LRRC20 (leucine rich repeat containing 20)

Gene

• Entrez ID: 55222
• Gene name: Leucine rich repeat containing 20
• Gene symbol: LRRC20
• Synonyms (NCBI Gene): -
• Chromosome: 10
• Chromosome location: 10q22.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT030080	hsa-miR-26b-5p	Microarray	19088304
MIRT042109	hsa-miR-484	CLASH	23622248
MIRT722901	hsa-miR-6768-3p	HITS-CLIP	19536157
MIRT722900	hsa-miR-22-3p	HITS-CLIP	19536157
MIRT722899	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT722898	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT722897	hsa-miR-1913	HITS-CLIP	19536157
MIRT722896	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT722895	hsa-miR-4749-3p	HITS-CLIP	19536157
MIRT722894	hsa-miR-210-5p	HITS-CLIP	19536157
MIRT722893	hsa-miR-520a-5p	HITS-CLIP	19536157
MIRT722892	hsa-miR-525-5p	HITS-CLIP	19536157
MIRT722891	hsa-miR-3180-5p	HITS-CLIP	19536157
MIRT713943	hsa-miR-20a-3p	HITS-CLIP	19536157
MIRT713942	hsa-miR-4522	HITS-CLIP	19536157
MIRT474026	hsa-let-7g-5p	PAR-CLIP	23592263
MIRT474025	hsa-let-7f-5p	PAR-CLIP	23592263
MIRT474024	hsa-let-7d-5p	PAR-CLIP	23592263
MIRT474023	hsa-let-7c-5p	PAR-CLIP	23592263
MIRT474022	hsa-let-7e-5p	PAR-CLIP	23592263
MIRT474021	hsa-let-7i-5p	PAR-CLIP	23592263
MIRT474020	hsa-miR-4500	PAR-CLIP	23592263
MIRT474019	hsa-miR-4458	PAR-CLIP	23592263
MIRT474018	hsa-let-7a-5p	PAR-CLIP	23592263
MIRT474017	hsa-miR-98-5p	PAR-CLIP	23592263
MIRT474016	hsa-let-7b-5p	PAR-CLIP	23592263
MIRT474015	hsa-miR-5683	PAR-CLIP	23592263
MIRT474014	hsa-miR-3927-3p	PAR-CLIP	23592263
MIRT474012	hsa-miR-6831-5p	PAR-CLIP	23592263
MIRT474013	hsa-miR-1245b-3p	PAR-CLIP	23592263
MIRT474011	hsa-miR-140-3p	PAR-CLIP	23592263
MIRT474010	hsa-miR-544b	PAR-CLIP	23592263
MIRT474009	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT474008	hsa-miR-5004-5p	PAR-CLIP	23592263
MIRT474007	hsa-miR-4751	PAR-CLIP	23592263
MIRT474006	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT474005	hsa-miR-4784	PAR-CLIP	23592263
MIRT474004	hsa-miR-4434	PAR-CLIP	23592263
MIRT474003	hsa-miR-4516	PAR-CLIP	23592263
MIRT474002	hsa-miR-5703	PAR-CLIP	23592263
MIRT474001	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT474000	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT473999	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT473998	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT473997	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT473995	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT473996	hsa-miR-3935	PAR-CLIP	23592263
MIRT473994	hsa-miR-1233-5p	PAR-CLIP	23592263
MIRT473993	hsa-miR-6778-5p	PAR-CLIP	23592263
MIRT473992	hsa-miR-1224-5p	PAR-CLIP	23592263
MIRT473991	hsa-miR-4689	PAR-CLIP	23592263
MIRT473990	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT473989	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT473988	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT473987	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT473986	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT473985	hsa-miR-3689c	PAR-CLIP	23592263
