Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	54940
Gene name	OCIA domain containing 1
Gene symbol	OCIAD1
Synonyms (NCBI Gene)	ASRIJOCIATPA018
Chromosome	4
Chromosome location	4p11

225

Show/Hide all (225)

miRTarBase ID	miRNA	Experiments	Reference
MIRT683894	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT683893	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT683892	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT683891	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT683890	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT683889	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT683888	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT683887	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT683886	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT683885	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT683884	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT683883	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT683882	hsa-miR-302e	HITS-CLIP	23313552
MIRT683881	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT683880	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT683879	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT683878	hsa-miR-520b	HITS-CLIP	23313552
MIRT683877	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT683876	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT683875	hsa-miR-520e	HITS-CLIP	23313552
MIRT683874	hsa-miR-4438	HITS-CLIP	23313552
MIRT683873	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT683872	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT683871	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT683870	hsa-miR-520h	HITS-CLIP	23313552
MIRT683869	hsa-miR-6890-3p	HITS-CLIP	23313552
MIRT683868	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT683867	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT683866	hsa-miR-1234-3p	HITS-CLIP	23313552
MIRT683865	hsa-miR-7107-5p	HITS-CLIP	23313552
MIRT683864	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT683863	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT683862	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT683861	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT683860	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT683859	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT683858	hsa-miR-5095	HITS-CLIP	23313552
MIRT683857	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT683856	hsa-miR-4665-3p	HITS-CLIP	23313552
MIRT683855	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT527494	hsa-miR-548g-3p	PAR-CLIP	22012620
MIRT527493	hsa-miR-300	PAR-CLIP	22012620
MIRT527492	hsa-miR-381-3p	PAR-CLIP	22012620
MIRT527491	hsa-miR-4666a-3p	PAR-CLIP	22012620
MIRT527490	hsa-miR-4719	PAR-CLIP	22012620
MIRT527489	hsa-miR-6841-3p	PAR-CLIP	22012620
MIRT527488	hsa-miR-938	PAR-CLIP	22012620
MIRT527487	hsa-miR-6886-3p	PAR-CLIP	22012620
MIRT527486	hsa-let-7a-3p	PAR-CLIP	22012620
MIRT527485	hsa-let-7b-3p	PAR-CLIP	22012620
MIRT527484	hsa-let-7f-1-3p	PAR-CLIP	22012620
MIRT527483	hsa-miR-98-3p	PAR-CLIP	22012620
MIRT527482	hsa-miR-513b-5p	PAR-CLIP	22012620
MIRT527481	hsa-miR-3157-3p	PAR-CLIP	22012620
MIRT527480	hsa-miR-874-3p	PAR-CLIP	22012620
MIRT527486	hsa-let-7a-3p	PAR-CLIP	26701625
MIRT527486	hsa-let-7a-3p	PAR-CLIP	26701625
MIRT527486	hsa-let-7a-3p	PAR-CLIP	26701625
MIRT527485	hsa-let-7b-3p	PAR-CLIP	26701625
MIRT527485	hsa-let-7b-3p	PAR-CLIP	26701625
MIRT527485	hsa-let-7b-3p	PAR-CLIP	26701625
