Gene Gene information from NCBI Gene database.
Entrez ID 55238
Gene name Solute carrier family 38 member 7
Gene symbol SLC38A7
Synonyms (NCBI Gene)
SNAT7
Chromosome 16
Chromosome location 16q21
miRNA miRNA information provided by mirtarbase database.
524
miRTarBase ID miRNA Experiments Reference
MIRT040340 hsa-miR-615-3p CLASH 23622248
MIRT682192 hsa-miR-6888-5p HITS-CLIP 23706177
MIRT682191 hsa-miR-3929 HITS-CLIP 23706177
MIRT682190 hsa-miR-4419b HITS-CLIP 23706177
MIRT682189 hsa-miR-4478 HITS-CLIP 23706177
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
26
GO ID Ontology Definition Evidence Reference
GO:0003333 Process Amino acid transmembrane transport IBA
GO:0005515 Function Protein binding IPI 25416956, 32296183, 35561222
GO:0005764 Component Lysosome IEA
GO:0005765 Component Lysosomal membrane IDA 35561222
GO:0005765 Component Lysosomal membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
614236 25582 ENSG00000103042
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NVC3
Protein name Sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7)
Protein function Symporter that selectively cotransports sodium ions and amino acids, such as L-glutamine and L-asparagine from the lysosome into the cytoplasm and may participates in mTORC1 activation (PubMed:28416685, PubMed:35561222). The transport activity r
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01490 Aa_trans 49 456 Transmembrane amino acid transporter protein Family
Sequence
Sequence length 462
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
AUTISM SPECTRUM DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
INSOMNIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OBESITY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Classical phenylketonuria Phenylketonuria BEFREE 11005872
★☆☆☆☆
Found in Text Mining only
Colorectal Carcinoma Colorectal Cancer BEFREE 31092450
★☆☆☆☆
Found in Text Mining only
Diabetes Mellitus Type 2 Diabetes mellitus, type 2 Pubtator 36364703, 40141237 Associate
★☆☆☆☆
Found in Text Mining only
Diabetic Angiopathies Diabetic angiopathies Pubtator 36364703 Associate
★☆☆☆☆
Found in Text Mining only
Diabetic Retinopathy Diabetic retinopathy Pubtator 36364703 Associate
★☆☆☆☆
Found in Text Mining only
Essential Tremor Tremor BEFREE 27624392
★☆☆☆☆
Found in Text Mining only
Major Depressive Disorder Mental Depression BEFREE 27723767
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of pancreas Pancreatic cancer BEFREE 27747870
★☆☆☆☆
Found in Text Mining only
Malignant Neoplasms Malignant Neoplasm BEFREE 29764521
★☆☆☆☆
Found in Text Mining only
melanoma Melanoma BEFREE 29487283
★☆☆☆☆
Found in Text Mining only