIP-seq
MIRT1258698	hsa-miR-4774-5p	CLIP-seq
MIRT1258699	hsa-miR-4779	CLIP-seq
MIRT1258700	hsa-miR-4796-3p	CLIP-seq
MIRT1258701	hsa-miR-495	CLIP-seq
MIRT1258702	hsa-miR-497	CLIP-seq
MIRT1258703	hsa-miR-499-3p	CLIP-seq
MIRT1258704	hsa-miR-499-5p	CLIP-seq
MIRT1258705	hsa-miR-499a-3p	CLIP-seq
MIRT1258706	hsa-miR-513b	CLIP-seq
MIRT1258707	hsa-miR-513c	CLIP-seq
MIRT1258708	hsa-miR-514b-5p	CLIP-seq
MIRT1258709	hsa-miR-519d	CLIP-seq
MIRT1258710	hsa-miR-520a-3p	CLIP-seq
MIRT1258711	hsa-miR-520b	CLIP-seq
MIRT1258712	hsa-miR-520c-3p	CLIP-seq
MIRT1258713	hsa-miR-520d-3p	CLIP-seq
MIRT1258714	hsa-miR-520e	CLIP-seq
MIRT1258715	hsa-miR-520f	CLIP-seq
MIRT1258716	hsa-miR-520g	CLIP-seq
MIRT1258717	hsa-miR-520h	CLIP-seq
MIRT1258718	hsa-miR-545	CLIP-seq
MIRT1258719	hsa-miR-548ah	CLIP-seq
MIRT1258720	hsa-miR-548an	CLIP-seq
MIRT1258604	hsa-miR-548g	CLIP-seq
MIRT1258721	hsa-miR-548l	CLIP-seq
MIRT1258722	hsa-miR-548n	CLIP-seq
MIRT1258723	hsa-miR-582-3p	CLIP-seq
MIRT1258724	hsa-miR-582-5p	CLIP-seq
MIRT1258725	hsa-miR-607	CLIP-seq
MIRT1258726	hsa-miR-623	CLIP-seq
MIRT1258727	hsa-miR-647	CLIP-seq
MIRT1258728	hsa-miR-655	CLIP-seq
MIRT1258729	hsa-miR-671-3p	CLIP-seq
MIRT1258730	hsa-miR-761	CLIP-seq
MIRT1258731	hsa-miR-802	CLIP-seq
MIRT1258732	hsa-miR-888	CLIP-seq
MIRT1258733	hsa-miR-922	CLIP-seq
MIRT1258734	hsa-miR-93	CLIP-seq
MIRT1258735	hsa-miR-942	CLIP-seq
MIRT1258605	hsa-miR-103a	CLIP-seq
MIRT1258736	hsa-miR-139-5p	CLIP-seq
MIRT1258634	hsa-miR-221	CLIP-seq
MIRT1258635	hsa-miR-222	CLIP-seq
MIRT1258651	hsa-miR-335	CLIP-seq
MIRT1258686	hsa-miR-451b	CLIP-seq
MIRT1258737	hsa-miR-4729	CLIP-seq
MIRT1258605	hsa-miR-103a	CLIP-seq
MIRT1258736	hsa-miR-139-5p	CLIP-seq
MIRT1258637	hsa-miR-302a	CLIP-seq
MIRT1258638	hsa-miR-302b	CLIP-seq
MIRT1258639	hsa-miR-302c	CLIP-seq
MIRT1258640	hsa-miR-302d	CLIP-seq
MIRT1258641	hsa-miR-302e	CLIP-seq
MIRT1258664	hsa-miR-372	CLIP-seq
MIRT1258665	hsa-miR-373	CLIP-seq
MIRT1258679	hsa-miR-4310	CLIP-seq
MIRT1258682	hsa-miR-4436b-3p	CLIP-seq
MIRT2076222	hsa-miR-490-3p	CLIP-seq
MIRT1258707	hsa-miR-513c	CLIP-seq
MIRT1258708	hsa-miR-514b-5p	CLIP-seq
MIRT1258710	hsa-miR-520a-3p	CLIP-seq
MIRT1258711	hsa-miR-520b	CLIP-seq
MIRT1258712	hsa-miR-520c-3p	CLIP-seq
MIRT1258713	hsa-miR-520d-3p	CLIP-seq
MIRT2076223	hsa-miR-520d-5p	CLIP-seq
MIRT1258714	hsa-miR-520e	CLIP-seq
MIRT1258716	hsa-miR-520g	CLIP-seq
MIRT1258717	hsa-miR-520h	CLIP-seq
MIRT2076224	hsa-miR-524-5p	CLIP-seq
MIRT1258721	hsa-miR-548l	CLIP-seq
MIRT1258722	hsa-miR-548n	CLIP-seq
MIRT2076225	hsa-miR-1293	CLIP-seq
MIRT2076226	hsa-miR-1304	CLIP-seq
MIRT2076227	hsa-miR-28-5p	CLIP-seq
MIRT2076228	hsa-miR-3139	CLIP-seq
