Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5481
Gene name	Peptidylprolyl isomerase D
Gene symbol	PPID
Synonyms (NCBI Gene)	CYP-40CYPD
Chromosome	4
Chromosome location	4q32.1
Summary	The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has

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miRTarBase ID	miRNA	Experiments	Reference
MIRT028395	hsa-miR-30a-5p	Proteomics	18668040
MIRT032229	hsa-let-7b-5p	Proteomics	18668040
MIRT635610	hsa-miR-496	HITS-CLIP	22927820
MIRT635609	hsa-miR-223-5p	HITS-CLIP	22927820
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	22927820
MIRT706392	hsa-miR-6818-5p	HITS-CLIP	22927820
MIRT706391	hsa-miR-147a	HITS-CLIP	22927820
MIRT706390	hsa-miR-5010-3p	HITS-CLIP	22927820
MIRT635607	hsa-miR-574-5p	HITS-CLIP	22927820
MIRT635610	hsa-miR-496	HITS-CLIP	23313552
MIRT635609	hsa-miR-223-5p	HITS-CLIP	23313552
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT635607	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT635610	hsa-miR-496	HITS-CLIP	23824327
MIRT635609	hsa-miR-223-5p	HITS-CLIP	23824327
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT635607	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT635610	hsa-miR-496	HITS-CLIP	23824327
MIRT635609	hsa-miR-223-5p	HITS-CLIP	23824327
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT635607	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT635610	hsa-miR-496	HITS-CLIP	23824327
MIRT635609	hsa-miR-223-5p	HITS-CLIP	23824327
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT635607	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT706391	hsa-miR-147a	HITS-CLIP	27418678
MIRT635609	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT635609	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT635609	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT635610	hsa-miR-496	HITS-CLIP	27418678
MIRT635610	hsa-miR-496	HITS-CLIP	27418678
MIRT635610	hsa-miR-496	HITS-CLIP	27418678
MIRT706390	hsa-miR-5010-3p	HITS-CLIP	27418678
MIRT635607	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT635607	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT635607	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT706392	hsa-miR-6818-5p	HITS-CLIP	27418678
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT733887	hsa-miR-1203	Luciferase reporter assayWestern blottingqRT-PCR	32041924
MIRT635610	hsa-miR-496	HITS-CLIP	22927820
MIRT635609	hsa-miR-223-5p	HITS-CLIP	22927820
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	22927820
MIRT706392	hsa-miR-6818-5p	HITS-CLIP	22927820
MIRT706391	hsa-miR-147a	HITS-CLIP	22927820
MIRT706390	hsa-miR-5010-3p	HITS-CLIP	22927820
MIRT635607	hsa-miR-574-5p	HITS-CLIP	22927820
MIRT635610	hsa-miR-496	HITS-CLIP	23313552
MIRT635609	hsa-miR-223-5p	HITS-CLIP	23313552
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT635607	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT635610	hsa-miR-496	HITS-CLIP	23824327
MIRT635609	hsa-miR-223-5p	HITS-CLIP	23824327
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT635607	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT635610	hsa-miR-496	HITS-CLIP	23824327
MIRT635609	hsa-miR-223-5p	HITS-CLIP	23824327
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT635607	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT635610	hsa-miR-496	HITS-CLIP	23824327
MIRT635609	hsa-miR-223-5p	HITS-CLIP	23824327
