Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5452
Gene name	POU class 2 homeobox 2
Gene symbol	POU2F2
Synonyms (NCBI Gene)	OCT2OTF2Oct-2
Chromosome	19
Chromosome location	19q13.2
Summary	The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5`-ATTTGCAT-3`, a common transcription factor binding site in immunoglobulin gene promoters. Several tr

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Show/Hide all (239)

miRTarBase ID	miRNA	Experiments	Reference
MIRT000639	hsa-miR-9-5p	Luciferase reporter assay	19956200
MIRT720159	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT720158	hsa-miR-4753-3p	HITS-CLIP	19536157
MIRT720157	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT388051	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT388056	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT388055	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT720156	hsa-miR-659-3p	HITS-CLIP	19536157
MIRT720155	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT521796	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT509447	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509446	hsa-miR-4307	HITS-CLIP	21572407
MIRT509445	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509444	hsa-miR-6083	HITS-CLIP	21572407
MIRT509443	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT509447	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509446	hsa-miR-4307	HITS-CLIP	21572407
MIRT509445	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509444	hsa-miR-6083	HITS-CLIP	21572407
MIRT509443	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT614841	hsa-miR-6768-3p	HITS-CLIP	23824327
MIRT614840	hsa-miR-6512-5p	HITS-CLIP	23824327
MIRT614839	hsa-miR-6841-5p	HITS-CLIP	23824327
MIRT614838	hsa-miR-6755-5p	HITS-CLIP	23824327
MIRT666873	hsa-miR-504-5p	HITS-CLIP	23824327
MIRT666872	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT666871	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT666870	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT666869	hsa-miR-4639-3p	HITS-CLIP	23824327
MIRT666868	hsa-miR-3162-3p	HITS-CLIP	23824327
MIRT666867	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT666866	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT666865	hsa-miR-6794-3p	HITS-CLIP	23824327
MIRT666864	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT614841	hsa-miR-6768-3p	HITS-CLIP	23824327
MIRT614840	hsa-miR-6512-5p	HITS-CLIP	23824327
MIRT614839	hsa-miR-6841-5p	HITS-CLIP	23824327
MIRT614838	hsa-miR-6755-5p	HITS-CLIP	23824327
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT509446	hsa-miR-4307	PAR-CLIP	20371350
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT509444	hsa-miR-6083	PAR-CLIP	20371350
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT521799	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT521798	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT521797	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT521796	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509446	hsa-miR-4307	PAR-CLIP	21572407
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509444	hsa-miR-6083	PAR-CLIP	21572407
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT521799	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT521798	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT521797	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT521796	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509446	hsa-miR-4307	PAR-CLIP	21572407
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509444	hsa-miR-6083	PAR-CLIP	21572407
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT521799	hsa-miR-3606-3p	PAR-CLIP	23446348
MIRT521798	hsa-miR-513a-3p	PAR-CLIP	23446348
MIRT521797	hsa-miR-513c-3p	PAR-CLIP	23446348
MIRT521796	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509446	hsa-miR-4307	PAR-CLIP	23446348
