Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	55119
Gene name	Pre-mRNA processing factor 38B
Gene symbol	PRPF38B
Synonyms (NCBI Gene)	NET1
Chromosome	1
Chromosome location	1p13.3

163

Show/Hide all (163)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027254	hsa-miR-101-3p	Sequencing	20371350
MIRT038040	hsa-miR-423-5p	CLASH	23622248
MIRT036833	hsa-miR-877-3p	CLASH	23622248
MIRT483517	hsa-miR-136-3p	PAR-CLIP	20371350
MIRT528633	hsa-miR-6073	PAR-CLIP	20371350
MIRT528632	hsa-miR-142-3p	PAR-CLIP	20371350
MIRT483517	hsa-miR-136-3p	PAR-CLIP	20371350
MIRT483517	hsa-miR-136-3p	PAR-CLIP	22012620
MIRT528633	hsa-miR-6073	PAR-CLIP	22012620
MIRT528632	hsa-miR-142-3p	PAR-CLIP	22012620
MIRT483517	hsa-miR-136-3p	PAR-CLIP	23592263
MIRT483517	hsa-miR-136-3p	PAR-CLIP	23592263
MIRT483517	hsa-miR-136-3p	PAR-CLIP	27292025
MIRT528632	hsa-miR-142-3p	PAR-CLIP	27292025
MIRT528633	hsa-miR-6073	PAR-CLIP	27292025
MIRT483517	hsa-miR-136-3p	PAR-CLIP	20371350
MIRT528633	hsa-miR-6073	PAR-CLIP	20371350
MIRT528632	hsa-miR-142-3p	PAR-CLIP	20371350
MIRT483517	hsa-miR-136-3p	PAR-CLIP	20371350
MIRT483517	hsa-miR-136-3p	PAR-CLIP	22012620
MIRT528633	hsa-miR-6073	PAR-CLIP	22012620
MIRT528632	hsa-miR-142-3p	PAR-CLIP	22012620
MIRT483517	hsa-miR-136-3p	PAR-CLIP	23592263
MIRT483517	hsa-miR-136-3p	PAR-CLIP	23592263
MIRT1265432	hsa-miR-101	CLIP-seq
MIRT1265433	hsa-miR-103a	CLIP-seq
MIRT1265434	hsa-miR-107	CLIP-seq
MIRT1265435	hsa-miR-1179	CLIP-seq
MIRT1265436	hsa-miR-1224-5p	CLIP-seq
MIRT1265437	hsa-miR-1228	CLIP-seq
MIRT1265438	hsa-miR-1248	CLIP-seq
MIRT1265439	hsa-miR-1275	CLIP-seq
MIRT1265440	hsa-miR-1283	CLIP-seq
MIRT1265441	hsa-miR-137	CLIP-seq
MIRT1265442	hsa-miR-144	CLIP-seq
MIRT1265443	hsa-miR-188-3p	CLIP-seq
MIRT1265444	hsa-miR-194	CLIP-seq
MIRT1265445	hsa-miR-200b	CLIP-seq
MIRT1265446	hsa-miR-200c	CLIP-seq
MIRT1265447	hsa-miR-2053	CLIP-seq
MIRT1265448	hsa-miR-216a	CLIP-seq
MIRT1265449	hsa-miR-217	CLIP-seq
MIRT1265450	hsa-miR-2276	CLIP-seq
MIRT1265451	hsa-miR-296-3p	CLIP-seq
MIRT1265452	hsa-miR-300	CLIP-seq
MIRT1265453	hsa-miR-3121-3p	CLIP-seq
MIRT1265454	hsa-miR-3146	CLIP-seq
MIRT1265455	hsa-miR-3148	CLIP-seq
MIRT1265456	hsa-miR-3150b-3p	CLIP-seq
MIRT1265457	hsa-miR-3189-5p	CLIP-seq
MIRT1265458	hsa-miR-34a	CLIP-seq
MIRT1265459	hsa-miR-34c-5p	CLIP-seq
MIRT1265460	hsa-miR-3613-3p	CLIP-seq
MIRT1265461	hsa-miR-3667-5p	CLIP-seq
MIRT1265462	hsa-miR-3677-5p	CLIP-seq
MIRT1265463	hsa-miR-374c	CLIP-seq
MIRT1265464	hsa-miR-381	CLIP-seq
MIRT1265465	hsa-miR-3915	CLIP-seq
MIRT1265466	hsa-miR-3973	CLIP-seq
MIRT1265467	hsa-miR-411	CLIP-seq
MIRT1265468	hsa-miR-4270	CLIP-seq
MIRT1265469	hsa-miR-4282	CLIP-seq
MIRT1265470	hsa-miR-429	CLIP-seq
MIRT1265471	hsa-miR-4297	CLIP-seq
MIRT1265472	hsa-miR-4310	CLIP-seq
MIRT1265473	hsa-miR-4418	CLIP-seq
MIRT1265474	hsa-miR-4436a	CLIP-seq
MIRT1265475	hsa-miR-4441	CLIP-seq
MIRT1265476	hsa-miR-4447	CLIP-seq
MIRT1265477	hsa-miR-4460	CLIP-seq
MIRT1265478	hsa-miR-4471	CLIP-seq
MIRT1265479	hsa-miR-4472	CLIP-seq
MIRT1265480	hsa-miR-4494	CLIP-seq
MIRT1265481	hsa-miR-449a	CLIP-seq
MIRT1265482	hsa-miR-449b	CLIP-seq
