UBE2R2 (ubiquitin conjugating enzyme E2 R2)

Gene

• Entrez ID: 54926
• Gene name: Ubiquitin conjugating enzyme E2 R2
• Gene symbol: UBE2R2
• Synonyms (NCBI Gene): CDC34B, E2-CDC34B, UBC3B
• Chromosome: 9
• Chromosome location: 9p13.3
• Summary: Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT023173	hsa-miR-124-3p	Microarray	18668037
MIRT025944	hsa-miR-7-5p	Microarray	19073608
MIRT027175	hsa-miR-103a-3p	Sequencing	20371350
MIRT049547	hsa-miR-92a-3p	CLASH	23622248
MIRT038898	hsa-miR-93-3p	CLASH	23622248
MIRT1468732	hsa-miR-1238	CLIP-seq
MIRT1468733	hsa-miR-1245	CLIP-seq
MIRT1468734	hsa-miR-1257	CLIP-seq
MIRT1468735	hsa-miR-1266	CLIP-seq
MIRT1468736	hsa-miR-1279	CLIP-seq
MIRT1468737	hsa-miR-129-5p	CLIP-seq
MIRT1468738	hsa-miR-1299	CLIP-seq
MIRT1468739	hsa-miR-182	CLIP-seq
MIRT1468740	hsa-miR-186	CLIP-seq
MIRT1468741	hsa-miR-188-3p	CLIP-seq
MIRT1468742	hsa-miR-197	CLIP-seq
MIRT1468743	hsa-miR-214	CLIP-seq
MIRT1468744	hsa-miR-2355-5p	CLIP-seq
MIRT1468745	hsa-miR-23a	CLIP-seq
MIRT1468746	hsa-miR-23b	CLIP-seq
MIRT1468747	hsa-miR-23c	CLIP-seq
MIRT1468748	hsa-miR-28-5p	CLIP-seq
MIRT1468749	hsa-miR-3133	CLIP-seq
MIRT1468750	hsa-miR-3134	CLIP-seq
MIRT1468751	hsa-miR-3139	CLIP-seq
MIRT1468752	hsa-miR-3189-5p	CLIP-seq
MIRT1468753	hsa-miR-3591-3p	CLIP-seq
MIRT1468754	hsa-miR-3619-5p	CLIP-seq
MIRT1468755	hsa-miR-3646	CLIP-seq
MIRT1468756	hsa-miR-365	CLIP-seq
MIRT1468757	hsa-miR-3664-3p	CLIP-seq
MIRT1468758	hsa-miR-3675-5p	CLIP-seq
MIRT1468759	hsa-miR-3679-3p	CLIP-seq
MIRT1468760	hsa-miR-3682-5p	CLIP-seq
MIRT1468761	hsa-miR-371b-5p	CLIP-seq
MIRT1468762	hsa-miR-3936	CLIP-seq
MIRT1468763	hsa-miR-3940-5p	CLIP-seq
MIRT1468764	hsa-miR-3973	CLIP-seq
MIRT1468765	hsa-miR-411	CLIP-seq
MIRT1468766	hsa-miR-4270	CLIP-seq
MIRT1468767	hsa-miR-4283	CLIP-seq
MIRT1468768	hsa-miR-4286	CLIP-seq
MIRT1468769	hsa-miR-4291	CLIP-seq
MIRT1468770	hsa-miR-4292	CLIP-seq
MIRT1468771	hsa-miR-4308	CLIP-seq
MIRT1468772	hsa-miR-4321	CLIP-seq
MIRT1468773	hsa-miR-4441	CLIP-seq
MIRT1468774	hsa-miR-4446-3p	CLIP-seq
MIRT1468775	hsa-miR-4464	CLIP-seq
MIRT1468776	hsa-miR-4468	CLIP-seq
MIRT1468777	hsa-miR-4470	CLIP-seq
MIRT1468778	hsa-miR-4489	CLIP-seq
MIRT1468779	hsa-miR-4495	CLIP-seq
MIRT1468780	hsa-miR-4496	CLIP-seq
MIRT1468781	hsa-miR-4507	CLIP-seq
MIRT1468782	hsa-miR-4518	CLIP-seq
MIRT1468783	hsa-miR-4534	CLIP-seq
MIRT1468784	hsa-miR-4656	CLIP-seq