MIRT521795	hsa-miR-6832-3p	PAR-CLIP	23446348
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT521794	hsa-miR-623	PAR-CLIP	23446348
MIRT521793	hsa-miR-204-5p	PAR-CLIP	23446348
MIRT521792	hsa-miR-211-5p	PAR-CLIP	23446348
MIRT509444	hsa-miR-6083	PAR-CLIP	23446348
MIRT521791	hsa-miR-4755-5p	PAR-CLIP	23446348
MIRT521790	hsa-miR-5006-3p	PAR-CLIP	23446348
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509446	hsa-miR-4307	PAR-CLIP	23446348
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509444	hsa-miR-6083	PAR-CLIP	23446348
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT731733	hsa-miR-218-5p	ChIP-seqImmunofluorescenceImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	26019213
MIRT731733	hsa-miR-218-5p	ChIP-seqImmunofluorescenceImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	26019213
MIRT720156	hsa-miR-659-3p	HITS-CLIP	27418678
MIRT736663	hsa-miR-489-3p	Luciferase reporter assayWestern blottingImmunoprecipitaion (IP)qRT-PCR	31649850
MIRT736664	hsa-miR-630	Luciferase reporter assayWestern blottingImmunoprecipitaion (IP)qRT-PCR	31649850
MIRT720159	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT720158	hsa-miR-4753-3p	HITS-CLIP	19536157
MIRT720157	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT388051	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT388056	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT388055	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT720156	hsa-miR-659-3p	HITS-CLIP	19536157
MIRT720155	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT521796	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT509447	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509446	hsa-miR-4307	HITS-CLIP	21572407
MIRT509445	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509444	hsa-miR-6083	HITS-CLIP	21572407
MIRT509443	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT509447	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509446	hsa-miR-4307	HITS-CLIP	21572407
MIRT509445	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509444	hsa-miR-6083	HITS-CLIP	21572407
MIRT509443	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT614841	hsa-miR-6768-3p	HITS-CLIP	23824327
MIRT614840	hsa-miR-6512-5p	HITS-CLIP	23824327
MIRT614839	hsa-miR-6841-5p	HITS-CLIP	23824327
MIRT614838	hsa-miR-6755-5p	HITS-CLIP	23824327
MIRT666873	hsa-miR-504-5p	HITS-CLIP	23824327
MIRT666872	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT666871	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT666870	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT666869	hsa-miR-4639-3p	HITS-CLIP	23824327
MIRT666868	hsa-miR-3162-3p	HITS-CLIP	23824327
MIRT666867	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT666866	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT666865	hsa-miR-6794-3p	HITS-CLIP	23824327
MIRT666864	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT614841	hsa-miR-6768-3p	HITS-CLIP	23824327
MIRT614840	hsa-miR-6512-5p	HITS-CLIP	23824327
MIRT614839	hsa-miR-6841-5p	HITS-CLIP	23824327
MIRT614838	hsa-miR-6755-5p	HITS-CLIP	23824327
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT509446	hsa-miR-4307	PAR-CLIP	20371350
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT509444	hsa-miR-6083	PAR-CLIP	20371350
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT521799	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT521798	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT521797	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT521796	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509446	hsa-miR-4307	PAR-CLIP	21572407
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509444	hsa-miR-6083	PAR-CLIP	21572407