MIRT473984	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT473983	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT473982	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT722901	hsa-miR-6768-3p	HITS-CLIP	19536157
MIRT722900	hsa-miR-22-3p	HITS-CLIP	19536157
MIRT722899	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT722898	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT722897	hsa-miR-1913	HITS-CLIP	19536157
MIRT722896	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT722895	hsa-miR-4749-3p	HITS-CLIP	19536157
MIRT722894	hsa-miR-210-5p	HITS-CLIP	19536157
MIRT722893	hsa-miR-520a-5p	HITS-CLIP	19536157
MIRT722892	hsa-miR-525-5p	HITS-CLIP	19536157
MIRT722891	hsa-miR-3180-5p	HITS-CLIP	19536157
MIRT713943	hsa-miR-20a-3p	HITS-CLIP	19536157
MIRT713942	hsa-miR-4522	HITS-CLIP	19536157
MIRT474026	hsa-let-7g-5p	PAR-CLIP	23592263
MIRT474025	hsa-let-7f-5p	PAR-CLIP	23592263
MIRT474024	hsa-let-7d-5p	PAR-CLIP	23592263
MIRT474023	hsa-let-7c-5p	PAR-CLIP	23592263
MIRT474022	hsa-let-7e-5p	PAR-CLIP	23592263
MIRT474021	hsa-let-7i-5p	PAR-CLIP	23592263
MIRT474020	hsa-miR-4500	PAR-CLIP	23592263
MIRT474019	hsa-miR-4458	PAR-CLIP	23592263
MIRT474018	hsa-let-7a-5p	PAR-CLIP	23592263
MIRT474017	hsa-miR-98-5p	PAR-CLIP	23592263
MIRT474016	hsa-let-7b-5p	PAR-CLIP	23592263
MIRT474015	hsa-miR-5683	PAR-CLIP	23592263
MIRT474014	hsa-miR-3927-3p	PAR-CLIP	23592263
MIRT474012	hsa-miR-6831-5p	PAR-CLIP	23592263
MIRT474013	hsa-miR-1245b-3p	PAR-CLIP	23592263
MIRT474011	hsa-miR-140-3p	PAR-CLIP	23592263
MIRT474010	hsa-miR-544b	PAR-CLIP	23592263
MIRT474009	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT474008	hsa-miR-5004-5p	PAR-CLIP	23592263
MIRT474007	hsa-miR-4751	PAR-CLIP	23592263
MIRT474006	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT474005	hsa-miR-4784	PAR-CLIP	23592263
MIRT474004	hsa-miR-4434	PAR-CLIP	23592263
MIRT474003	hsa-miR-4516	PAR-CLIP	23592263
MIRT474002	hsa-miR-5703	PAR-CLIP	23592263
MIRT474001	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT474000	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT473999	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT473998	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT473997	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT473995	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT473996	hsa-miR-3935	PAR-CLIP	23592263
MIRT473994	hsa-miR-1233-5p	PAR-CLIP	23592263
MIRT473993	hsa-miR-6778-5p	PAR-CLIP	23592263
MIRT473992	hsa-miR-1224-5p	PAR-CLIP	23592263
MIRT473991	hsa-miR-4689	PAR-CLIP	23592263