MIRT1468785	hsa-miR-4663	CLIP-seq
MIRT1468786	hsa-miR-4672	CLIP-seq
MIRT1468787	hsa-miR-4691-5p	CLIP-seq
MIRT1468788	hsa-miR-4698	CLIP-seq
MIRT1468789	hsa-miR-4722-5p	CLIP-seq
MIRT1468790	hsa-miR-4733-5p	CLIP-seq
MIRT1468791	hsa-miR-4748	CLIP-seq
MIRT1468792	hsa-miR-4758-3p	CLIP-seq
MIRT1468793	hsa-miR-4766-5p	CLIP-seq
MIRT1468794	hsa-miR-488	CLIP-seq
MIRT1468795	hsa-miR-515-5p	CLIP-seq
MIRT1468796	hsa-miR-520d-5p	CLIP-seq
MIRT1468797	hsa-miR-521	CLIP-seq
MIRT1468798	hsa-miR-524-5p	CLIP-seq
MIRT1468799	hsa-miR-532-3p	CLIP-seq
MIRT1468800	hsa-miR-548l	CLIP-seq
MIRT1468801	hsa-miR-548m	CLIP-seq
MIRT1468802	hsa-miR-561	CLIP-seq
MIRT1468803	hsa-miR-603	CLIP-seq
MIRT1468804	hsa-miR-628-5p	CLIP-seq
MIRT1468805	hsa-miR-634	CLIP-seq
MIRT1468806	hsa-miR-646	CLIP-seq
MIRT1468807	hsa-miR-671-5p	CLIP-seq
MIRT1468808	hsa-miR-708	CLIP-seq
MIRT1468809	hsa-miR-761	CLIP-seq
MIRT1468810	hsa-miR-875-3p	CLIP-seq
MIRT1468811	hsa-miR-922	CLIP-seq
MIRT1555319	hsa-miR-4731-5p	CLIP-seq
MIRT1468803	hsa-miR-603	CLIP-seq
MIRT2140803	hsa-miR-103a	CLIP-seq
MIRT2140804	hsa-miR-107	CLIP-seq
MIRT2140805	hsa-miR-1206	CLIP-seq
MIRT1468732	hsa-miR-1238	CLIP-seq
MIRT2140806	hsa-miR-1270	CLIP-seq
MIRT2140807	hsa-miR-1273f	CLIP-seq
MIRT2140808	hsa-miR-1291	CLIP-seq
MIRT2140809	hsa-miR-1297	CLIP-seq
MIRT2140810	hsa-miR-1323	CLIP-seq
MIRT2140811	hsa-miR-146b-3p	CLIP-seq
MIRT2140812	hsa-miR-150	CLIP-seq
MIRT1468743	hsa-miR-214	CLIP-seq
MIRT2140813	hsa-miR-26a	CLIP-seq
MIRT2140814	hsa-miR-26b	CLIP-seq
MIRT1468748	hsa-miR-28-5p	CLIP-seq
MIRT1468751	hsa-miR-3139	CLIP-seq
MIRT2140815	hsa-miR-3155	CLIP-seq
MIRT2140816	hsa-miR-3155b	CLIP-seq
MIRT2140817	hsa-miR-3183	CLIP-seq
MIRT2140818	hsa-miR-328	CLIP-seq
MIRT2140819	hsa-miR-33a	CLIP-seq
MIRT2140820	hsa-miR-33b	CLIP-seq
MIRT2140821	hsa-miR-3545-5p	CLIP-seq
MIRT2140822	hsa-miR-3611	CLIP-seq
MIRT1468754	hsa-miR-3619-5p	CLIP-seq
MIRT1468755	hsa-miR-3646	CLIP-seq
MIRT2140823	hsa-miR-3649	CLIP-seq
MIRT2140824	hsa-miR-3671	CLIP-seq
MIRT2140825	hsa-miR-3691-3p	CLIP-seq
MIRT1468762	hsa-miR-3936	CLIP-seq
MIRT2140826	hsa-miR-4271	CLIP-seq
MIRT1468769	hsa-miR-4291	CLIP-seq
MIRT1468774	hsa-miR-4446-3p	CLIP-seq
MIRT2140827	hsa-miR-4465	CLIP-seq
MIRT1468779	hsa-miR-4495	CLIP-seq
MIRT1468784	hsa-miR-4656	CLIP-seq
MIRT2140828	hsa-miR-4680-5p	CLIP-seq
MIRT2140829	hsa-miR-4683	CLIP-seq
