Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	55272
Gene name	IMP U3 small nucleolar ribonucleoprotein 3
Gene symbol	IMP3
Synonyms (NCBI Gene)	BRMS2C15orf12MRPS4
Chromosome	15
Chromosome location	15q24.2
Summary	This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008]

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Show/Hide all (328)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025305	hsa-miR-34a-5p	Proteomics	21566225
MIRT028891	hsa-miR-26b-5p	Microarray	19088304
MIRT450122	hsa-miR-548ac	PAR-CLIP	22100165
MIRT450120	hsa-miR-548bb-3p	PAR-CLIP	22100165
MIRT450121	hsa-miR-548d-3p	PAR-CLIP	22100165
MIRT450119	hsa-miR-548h-3p	PAR-CLIP	22100165
MIRT450118	hsa-miR-548z	PAR-CLIP	22100165
MIRT450117	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT450116	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT450115	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT450114	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT450113	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT450112	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT450111	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT450110	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT450108	hsa-miR-3163	PAR-CLIP	22100165
MIRT450109	hsa-miR-4328	PAR-CLIP	22100165
MIRT450107	hsa-miR-5008-5p	PAR-CLIP	22100165
MIRT450106	hsa-miR-6089	PAR-CLIP	22100165
MIRT450105	hsa-miR-340-5p	PAR-CLIP	22100165
MIRT450104	hsa-miR-6765-5p	PAR-CLIP	22100165
MIRT450103	hsa-miR-1304-5p	PAR-CLIP	22100165
MIRT450122	hsa-miR-548ac	PAR-CLIP	22100165
MIRT450120	hsa-miR-548bb-3p	PAR-CLIP	22100165
MIRT450121	hsa-miR-548d-3p	PAR-CLIP	22100165
MIRT450119	hsa-miR-548h-3p	PAR-CLIP	22100165
MIRT450118	hsa-miR-548z	PAR-CLIP	22100165
MIRT450117	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT450116	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT450115	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT450114	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT450113	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT450112	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT450111	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT450110	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT450108	hsa-miR-3163	PAR-CLIP	22100165
MIRT450109	hsa-miR-4328	PAR-CLIP	22100165
MIRT450107	hsa-miR-5008-5p	PAR-CLIP	22100165
MIRT450106	hsa-miR-6089	PAR-CLIP	22100165
MIRT450105	hsa-miR-340-5p	PAR-CLIP	22100165
MIRT450104	hsa-miR-6765-5p	PAR-CLIP	22100165
MIRT450103	hsa-miR-1304-5p	PAR-CLIP	22100165