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT521799	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT521798	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT521797	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT521796	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509446	hsa-miR-4307	PAR-CLIP	21572407
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509444	hsa-miR-6083	PAR-CLIP	21572407
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT521799	hsa-miR-3606-3p	PAR-CLIP	23446348
MIRT521798	hsa-miR-513a-3p	PAR-CLIP	23446348
MIRT521797	hsa-miR-513c-3p	PAR-CLIP	23446348
MIRT521796	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509446	hsa-miR-4307	PAR-CLIP	23446348
MIRT521795	hsa-miR-6832-3p	PAR-CLIP	23446348
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT521794	hsa-miR-623	PAR-CLIP	23446348
MIRT521793	hsa-miR-204-5p	PAR-CLIP	23446348
MIRT521792	hsa-miR-211-5p	PAR-CLIP	23446348
MIRT509444	hsa-miR-6083	PAR-CLIP	23446348
MIRT521791	hsa-miR-4755-5p	PAR-CLIP	23446348
MIRT521790	hsa-miR-5006-3p	PAR-CLIP	23446348
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509447	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509446	hsa-miR-4307	PAR-CLIP	23446348
MIRT509445	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509444	hsa-miR-6083	PAR-CLIP	23446348
MIRT509443	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT1250900	hsa-miR-3127-5p	CLIP-seq
MIRT1250901	hsa-miR-4261	CLIP-seq
MIRT1250902	hsa-miR-4270	CLIP-seq
MIRT1250903	hsa-miR-4441	CLIP-seq
MIRT1250904	hsa-miR-659	CLIP-seq
MIRT1250905	hsa-miR-1237	CLIP-seq
MIRT1250906	hsa-miR-1238	CLIP-seq
MIRT1250907	hsa-miR-1248	CLIP-seq
MIRT1250908	hsa-miR-1976	CLIP-seq
MIRT1250909	hsa-miR-223	CLIP-seq
MIRT1250910	hsa-miR-3150a-3p	CLIP-seq
MIRT1250911	hsa-miR-3175	CLIP-seq
MIRT1250912	hsa-miR-3180-5p	CLIP-seq
MIRT1250913	hsa-miR-320e	CLIP-seq
MIRT1250914	hsa-miR-370	CLIP-seq
MIRT1250915	hsa-miR-4277	CLIP-seq
MIRT1250916	hsa-miR-4287	CLIP-seq
MIRT1250917	hsa-miR-4419a	CLIP-seq
MIRT1250918	hsa-miR-4505	CLIP-seq
MIRT1250919	hsa-miR-4510	CLIP-seq
MIRT1250920	hsa-miR-4642	CLIP-seq
MIRT1250921	hsa-miR-4667-5p	CLIP-seq
MIRT1250922	hsa-miR-4685-3p	CLIP-seq
MIRT1250923	hsa-miR-4691-5p	CLIP-seq
MIRT1250924	hsa-miR-4700-5p	CLIP-seq
MIRT1250925	hsa-miR-4720-5p	CLIP-seq
MIRT1250926	hsa-miR-4728-5p	CLIP-seq
MIRT1250927	hsa-miR-4731-5p	CLIP-seq
MIRT1250928	hsa-miR-4780	CLIP-seq
MIRT1250929	hsa-miR-4799-3p	CLIP-seq
MIRT1250930	hsa-miR-483-3p	CLIP-seq
MIRT1250931	hsa-miR-520a-5p	CLIP-seq
MIRT1250932	hsa-miR-525-5p	CLIP-seq
MIRT1250933	hsa-miR-668	CLIP-seq
MIRT1250934	hsa-miR-939	CLIP-seq
MIRT1250935	hsa-miR-942	CLIP-seq
MIRT1552506	hsa-miR-3150b-3p	CLIP-seq
MIRT1552507	hsa-miR-4784	CLIP-seq
MIRT1250914	hsa-miR-370	CLIP-seq
MIRT2074066	hsa-miR-4492	CLIP-seq
MIRT2074067	hsa-miR-4498	CLIP-seq
MIRT1250927	hsa-miR-4731-5p	CLIP-seq
MIRT1250928	hsa-miR-4780	CLIP-seq
MIRT2074068	hsa-miR-762	CLIP-seq
MIRT2301015	hsa-miR-1287	CLIP-seq
MIRT2301016	hsa-miR-204	CLIP-seq
MIRT2301017	hsa-miR-211	CLIP-seq
MIRT2301018	hsa-miR-3135b	CLIP-seq
MIRT2301019	hsa-miR-3188	CLIP-seq
MIRT2301020	hsa-miR-331-3p	CLIP-seq
MIRT2301021	hsa-miR-3545-3p	CLIP-seq
MIRT2301022	hsa-miR-3612	CLIP-seq
MIRT2301023	hsa-miR-3661	CLIP-seq
MIRT1250914	hsa-miR-370	CLIP-seq
MIRT2301024	hsa-miR-4256	CLIP-seq
MIRT2301025	hsa-miR-4443	CLIP-seq
MIRT2301026	hsa-miR-4680-5p	CLIP-seq
MIRT2301027	hsa-miR-4725-5p	CLIP-seq
MIRT1250927	hsa-miR-4731-5p	CLIP-seq
MIRT1250928	hsa-miR-4780	CLIP-seq
MIRT2301028	hsa-miR-504	CLIP-seq
MIRT2301029	hsa-miR-631	CLIP-seq
MIRT2301030	hsa-miR-650	CLIP-seq
MIRT1250904	hsa-miR-659	CLIP-seq
MIRT2392858	hsa-miR-1267	CLIP-seq
MIRT2456923	hsa-miR-1185	CLIP-seq
MIRT2456924	hsa-miR-1255a	CLIP-seq
MIRT2456925	hsa-miR-1255b	CLIP-seq
MIRT2456926	hsa-miR-3605-5p	CLIP-seq
MIRT2456927	hsa-miR-3679-5p	CLIP-seq
MIRT2456928	hsa-miR-4709-3p	CLIP-seq
MIRT2456929	hsa-miR-765	CLIP-seq
MIRT2456926	hsa-miR-3605-5p	CLIP-seq

