Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5453
Gene name	POU class 3 homeobox 1
Gene symbol	POU3F1
Synonyms (NCBI Gene)	OCT6OTF6SCIP
Chromosome	1
Chromosome location	1p34.3

300

Show/Hide all (300)

miRTarBase ID	miRNA	Experiments	Reference
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT627842	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT627841	hsa-miR-146a-5p	HITS-CLIP	23824327
MIRT627840	hsa-miR-146b-5p	HITS-CLIP	23824327
MIRT627839	hsa-miR-7153-5p	HITS-CLIP	23824327
MIRT627838	hsa-miR-4434	HITS-CLIP	23824327
MIRT627837	hsa-miR-4516	HITS-CLIP	23824327
MIRT627836	hsa-miR-5703	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT627835	hsa-miR-4531	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	PAR-CLIP	23592263
MIRT488112	hsa-miR-4787-5p	PAR-CLIP	23592263
MIRT488111	hsa-miR-1909-3p	PAR-CLIP	23592263
MIRT488110	hsa-miR-6722-3p	PAR-CLIP	23592263
MIRT488109	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT488108	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT488107	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT488106	hsa-miR-663a	PAR-CLIP	23592263
MIRT488104	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT488105	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT488103	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT488102	hsa-miR-3180	PAR-CLIP	23592263
MIRT488101	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT488100	hsa-miR-3196	PAR-CLIP	23592263
MIRT488099	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT488098	hsa-miR-328-5p	PAR-CLIP	23592263
MIRT488097	hsa-miR-6885-5p	PAR-CLIP	23592263
MIRT488096	hsa-miR-7704	PAR-CLIP	23592263
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT627842	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT627841	hsa-miR-146a-5p	HITS-CLIP	23824327
MIRT627840	hsa-miR-146b-5p	HITS-CLIP	23824327
MIRT627839	hsa-miR-7153-5p	HITS-CLIP	23824327
MIRT627838	hsa-miR-4434	HITS-CLIP	23824327
MIRT627837	hsa-miR-4516	HITS-CLIP	23824327
MIRT627836	hsa-miR-5703	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT627835	hsa-miR-4531	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT613920	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	HITS-CLIP	23824327
MIRT613919	hsa-miR-3183	HITS-CLIP	23824327
MIRT613918	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT613917	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT613915	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT613916	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT613914	hsa-miR-3909	HITS-CLIP	23824327
MIRT613913	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT613912	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT613911	hsa-miR-4279	HITS-CLIP	23824327
MIRT488113	hsa-miR-4532	PAR-CLIP	23592263
MIRT488112	hsa-miR-4787-5p	PAR-CLIP	23592263
MIRT488111	hsa-miR-1909-3p	PAR-CLIP	23592263
MIRT488110	hsa-miR-6722-3p	PAR-CLIP	23592263
MIRT488109	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT488108	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT488107	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT488106	hsa-miR-663a	PAR-CLIP	23592263
MIRT488104	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT488105	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT488103	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT488102	hsa-miR-3180	PAR-CLIP	23592263
MIRT488101	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT488100	hsa-miR-3196	PAR-CLIP	23592263
MIRT488099	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT488098	hsa-miR-328-5p	PAR-CLIP	23592263
MIRT488097	hsa-miR-6885-5p	PAR-CLIP	23592263
MIRT488096	hsa-miR-7704	PAR-CLIP	23592263
MIRT1250948	hsa-miR-1275	CLIP-seq
MIRT1250949	hsa-miR-2278	CLIP-seq
MIRT1250950	hsa-miR-24	CLIP-seq
MIRT1250951	hsa-miR-3151	CLIP-seq
MIRT1250952	hsa-miR-3153	CLIP-seq
MIRT1250953	hsa-miR-3155	CLIP-seq
MIRT1250954	hsa-miR-3155b	CLIP-seq
MIRT1250955	hsa-miR-3620	CLIP-seq
MIRT1250956	hsa-miR-3646	CLIP-seq
MIRT1250957	hsa-miR-3662	CLIP-seq
MIRT1250958	hsa-miR-3690	CLIP-seq
MIRT1250959	hsa-miR-3937	CLIP-seq
MIRT1250960	hsa-miR-3960	CLIP-seq
MIRT1250961	hsa-miR-4260	CLIP-seq
MIRT1250962	hsa-miR-4308	CLIP-seq
MIRT1250963	hsa-miR-4467	CLIP-seq
MIRT1250964	hsa-miR-4651	CLIP-seq
MIRT1250965	hsa-miR-4665-5p	CLIP-seq
MIRT1250966	hsa-miR-4690-5p	CLIP-seq
MIRT1250967	hsa-miR-4723-5p	CLIP-seq
MIRT1250968	hsa-miR-4728-5p	CLIP-seq
MIRT1250969	hsa-miR-4781-5p	CLIP-seq
MIRT1250970	hsa-miR-484	CLIP-seq
MIRT1250971	hsa-miR-608	CLIP-seq
MIRT1250972	hsa-miR-711	CLIP-seq
MIRT2074085	hsa-miR-1184	CLIP-seq
MIRT1250950	hsa-miR-24	CLIP-seq
MIRT2074086	hsa-miR-298	CLIP-seq
MIRT1250953	hsa-miR-3155	CLIP-seq
MIRT1250954	hsa-miR-3155b	CLIP-seq
MIRT1250955	hsa-miR-3620	CLIP-seq
MIRT1250956	hsa-miR-3646	CLIP-seq
MIRT1250957	hsa-miR-3662	CLIP-seq
MIRT1250958	hsa-miR-3690	CLIP-seq
MIRT1250962	hsa-miR-4308	CLIP-seq
MIRT2074087	hsa-miR-4436b-3p	CLIP-seq
MIRT1250970	hsa-miR-484	CLIP-seq
MIRT1250972	hsa-miR-711	CLIP-seq
MIRT2301069	hsa-miR-103a	CLIP-seq
MIRT2301070	hsa-miR-107	CLIP-seq
MIRT2074085	hsa-miR-1184	CLIP-seq
MIRT2301071	hsa-miR-1205	CLIP-seq
MIRT2301072	hsa-miR-214	CLIP-seq
MIRT1250950	hsa-miR-24	CLIP-seq
MIRT2301073	hsa-miR-3074-5p	CLIP-seq
MIRT1250953	hsa-miR-3155	CLIP-seq
MIRT1250954	hsa-miR-3155b	CLIP-seq
MIRT2301074	hsa-miR-3158-5p	CLIP-seq
MIRT2301075	hsa-miR-3619-5p	CLIP-seq
MIRT1250955	hsa-miR-3620	CLIP-seq
MIRT1250958	hsa-miR-3690	CLIP-seq
MIRT2301076	hsa-miR-370	CLIP-seq
MIRT1250962	hsa-miR-4308	CLIP-seq
MIRT2074087	hsa-miR-4436b-3p	CLIP-seq
MIRT2301077	hsa-miR-4527	CLIP-seq
MIRT2301078	hsa-miR-4672	CLIP-seq
MIRT2301079	hsa-miR-4789-5p	CLIP-seq
MIRT1250970	hsa-miR-484	CLIP-seq
MIRT1250972	hsa-miR-711	CLIP-seq
MIRT2301080	hsa-miR-761	CLIP-seq
MIRT2392861	hsa-miR-324-5p	CLIP-seq
MIRT2456938	hsa-miR-1538	CLIP-seq
MIRT2456939	hsa-miR-1908	CLIP-seq
MIRT2456940	hsa-miR-3195	CLIP-seq
MIRT2456941	hsa-miR-4745-3p	CLIP-seq
MIRT2456942	hsa-miR-663	CLIP-seq
MIRT2465873	hsa-miR-2467-3p	CLIP-seq
MIRT2465874	hsa-miR-3652	CLIP-seq
MIRT2465875	hsa-miR-3978	CLIP-seq
MIRT2465876	hsa-miR-4430	CLIP-seq
MIRT2465877	hsa-miR-4468	CLIP-seq
MIRT2465878	hsa-miR-875-3p	CLIP-seq