MIRT1065645	hsa-miR-1208	CLIP-seq
MIRT1065646	hsa-miR-1224-5p	CLIP-seq
MIRT1065647	hsa-miR-124	CLIP-seq
MIRT1065648	hsa-miR-1260	CLIP-seq
MIRT1065649	hsa-miR-1260b	CLIP-seq
MIRT1065650	hsa-miR-1304	CLIP-seq
MIRT1065651	hsa-miR-1321	CLIP-seq
MIRT1065652	hsa-miR-136	CLIP-seq
MIRT1065653	hsa-miR-145	CLIP-seq
MIRT1065654	hsa-miR-188-3p	CLIP-seq
MIRT1065655	hsa-miR-1972	CLIP-seq
MIRT1065656	hsa-miR-199a-3p	CLIP-seq
MIRT1065657	hsa-miR-199b-3p	CLIP-seq
MIRT1065658	hsa-miR-3129-5p	CLIP-seq
MIRT1065659	hsa-miR-3140-5p	CLIP-seq
MIRT1065660	hsa-miR-3150b-3p	CLIP-seq
MIRT1065661	hsa-miR-3156-3p	CLIP-seq
MIRT1065662	hsa-miR-3180-5p	CLIP-seq
MIRT1065663	hsa-miR-323-3p	CLIP-seq
MIRT1065664	hsa-miR-330-3p	CLIP-seq
MIRT1065665	hsa-miR-338-3p	CLIP-seq
MIRT1065666	hsa-miR-340	CLIP-seq
MIRT1065667	hsa-miR-3663-3p	CLIP-seq
MIRT1065668	hsa-miR-3682-5p	CLIP-seq
MIRT1065669	hsa-miR-3691-3p	CLIP-seq
MIRT1065670	hsa-miR-376a	CLIP-seq
MIRT1065671	hsa-miR-376b	CLIP-seq
MIRT1065672	hsa-miR-3915	CLIP-seq
MIRT1065673	hsa-miR-3925-3p	CLIP-seq
MIRT1065674	hsa-miR-4259	CLIP-seq
MIRT1065675	hsa-miR-4260	CLIP-seq
MIRT1065676	hsa-miR-4275	CLIP-seq
MIRT1065677	hsa-miR-4301	CLIP-seq
MIRT1065678	hsa-miR-4325	CLIP-seq
MIRT1065679	hsa-miR-4424	CLIP-seq
MIRT1065680	hsa-miR-4444	CLIP-seq
MIRT1065681	hsa-miR-4446-5p	CLIP-seq
MIRT1065682	hsa-miR-4474-5p	CLIP-seq
MIRT1065683	hsa-miR-451b	CLIP-seq
MIRT1065684	hsa-miR-452	CLIP-seq
MIRT1065685	hsa-miR-4530	CLIP-seq
MIRT1065686	hsa-miR-455-3p	CLIP-seq
MIRT1065687	hsa-miR-4650-5p	CLIP-seq
MIRT1065688	hsa-miR-4672	CLIP-seq
MIRT1065689	hsa-miR-4676-3p	CLIP-seq
MIRT1065690	hsa-miR-4683	CLIP-seq
MIRT1065691	hsa-miR-4689	CLIP-seq
MIRT1065692	hsa-miR-4704-5p	CLIP-seq
MIRT1065693	hsa-miR-4711-5p	CLIP-seq
MIRT1065694	hsa-miR-4729	CLIP-seq
MIRT1065695	hsa-miR-4739	CLIP-seq
MIRT1065696	hsa-miR-4756-5p	CLIP-seq
MIRT1065697	hsa-miR-4780	CLIP-seq
MIRT1065698	hsa-miR-4784	CLIP-seq
MIRT1065699	hsa-miR-4796-3p	CLIP-seq
MIRT1065700	hsa-miR-4804-3p	CLIP-seq
MIRT1065701	hsa-miR-486-3p	CLIP-seq
MIRT1065702	hsa-miR-506	CLIP-seq
MIRT1065703	hsa-miR-518a-5p	CLIP-seq
MIRT1065704	hsa-miR-520d-5p	CLIP-seq
MIRT1065705	hsa-miR-520g	CLIP-seq
MIRT1065706	hsa-miR-520h	CLIP-seq
MIRT1065707	hsa-miR-524-5p	CLIP-seq
MIRT1065708	hsa-miR-527	CLIP-seq
MIRT1065709	hsa-miR-548ae	CLIP-seq
MIRT1065710	hsa-miR-548aj	CLIP-seq
MIRT1065711	hsa-miR-548am	CLIP-seq
MIRT1065712	hsa-miR-548x	CLIP-seq
MIRT1065713	hsa-miR-665	CLIP-seq
MIRT1065714	hsa-miR-720	CLIP-seq
MIRT1065715	hsa-miR-765	CLIP-seq