MIRT2140830	hsa-miR-4709-5p	CLIP-seq
MIRT2140831	hsa-miR-4713-5p	CLIP-seq
MIRT1468789	hsa-miR-4722-5p	CLIP-seq
MIRT2140832	hsa-miR-4723-3p	CLIP-seq
MIRT2140833	hsa-miR-4725-3p	CLIP-seq
MIRT1555319	hsa-miR-4731-5p	CLIP-seq
MIRT1468793	hsa-miR-4766-5p	CLIP-seq
MIRT2140834	hsa-miR-4802-3p	CLIP-seq
MIRT2140835	hsa-miR-484	CLIP-seq
MIRT2140836	hsa-miR-519a	CLIP-seq
MIRT2140837	hsa-miR-519b-3p	CLIP-seq
MIRT2140838	hsa-miR-519c-3p	CLIP-seq
MIRT1468799	hsa-miR-532-3p	CLIP-seq
MIRT2140839	hsa-miR-548a-3p	CLIP-seq
MIRT2140840	hsa-miR-548e	CLIP-seq
MIRT2140841	hsa-miR-548f	CLIP-seq
MIRT2140842	hsa-miR-548g	CLIP-seq
MIRT2140843	hsa-miR-548o	CLIP-seq
MIRT2140844	hsa-miR-548p	CLIP-seq
MIRT1468803	hsa-miR-603	CLIP-seq
MIRT2140845	hsa-miR-620	CLIP-seq
MIRT2140846	hsa-miR-625	CLIP-seq
MIRT1468806	hsa-miR-646	CLIP-seq
MIRT1468808	hsa-miR-708	CLIP-seq
MIRT1468809	hsa-miR-761	CLIP-seq
MIRT1468811	hsa-miR-922	CLIP-seq
MIRT2140803	hsa-miR-103a	CLIP-seq
MIRT2140804	hsa-miR-107	CLIP-seq
MIRT2140805	hsa-miR-1206	CLIP-seq
MIRT2361803	hsa-miR-1237	CLIP-seq
MIRT2361804	hsa-miR-1248	CLIP-seq
MIRT2361805	hsa-miR-1252	CLIP-seq
MIRT2361806	hsa-miR-125a-3p	CLIP-seq
MIRT2140806	hsa-miR-1270	CLIP-seq
MIRT2361807	hsa-miR-1275	CLIP-seq
MIRT1468736	hsa-miR-1279	CLIP-seq
MIRT1468738	hsa-miR-1299	CLIP-seq
MIRT2140810	hsa-miR-1323	CLIP-seq
MIRT2361808	hsa-miR-136	CLIP-seq
MIRT1468739	hsa-miR-182	CLIP-seq
MIRT2361809	hsa-miR-185	CLIP-seq
MIRT2361810	hsa-miR-1910	CLIP-seq
MIRT2361811	hsa-miR-196a	CLIP-seq
MIRT2361812	hsa-miR-196b	CLIP-seq
MIRT1468742	hsa-miR-197	CLIP-seq
MIRT2361813	hsa-miR-2052	CLIP-seq
MIRT2361814	hsa-miR-2054	CLIP-seq
MIRT2361815	hsa-miR-2117	CLIP-seq
MIRT2361816	hsa-miR-2392	CLIP-seq
MIRT2361817	hsa-miR-3065-3p	CLIP-seq
MIRT2361818	hsa-miR-30a	CLIP-seq
MIRT2361819	hsa-miR-30b	CLIP-seq
MIRT2361820	hsa-miR-30c	CLIP-seq
MIRT2361821	hsa-miR-30d	CLIP-seq
MIRT2361822	hsa-miR-30e	CLIP-seq
MIRT2361823	hsa-miR-3137	CLIP-seq
MIRT2140815	hsa-miR-3155	CLIP-seq
MIRT2140816	hsa-miR-3155b	CLIP-seq
MIRT2361824	hsa-miR-3185	CLIP-seq
MIRT2361825	hsa-miR-3188	CLIP-seq
MIRT1468752	hsa-miR-3189-5p	CLIP-seq
MIRT2361826	hsa-miR-3192	CLIP-seq
MIRT2361827	hsa-miR-3197	CLIP-seq
MIRT2361828	hsa-miR-3607-3p	CLIP-seq
MIRT2361829	hsa-miR-361-5p	CLIP-seq
MIRT1468755	hsa-miR-3646	CLIP-seq
MIRT2140823	hsa-miR-3649	CLIP-seq
MIRT2361830	hsa-miR-3665	CLIP-seq
