TUG1 (taurine up-regulated 1)

Gene Gene information from NCBI Gene database.
Gene miRNA Other IDs Protein Associated diseases
Entrez ID 55000
Gene name Taurine up-regulated 1
Gene symbol TUG1
Synonyms (NCBI Gene)
LINC00080NCRNA00080TI-227H
Chromosome 22
Chromosome location 22q12.2
Summary This gene produces a long non-coding RNA that interacts with the Polycomb repressor complex and functions in the epigenetic regulation of transcription. This RNA promotes cell proliferation and is upregulated in tumor cells. It may act as a sponge for mic
miRNA miRNA information provided by mirtarbase database.
5
Gene miRNA Other IDs Protein Associated diseases
Show/Hide all (5)
miRTarBase ID miRNA Experiments Reference
MIRT732971 hsa-miR-9-5p Luciferase reporter assayqRT-PCRWestern blotting 33380806
MIRT734096 hsa-miR-1299 ImmunofluorescenceLuciferase reporter assayqRT-PCRWestern blotting 32468036
MIRT734096 hsa-miR-1299 ImmunofluorescenceLuciferase reporter assayqRT-PCRWestern blotting 32468036
MIRT732971 hsa-miR-9-5p Luciferase reporter assayWestern blottingqRT-PCR 33380806
MIRT755491 hsa-miR-582-3p Luciferase reporter assayWestern blottingqRT-PCR 34793263
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
614971 26066 ENSG00000253352
Protein Protein information from UniProt database.
Gene miRNA Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A0A6I8PU40
Protein name Taurine up-regulated 1 protein
Family and domains
Tissue specificity TISSUE SPECIFICITY: Ubiquitous (PubMed:32894169). Highly expressed in testis (PubMed:32894169). {ECO:0000269|PubMed:32894169}.
Sequence 


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Sequence length
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Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Gene miRNA Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (3)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BULIMIA NERVOSA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS — CTD, Disgenet
CTD, Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (181)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute monocytic leukemia Monocytic Leukemia BEFREE 29654398
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of lung (disorder) Lung adenocarcinoma BEFREE 29254212
★★★★★
★☆☆☆☆
Found in Text Mining only
Adult Acute Myeloblastic Leukemia Myeloblastic Leukemia BEFREE 29654398
★★★★★
★☆☆☆☆
Found in Text Mining only
Ankylosing spondylitis Ankylosing Spondylitis BEFREE 30146549, 31815638
★★★★★
★☆☆☆☆
Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA Syndromic microphthalmia BEFREE 29960845
★★★★★
★☆☆☆☆
Found in Text Mining only
Aortic valve calcification Aortic valve calcification BEFREE 29016735
★★★★★
★☆☆☆☆
Found in Text Mining only
Arteriosclerosis Arteriosclerosis BEFREE 29016735, 29268138, 30402858, 30468492, 31355277
★★★★★
★☆☆☆☆
Found in Text Mining only
Arthritis Rheumatoid Rheumatoid arthritis Pubtator 34403518 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Asthma Asthma BEFREE 31217885
★★★★★
★☆☆☆☆
Found in Text Mining only
Asthma Asthma Pubtator 34335559, 34749662 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only