MIRT2076229	hsa-miR-4314	CLIP-seq
MIRT2076230	hsa-miR-4483	CLIP-seq
MIRT2076231	hsa-miR-4487	CLIP-seq
MIRT2076232	hsa-miR-4793-5p	CLIP-seq
MIRT1258707	hsa-miR-513c	CLIP-seq
MIRT1258708	hsa-miR-514b-5p	CLIP-seq
MIRT2076233	hsa-miR-708	CLIP-seq
MIRT2076234	hsa-miR-876-3p	CLIP-seq
MIRT1258605	hsa-miR-103a	CLIP-seq
MIRT1258623	hsa-miR-1827	CLIP-seq
MIRT1258637	hsa-miR-302a	CLIP-seq
MIRT1258638	hsa-miR-302b	CLIP-seq
MIRT1258639	hsa-miR-302c	CLIP-seq
MIRT1258640	hsa-miR-302d	CLIP-seq
MIRT1258641	hsa-miR-302e	CLIP-seq
MIRT1258664	hsa-miR-372	CLIP-seq
MIRT1258665	hsa-miR-373	CLIP-seq
MIRT1258679	hsa-miR-4310	CLIP-seq
MIRT2302812	hsa-miR-448	CLIP-seq
MIRT2302813	hsa-miR-513a-3p	CLIP-seq
MIRT1258707	hsa-miR-513c	CLIP-seq
MIRT1258708	hsa-miR-514b-5p	CLIP-seq
MIRT1258710	hsa-miR-520a-3p	CLIP-seq
MIRT1258711	hsa-miR-520b	CLIP-seq
MIRT1258712	hsa-miR-520c-3p	CLIP-seq
MIRT1258713	hsa-miR-520d-3p	CLIP-seq
MIRT1258714	hsa-miR-520e	CLIP-seq
MIRT1258718	hsa-miR-545	CLIP-seq
MIRT1258721	hsa-miR-548l	CLIP-seq
MIRT1258722	hsa-miR-548n	CLIP-seq
MIRT2302814	hsa-miR-101	CLIP-seq
MIRT1258605	hsa-miR-103a	CLIP-seq
MIRT2302815	hsa-miR-1273f	CLIP-seq
MIRT2302816	hsa-miR-128	CLIP-seq
MIRT1258610	hsa-miR-1289	CLIP-seq
MIRT1258612	hsa-miR-129-3p	CLIP-seq
MIRT2302817	hsa-miR-1302	CLIP-seq
MIRT2076226	hsa-miR-1304	CLIP-seq
MIRT1258613	hsa-miR-1321	CLIP-seq
MIRT1258623	hsa-miR-1827	CLIP-seq
MIRT1258627	hsa-miR-208a	CLIP-seq
MIRT1258628	hsa-miR-208b	CLIP-seq
MIRT2302818	hsa-miR-224	CLIP-seq
MIRT1258601	hsa-miR-23a	CLIP-seq
MIRT1258602	hsa-miR-23b	CLIP-seq
MIRT1258603	hsa-miR-23c	CLIP-seq
MIRT2302819	hsa-miR-27a	CLIP-seq
MIRT2302820	hsa-miR-27b	CLIP-seq
MIRT1258647	hsa-miR-3173-3p	CLIP-seq
MIRT1258649	hsa-miR-3192	CLIP-seq
MIRT1258650	hsa-miR-3198	CLIP-seq
MIRT2302821	hsa-miR-4270	CLIP-seq
MIRT1258676	hsa-miR-4291	CLIP-seq
MIRT1258677	hsa-miR-4294	CLIP-seq
MIRT2302822	hsa-miR-4298	CLIP-seq
MIRT1258678	hsa-miR-4309	CLIP-seq
MIRT2076229	hsa-miR-4314	CLIP-seq
MIRT1258680	hsa-miR-4427	CLIP-seq
MIRT1258682	hsa-miR-4436b-3p	CLIP-seq
MIRT2302823	hsa-miR-4438	CLIP-seq
MIRT2302824	hsa-miR-4441	CLIP-seq
MIRT2302825	hsa-miR-4528	CLIP-seq
MIRT2302826	hsa-miR-4646-5p	CLIP-seq
MIRT2302827	hsa-miR-4728-5p	CLIP-seq
MIRT1258695	hsa-miR-4739	CLIP-seq
MIRT1258697	hsa-miR-4756-5p	CLIP-seq
MIRT1258701	hsa-miR-495	CLIP-seq
MIRT1258703	hsa-miR-499-3p	CLIP-seq
MIRT1258704	hsa-miR-499-5p	CLIP-seq
MIRT1258705	hsa-miR-499a-3p	CLIP-seq
MIRT2302828	hsa-miR-5095	CLIP-seq
MIRT2302829	hsa-miR-513a-5p	CLIP-seq
MIRT1258707	hsa-miR-513c	CLIP-seq
MIRT1258708	hsa-miR-514b-5p	CLIP-seq
MIRT1258718	hsa-miR-545	CLIP-seq
MIRT2302830	hsa-miR-548c-3p	CLIP-seq