MIRT2361831	hsa-miR-3667-5p	CLIP-seq
MIRT2140824	hsa-miR-3671	CLIP-seq
MIRT1468758	hsa-miR-3675-5p	CLIP-seq
MIRT2361832	hsa-miR-3676	CLIP-seq
MIRT2361833	hsa-miR-3686	CLIP-seq
MIRT2361834	hsa-miR-3689a-3p	CLIP-seq
MIRT2361835	hsa-miR-3689c	CLIP-seq
MIRT2140825	hsa-miR-3691-3p	CLIP-seq
MIRT2361836	hsa-miR-3692	CLIP-seq
MIRT2361837	hsa-miR-3920	CLIP-seq
MIRT2361838	hsa-miR-3934	CLIP-seq
MIRT1468763	hsa-miR-3940-5p	CLIP-seq
MIRT2361839	hsa-miR-3942-3p	CLIP-seq
MIRT2361840	hsa-miR-421	CLIP-seq
MIRT2361841	hsa-miR-4260	CLIP-seq
MIRT2140826	hsa-miR-4271	CLIP-seq
MIRT2361842	hsa-miR-4273	CLIP-seq
MIRT1468767	hsa-miR-4283	CLIP-seq
MIRT1468768	hsa-miR-4286	CLIP-seq
MIRT2361843	hsa-miR-4306	CLIP-seq
MIRT2361844	hsa-miR-4314	CLIP-seq
MIRT2361845	hsa-miR-4316	CLIP-seq
MIRT2361846	hsa-miR-4328	CLIP-seq
MIRT1468776	hsa-miR-4468	CLIP-seq
MIRT1468777	hsa-miR-4470	CLIP-seq
MIRT1468778	hsa-miR-4489	CLIP-seq
MIRT1468779	hsa-miR-4495	CLIP-seq
MIRT1468780	hsa-miR-4496	CLIP-seq
MIRT1468781	hsa-miR-4507	CLIP-seq
MIRT2361847	hsa-miR-4509	CLIP-seq
MIRT2361848	hsa-miR-4525	CLIP-seq
MIRT2361849	hsa-miR-455-3p	CLIP-seq
MIRT2361850	hsa-miR-455-5p	CLIP-seq
MIRT2361851	hsa-miR-4643	CLIP-seq
MIRT2361852	hsa-miR-4644	CLIP-seq
MIRT2361853	hsa-miR-4646-5p	CLIP-seq
MIRT2361854	hsa-miR-4651	CLIP-seq
MIRT1468784	hsa-miR-4656	CLIP-seq
MIRT2361855	hsa-miR-4660	CLIP-seq
MIRT2361856	hsa-miR-4665-5p	CLIP-seq
MIRT2361857	hsa-miR-4668-3p	CLIP-seq
MIRT2361858	hsa-miR-4677-3p	CLIP-seq
MIRT2140829	hsa-miR-4683	CLIP-seq
MIRT2361859	hsa-miR-4693-3p	CLIP-seq
MIRT2361860	hsa-miR-4709-3p	CLIP-seq
MIRT2140830	hsa-miR-4709-5p	CLIP-seq
MIRT2361861	hsa-miR-4712-3p	CLIP-seq
MIRT2361862	hsa-miR-4716-5p	CLIP-seq
MIRT2361863	hsa-miR-4723-5p	CLIP-seq
MIRT2140833	hsa-miR-4725-3p	CLIP-seq
MIRT2361864	hsa-miR-4728-5p	CLIP-seq
MIRT1555319	hsa-miR-4731-5p	CLIP-seq
MIRT2361865	hsa-miR-4732-3p	CLIP-seq
MIRT2361866	hsa-miR-4732-5p	CLIP-seq
MIRT2361867	hsa-miR-4755-3p	CLIP-seq
MIRT1468792	hsa-miR-4758-3p	CLIP-seq
MIRT2361868	hsa-miR-4764-5p	CLIP-seq
MIRT2361869	hsa-miR-4768-5p	CLIP-seq
MIRT2361870	hsa-miR-4778-5p	CLIP-seq
MIRT2361871	hsa-miR-4800-3p	CLIP-seq
MIRT2140835	hsa-miR-484	CLIP-seq
MIRT1468794	hsa-miR-488	CLIP-seq
MIRT2361872	hsa-miR-501-3p	CLIP-seq
MIRT2361873	hsa-miR-502-3p	CLIP-seq
MIRT2361874	hsa-miR-502-5p	CLIP-seq
MIRT2361875	hsa-miR-505	CLIP-seq