MIRT1065716	hsa-miR-766	CLIP-seq
MIRT1065717	hsa-miR-936	CLIP-seq
MIRT1065646	hsa-miR-1224-5p	CLIP-seq
MIRT2015608	hsa-miR-1268	CLIP-seq
MIRT2015609	hsa-miR-1268b	CLIP-seq
MIRT1065650	hsa-miR-1304	CLIP-seq
MIRT1065651	hsa-miR-1321	CLIP-seq
MIRT1065652	hsa-miR-136	CLIP-seq
MIRT1065653	hsa-miR-145	CLIP-seq
MIRT1065659	hsa-miR-3140-5p	CLIP-seq
MIRT1065660	hsa-miR-3150b-3p	CLIP-seq
MIRT2015610	hsa-miR-3167	CLIP-seq
MIRT1065662	hsa-miR-3180-5p	CLIP-seq
MIRT1065663	hsa-miR-323-3p	CLIP-seq
MIRT1065664	hsa-miR-330-3p	CLIP-seq
MIRT2015611	hsa-miR-3607-3p	CLIP-seq
MIRT1065667	hsa-miR-3663-3p	CLIP-seq
MIRT2015612	hsa-miR-3686	CLIP-seq
MIRT1065670	hsa-miR-376a	CLIP-seq
MIRT1065671	hsa-miR-376b	CLIP-seq
MIRT1065672	hsa-miR-3915	CLIP-seq
MIRT2015613	hsa-miR-3926	CLIP-seq
MIRT1065674	hsa-miR-4259	CLIP-seq
MIRT1065675	hsa-miR-4260	CLIP-seq
MIRT2015614	hsa-miR-4261	CLIP-seq
MIRT1065678	hsa-miR-4325	CLIP-seq
MIRT1065679	hsa-miR-4424	CLIP-seq
MIRT1065680	hsa-miR-4444	CLIP-seq
MIRT1065681	hsa-miR-4446-5p	CLIP-seq
MIRT2015615	hsa-miR-4450	CLIP-seq
MIRT1065682	hsa-miR-4474-5p	CLIP-seq
MIRT1065683	hsa-miR-451b	CLIP-seq
MIRT1065686	hsa-miR-455-3p	CLIP-seq
MIRT1065688	hsa-miR-4672	CLIP-seq
MIRT1065690	hsa-miR-4683	CLIP-seq
MIRT1065691	hsa-miR-4689	CLIP-seq
MIRT1065692	hsa-miR-4704-5p	CLIP-seq
MIRT1065694	hsa-miR-4729	CLIP-seq
MIRT1065695	hsa-miR-4739	CLIP-seq
MIRT1065696	hsa-miR-4756-5p	CLIP-seq
MIRT1065697	hsa-miR-4780	CLIP-seq
MIRT1065698	hsa-miR-4784	CLIP-seq
MIRT1065700	hsa-miR-4804-3p	CLIP-seq
MIRT1065701	hsa-miR-486-3p	CLIP-seq
MIRT2015616	hsa-miR-489	CLIP-seq
MIRT2015617	hsa-miR-491-5p	CLIP-seq
MIRT1065704	hsa-miR-520d-5p	CLIP-seq
MIRT1065707	hsa-miR-524-5p	CLIP-seq
MIRT1065709	hsa-miR-548ae	CLIP-seq
MIRT1065710	hsa-miR-548aj	CLIP-seq
MIRT1065711	hsa-miR-548am	CLIP-seq
MIRT1065712	hsa-miR-548x	CLIP-seq
MIRT2015618	hsa-miR-561	CLIP-seq
MIRT1065713	hsa-miR-665	CLIP-seq
MIRT1065714	hsa-miR-720	CLIP-seq
MIRT1065715	hsa-miR-765	CLIP-seq
MIRT2015619	hsa-miR-876-5p	CLIP-seq
MIRT1065645	hsa-miR-1208	CLIP-seq
MIRT1065646	hsa-miR-1224-5p	CLIP-seq
MIRT1065647	hsa-miR-124	CLIP-seq
MIRT1065648	hsa-miR-1260	CLIP-seq
MIRT1065649	hsa-miR-1260b	CLIP-seq
MIRT2015608	hsa-miR-1268	CLIP-seq
MIRT2015609	hsa-miR-1268b	CLIP-seq
MIRT1065650	hsa-miR-1304	CLIP-seq
MIRT1065651	hsa-miR-1321	CLIP-seq
MIRT1065652	hsa-miR-136	CLIP-seq
MIRT1065653	hsa-miR-145	CLIP-seq
MIRT2247958	hsa-miR-1825	CLIP-seq
MIRT1065654	hsa-miR-188-3p	CLIP-seq
MIRT1065655	hsa-miR-1972	CLIP-seq
MIRT1065656	hsa-miR-199a-3p	CLIP-seq