MIRT527484	hsa-let-7f-1-3p	PAR-CLIP	26701625
MIRT527484	hsa-let-7f-1-3p	PAR-CLIP	26701625
MIRT527484	hsa-let-7f-1-3p	PAR-CLIP	26701625
MIRT527493	hsa-miR-300	PAR-CLIP	26701625
MIRT527493	hsa-miR-300	PAR-CLIP	26701625
MIRT527493	hsa-miR-300	PAR-CLIP	26701625
MIRT527492	hsa-miR-381-3p	PAR-CLIP	26701625
MIRT527492	hsa-miR-381-3p	PAR-CLIP	26701625
MIRT527492	hsa-miR-381-3p	PAR-CLIP	26701625
MIRT527491	hsa-miR-4666a-3p	PAR-CLIP	26701625
MIRT527491	hsa-miR-4666a-3p	PAR-CLIP	26701625
MIRT527491	hsa-miR-4666a-3p	PAR-CLIP	26701625
MIRT527490	hsa-miR-4719	PAR-CLIP	26701625
MIRT527490	hsa-miR-4719	PAR-CLIP	26701625
MIRT527490	hsa-miR-4719	PAR-CLIP	26701625
MIRT527482	hsa-miR-513b-5p	PAR-CLIP	26701625
MIRT527482	hsa-miR-513b-5p	PAR-CLIP	26701625
MIRT527482	hsa-miR-513b-5p	PAR-CLIP	26701625
MIRT527494	hsa-miR-548g-3p	PAR-CLIP	26701625
MIRT527494	hsa-miR-548g-3p	PAR-CLIP	26701625
MIRT527494	hsa-miR-548g-3p	PAR-CLIP	26701625
MIRT527483	hsa-miR-98-3p	PAR-CLIP	26701625
MIRT527483	hsa-miR-98-3p	PAR-CLIP	26701625
MIRT527483	hsa-miR-98-3p	PAR-CLIP	26701625
MIRT683894	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT683893	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT683892	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT683891	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT683890	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT683889	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT683888	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT683887	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT683886	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT683885	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT683884	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT683883	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT683882	hsa-miR-302e	HITS-CLIP	23313552
MIRT683881	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT683880	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT683879	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT683878	hsa-miR-520b	HITS-CLIP	23313552
MIRT683877	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT683876	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT683875	hsa-miR-520e	HITS-CLIP	23313552
MIRT683874	hsa-miR-4438	HITS-CLIP	23313552
MIRT683873	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT683872	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT683871	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT683870	hsa-miR-520h	HITS-CLIP	23313552
MIRT683869	hsa-miR-6890-3p	HITS-CLIP	23313552
MIRT683868	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT683867	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT683866	hsa-miR-1234-3p	HITS-CLIP	23313552
MIRT683865	hsa-miR-7107-5p	HITS-CLIP	23313552
MIRT683864	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT683863	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT683862	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT683861	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT683860	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT683859	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT683858	hsa-miR-5095	HITS-CLIP	23313552
MIRT683857	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT683856	hsa-miR-4665-3p	HITS-CLIP	23313552
MIRT683855	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT527494	hsa-miR-548g-3p	PAR-CLIP	22012620
MIRT527493	hsa-miR-300	PAR-CLIP	22012620
MIRT527492	hsa-miR-381-3p	PAR-CLIP	22012620