MIRT2361876	hsa-miR-5096	CLIP-seq
MIRT2361877	hsa-miR-543	CLIP-seq
MIRT2140839	hsa-miR-548a-3p	CLIP-seq
MIRT2361878	hsa-miR-548ac	CLIP-seq
MIRT2361879	hsa-miR-548ae	CLIP-seq
MIRT2361880	hsa-miR-548aj	CLIP-seq
MIRT2361881	hsa-miR-548am	CLIP-seq
MIRT2361882	hsa-miR-548d-3p	CLIP-seq
MIRT2140840	hsa-miR-548e	CLIP-seq
MIRT2140841	hsa-miR-548f	CLIP-seq
MIRT2140842	hsa-miR-548g	CLIP-seq
MIRT1468801	hsa-miR-548m	CLIP-seq
MIRT2140843	hsa-miR-548o	CLIP-seq
MIRT2140844	hsa-miR-548p	CLIP-seq
MIRT2361883	hsa-miR-548x	CLIP-seq
MIRT2361884	hsa-miR-548z	CLIP-seq
MIRT2361885	hsa-miR-570	CLIP-seq
MIRT2361886	hsa-miR-600	CLIP-seq
MIRT1468803	hsa-miR-603	CLIP-seq
MIRT2361887	hsa-miR-608	CLIP-seq
MIRT2140845	hsa-miR-620	CLIP-seq
MIRT2140846	hsa-miR-625	CLIP-seq
MIRT1468806	hsa-miR-646	CLIP-seq
MIRT2361888	hsa-miR-657	CLIP-seq
MIRT2361889	hsa-miR-764	CLIP-seq
MIRT1468810	hsa-miR-875-3p	CLIP-seq
MIRT2361890	hsa-miR-885-5p	CLIP-seq
MIRT2396588	hsa-miR-193a-3p	CLIP-seq
MIRT2396589	hsa-miR-193b	CLIP-seq
MIRT2396590	hsa-miR-1976	CLIP-seq
MIRT2396591	hsa-miR-3064-5p	CLIP-seq
MIRT2361818	hsa-miR-30a	CLIP-seq
MIRT2361819	hsa-miR-30b	CLIP-seq
MIRT2361820	hsa-miR-30c	CLIP-seq
MIRT2361821	hsa-miR-30d	CLIP-seq
MIRT2361822	hsa-miR-30e	CLIP-seq
MIRT2396592	hsa-miR-3202	CLIP-seq
MIRT2361828	hsa-miR-3607-3p	CLIP-seq
MIRT1468767	hsa-miR-4283	CLIP-seq
MIRT1468778	hsa-miR-4489	CLIP-seq
MIRT1468784	hsa-miR-4656	CLIP-seq
MIRT2396593	hsa-miR-4687-3p	CLIP-seq
MIRT1468803	hsa-miR-603	CLIP-seq
MIRT1468806	hsa-miR-646	CLIP-seq
MIRT2396594	hsa-miR-892b	CLIP-seq
MIRT2655642	hsa-miR-125a-5p	CLIP-seq
MIRT2655643	hsa-miR-125b	CLIP-seq
MIRT2655644	hsa-miR-1296	CLIP-seq
MIRT2140809	hsa-miR-1297	CLIP-seq
MIRT1468738	hsa-miR-1299	CLIP-seq
MIRT1468740	hsa-miR-186	CLIP-seq
MIRT2655645	hsa-miR-1912	CLIP-seq
MIRT1468743	hsa-miR-214	CLIP-seq
MIRT2655646	hsa-miR-219-5p	CLIP-seq
MIRT2140813	hsa-miR-26a	CLIP-seq
MIRT2140814	hsa-miR-26b	CLIP-seq
MIRT2655647	hsa-miR-2861	CLIP-seq
MIRT2655648	hsa-miR-3117-5p	CLIP-seq
MIRT2655649	hsa-miR-3130-5p	CLIP-seq
MIRT1468750	hsa-miR-3134	CLIP-seq
MIRT2655650	hsa-miR-3148	CLIP-seq
MIRT2655651	hsa-miR-3154	CLIP-seq
MIRT2655652	hsa-miR-3179	CLIP-seq
MIRT2655653	hsa-miR-3182	CLIP-seq
MIRT1468753	hsa-miR-3591-3p	CLIP-seq
MIRT2655654	hsa-miR-3614-5p	CLIP-seq
MIRT1468754	hsa-miR-3619-5p	CLIP-seq
MIRT1468762	hsa-miR-3936	CLIP-seq