Show/Hide all (2)

Transcription factor	Regulation	Reference
NFKB1	Unknown	9360945
RELA	Unknown	9360945

Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000976	Function	Transcription cis-regulatory region binding	ISS
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0003700	Function	DNA-binding transcription factor activity	ISS
GO:0003700	Function	DNA-binding transcription factor activity	TAS	9442393
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IDA	9242494
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006959	Process	Humoral immune response	TAS	9442393
GO:0032755	Process	Positive regulation of interleukin-6 production	ISS
GO:0043565	Function	Sequence-specific DNA binding	IDA	9242494
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	ISS
GO:0098586	Process	Cellular response to virus	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
164176	9213	ENSG00000028277

P09086

Protein name

POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)

Protein function

Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to

PDB

1HDP , 9DZM

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00157	Pou	198 → 269	Pou domain - N-terminal to homeobox domain	Domain
PF00046	Homeodomain	298 → 354	Homeodomain	Domain

Tissue specificity

TISSUE SPECIFICITY: Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147. {ECO:0000269|PubMed:2904654, ECO:0000269|PubMed:3072196}.

Sequence

MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPS
TKIKAEDPSGDSAPAAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHL
QPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLS
HPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTT
ISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKK
RTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSA
APMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGG
GGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP

Sequence length

479

Interactions

View interactions

	KEGG		Reactome
	Herpes simplex virus 1 infection Lipid and atherosclerosis		RNA polymerase II transcribes snRNA genes

