Gene Gene information from NCBI Gene database.
Entrez ID 55204
Gene name Golgi phosphoprotein 3 like
Gene symbol GOLPH3L
Synonyms (NCBI Gene)
GPP34R
Chromosome 1
Chromosome location 1q21.3
Summary The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefS
miRNA miRNA information provided by mirtarbase database.
718
miRTarBase ID miRNA Experiments Reference
MIRT000849 hsa-miR-15a-5p Microarray 18362358
MIRT000848 hsa-miR-16-5p Microarray 18362358
MIRT022020 hsa-miR-128-3p Microarray 17612493
MIRT567417 hsa-miR-302f PAR-CLIP 20371350
MIRT567416 hsa-miR-6840-3p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IC 23345592
GO:0005515 Function Protein binding IPI 23275563, 24705354, 25416956, 32814053
GO:0005794 Component Golgi apparatus IDA 11042173
GO:0005794 Component Golgi apparatus IEA
GO:0005802 Component Trans-Golgi network IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612208 24882 ENSG00000143457
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H4A5
Protein name Golgi phosphoprotein 3-like (GPP34-related protein)
Protein function Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05719 GPP34 48 274 Golgi phosphoprotein 3 (GPP34) Family
Sequence
Sequence length 285
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
27
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BILIARY TRACT CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Breast Neoplasms Breast neoplasm Pubtator 23172368 Associate
★☆☆☆☆
Found in Text Mining only
Carcinoma, Ovarian Epithelial Ovarian Epithelial carcinoma BEFREE 28978336
★☆☆☆☆
Found in Text Mining only
cervical cancer Cervical Cancer BEFREE 28261346
★☆☆☆☆
Found in Text Mining only
Cervix carcinoma Cervix carcinoma BEFREE 28261346
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of ovary Ovarian cancer BEFREE 28978336
★☆☆☆☆
Found in Text Mining only
Malignant tumor of cervix Cervical Tumor BEFREE 28261346
★☆☆☆☆
Found in Text Mining only
Ovarian Carcinoma Ovarian Carcinoma BEFREE 28978336
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ovarian neoplasm Ovarian neoplasm BEFREE 28978336
★☆☆☆☆
Found in Text Mining only
Prostate carcinoma Prostate cancer GWASCAT_DG 25217961, 26034056, 29892016
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Rhabdomyosarcoma Rhabdomyosarcoma BEFREE 21822541
★☆☆☆☆
Found in Text Mining only