MIRT1065657	hsa-miR-199b-3p	CLIP-seq
MIRT1065658	hsa-miR-3129-5p	CLIP-seq
MIRT2247959	hsa-miR-3130-3p	CLIP-seq
MIRT1065659	hsa-miR-3140-5p	CLIP-seq
MIRT1065660	hsa-miR-3150b-3p	CLIP-seq
MIRT1065661	hsa-miR-3156-3p	CLIP-seq
MIRT2015610	hsa-miR-3167	CLIP-seq
MIRT2247960	hsa-miR-3168	CLIP-seq
MIRT1065662	hsa-miR-3180-5p	CLIP-seq
MIRT1065663	hsa-miR-323-3p	CLIP-seq
MIRT1065664	hsa-miR-330-3p	CLIP-seq
MIRT1065666	hsa-miR-340	CLIP-seq
MIRT1065667	hsa-miR-3663-3p	CLIP-seq
MIRT1065668	hsa-miR-3682-5p	CLIP-seq
MIRT1065669	hsa-miR-3691-3p	CLIP-seq
MIRT1065670	hsa-miR-376a	CLIP-seq
MIRT1065671	hsa-miR-376b	CLIP-seq
MIRT1065672	hsa-miR-3915	CLIP-seq
MIRT2015613	hsa-miR-3926	CLIP-seq
MIRT2247961	hsa-miR-3938	CLIP-seq
MIRT2247962	hsa-miR-4252	CLIP-seq
MIRT1065674	hsa-miR-4259	CLIP-seq
MIRT1065675	hsa-miR-4260	CLIP-seq
MIRT2015614	hsa-miR-4261	CLIP-seq
MIRT2247963	hsa-miR-4263	CLIP-seq
MIRT1065676	hsa-miR-4275	CLIP-seq
MIRT2247964	hsa-miR-4292	CLIP-seq
MIRT1065677	hsa-miR-4301	CLIP-seq
MIRT2247965	hsa-miR-4308	CLIP-seq
MIRT1065678	hsa-miR-4325	CLIP-seq
MIRT1065679	hsa-miR-4424	CLIP-seq
MIRT1065680	hsa-miR-4444	CLIP-seq
MIRT1065681	hsa-miR-4446-5p	CLIP-seq
MIRT2015615	hsa-miR-4450	CLIP-seq
MIRT1065682	hsa-miR-4474-5p	CLIP-seq
MIRT2247966	hsa-miR-4502	CLIP-seq
MIRT2247967	hsa-miR-4511	CLIP-seq
MIRT1065683	hsa-miR-451b	CLIP-seq
MIRT1065684	hsa-miR-452	CLIP-seq
MIRT1065686	hsa-miR-455-3p	CLIP-seq
MIRT1065687	hsa-miR-4650-5p	CLIP-seq
MIRT1065688	hsa-miR-4672	CLIP-seq
MIRT1065689	hsa-miR-4676-3p	CLIP-seq
MIRT1065690	hsa-miR-4683	CLIP-seq
MIRT1065691	hsa-miR-4689	CLIP-seq
MIRT1065692	hsa-miR-4704-5p	CLIP-seq
MIRT1065693	hsa-miR-4711-5p	CLIP-seq
MIRT2247968	hsa-miR-4722-3p	CLIP-seq
MIRT1065694	hsa-miR-4729	CLIP-seq
MIRT2247969	hsa-miR-4731-3p	CLIP-seq
MIRT1065695	hsa-miR-4739	CLIP-seq
MIRT1065696	hsa-miR-4756-5p	CLIP-seq
MIRT2247970	hsa-miR-4763-5p	CLIP-seq
MIRT1065697	hsa-miR-4780	CLIP-seq
MIRT1065698	hsa-miR-4784	CLIP-seq
MIRT2247971	hsa-miR-4786-3p	CLIP-seq
MIRT2247972	hsa-miR-4801	CLIP-seq
MIRT1065700	hsa-miR-4804-3p	CLIP-seq
MIRT1065701	hsa-miR-486-3p	CLIP-seq
MIRT2015616	hsa-miR-489	CLIP-seq
MIRT2015617	hsa-miR-491-5p	CLIP-seq
MIRT1065702	hsa-miR-506	CLIP-seq
MIRT2247973	hsa-miR-512-3p	CLIP-seq
MIRT1065704	hsa-miR-520d-5p	CLIP-seq
MIRT1065707	hsa-miR-524-5p	CLIP-seq
MIRT2247974	hsa-miR-543	CLIP-seq
MIRT1065709	hsa-miR-548ae	CLIP-seq
MIRT1065710	hsa-miR-548aj	CLIP-seq
MIRT1065711	hsa-miR-548am	CLIP-seq
MIRT2247975	hsa-miR-548b-3p	CLIP-seq
MIRT1065712	hsa-miR-548x	CLIP-seq