MIRT635608	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT635607	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT756194	hsa-miR-25-3p	Luciferase reporter assayWestern blottingqRT-PCRImmunoprecipitaion (IP)	36276499
MIRT1252875	hsa-miR-1268	CLIP-seq
MIRT1252876	hsa-miR-1268b	CLIP-seq
MIRT1252877	hsa-miR-1273e	CLIP-seq
MIRT1252878	hsa-miR-1827	CLIP-seq
MIRT1252879	hsa-miR-1908	CLIP-seq
MIRT1252880	hsa-miR-2964a-3p	CLIP-seq
MIRT1252881	hsa-miR-302f	CLIP-seq
MIRT1252882	hsa-miR-3122	CLIP-seq
MIRT1252883	hsa-miR-3165	CLIP-seq
MIRT1252884	hsa-miR-3689a-3p	CLIP-seq
MIRT1252885	hsa-miR-3689c	CLIP-seq
MIRT1252886	hsa-miR-3913-5p	CLIP-seq
MIRT1252887	hsa-miR-3974	CLIP-seq
MIRT1252888	hsa-miR-4433	CLIP-seq
MIRT1252889	hsa-miR-4457	CLIP-seq
MIRT1252890	hsa-miR-4459	CLIP-seq
MIRT1252891	hsa-miR-4486	CLIP-seq
MIRT1252892	hsa-miR-4649-3p	CLIP-seq
MIRT1252893	hsa-miR-4651	CLIP-seq
MIRT1252894	hsa-miR-4722-5p	CLIP-seq
MIRT1252895	hsa-miR-4728-5p	CLIP-seq
MIRT1252896	hsa-miR-4747-5p	CLIP-seq
MIRT1252897	hsa-miR-4768-3p	CLIP-seq
MIRT1252898	hsa-miR-508-5p	CLIP-seq
MIRT1252899	hsa-miR-513b	CLIP-seq
MIRT1252900	hsa-miR-550a	CLIP-seq
MIRT1252901	hsa-miR-564	CLIP-seq
MIRT1252902	hsa-miR-585	CLIP-seq
MIRT1252903	hsa-miR-608	CLIP-seq
MIRT1252904	hsa-miR-624	CLIP-seq
MIRT1252905	hsa-miR-661	CLIP-seq
MIRT1252906	hsa-miR-663	CLIP-seq
MIRT1252907	hsa-miR-766	CLIP-seq
MIRT1252908	hsa-miR-890	CLIP-seq
MIRT1252909	hsa-miR-940	CLIP-seq
MIRT2074474	hsa-miR-1228	CLIP-seq
MIRT1252875	hsa-miR-1268	CLIP-seq
MIRT1252876	hsa-miR-1268b	CLIP-seq
MIRT1252878	hsa-miR-1827	CLIP-seq
MIRT2074475	hsa-miR-24	CLIP-seq
MIRT1252880	hsa-miR-2964a-3p	CLIP-seq
MIRT1252881	hsa-miR-302f	CLIP-seq
MIRT2074476	hsa-miR-342-3p	CLIP-seq
MIRT2074477	hsa-miR-371-5p	CLIP-seq
MIRT2074478	hsa-miR-371b-5p	CLIP-seq
MIRT2074479	hsa-miR-4284	CLIP-seq
MIRT2074480	hsa-miR-4432	CLIP-seq
MIRT1252891	hsa-miR-4486	CLIP-seq
MIRT1252892	hsa-miR-4649-3p	CLIP-seq
MIRT1252894	hsa-miR-4722-5p	CLIP-seq
MIRT2074481	hsa-miR-4743	CLIP-seq
MIRT1252896	hsa-miR-4747-5p	CLIP-seq
MIRT1252897	hsa-miR-4768-3p	CLIP-seq
MIRT2074482	hsa-miR-495	CLIP-seq
MIRT2074483	hsa-miR-548c-3p	CLIP-seq
MIRT1252900	hsa-miR-550a	CLIP-seq
MIRT1252901	hsa-miR-564	CLIP-seq
MIRT1252902	hsa-miR-585	CLIP-seq
MIRT1252908	hsa-miR-890	CLIP-seq
MIRT1252909	hsa-miR-940	CLIP-seq
MIRT2074474	hsa-miR-1228	CLIP-seq
MIRT2301470	hsa-miR-1262	CLIP-seq
MIRT1252877	hsa-miR-1273e	CLIP-seq
MIRT1252878	hsa-miR-1827	CLIP-seq
MIRT2074475	hsa-miR-24	CLIP-seq
MIRT2301471	hsa-miR-2467-3p	CLIP-seq
MIRT1252880	hsa-miR-2964a-3p	CLIP-seq
MIRT1252881	hsa-miR-302f	CLIP-seq
MIRT2074476	hsa-miR-342-3p	CLIP-seq
MIRT2301472	hsa-miR-3605-5p	CLIP-seq
MIRT2301473	hsa-miR-3612	CLIP-seq
MIRT2074479	hsa-miR-4284	CLIP-seq
MIRT2074480	hsa-miR-4432	CLIP-seq
MIRT2301474	hsa-miR-451b	CLIP-seq
MIRT2301475	hsa-miR-4537	CLIP-seq
MIRT1252892	hsa-miR-4649-3p	CLIP-seq
MIRT2301476	hsa-miR-4696	CLIP-seq
MIRT2301477	hsa-miR-4701-3p	CLIP-seq
MIRT1252894	hsa-miR-4722-5p	CLIP-seq
MIRT2074481	hsa-miR-4743	CLIP-seq
MIRT1252896	hsa-miR-4747-5p	CLIP-seq
MIRT1252897	hsa-miR-4768-3p	CLIP-seq
MIRT1252898	hsa-miR-508-5p	CLIP-seq
MIRT2301478	hsa-miR-542-3p	CLIP-seq
MIRT1252900	hsa-miR-550a	CLIP-seq
MIRT1252901	hsa-miR-564	CLIP-seq
MIRT2301479	hsa-miR-650	CLIP-seq
MIRT1252905	hsa-miR-661	CLIP-seq
MIRT1252907	hsa-miR-766	CLIP-seq
MIRT1252908	hsa-miR-890	CLIP-seq
MIRT1252909	hsa-miR-940	CLIP-seq
MIRT1252901	hsa-miR-564	CLIP-seq
MIRT1252908	hsa-miR-890	CLIP-seq
MIRT1252901	hsa-miR-564	CLIP-seq
MIRT1252901	hsa-miR-564	CLIP-seq