MIRT473990	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT473989	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT473988	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT473987	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT473986	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT473985	hsa-miR-3689c	PAR-CLIP	23592263
MIRT473984	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT473983	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT473982	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT1119048	hsa-miR-106a	CLIP-seq
MIRT1119049	hsa-miR-106b	CLIP-seq
MIRT1119050	hsa-miR-1205	CLIP-seq
MIRT1119051	hsa-miR-1234	CLIP-seq
MIRT1119052	hsa-miR-1245b-5p	CLIP-seq
MIRT1119053	hsa-miR-125a-3p	CLIP-seq
MIRT1119054	hsa-miR-1291	CLIP-seq
MIRT1119055	hsa-miR-17	CLIP-seq
MIRT1119056	hsa-miR-184	CLIP-seq
MIRT1119057	hsa-miR-20a	CLIP-seq
MIRT1119058	hsa-miR-20b	CLIP-seq
MIRT1119059	hsa-miR-219-1-3p	CLIP-seq
MIRT1119060	hsa-miR-296-5p	CLIP-seq
MIRT1119061	hsa-miR-3142	CLIP-seq
MIRT1119062	hsa-miR-3169	CLIP-seq
MIRT1119063	hsa-miR-3189-3p	CLIP-seq
MIRT1119064	hsa-miR-335	CLIP-seq
MIRT1119065	hsa-miR-3609	CLIP-seq
MIRT1119066	hsa-miR-3612	CLIP-seq
MIRT1119067	hsa-miR-3622a-5p	CLIP-seq
MIRT1119068	hsa-miR-3665	CLIP-seq
MIRT1119069	hsa-miR-3677-5p	CLIP-seq
MIRT1119070	hsa-miR-3689d	CLIP-seq
MIRT1119071	hsa-miR-3934	CLIP-seq
MIRT1119072	hsa-miR-432	CLIP-seq
MIRT1119073	hsa-miR-4443	CLIP-seq
MIRT1119074	hsa-miR-4463	CLIP-seq
MIRT1119075	hsa-miR-4468	CLIP-seq
MIRT1119076	hsa-miR-450b-3p	CLIP-seq
MIRT1119077	hsa-miR-4520b-3p	CLIP-seq
MIRT1119078	hsa-miR-4529-3p	CLIP-seq
MIRT1119079	hsa-miR-4650-5p	CLIP-seq
MIRT1119080	hsa-miR-4667-5p	CLIP-seq
MIRT1119081	hsa-miR-4682	CLIP-seq
MIRT1119082	hsa-miR-4700-3p	CLIP-seq
MIRT1119083	hsa-miR-4700-5p	CLIP-seq
MIRT1119084	hsa-miR-4701-5p	CLIP-seq
MIRT1119085	hsa-miR-4715-5p	CLIP-seq
MIRT1119086	hsa-miR-4740-5p	CLIP-seq
MIRT1119087	hsa-miR-4772-5p	CLIP-seq
MIRT1119088	hsa-miR-4796-3p	CLIP-seq
MIRT1119089	hsa-miR-4797-5p	CLIP-seq
MIRT1119090	hsa-miR-4804-5p	CLIP-seq
MIRT1119091	hsa-miR-486-3p	CLIP-seq
MIRT1119092	hsa-miR-516b	CLIP-seq
MIRT1119093	hsa-miR-519d	CLIP-seq
MIRT1119094	hsa-miR-548ah	CLIP-seq
MIRT1119095	hsa-miR-558	CLIP-seq
MIRT1119096	hsa-miR-571	CLIP-seq
MIRT1119097	hsa-miR-588	CLIP-seq
MIRT1119098	hsa-miR-615-5p	CLIP-seq
MIRT1119099	hsa-miR-637	CLIP-seq
MIRT1119100	hsa-miR-650	CLIP-seq
MIRT1119101	hsa-miR-657	CLIP-seq
MIRT1119102	hsa-miR-764	CLIP-seq
MIRT1119103	hsa-miR-769-3p	CLIP-seq
MIRT1119104	hsa-miR-890	CLIP-seq
MIRT1119105	hsa-miR-93	CLIP-seq
MIRT1119106	hsa-miR-1224-3p	CLIP-seq
MIRT1119107	hsa-miR-1914	CLIP-seq
MIRT1119059	hsa-miR-219-1-3p	CLIP-seq
MIRT1119070	hsa-miR-3689d	CLIP-seq
MIRT1119108	hsa-miR-370	CLIP-seq
MIRT1119109	hsa-miR-4470	CLIP-seq
MIRT1119110	hsa-miR-4684-3p	CLIP-seq
MIRT1119111	hsa-miR-4708-3p	CLIP-seq
MIRT1119112	hsa-miR-4763-5p	CLIP-seq
MIRT1119092	hsa-miR-516b	CLIP-seq
MIRT1119113	hsa-miR-550a	CLIP-seq
MIRT1119096	hsa-miR-571	CLIP-seq
MIRT1119106	hsa-miR-1224-3p	CLIP-seq