MIRT1258722	hsa-miR-548n	CLIP-seq
MIRT2302831	hsa-miR-548t	CLIP-seq
MIRT1258733	hsa-miR-922	CLIP-seq
MIRT1258605	hsa-miR-103a	CLIP-seq
MIRT2302814	hsa-miR-101	CLIP-seq
MIRT1258605	hsa-miR-103a	CLIP-seq
MIRT2599539	hsa-miR-105	CLIP-seq
MIRT2302816	hsa-miR-128	CLIP-seq
MIRT2076225	hsa-miR-1293	CLIP-seq
MIRT2599540	hsa-miR-1297	CLIP-seq
MIRT2076226	hsa-miR-1304	CLIP-seq
MIRT1258627	hsa-miR-208a	CLIP-seq
MIRT1258628	hsa-miR-208b	CLIP-seq
MIRT1258634	hsa-miR-221	CLIP-seq
MIRT1258635	hsa-miR-222	CLIP-seq
MIRT2302818	hsa-miR-224	CLIP-seq
MIRT1258601	hsa-miR-23a	CLIP-seq
MIRT1258602	hsa-miR-23b	CLIP-seq
MIRT1258603	hsa-miR-23c	CLIP-seq
MIRT2599541	hsa-miR-24	CLIP-seq
MIRT2599542	hsa-miR-2467-5p	CLIP-seq
MIRT2599543	hsa-miR-26a	CLIP-seq
MIRT2599544	hsa-miR-26b	CLIP-seq
MIRT2302819	hsa-miR-27a	CLIP-seq
MIRT2302820	hsa-miR-27b	CLIP-seq
MIRT2076227	hsa-miR-28-5p	CLIP-seq
MIRT2599545	hsa-miR-3119	CLIP-seq
MIRT2599546	hsa-miR-3121-5p	CLIP-seq
MIRT2599547	hsa-miR-3126-5p	CLIP-seq
MIRT2076228	hsa-miR-3139	CLIP-seq
MIRT2599548	hsa-miR-3148	CLIP-seq
MIRT2599549	hsa-miR-3160-5p	CLIP-seq
MIRT1258647	hsa-miR-3173-3p	CLIP-seq
MIRT2599550	hsa-miR-320a	CLIP-seq
MIRT2599551	hsa-miR-320b	CLIP-seq
MIRT2599552	hsa-miR-320c	CLIP-seq
MIRT2599553	hsa-miR-320d	CLIP-seq
MIRT1258651	hsa-miR-335	CLIP-seq
MIRT2599554	hsa-miR-3613-3p	CLIP-seq
MIRT1258656	hsa-miR-3617	CLIP-seq
MIRT2599555	hsa-miR-380	CLIP-seq
MIRT2599556	hsa-miR-3941	CLIP-seq
MIRT2599557	hsa-miR-3944-5p	CLIP-seq
MIRT2599558	hsa-miR-410	CLIP-seq
MIRT2599559	hsa-miR-4261	CLIP-seq
MIRT2599560	hsa-miR-4419a	CLIP-seq
MIRT2599561	hsa-miR-4428	CLIP-seq
MIRT2599562	hsa-miR-4429	CLIP-seq
MIRT2302823	hsa-miR-4438	CLIP-seq
MIRT2599563	hsa-miR-4465	CLIP-seq
MIRT2076230	hsa-miR-4483	CLIP-seq
MIRT2076231	hsa-miR-4487	CLIP-seq
MIRT2599564	hsa-miR-4495	CLIP-seq
MIRT2599565	hsa-miR-4496	CLIP-seq
MIRT2599566	hsa-miR-450b-5p	CLIP-seq
MIRT2599567	hsa-miR-4510	CLIP-seq
MIRT1258685	hsa-miR-4511	CLIP-seq
MIRT1258686	hsa-miR-451b	CLIP-seq
MIRT2302825	hsa-miR-4528	CLIP-seq
MIRT2599568	hsa-miR-466	CLIP-seq
MIRT1258689	hsa-miR-4662a-5p	CLIP-seq
MIRT2599569	hsa-miR-4668-5p	CLIP-seq
MIRT2599570	hsa-miR-4672	CLIP-seq
MIRT2599571	hsa-miR-4731-3p	CLIP-seq
MIRT2599572	hsa-miR-4735-5p	CLIP-seq
MIRT2076232	hsa-miR-4793-5p	CLIP-seq
MIRT2599573	hsa-miR-4801	CLIP-seq
MIRT2076222	hsa-miR-490-3p	CLIP-seq
MIRT1258701	hsa-miR-495	CLIP-seq
MIRT1258704	hsa-miR-499-5p	CLIP-seq
MIRT2302828	hsa-miR-5095	CLIP-seq
MIRT2302829	hsa-miR-513a-5p	CLIP-seq
MIRT1258707	hsa-miR-513c	CLIP-seq
MIRT1258708	hsa-miR-514b-5p	CLIP-seq
MIRT2599574	hsa-miR-518a-5p	CLIP-seq