Show/Hide all (30)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0003700	Function	DNA-binding transcription factor activity	TAS	8451175, 8662541
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005667	Component	Transcription regulator complex	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0007420	Process	Brain development	IEA
GO:0008366	Process	Axon ensheathment	TAS	8662541
GO:0008544	Process	Epidermis development	IEA
GO:0010628	Process	Positive regulation of gene expression	IEA
GO:0010628	Process	Positive regulation of gene expression	ISS
GO:0014044	Process	Schwann cell development	IEA
GO:0022011	Process	Myelination in peripheral nervous system	IEA
GO:0030216	Process	Keratinocyte differentiation	IEA
GO:0030900	Process	Forebrain development	IEA
GO:0042552	Process	Myelination	IEA
GO:0043565	Function	Sequence-specific DNA binding	IDA	9242494
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
602479	9214	ENSG00000185668

Q03052

Protein name

POU domain, class 3, transcription factor 1 (Octamer-binding protein 6) (Oct-6) (Octamer-binding transcription factor 6) (OTF-6) (POU domain transcription factor SCIP)

Protein function

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') (By similarity). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity). Acts as a transcriptional repress

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00157	Pou	250 → 321	Pou domain - N-terminal to homeobox domain	Domain
PF00046	Homeodomain	340 → 396	Homeodomain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in embryonal stem cells and in the developing brain.

Sequence

MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGA
GAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQG
AAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGG
GGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSS
VGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ
LSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLK
CPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG
GGGASPPSAPPPPPPAALHHHHHHTLPGSVQ

Sequence length

451

Interactions

View interactions

	Reactome
			EGR2 and SOX10-mediated initiation of Schwann cell myelination

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ARTHRITIS, RHEUMATOID	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (23)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adult Oligodendroglioma	Oligodendroglioma	BEFREE	8875464		★★★★★ ★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	Pubtator	15367334	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	BEFREE	16246257		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	25772757		★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood Oligodendroglioma	Oligodendroglioma	BEFREE	8875464		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	28642028		★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	12384147		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	21448695		★★★★★ ★☆☆☆☆ Found in Text Mining only
Major Depressive Disorder	Mental Depression	BEFREE	16246257		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	25772757		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental disorders	Mental Disorders	BEFREE	16246257		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mood Disorders	Mood Disorder	BEFREE	28280345		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	21448695		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neural Tube Defects	Neural Tube Defect	BEFREE	28434941		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	31212703		★★★★★ ★☆☆☆☆ Found in Text Mining only
oligodendroglioma	Oligodendroglioma	BEFREE	8875464		★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral Neuropathy	Peripheral Neuropathy	LHGDN	17959798		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	CTD_human_DG	23143596		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	BEFREE	15006499		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	16246257	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	35619584	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Unipolar Depression	Mental Depression	BEFREE	16246257		★★★★★ ★☆☆☆☆ Found in Text Mining only
Well Differentiated Oligodendroglioma	Oligodendroglioma	BEFREE	8875464		★★★★★ ★☆☆☆☆ Found in Text Mining only

POU3F1 (POU class 3 homeobox 1)