MIRT2074474	hsa-miR-1228	CLIP-seq
MIRT2301470	hsa-miR-1262	CLIP-seq
MIRT1252875	hsa-miR-1268	CLIP-seq
MIRT1252876	hsa-miR-1268b	CLIP-seq
MIRT1252877	hsa-miR-1273e	CLIP-seq
MIRT1252878	hsa-miR-1827	CLIP-seq
MIRT1252879	hsa-miR-1908	CLIP-seq
MIRT1252880	hsa-miR-2964a-3p	CLIP-seq
MIRT1252881	hsa-miR-302f	CLIP-seq
MIRT1252882	hsa-miR-3122	CLIP-seq
MIRT1252883	hsa-miR-3165	CLIP-seq
MIRT2598191	hsa-miR-3675-3p	CLIP-seq
MIRT1252884	hsa-miR-3689a-3p	CLIP-seq
MIRT1252885	hsa-miR-3689c	CLIP-seq
MIRT2074477	hsa-miR-371-5p	CLIP-seq
MIRT2074478	hsa-miR-371b-5p	CLIP-seq
MIRT1252886	hsa-miR-3913-5p	CLIP-seq
MIRT1252887	hsa-miR-3974	CLIP-seq
MIRT2074480	hsa-miR-4432	CLIP-seq
MIRT1252888	hsa-miR-4433	CLIP-seq
MIRT1252889	hsa-miR-4457	CLIP-seq
MIRT1252890	hsa-miR-4459	CLIP-seq
MIRT1252891	hsa-miR-4486	CLIP-seq
MIRT2301474	hsa-miR-451b	CLIP-seq
MIRT1252892	hsa-miR-4649-3p	CLIP-seq
MIRT1252893	hsa-miR-4651	CLIP-seq
MIRT2598192	hsa-miR-4684-5p	CLIP-seq
MIRT2301476	hsa-miR-4696	CLIP-seq
MIRT2301477	hsa-miR-4701-3p	CLIP-seq
MIRT1252894	hsa-miR-4722-5p	CLIP-seq
MIRT1252895	hsa-miR-4728-5p	CLIP-seq
MIRT1252896	hsa-miR-4747-5p	CLIP-seq
MIRT1252897	hsa-miR-4768-3p	CLIP-seq
MIRT2074482	hsa-miR-495	CLIP-seq
MIRT1252898	hsa-miR-508-5p	CLIP-seq
MIRT1252899	hsa-miR-513b	CLIP-seq
MIRT2301478	hsa-miR-542-3p	CLIP-seq
MIRT2598193	hsa-miR-548aa	CLIP-seq
MIRT2074483	hsa-miR-548c-3p	CLIP-seq
MIRT1252900	hsa-miR-550a	CLIP-seq
MIRT1252901	hsa-miR-564	CLIP-seq
MIRT1252902	hsa-miR-585	CLIP-seq
MIRT1252903	hsa-miR-608	CLIP-seq
MIRT1252904	hsa-miR-624	CLIP-seq
MIRT1252905	hsa-miR-661	CLIP-seq
MIRT1252906	hsa-miR-663	CLIP-seq
MIRT1252907	hsa-miR-766	CLIP-seq
MIRT1252908	hsa-miR-890	CLIP-seq
MIRT1252909	hsa-miR-940	CLIP-seq
MIRT2074474	hsa-miR-1228	CLIP-seq
MIRT2301470	hsa-miR-1262	CLIP-seq
MIRT1252875	hsa-miR-1268	CLIP-seq
MIRT1252876	hsa-miR-1268b	CLIP-seq
MIRT1252877	hsa-miR-1273e	CLIP-seq
MIRT1252878	hsa-miR-1827	CLIP-seq
MIRT1252879	hsa-miR-1908	CLIP-seq
MIRT1252880	hsa-miR-2964a-3p	CLIP-seq
MIRT1252881	hsa-miR-302f	CLIP-seq
MIRT1252882	hsa-miR-3122	CLIP-seq
MIRT1252883	hsa-miR-3165	CLIP-seq
MIRT2598191	hsa-miR-3675-3p	CLIP-seq
MIRT1252884	hsa-miR-3689a-3p	CLIP-seq
MIRT1252885	hsa-miR-3689c	CLIP-seq
MIRT2074477	hsa-miR-371-5p	CLIP-seq
MIRT2074478	hsa-miR-371b-5p	CLIP-seq
MIRT1252886	hsa-miR-3913-5p	CLIP-seq
MIRT1252887	hsa-miR-3974	CLIP-seq
MIRT2074480	hsa-miR-4432	CLIP-seq
MIRT1252888	hsa-miR-4433	CLIP-seq
MIRT1252889	hsa-miR-4457	CLIP-seq
MIRT1252890	hsa-miR-4459	CLIP-seq
MIRT1252891	hsa-miR-4486	CLIP-seq
MIRT2301474	hsa-miR-451b	CLIP-seq
MIRT1252892	hsa-miR-4649-3p	CLIP-seq
MIRT1252893	hsa-miR-4651	CLIP-seq
MIRT2598192	hsa-miR-4684-5p	CLIP-seq
MIRT2301476	hsa-miR-4696	CLIP-seq
MIRT2301477	hsa-miR-4701-3p	CLIP-seq
MIRT1252894	hsa-miR-4722-5p	CLIP-seq
MIRT1252895	hsa-miR-4728-5p	CLIP-seq
MIRT1252896	hsa-miR-4747-5p	CLIP-seq
MIRT1252897	hsa-miR-4768-3p	CLIP-seq
MIRT2074482	hsa-miR-495	CLIP-seq
MIRT1252898	hsa-miR-508-5p	CLIP-seq
MIRT1252899	hsa-miR-513b	CLIP-seq
MIRT2301478	hsa-miR-542-3p	CLIP-seq
MIRT2598193	hsa-miR-548aa	CLIP-seq
MIRT2074483	hsa-miR-548c-3p	CLIP-seq
MIRT1252900	hsa-miR-550a	CLIP-seq
MIRT1252901	hsa-miR-564	CLIP-seq
MIRT1252902	hsa-miR-585	CLIP-seq
MIRT1252903	hsa-miR-608	CLIP-seq
MIRT1252904	hsa-miR-624	CLIP-seq
MIRT1252905	hsa-miR-661	CLIP-seq
MIRT1252906	hsa-miR-663	CLIP-seq
MIRT1252907	hsa-miR-766	CLIP-seq
MIRT1252908	hsa-miR-890	CLIP-seq
MIRT1252909	hsa-miR-940	CLIP-seq