MIRT527491	hsa-miR-4666a-3p	PAR-CLIP	22012620
MIRT527490	hsa-miR-4719	PAR-CLIP	22012620
MIRT527489	hsa-miR-6841-3p	PAR-CLIP	22012620
MIRT527488	hsa-miR-938	PAR-CLIP	22012620
MIRT527487	hsa-miR-6886-3p	PAR-CLIP	22012620
MIRT527486	hsa-let-7a-3p	PAR-CLIP	22012620
MIRT527485	hsa-let-7b-3p	PAR-CLIP	22012620
MIRT527484	hsa-let-7f-1-3p	PAR-CLIP	22012620
MIRT527483	hsa-miR-98-3p	PAR-CLIP	22012620
MIRT527482	hsa-miR-513b-5p	PAR-CLIP	22012620
MIRT527481	hsa-miR-3157-3p	PAR-CLIP	22012620
MIRT527480	hsa-miR-874-3p	PAR-CLIP	22012620
MIRT1201774	hsa-miR-1243	CLIP-seq
MIRT1201775	hsa-miR-200b	CLIP-seq
MIRT1201776	hsa-miR-200c	CLIP-seq
MIRT1201777	hsa-miR-3654	CLIP-seq
MIRT1201778	hsa-miR-369-3p	CLIP-seq
MIRT1201779	hsa-miR-374c	CLIP-seq
MIRT1201780	hsa-miR-429	CLIP-seq
MIRT1201781	hsa-miR-4434	CLIP-seq
MIRT1201782	hsa-miR-4516	CLIP-seq
MIRT1201783	hsa-miR-4531	CLIP-seq
MIRT1201784	hsa-miR-4659a-5p	CLIP-seq
MIRT1201785	hsa-miR-4659b-5p	CLIP-seq
MIRT1201786	hsa-miR-4662a-3p	CLIP-seq
MIRT1201787	hsa-miR-4776-3p	CLIP-seq
MIRT1201788	hsa-miR-655	CLIP-seq
MIRT1201789	hsa-miR-2054	CLIP-seq
MIRT1201790	hsa-miR-216a	CLIP-seq
MIRT1201791	hsa-miR-216b	CLIP-seq
MIRT1201792	hsa-miR-2278	CLIP-seq
MIRT1201793	hsa-miR-3658	CLIP-seq
MIRT1201794	hsa-miR-4326	CLIP-seq
MIRT1201795	hsa-miR-4446-3p	CLIP-seq
MIRT1201796	hsa-miR-4675	CLIP-seq
MIRT1201797	hsa-miR-4684-3p	CLIP-seq
MIRT1201798	hsa-miR-4687-3p	CLIP-seq
MIRT1201799	hsa-miR-4721	CLIP-seq
MIRT1201800	hsa-miR-4728-3p	CLIP-seq
MIRT1201801	hsa-miR-4741	CLIP-seq
MIRT1201802	hsa-miR-4777-5p	CLIP-seq
MIRT1201803	hsa-miR-518d-5p	CLIP-seq
MIRT1201804	hsa-miR-519b-5p	CLIP-seq
MIRT1201805	hsa-miR-519c-5p	CLIP-seq
MIRT1201806	hsa-miR-520c-5p	CLIP-seq
MIRT1201807	hsa-miR-526a	CLIP-seq
MIRT2058228	hsa-miR-106a	CLIP-seq
MIRT2058229	hsa-miR-106b	CLIP-seq
MIRT2058230	hsa-miR-17	CLIP-seq
MIRT2058231	hsa-miR-20a	CLIP-seq
MIRT2058232	hsa-miR-20b	CLIP-seq
MIRT2058233	hsa-miR-2681	CLIP-seq
MIRT2058234	hsa-miR-302a	CLIP-seq
MIRT2058235	hsa-miR-302b	CLIP-seq
MIRT2058236	hsa-miR-302c	CLIP-seq
MIRT2058237	hsa-miR-302d	CLIP-seq
MIRT1201778	hsa-miR-369-3p	CLIP-seq
MIRT2058238	hsa-miR-372	CLIP-seq
MIRT2058239	hsa-miR-373	CLIP-seq
MIRT2058240	hsa-miR-374a	CLIP-seq
MIRT2058241	hsa-miR-374b	CLIP-seq
MIRT2058242	hsa-miR-381	CLIP-seq
MIRT2058243	hsa-miR-4666-3p	CLIP-seq
MIRT2058244	hsa-miR-4775	CLIP-seq
MIRT2058245	hsa-miR-513b	CLIP-seq
MIRT2058246	hsa-miR-519d	CLIP-seq
MIRT2058247	hsa-miR-520g	CLIP-seq
MIRT2058248	hsa-miR-548g	CLIP-seq
MIRT2058249	hsa-miR-590-3p	CLIP-seq
MIRT2058250	hsa-miR-874	CLIP-seq
MIRT2058251	hsa-miR-93	CLIP-seq
MIRT2286627	hsa-miR-205	CLIP-seq
MIRT2058233	hsa-miR-2681	CLIP-seq
MIRT1201778	hsa-miR-369-3p	CLIP-seq
MIRT2058240	hsa-miR-374a	CLIP-seq
MIRT2058241	hsa-miR-374b	CLIP-seq
MIRT2058242	hsa-miR-381	CLIP-seq
MIRT2058243	hsa-miR-4666-3p	CLIP-seq
MIRT2286628	hsa-miR-4738-3p	CLIP-seq
MIRT2391859	hsa-miR-150	CLIP-seq
MIRT2455589	hsa-miR-1182	CLIP-seq
MIRT2455590	hsa-miR-4315	CLIP-seq
MIRT2455591	hsa-miR-4423-5p	CLIP-seq
MIRT2455592	hsa-miR-4790-5p	CLIP-seq
MIRT2455593	hsa-miR-720	CLIP-seq
MIRT2286627	hsa-miR-205	CLIP-seq
MIRT2584927	hsa-miR-3171	CLIP-seq
MIRT2584928	hsa-miR-380	CLIP-seq
MIRT2286628	hsa-miR-4738-3p	CLIP-seq
MIRT2058244	hsa-miR-4775	CLIP-seq
MIRT2058249	hsa-miR-590-3p	CLIP-seq
MIRT2286627	hsa-miR-205	CLIP-seq
MIRT2584927	hsa-miR-3171	CLIP-seq
MIRT2584928	hsa-miR-380	CLIP-seq
MIRT2286628	hsa-miR-4738-3p	CLIP-seq
MIRT2058244	hsa-miR-4775	CLIP-seq
MIRT2058249	hsa-miR-590-3p	CLIP-seq