MIRT2015618	hsa-miR-561	CLIP-seq
MIRT2247976	hsa-miR-586	CLIP-seq
MIRT1065713	hsa-miR-665	CLIP-seq
MIRT2247977	hsa-miR-670	CLIP-seq
MIRT1065714	hsa-miR-720	CLIP-seq
MIRT2247978	hsa-miR-760	CLIP-seq
MIRT1065715	hsa-miR-765	CLIP-seq
MIRT2247979	hsa-miR-767-5p	CLIP-seq
MIRT2015619	hsa-miR-876-5p	CLIP-seq
MIRT1065717	hsa-miR-936	CLIP-seq
MIRT1065645	hsa-miR-1208	CLIP-seq
MIRT1065647	hsa-miR-124	CLIP-seq
MIRT1065676	hsa-miR-4275	CLIP-seq
MIRT1065683	hsa-miR-451b	CLIP-seq
MIRT1065684	hsa-miR-452	CLIP-seq
MIRT1065688	hsa-miR-4672	CLIP-seq
MIRT1065689	hsa-miR-4676-3p	CLIP-seq
MIRT1065700	hsa-miR-4804-3p	CLIP-seq
MIRT1065702	hsa-miR-506	CLIP-seq
MIRT1065713	hsa-miR-665	CLIP-seq
MIRT1065646	hsa-miR-1224-5p	CLIP-seq
MIRT1065655	hsa-miR-1972	CLIP-seq
MIRT1065660	hsa-miR-3150b-3p	CLIP-seq
MIRT1065665	hsa-miR-338-3p	CLIP-seq
MIRT2015611	hsa-miR-3607-3p	CLIP-seq
MIRT2551708	hsa-miR-3653	CLIP-seq
MIRT2551709	hsa-miR-3658	CLIP-seq
MIRT1065667	hsa-miR-3663-3p	CLIP-seq
MIRT2015612	hsa-miR-3686	CLIP-seq
MIRT1065670	hsa-miR-376a	CLIP-seq
MIRT1065671	hsa-miR-376b	CLIP-seq
MIRT1065672	hsa-miR-3915	CLIP-seq
MIRT1065673	hsa-miR-3925-3p	CLIP-seq
MIRT2247962	hsa-miR-4252	CLIP-seq
MIRT1065681	hsa-miR-4446-5p	CLIP-seq
MIRT2247966	hsa-miR-4502	CLIP-seq
MIRT2247967	hsa-miR-4511	CLIP-seq
MIRT1065685	hsa-miR-4530	CLIP-seq
MIRT1065687	hsa-miR-4650-5p	CLIP-seq
MIRT1065691	hsa-miR-4689	CLIP-seq
MIRT1065693	hsa-miR-4711-5p	CLIP-seq
MIRT2247968	hsa-miR-4722-3p	CLIP-seq
MIRT2247970	hsa-miR-4763-5p	CLIP-seq
MIRT1065697	hsa-miR-4780	CLIP-seq
MIRT1065698	hsa-miR-4784	CLIP-seq
MIRT2247975	hsa-miR-548b-3p	CLIP-seq
MIRT1065716	hsa-miR-766	CLIP-seq
MIRT1065646	hsa-miR-1224-5p	CLIP-seq
MIRT1065655	hsa-miR-1972	CLIP-seq
MIRT1065660	hsa-miR-3150b-3p	CLIP-seq
MIRT1065665	hsa-miR-338-3p	CLIP-seq
MIRT2015611	hsa-miR-3607-3p	CLIP-seq
MIRT2551708	hsa-miR-3653	CLIP-seq
MIRT2551709	hsa-miR-3658	CLIP-seq
MIRT1065667	hsa-miR-3663-3p	CLIP-seq
MIRT2015612	hsa-miR-3686	CLIP-seq
MIRT1065670	hsa-miR-376a	CLIP-seq
MIRT1065671	hsa-miR-376b	CLIP-seq
MIRT1065672	hsa-miR-3915	CLIP-seq
MIRT1065673	hsa-miR-3925-3p	CLIP-seq
MIRT2247962	hsa-miR-4252	CLIP-seq
MIRT1065681	hsa-miR-4446-5p	CLIP-seq
MIRT2247966	hsa-miR-4502	CLIP-seq
MIRT2247967	hsa-miR-4511	CLIP-seq
MIRT1065685	hsa-miR-4530	CLIP-seq
MIRT1065687	hsa-miR-4650-5p	CLIP-seq
MIRT1065691	hsa-miR-4689	CLIP-seq
MIRT1065693	hsa-miR-4711-5p	CLIP-seq
MIRT1065697	hsa-miR-4780	CLIP-seq
MIRT1065698	hsa-miR-4784	CLIP-seq
MIRT2247975	hsa-miR-548b-3p	CLIP-seq
MIRT1065716	hsa-miR-766	CLIP-seq