Show/Hide all (39)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IMP	18708059
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IBA
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IDA	11350175, 20676357
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IEA
GO:0005515	Function	Protein binding	IPI	9659917, 16507998, 18806802, 21146485, 28514442, 30266287, 33961781
GO:0005634	Component	Nucleus	IDA	11525244
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA	11525244
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	11525244
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0005929	Component	Cilium	IDA
GO:0006457	Process	Protein folding	IBA
GO:0006457	Process	Protein folding	IDA	11350175
GO:0006457	Process	Protein folding	IEA
GO:0006457	Process	Protein folding	ISS
GO:0006915	Process	Apoptotic process	IEA
GO:0008134	Function	Transcription factor binding	IDA	9659917
GO:0015031	Process	Protein transport	IEA
GO:0016018	Function	Cyclosporin A binding	IBA
GO:0016018	Function	Cyclosporin A binding	TAS	7744028, 8812478
GO:0016853	Function	Isomerase activity	IEA
GO:0019076	Process	Viral release from host cell	TAS	21711559
GO:0030331	Function	Nuclear estrogen receptor binding	ISS
GO:0030544	Function	Hsp70 protein binding	ISS
GO:0031072	Function	Heat shock protein binding	IPI	9660753
GO:0034389	Process	Lipid droplet organization	IMP	21711559
GO:0043065	Process	Positive regulation of apoptotic process	IMP	23220213
GO:0045070	Process	Positive regulation of viral genome replication	IMP	19932913
GO:0050714	Process	Positive regulation of protein secretion	IMP	21711559
GO:0051879	Function	Hsp90 protein binding	IDA	12145316
GO:0065003	Process	Protein-containing complex assembly	IDA	18708059
GO:0071492	Process	Cellular response to UV-A	IMP	23220213