MIRT2361840	hsa-miR-421	CLIP-seq
MIRT1468769	hsa-miR-4291	CLIP-seq
MIRT2655655	hsa-miR-4319	CLIP-seq
MIRT2655656	hsa-miR-4436b-5p	CLIP-seq
MIRT2655657	hsa-miR-4445	CLIP-seq
MIRT1468774	hsa-miR-4446-3p	CLIP-seq
MIRT2140827	hsa-miR-4465	CLIP-seq
MIRT2655658	hsa-miR-4482	CLIP-seq
MIRT2655659	hsa-miR-4512	CLIP-seq
MIRT1468783	hsa-miR-4534	CLIP-seq
MIRT1468784	hsa-miR-4656	CLIP-seq
MIRT2655660	hsa-miR-4668-5p	CLIP-seq
MIRT2140830	hsa-miR-4709-5p	CLIP-seq
MIRT2655661	hsa-miR-4716-3p	CLIP-seq
MIRT1468789	hsa-miR-4722-5p	CLIP-seq
MIRT2361865	hsa-miR-4732-3p	CLIP-seq
MIRT1468793	hsa-miR-4766-5p	CLIP-seq
MIRT2655662	hsa-miR-4782-3p	CLIP-seq
MIRT2655663	hsa-miR-4782-5p	CLIP-seq
MIRT2655664	hsa-miR-4786-5p	CLIP-seq
MIRT1468794	hsa-miR-488	CLIP-seq
MIRT2655665	hsa-miR-508-3p	CLIP-seq
MIRT2655666	hsa-miR-516b	CLIP-seq
MIRT1468796	hsa-miR-520d-5p	CLIP-seq
MIRT1468798	hsa-miR-524-5p	CLIP-seq
MIRT1468801	hsa-miR-548m	CLIP-seq
MIRT2140846	hsa-miR-625	CLIP-seq
MIRT2655667	hsa-miR-670	CLIP-seq
MIRT1468809	hsa-miR-761	CLIP-seq
MIRT2655668	hsa-miR-769-5p	CLIP-seq
MIRT1468810	hsa-miR-875-3p	CLIP-seq
MIRT1468811	hsa-miR-922	CLIP-seq
MIRT1468734	hsa-miR-1257	CLIP-seq
MIRT1468743	hsa-miR-214	CLIP-seq
MIRT1468744	hsa-miR-2355-5p	CLIP-seq
MIRT1468748	hsa-miR-28-5p	CLIP-seq
MIRT1468751	hsa-miR-3139	CLIP-seq
MIRT1468754	hsa-miR-3619-5p	CLIP-seq
MIRT1468759	hsa-miR-3679-3p	CLIP-seq
MIRT1468762	hsa-miR-3936	CLIP-seq
MIRT1468768	hsa-miR-4286	CLIP-seq
MIRT1468769	hsa-miR-4291	CLIP-seq
MIRT1468789	hsa-miR-4722-5p	CLIP-seq
MIRT1468808	hsa-miR-708	CLIP-seq
MIRT1468809	hsa-miR-761	CLIP-seq
MIRT1468811	hsa-miR-922	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000209	Process	Protein polyubiquitination	IBA
GO:0004842	Function	Ubiquitin-protein transferase activity	IDA	20061386
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005524	Function	ATP binding	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IBA
GO:0006513	Process	Protein monoubiquitination	IDA	20061386
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0061631	Function	Ubiquitin conjugating enzyme activity	IBA
GO:0061631	Function	Ubiquitin conjugating enzyme activity	IDA	20061386
GO:0061631	Function	Ubiquitin conjugating enzyme activity	IEA
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	20061386
GO:0070936	Process	Protein K48-linked ubiquitination	IEA