MIRT2599575	hsa-miR-527	CLIP-seq
MIRT1258718	hsa-miR-545	CLIP-seq
MIRT2599576	hsa-miR-548ac	CLIP-seq
MIRT2599577	hsa-miR-548ae	CLIP-seq
MIRT2599578	hsa-miR-548aj	CLIP-seq
MIRT2599579	hsa-miR-548am	CLIP-seq
MIRT2302830	hsa-miR-548c-3p	CLIP-seq
MIRT2599580	hsa-miR-548d-3p	CLIP-seq
MIRT1258722	hsa-miR-548n	CLIP-seq
MIRT2302831	hsa-miR-548t	CLIP-seq
MIRT2599581	hsa-miR-548x	CLIP-seq
MIRT2599582	hsa-miR-548z	CLIP-seq
MIRT2599583	hsa-miR-583	CLIP-seq
MIRT2599584	hsa-miR-595	CLIP-seq
MIRT2076233	hsa-miR-708	CLIP-seq
MIRT2599585	hsa-miR-765	CLIP-seq
MIRT2076234	hsa-miR-876-3p	CLIP-seq
MIRT1258605	hsa-miR-103a	CLIP-seq
MIRT2599539	hsa-miR-105	CLIP-seq
MIRT2076225	hsa-miR-1293	CLIP-seq
MIRT2599540	hsa-miR-1297	CLIP-seq
MIRT1258627	hsa-miR-208a	CLIP-seq
MIRT1258628	hsa-miR-208b	CLIP-seq
MIRT1258634	hsa-miR-221	CLIP-seq
MIRT1258635	hsa-miR-222	CLIP-seq
MIRT2302818	hsa-miR-224	CLIP-seq
MIRT1258601	hsa-miR-23a	CLIP-seq
MIRT1258602	hsa-miR-23b	CLIP-seq
MIRT1258603	hsa-miR-23c	CLIP-seq
MIRT2599541	hsa-miR-24	CLIP-seq
MIRT2599542	hsa-miR-2467-5p	CLIP-seq
MIRT2599543	hsa-miR-26a	CLIP-seq
MIRT2599544	hsa-miR-26b	CLIP-seq
MIRT2076227	hsa-miR-28-5p	CLIP-seq
MIRT2599545	hsa-miR-3119	CLIP-seq
MIRT2599546	hsa-miR-3121-5p	CLIP-seq
MIRT2076228	hsa-miR-3139	CLIP-seq
MIRT1258647	hsa-miR-3173-3p	CLIP-seq
MIRT2599550	hsa-miR-320a	CLIP-seq
MIRT2599551	hsa-miR-320b	CLIP-seq
MIRT2599552	hsa-miR-320c	CLIP-seq
MIRT2599553	hsa-miR-320d	CLIP-seq
MIRT1258651	hsa-miR-335	CLIP-seq
MIRT2599554	hsa-miR-3613-3p	CLIP-seq
MIRT1258656	hsa-miR-3617	CLIP-seq
MIRT2599555	hsa-miR-380	CLIP-seq
MIRT2599556	hsa-miR-3941	CLIP-seq
MIRT2599557	hsa-miR-3944-5p	CLIP-seq
MIRT2599558	hsa-miR-410	CLIP-seq
MIRT2599559	hsa-miR-4261	CLIP-seq
MIRT2599561	hsa-miR-4428	CLIP-seq
MIRT2599562	hsa-miR-4429	CLIP-seq
MIRT2599563	hsa-miR-4465	CLIP-seq
MIRT2076230	hsa-miR-4483	CLIP-seq
MIRT2076231	hsa-miR-4487	CLIP-seq
MIRT2599564	hsa-miR-4495	CLIP-seq
MIRT2599565	hsa-miR-4496	CLIP-seq
MIRT2599566	hsa-miR-450b-5p	CLIP-seq
MIRT1258685	hsa-miR-4511	CLIP-seq
MIRT1258686	hsa-miR-451b	CLIP-seq
MIRT2302825	hsa-miR-4528	CLIP-seq
MIRT2599568	hsa-miR-466	CLIP-seq
MIRT1258689	hsa-miR-4662a-5p	CLIP-seq
MIRT2599570	hsa-miR-4672	CLIP-seq
MIRT2599571	hsa-miR-4731-3p	CLIP-seq
MIRT2076232	hsa-miR-4793-5p	CLIP-seq
MIRT2599573	hsa-miR-4801	CLIP-seq
MIRT1258701	hsa-miR-495	CLIP-seq
MIRT1258704	hsa-miR-499-5p	CLIP-seq
MIRT2599574	hsa-miR-518a-5p	CLIP-seq
MIRT2599575	hsa-miR-527	CLIP-seq
MIRT1258718	hsa-miR-545	CLIP-seq
MIRT2599576	hsa-miR-548ac	CLIP-seq
MIRT2599577	hsa-miR-548ae	CLIP-seq
MIRT2599578	hsa-miR-548aj	CLIP-seq
MIRT2599579	hsa-miR-548am	CLIP-seq