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	20195357, 29743632, 32296183, 33961781
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005764	Component	Lysosome	ISS
GO:0005768	Component	Endosome	IBA
GO:0005768	Component	Endosome	IEA
GO:0005768	Component	Endosome	ISS
GO:0005794	Component	Golgi apparatus	ISS
GO:0006897	Process	Endocytosis	ISS
GO:0016020	Component	Membrane	HDA	19946888
GO:0046427	Process	Positive regulation of receptor signaling pathway via JAK-STAT	ISS
GO:0061484	Process	Hematopoietic stem cell homeostasis	ISS
GO:2000736	Process	Regulation of stem cell differentiation	IEA
GO:2000736	Process	Regulation of stem cell differentiation	ISS

MIM	HGNC	e!Ensembl
619596	16074	ENSG00000109180

Q9NX40

Protein name

OCIA domain-containing protein 1 (Ovarian cancer immunoreactive antigen domain containing 1) (Ovarian carcinoma immunoreactive antigen)

Protein function

Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated canc

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07051	OCIA	23 → 109	Ovarian carcinoma immunoreactive antigen (OCIA)	Family

Tissue specificity

TISSUE SPECIFICITY: Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord. {ECO:000

Sequence

MNGRADFREPNAEVPRPIPHIGPDYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQG
LISKGILSSHPKYGSIPKLILACIMGYFAGKLSYVKTCQEKFKKLENSPLGEALRSGQAR
RSSPPGHYYQKSKYDSSVSGQSSFVTSPAADNIEMLPHYEPIPFSSSMNESAPTGITDHI
VQGPDPNLEESPKRKNITYEELRNKNRESYEVSLTQKTDPSVRPMHERVPKKEVKVNKYG
DTWDE

Sequence length

245

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BREAST CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (12)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	31221523		★★★★★ ★☆☆☆☆ Found in Text Mining only
Corneal Neovascularization	Corneal neovascularization	Pubtator	36579659	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hepatitis C Chronic	Hepatitis c	Pubtator	32697788	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	31221523		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	31221523		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Mitochondrial disease	Pubtator	34034859	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	29743632		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oestrogen receptor positive breast cancer	Oestrogen Receptor Positive Breast Cancer	BEFREE	26958999		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	LHGDN	18328549		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	31221523		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Ductal Adenocarcinoma	Pancreatic adenocarcinoma	BEFREE	31221523		★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	36595859	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

OCIAD1 (OCIA domain containing 1)