MIRT2033673	hsa-miR-1225-3p	CLIP-seq
MIRT2033674	hsa-miR-1225-5p	CLIP-seq
MIRT2033675	hsa-miR-1236	CLIP-seq
MIRT2033676	hsa-miR-1266	CLIP-seq
MIRT2033677	hsa-miR-1297	CLIP-seq
MIRT2033678	hsa-miR-1305	CLIP-seq
MIRT2033679	hsa-miR-138	CLIP-seq
MIRT1119056	hsa-miR-184	CLIP-seq
MIRT1119107	hsa-miR-1914	CLIP-seq
MIRT2033680	hsa-miR-1976	CLIP-seq
MIRT1119059	hsa-miR-219-1-3p	CLIP-seq
MIRT2033681	hsa-miR-24	CLIP-seq
MIRT2033682	hsa-miR-2467-3p	CLIP-seq
MIRT2033683	hsa-miR-26a	CLIP-seq
MIRT2033684	hsa-miR-26b	CLIP-seq
MIRT2033685	hsa-miR-3127-5p	CLIP-seq
MIRT2033686	hsa-miR-3144-5p	CLIP-seq
MIRT1119064	hsa-miR-335	CLIP-seq
MIRT2033687	hsa-miR-34b	CLIP-seq
MIRT2033688	hsa-miR-3664-3p	CLIP-seq
MIRT1119070	hsa-miR-3689d	CLIP-seq
MIRT1119108	hsa-miR-370	CLIP-seq
MIRT2033689	hsa-miR-3918	CLIP-seq
MIRT2033690	hsa-miR-3919	CLIP-seq
MIRT2033691	hsa-miR-4286	CLIP-seq
MIRT2033692	hsa-miR-4323	CLIP-seq
MIRT2033693	hsa-miR-4433	CLIP-seq
MIRT2033694	hsa-miR-4436b-3p	CLIP-seq
MIRT2033695	hsa-miR-4459	CLIP-seq
MIRT2033696	hsa-miR-4465	CLIP-seq
MIRT2033697	hsa-miR-4504	CLIP-seq
MIRT2033698	hsa-miR-4518	CLIP-seq
MIRT1119077	hsa-miR-4520b-3p	CLIP-seq
MIRT1119078	hsa-miR-4529-3p	CLIP-seq
MIRT1119110	hsa-miR-4684-3p	CLIP-seq
MIRT2033699	hsa-miR-4731-5p	CLIP-seq
MIRT2033700	hsa-miR-4753-3p	CLIP-seq
MIRT2033701	hsa-miR-4756-3p	CLIP-seq
MIRT1119112	hsa-miR-4763-5p	CLIP-seq
MIRT2033702	hsa-miR-4768-3p	CLIP-seq
MIRT1119090	hsa-miR-4804-5p	CLIP-seq
MIRT2033703	hsa-miR-498	CLIP-seq
MIRT2033704	hsa-miR-515-5p	CLIP-seq
MIRT1119092	hsa-miR-516b	CLIP-seq
MIRT1119113	hsa-miR-550a	CLIP-seq
MIRT2033705	hsa-miR-570	CLIP-seq
MIRT1119096	hsa-miR-571	CLIP-seq
MIRT2033706	hsa-miR-597	CLIP-seq
MIRT2033707	hsa-miR-668	CLIP-seq
MIRT2033708	hsa-miR-942	CLIP-seq
MIRT1119048	hsa-miR-106a	CLIP-seq
MIRT1119049	hsa-miR-106b	CLIP-seq
MIRT1119055	hsa-miR-17	CLIP-seq
MIRT1119057	hsa-miR-20a	CLIP-seq
MIRT1119058	hsa-miR-20b	CLIP-seq
MIRT1119093	hsa-miR-519d	CLIP-seq
MIRT1119105	hsa-miR-93	CLIP-seq
MIRT2264109	hsa-miR-1915	CLIP-seq
MIRT2264110	hsa-miR-4726-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8TCA0
• Protein name: Leucine-rich repeat-containing protein 20
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13855	LRR_8	51 → 109	Leucine rich repeat	Repeat
  PF13855	LRR_8	97 → 156	Leucine rich repeat	Repeat

• Sequence:

  MLKKMGEAVARVARKVNETVESGSDTLDLAECKLVSFPIGIYKVLRNVSGQIHLITLANN
  ELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALP
  ALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGAR
  APLP

• Sequence length: 184

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AUTISM SPECTRUM DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBSESSIVE-COMPULSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Lupus Erythematosus Systemic	Systemic lupus erythematosus	Pubtator	20659327	Associate	★☆☆☆☆ Found in Text Mining only