MIRT1265483	hsa-miR-4525	CLIP-seq
MIRT1265484	hsa-miR-4665-5p	CLIP-seq
MIRT1265485	hsa-miR-4666-3p	CLIP-seq
MIRT1265486	hsa-miR-4666-5p	CLIP-seq
MIRT1265487	hsa-miR-4668-5p	CLIP-seq
MIRT1265488	hsa-miR-4689	CLIP-seq
MIRT1265489	hsa-miR-4696	CLIP-seq
MIRT1265490	hsa-miR-4723-5p	CLIP-seq
MIRT1265491	hsa-miR-4727-3p	CLIP-seq
MIRT1265492	hsa-miR-4731-3p	CLIP-seq
MIRT1265493	hsa-miR-4758-3p	CLIP-seq
MIRT1265494	hsa-miR-4772-3p	CLIP-seq
MIRT1265495	hsa-miR-4777-5p	CLIP-seq
MIRT1265496	hsa-miR-4784	CLIP-seq
MIRT1265497	hsa-miR-4789-5p	CLIP-seq
MIRT1265498	hsa-miR-4801	CLIP-seq
MIRT1265499	hsa-miR-4802-3p	CLIP-seq
MIRT1265500	hsa-miR-489	CLIP-seq
MIRT1265501	hsa-miR-495	CLIP-seq
MIRT1265502	hsa-miR-500a	CLIP-seq
MIRT1265503	hsa-miR-509-3-5p	CLIP-seq
MIRT1265504	hsa-miR-509-5p	CLIP-seq
MIRT1265505	hsa-miR-514	CLIP-seq
MIRT1265506	hsa-miR-514b-3p	CLIP-seq
MIRT1265507	hsa-miR-518d-5p	CLIP-seq
MIRT1265508	hsa-miR-519b-5p	CLIP-seq
MIRT1265509	hsa-miR-519c-5p	CLIP-seq
MIRT1265510	hsa-miR-520c-5p	CLIP-seq
MIRT1265511	hsa-miR-526a	CLIP-seq
MIRT1265512	hsa-miR-544	CLIP-seq
MIRT1265513	hsa-miR-548a-5p	CLIP-seq
MIRT1265514	hsa-miR-548ab	CLIP-seq
MIRT1265515	hsa-miR-548ak	CLIP-seq
MIRT1265516	hsa-miR-548b-5p	CLIP-seq
MIRT1265517	hsa-miR-548c-5p	CLIP-seq
MIRT1265518	hsa-miR-548d-5p	CLIP-seq
MIRT1265519	hsa-miR-548h	CLIP-seq
MIRT1265520	hsa-miR-548i	CLIP-seq
MIRT1265521	hsa-miR-548j	CLIP-seq
MIRT1265522	hsa-miR-548w	CLIP-seq
MIRT1265523	hsa-miR-548y	CLIP-seq
MIRT1265524	hsa-miR-559	CLIP-seq
MIRT1265525	hsa-miR-569	CLIP-seq
MIRT1265526	hsa-miR-578	CLIP-seq
MIRT1265527	hsa-miR-606	CLIP-seq
MIRT1265528	hsa-miR-607	CLIP-seq
MIRT1265529	hsa-miR-625	CLIP-seq
MIRT1265530	hsa-miR-643	CLIP-seq
MIRT1265531	hsa-miR-655	CLIP-seq
MIRT1265532	hsa-miR-885-3p	CLIP-seq
MIRT1265533	hsa-miR-885-5p	CLIP-seq
MIRT1265534	hsa-miR-936	CLIP-seq
MIRT2078039	hsa-miR-186	CLIP-seq
MIRT1265452	hsa-miR-300	CLIP-seq
MIRT1265464	hsa-miR-381	CLIP-seq
MIRT1265433	hsa-miR-103a	CLIP-seq
MIRT1265434	hsa-miR-107	CLIP-seq
MIRT1265436	hsa-miR-1224-5p	CLIP-seq
MIRT1265449	hsa-miR-217	CLIP-seq
MIRT2304540	hsa-miR-3125	CLIP-seq
MIRT1265456	hsa-miR-3150b-3p	CLIP-seq
MIRT2304541	hsa-miR-3162-3p	CLIP-seq
MIRT2304542	hsa-miR-3646	CLIP-seq
MIRT2304543	hsa-miR-3647-3p	CLIP-seq
MIRT1265465	hsa-miR-3915	CLIP-seq
MIRT2304544	hsa-miR-3916	CLIP-seq
MIRT1265468	hsa-miR-4270	CLIP-seq
MIRT1265473	hsa-miR-4418	CLIP-seq
MIRT1265474	hsa-miR-4436a	CLIP-seq
MIRT1265475	hsa-miR-4441	CLIP-seq
MIRT1265488	hsa-miR-4689	CLIP-seq
MIRT1265496	hsa-miR-4784	CLIP-seq
MIRT1265503	hsa-miR-509-3-5p	CLIP-seq
MIRT1265504	hsa-miR-509-5p	CLIP-seq
MIRT2304545	hsa-miR-583	CLIP-seq
MIRT1265527	hsa-miR-606	CLIP-seq
MIRT2601535	hsa-miR-1297	CLIP-seq
MIRT2601536	hsa-miR-26a	CLIP-seq
MIRT2601537	hsa-miR-26b	CLIP-seq
MIRT2601538	hsa-miR-2861	CLIP-seq
MIRT2601539	hsa-miR-3913-3p	CLIP-seq
MIRT2601540	hsa-miR-4465	CLIP-seq
MIRT1265478	hsa-miR-4471	CLIP-seq
MIRT2601541	hsa-miR-4757-5p	CLIP-seq
MIRT2601542	hsa-miR-4769-3p	CLIP-seq
MIRT1265500	hsa-miR-489	CLIP-seq
MIRT2601543	hsa-miR-576-5p	CLIP-seq
MIRT2601544	hsa-miR-630	CLIP-seq

Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674
GO:0005634	Component	Nucleus	IEA
GO:0005681	Component	Spliceosomal complex	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0071011	Component	Precatalytic spliceosome	IBA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q5VTL8

Protein name

Pre-mRNA-splicing factor 38B (Sarcoma antigen NY-SAR-27)

Protein function

May be required for pre-mRNA splicing.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03371	PRP38	47 → 231	PRP38 family	Family

Sequence

MANNSPALTGNSQPQHQAAAAAAQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNP
MILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVG
TGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFES
FLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKI
KKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKE
RQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKEN
ERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSK
KEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTD
SVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHK
NKDETV

Sequence length

546

Interactions

View interactions

	KEGG
	Spliceosome

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
High myopia	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NASOPHARYNGEAL NEOPLASM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEVERE MYOPIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (40)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	31046876		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	LHGDN	16552434		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	BEFREE	21857017, 24375299, 24596379		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Acute Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	31046876		★★★★★ ★☆☆☆☆ Found in Text Mining only
Attention Deficit Disorder with Hyperactivity	Attention deficit hyperactivity disorder	Pubtator	20039948	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Attention deficit hyperactivity disorder	Attention Deficit Hyperactivity Disorder	BEFREE	15717291, 17994190, 20039948, 23872233		★★★★★ ★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Barrett esophagus	BEFREE	23945136		★★★★★ ★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Barrett esophagus	Pubtator	23945136	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	29620229		★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain Neoplasms	BEFREE	21979892		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	19124484, 20406972, 21857017, 21986943, 24596379, 29348822, 29769144		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	19124484, 23380069, 23689132, 24897521, 30332929	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	12115476		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	20590388, 24885292, 27216880, 31128017, 32641699, 36458010	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	29620229		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervical Intraepithelial Neoplasia	Cervical Intraepithelial Neoplasia	BEFREE	12115476		★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	BEFREE	31046876		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dentinogenesis Imperfecta	Dentinogenesis Imperfecta	BEFREE	19029076		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastric Adenocarcinoma	Gastric Cancer	BEFREE	16552434, 18827818, 23945136, 24375299		★★★★★ ★☆☆☆☆ Found in Text Mining only
Invasive Ductal Breast Carcinoma	Invasive Duct and Lobular Carcinoma	BEFREE	29348822		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	18214716, 22378020, 23636606, 25113254, 27216880, 30301500, 30867719, 31544556		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	18214716		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	32420320, 33955315	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	19124484, 20406972, 21857017, 21986943, 24596379, 29348822, 29769144		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	23945136		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of gastrointestinal tract	Malignant gastrointestinal tract tumors	BEFREE	24375299		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	16552434, 18827818, 21284875, 31451992		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	29620229		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	23184663, 24375299, 26080853, 28511963, 29695506, 29769144, 31046876, 31088838		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	19124484		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	16552434, 18827818, 21979892, 24375299, 28511963, 29769144, 30301500, 31544556, 31657628		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	26459749		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	34001978	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor Cell Lymphoblastic Leukemia Lymphoma	Lymphoblastic Leukemia	BEFREE	31046876		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of skin	Skin carcinoma	BEFREE	24196235, 26080853		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	16552434, 18827818, 21284875, 31451992		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	16552434, 21284875, 23945136	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	18827818	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Subarachnoid Hemorrhage	Subarachnoid hemorrhage	BEFREE	30531151		★★★★★ ★☆☆☆☆ Found in Text Mining only

PRPF38B (pre-mRNA processing factor 38B)