Show/Hide all (27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	12655004, 19060904, 25416956, 29892012, 31515488, 32296183, 33961781, 35271311
GO:0005634	Component	Nucleus	IDA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA	12655004
GO:0005730	Component	Nucleolus	IEA
GO:0005730	Component	Nucleolus	NAS	12655004
GO:0005829	Component	Cytosol	IDA
GO:0006364	Process	RRNA processing	IBA
GO:0006364	Process	RRNA processing	IEA
GO:0006364	Process	RRNA processing	IEA
GO:0019843	Function	RRNA binding	IEA
GO:0030490	Process	Maturation of SSU-rRNA	NAS	12655004
GO:0030515	Function	SnoRNA binding	IBA
GO:0030684	Component	Preribosome	IDA	12655004
GO:0032040	Component	Small-subunit processome	IBA
GO:0032040	Component	Small-subunit processome	IDA	34516797
GO:0034457	Component	Mpp10 complex	IBA
GO:0034457	Component	Mpp10 complex	IDA	12655004
GO:0034457	Component	Mpp10 complex	IPI	12655004
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0042274	Process	Ribosomal small subunit biogenesis	IBA
GO:0042274	Process	Ribosomal small subunit biogenesis	IDA	34516797
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
612980	14497	ENSG00000177971

Q9NV31

Protein name

U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) (BRMS2)

Protein function

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukary

PDB

2CQJ , 7MQ8 , 7MQ9 , 7MQA

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00163	Ribosomal_S4	4 → 123	Ribosomal protein S4/S9 N-terminal domain	Family
PF01479	S4	109 → 156	S4 domain	Domain

Sequence

MVRKLKFHEQKLLKQVDFLNWEVTDHNLHELRVLRRYRLQRREDYTRYNQLSRAVRELAR
RLRDLPERDQFRVRASAALLDKLYALGLVPTRGSLELCDFVTASSFCRRRLPTVLLKLRM
AQHLQAAVAFVEQGHVRVGPDVVTDPAFLVTRSMEDFVTWVDSSKIKRHVLEYNEERDDF
DLEA

Sequence length

184

Interactions

View interactions

	KEGG		Reactome
	Ribosome biogenesis in eukaryotes		Major pathway of rRNA processing in the nucleolus and cytosol

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

IMP3 (IMP U3 small nucleolar ribonucleoprotein 3)