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
GASTRO-ENTEROPANCREATIC NEUROENDOCRINE TUMOR	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER, FAMILIAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (74)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	29127420		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Diffuse Large B-Cell Lymphoma	B-cell Lymphoma	BEFREE	12459631		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Hodgkin Lymphoma	Hodgkin Lymphoma	BEFREE	15796964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anodontia	Anodontia	Pubtator	11154228, 8639794	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	12507907, 15202521, 20331331, 28851661		★★★★★ ★☆☆☆☆ Found in Text Mining only
B-CELL MALIGNANCY, LOW-GRADE	Lymphocytic Leukemia	BEFREE	10905058		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	31420918, 39948777	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Lymphoma	Burkitt`s Lymphoma	LHGDN	14707079		★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Lymphoma	Burkitt lymphoma	Pubtator	22346751	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	31088315	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervical Intraepithelial Neoplasia	Cervical Intraepithelial Neoplasia	BEFREE	30119251		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	BEFREE	30168369		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Kidney Diseases	Kidney Disease	BEFREE	28483424		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	10905058		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	20551056		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	28992563	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	27440728, 31088315, 31649850		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	29551575		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	32041280	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	27609360		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diffuse Large B-Cell Lymphoma	Diffuse Lymphoma	BEFREE	12459631, 14694522, 28143608		★★★★★ ★☆☆☆☆ Found in Text Mining only
Essential Hypertension	Hypertension	BEFREE	17060063		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastro-enteropancreatic neuroendocrine tumor	Digestive system neuroendocrine neoplasm	CTD_human_DG	29915428		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hematologic Neoplasms	Hematologic neoplasm	Pubtator	26784514	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin Disease	BEFREE	11154228, 11280769, 15796964, 8639794		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	11154228, 16304050, 16648862, 19465900, 21424034, 8639794	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	15257313	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin Disease	LHGDN	15796964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington disease	Pubtator	11342448	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperuricemia	Hyperuricemia	BEFREE	30951542		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kaposi Sarcoma	Kaposi Sarcoma	BEFREE	19224997		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Failure, Acute	Kidney Failure	BEFREE	28414026		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	16891199, 17074681, 20141429, 23955454		★★★★★ ★☆☆☆☆ Found in Text Mining only
Linear atrophy	Atrophy	BEFREE	28955207		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	24643204, 33832481	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphedema	Lymphedema	Pubtator	11841448	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	16186795		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	16778825, 25318949	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma Follicular	Lymphoma	Pubtator	24435047	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma, Follicular	Lymphoma	BEFREE	24435047		★★★★★ ★☆☆☆☆ Found in Text Mining only
Machado-Joseph Disease	Machado-Joseph Disease	BEFREE	11850478		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	26019213		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	22223530, 27440728		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mediastinal (Thymic) Large B-Cell Lymphoma	B-Cell Lymphoma	BEFREE	28851661		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mouth Neoplasms	Mouth neoplasm	Pubtator	36170598	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	11841448	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	21438833, 29552153, 7600290		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	36629404	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasal Type Extranodal NK/T-Cell Lymphoma	Extranodal NK T Cell Lymphoma	BEFREE	21867533		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	22346751		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12072546, 12598320, 19504395, 21706474, 27435027		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	21314941, 23144874	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nodular Lymphocyte Predominant Hodgkin Lymphoma	Classical Hodgkin lymphoma	BEFREE	24525501, 28851661		★★★★★ ★☆☆☆☆ Found in Text Mining only
Paraplegia	Paraplegia	Pubtator	15308563	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pericardial effusion	Pericardial effusion	BEFREE	8639794		★★★★★ ★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	Pubtator	27302879	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor B-cell lymphoblastic leukemia	Lymphoblastic Leukemia	BEFREE	10905058		★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	Lymphoblastic Leukemia	BEFREE	10905058		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate cancer, familial	Prostate cancer	CTD_human_DG	29892016		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER, HEREDITARY, 1	Prostate Cancer, Hereditary	CTD_human_DG	29892016		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	27440728, 31088315, 31649850		★★★★★ ★☆☆☆☆ Found in Text Mining only
Respiratory Tract Diseases	Respiratory system infectious disease	Pubtator	37925496	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Retinal Diseases	Retinal Diseases	BEFREE	29160778		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	31644961		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sarcoma Kaposi	Sarcoma	Pubtator	19224997	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Secondary malignant neoplasm of colon and/or rectum	Colorectal Neoplasms	BEFREE	28992563		★★★★★ ★☆☆☆☆ Found in Text Mining only
Spermatocytic seminoma	Spermatocytic Seminoma	BEFREE	21706474		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	26019213		★★★★★ ★☆☆☆☆ Found in Text Mining only
Testicular Germ Cell Tumor	Testicular germ cell tumor	Pubtator	21706474	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Testicular Neoplasms	Testicular neoplasm	Pubtator	26784514	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	35616137	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Waldenstrom Macroglobulinemia	Waldenstrom`s Macroglobulinemia	BEFREE	24801987		★★★★★ ★☆☆☆☆ Found in Text Mining only
Waldenstrom Macroglobulinemia	Waldenstrom macroglobulinemia	Pubtator	24801987, 32457988	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Xanthomatosis, Cerebrotendinous	Cholestanol storage disease	BEFREE	20108380		★★★★★ ★☆☆☆☆ Found in Text Mining only

POU2F2 (POU class 2 homeobox 2)