MIRT2302830	hsa-miR-548c-3p	CLIP-seq
MIRT2599580	hsa-miR-548d-3p	CLIP-seq
MIRT1258722	hsa-miR-548n	CLIP-seq
MIRT2302831	hsa-miR-548t	CLIP-seq
MIRT2599581	hsa-miR-548x	CLIP-seq
MIRT2599582	hsa-miR-548z	CLIP-seq
MIRT2599583	hsa-miR-583	CLIP-seq
MIRT2599584	hsa-miR-595	CLIP-seq
MIRT2076233	hsa-miR-708	CLIP-seq
MIRT2599585	hsa-miR-765	CLIP-seq
MIRT2076234	hsa-miR-876-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000082	Process	G1/S transition of mitotic cell cycle	IBA
GO:0000082	Process	G1/S transition of mitotic cell cycle	TAS	9013334
GO:0002376	Process	Immune system process	IEA
GO:0004721	Function	Phosphoprotein phosphatase activity	IEA
GO:0004722	Function	Protein serine/threonine phosphatase activity	IBA
GO:0004722	Function	Protein serine/threonine phosphatase activity	IDA	32474700
GO:0004722	Function	Protein serine/threonine phosphatase activity	IEA
GO:0004722	Function	Protein serine/threonine phosphatase activity	TAS	9013334
GO:0005515	Function	Protein binding	IPI	9647778, 16085932, 16769727, 17079228, 17384681, 18186651, 21187329, 24255178, 26496610, 28330616, 32296183, 33961781, 35271311, 35512704
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006470	Process	Protein dephosphorylation	IDA
GO:0006470	Process	Protein dephosphorylation	TAS	9013334
GO:0016787	Function	Hydrolase activity	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048208	Process	COPII vesicle coating	TAS
GO:0140896	Process	CGAS/STING signaling pathway	IDA	30842659, 30842662, 32911482, 32912999
GO:0160049	Process	Negative regulation of cGAS/STING signaling pathway	IDA	32474700

Other IDs

• MIM: 612725
• HGNC: 9323
• e!Ensembl: ENSG00000119414

Protein

• UniProt ID: O00743
• Protein name: Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) [Cleaved into: Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed]
• Protein function: Catalytic subunit of protein phosphatase 6 (PP6) (PubMed:17079228, PubMed:29053956, PubMed:32474700). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation (PubMed:10227379). N-termin
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00149	Metallophos	46 → 241	Calcineurin-like phosphoesterase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen. {ECO:0000269|PubMed:16769727, ECO:0000269|Pu
• Sequence:

  MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD
  LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT
  QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE
  RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV
  HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT
  TPYFL

• Sequence length: 305

Pathways

