Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	55088
Gene name	Coiled-coil domain containing 186
Gene symbol	CCDC186
Synonyms (NCBI Gene)	C10orf118CCCP-1CCCP1golgin104
Chromosome	10
Chromosome location	10q25.3

Show/Hide all (45)

miRTarBase ID	miRNA	Experiments	Reference
MIRT728170	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT728169	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT728168	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT740657	hsa-miR-8485	HITS-CLIP	21572407
MIRT740658	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT740659	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT740660	hsa-miR-603	HITS-CLIP	21572407
MIRT740661	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT740662	hsa-miR-6834-3p	HITS-CLIP	21572407
MIRT740663	hsa-miR-3941	HITS-CLIP	21572407
MIRT740664	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT740665	hsa-let-7c-3p	HITS-CLIP	21572407
MIRT742190	hsa-miR-338-5p	HITS-CLIP	23824327
MIRT740657	hsa-miR-8485	HITS-CLIP	23824327
MIRT740658	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT740659	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT740660	hsa-miR-603	HITS-CLIP	23824327
MIRT740661	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT742191	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT740663	hsa-miR-3941	HITS-CLIP	23824327
MIRT740664	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT742190	hsa-miR-338-5p	HITS-CLIP	23824327
MIRT740657	hsa-miR-8485	HITS-CLIP	23824327
MIRT740658	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT740659	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT740660	hsa-miR-603	HITS-CLIP	23824327
MIRT740661	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT742191	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT740662	hsa-miR-6834-3p	HITS-CLIP	23824327
MIRT742373	hsa-miR-3909	HITS-CLIP	23824327
MIRT742374	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT740663	hsa-miR-3941	HITS-CLIP	23824327
MIRT740664	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT742375	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT740665	hsa-let-7c-3p	HITS-CLIP	23824327
MIRT742190	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT740657	hsa-miR-8485	PAR-CLIP	21572407
MIRT740658	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT740659	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT740660	hsa-miR-603	PAR-CLIP	21572407
MIRT740661	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT742191	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT740663	hsa-miR-3941	PAR-CLIP	21572407
MIRT740664	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT740665	hsa-let-7c-3p	PAR-CLIP	21572407

Show/Hide all (8)

GO ID	Ontology	Definition	Evidence
GO:0005794	Component	Golgi apparatus	IEA
GO:0005802	Component	Trans-Golgi network	IBA
GO:0009617	Process	Response to bacterium	IEA
GO:0031267	Function	Small GTPase binding	IBA
GO:0035773	Process	Insulin secretion involved in cellular response to glucose stimulus	IEA
GO:0042593	Process	Glucose homeostasis	IEA
GO:0099518	Process	Vesicle cytoskeletal trafficking	IBA
GO:0099518	Process	Vesicle cytoskeletal trafficking	IEA

MIM	HGNC	e!Ensembl
619249	24349	ENSG00000165813

Q7Z3E2

Protein name

Coiled-coil domain-containing protein 186 (CTCL tumor antigen HD-CL-01/L14-2)

Family and domains

Sequence

MSETDHIASTSSDKNVGKTPELKEDSCNLFSGNESSKLENESKLLSLNTDKTLCQPNEHN
NRIEAQENYIPDHGGGEDSCAKTDTGSENSEQIANFPSGNFAKHISKTNETEQKVTQILV
ELRSSTFPESANEKTYSESPYDTDCTKKFISKIKSVSASEDLLEEIESELLSTEFAEHRV
PNGMNKGEHALVLFEKCVQDKYLQQEHIIKKLIKENKKHQELFVDICSEKDNLREELKKR
TETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKK
CEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRL
HQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKL
TQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAK
IKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKV
KTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNA
QLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELA
CRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSM
GSRSSSSGSLNARSSAEDRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIE
FMEDHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPA
DNGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKT

Sequence length

898

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
HYPOTHYROIDISM	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (10)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Atrophy	Atrophy	Pubtator	37569695	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Diseases	Brain disease	Pubtator	33259146	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	35508649	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Central Nervous System Diseases	Central nervous system disease	Pubtator	37569695	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Demyelinating Diseases	Demyelinating diseases	Pubtator	37569695	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	33259146, 37569695	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Endocrine System Diseases	Endocrine system disease	Pubtator	37569695	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoglycemia	Hypoglycemia	Pubtator	37569695	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malpuech facial clefting syndrome	Malpuech facial clefting syndrome	Pubtator	37569695	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Seizures	Seizures	Pubtator	37569695	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

CCDC186 (coiled-coil domain containing 186)