DCAF16 (DDB1 and CUL4 associated factor 16)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 54876 |
| Gene name | DDB1 and CUL4 associated factor 16 |
| Gene symbol | DCAF16 |
| Synonyms (NCBI Gene) |
C4orf30
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| Chromosome | 4 |
| Chromosome location | 4p15.31 |
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miRNA
miRNA information provided by mirtarbase database.
671
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NXF7 | ||||||||||
| Protein name | DDB1- and CUL4-associated factor 16 | ||||||||||
| Protein function | Functions as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins. | ||||||||||
| PDB | 8G46 , 8OV6 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 216 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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