Reactome:

COPII-mediated vesicle transport

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CANNABIS DEPENDENCE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, BASAL CELL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MELANOMA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Diseases	Breast disease	Pubtator	21451261	Inhibit	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	21451261	Inhibit	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	Pubtator	24718460	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	21481188	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Basal Cell	Carcinoma	CTD_human_DG	26950094		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Celiac Disease	Celiac disease	BEFREE	19626039		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	35027503	Associate	★☆☆☆☆ Found in Text Mining only
Cutaneous Melanoma	Melanoma	CLINVAR_DG	26619011		★☆☆☆☆ Found in Text Mining only
Cutaneous Melanoma	Melanoma	CGI_DG			★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	22158480		★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	30929511		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	21481188		★☆☆☆☆ Found in Text Mining only
Malignant mesothelioma	Malignant Mesothelioma	BEFREE	20463022		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of thyroid	Thyroid cancer	BEFREE	24718460		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	22842228		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	22817889, 22842228, 24336958, 25759478, 36071040	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
melanoma	Melanoma	BEFREE	22842228, 23729733, 24336958, 25759478		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
melanoma	Melanoma	CTD_human_DG	22842228		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
melanoma	Melanoma	CGI_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mesothelioma Malignant	Mesothelioma	Pubtator	20463022	Associate	★☆☆☆☆ Found in Text Mining only
Metastatic melanoma	Metastatic Melanoma	BEFREE	24336958		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	33270085	Associate	★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	BEFREE	26138368		★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	31427592	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of lung	Lung carcinoma	CLINVAR_DG	26619011		★☆☆☆☆ Found in Text Mining only
Thyroid carcinoma	Thyroid Carcinoma	BEFREE	24718460		★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasm	Thyroid Neoplasm	BEFREE	24718460		★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	24718460	Associate	★☆☆☆☆ Found in Text Mining only