MIM	HGNC	e!Ensembl
601753	9257	ENSG00000171497

Q08752

Protein name

Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (40 kDa peptidyl-prolyl cis-trans isomerase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein) (Rotamase D)

Protein function

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:11350175, PubMed:20676357). Proposed to act as a co-chaperone in HSP90 complexes such as in unlig

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00160	Pro_isomerase	19 → 183	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Domain
PF13176	TPR_7	226 → 258	Tetratricopeptide repeat	Repeat

Tissue specificity

TISSUE SPECIFICITY: Widely expressed.

Sequence

MSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGH
TTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSM
ANAGRNTNGSQFFITTVPTPHLDGKHVVFGQVIKGIGVARILENVEVKGEKPAKLCVIAE
CGELKEGDDGGIFPKDGSGDSHPDFPEDADIDLKDVDKILLITEDLKNIGNTFFKSQNWE
MAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLKMSNWQGAIDSCLEAL
ELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQAELLKVKQKIKAQKDK
EKAVYAKMFA

Sequence length

370

Interactions

View interactions

	KEGG		Reactome
	Necroptosis Cellular senescence Alzheimer disease Pathways of neurodegeneration - multiple diseases Shigellosis		ESR-mediated signaling

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (59)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute pancreatitis	Pancreatitis	BEFREE	29074451, 31631343		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adrenoleukodystrophy	Adrenoleukodystrophy	BEFREE	23492556		★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyloidosis	Amyloidosis	BEFREE	28913661		★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	23486940		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	PSYGENET_DG	20392297		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Brain Injuries	Brain injuries	Pubtator	21121808	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	11216911, 11374893, 23598413, 30662615		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	11216911, 23598413	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	BEFREE	31566215		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	BEFREE	23538482		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cockayne Syndrome, Type I	Cockayne Syndrome	BEFREE	28273124		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	29374515		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	15004035	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	31464387		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	28378042		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	20479245, 25096625, 31039005		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	20479245, 25096625, 31039005		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty Liver	BEFREE	29356058, 29603199		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glaucoma, Primary Open Angle	Glaucoma	BEFREE	18614807		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	28684269		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	28684269		★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Diseases	Heart disease	Pubtator	38412332	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	BEFREE	31464387		★★★★★ ★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington disease	Pubtator	21257639	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	BEFREE	25096625		★★★★★ ★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	25096625, 28236057		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	BEFREE	28428752, 31800959		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Failure, Acute	Kidney Failure	BEFREE	29230844, 31339772, 31733829		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	22681779		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	30662615		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	24732633		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	20023700		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	11216911, 26973251, 28492973		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	29374515		★★★★★ ★☆☆☆☆ Found in Text Mining only
Memory dysfunction	Memory Disorders	BEFREE	28236057		★★★★★ ★☆☆☆☆ Found in Text Mining only
Meningioma	Meningioma	Pubtator	24603329	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Meningioma	Meningioma	BEFREE	29302888		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	31464387		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Mitochondrial disease	Pubtator	23108666, 31089403	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mitochondrial Myopathies	Mitochondrial myopathy	BEFREE	26374844		★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy	Muscular dystrophy	BEFREE	18345011		★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy, Duchenne	Duchenne Muscular Dystrophy	BEFREE	23804750		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	28378042		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial Ischemia	BEFREE	28378042		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	11216911, 23376257		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	21121808	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	23492556		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	31464387		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	24732633		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatitis	Pancreatitis	BEFREE	29074451, 31631343		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatitis	Pancreatitis	Pubtator	38050301	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	21529244, 30297105		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	20023700		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	17615153	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	20023700	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal fibrosis	Renal fibrosis	BEFREE	29230844		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	38412332	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sleep Apnea, Central	Sleep Apnea	BEFREE	28273124		★★★★★ ★☆☆☆☆ Found in Text Mining only
Steatohepatitis	Fatty Liver	BEFREE	29356058		★★★★★ ★☆☆☆☆ Found in Text Mining only

PPID (peptidylprolyl isomerase D)