Other IDs

• MIM: 612506
• HGNC: 19907
• e!Ensembl: ENSG00000107341

Protein

• UniProt ID: Q712K3
• Protein name: Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2)
• Protein function: E2 ubiquitin-conjugating enzyme that accepts ubiquitin from an E1 ubiquitin-activating protein, and catalyzes its covalent attachment to other proteins by an E3 ubiquitin-protein ligase complex (PubMed:12037680, PubMed:20061386, PubMed:38326650)
• PDB: 6NYO, 8PQL, 8Q7R, 8R5H
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00179	UQ_con	12 → 169	Ubiquitin-conjugating enzyme	Domain

• Sequence:

  MAQQQMTSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKA
  HIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNV
  RTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSATKAEAEKDG
  VKVPTTLAEYCIKTKVPSNDNSSDLLYDDLYDDDIDDEDEEEEDADCYDDDDSGNEES

• Sequence length: 238

Pathways

KEGG:

Ubiquitin mediated proteolysis

Reactome:

Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
COLORECTAL CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEARING LOSS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Hypospadias	Hypospadias	Pubtator	32728162	Associate	★☆☆☆☆ Found in Text Mining only
Mesothelioma	Mesothelioma	Pubtator	26254420	Associate	★☆☆☆☆ Found in Text Mining only
Mesothelioma Malignant	Mesothelioma	Pubtator	26254420	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	35993308	Associate	★☆☆☆☆ Found in Text Mining only