Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5356
Gene name	Pleiotropic regulator 1
Gene symbol	PLRG1
Synonyms (NCBI Gene)	Cwc1PRL1PRP46PRPF46TANGO4
Chromosome	4
Chromosome location	4q31.3
Summary	This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alter

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miRTarBase ID	miRNA	Experiments	Reference
MIRT031549	hsa-miR-16-5p	Proteomics	18668040
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT666948	hsa-miR-7159-3p	HITS-CLIP	23824327
MIRT666947	hsa-miR-4482-3p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521854	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521854	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT031549	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT506139	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT506138	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT506137	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT506136	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT506135	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT506134	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT506133	hsa-miR-4517	PAR-CLIP	20371350
MIRT506132	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT506131	hsa-miR-3908	PAR-CLIP	20371350
MIRT506129	hsa-miR-7843-3p	PAR-CLIP	20371350
MIRT506128	hsa-miR-127-5p	PAR-CLIP	20371350
MIRT547090	hsa-miR-3609	PAR-CLIP	21572407
MIRT547089	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT547088	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT547087	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT547086	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT547085	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT547084	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT547083	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT547082	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT547081	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT547080	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT547079	hsa-miR-4495	PAR-CLIP	21572407
MIRT547078	hsa-miR-380-5p	PAR-CLIP	21572407
MIRT547077	hsa-miR-563	PAR-CLIP	21572407
MIRT521862	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT521861	hsa-miR-8485	PAR-CLIP	23446348
MIRT521860	hsa-miR-329-3p	PAR-CLIP	23446348
MIRT521859	hsa-miR-362-3p	PAR-CLIP	23446348
MIRT521858	hsa-miR-603	PAR-CLIP	23446348
MIRT521857	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT521856	hsa-miR-3941	PAR-CLIP	23446348
MIRT521855	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT521854	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT031549	hsa-miR-16-5p	PAR-CLIP	23446348
MIRT506139	hsa-miR-424-5p	PAR-CLIP	23446348
MIRT506138	hsa-miR-15a-5p	PAR-CLIP	23446348
MIRT506137	hsa-miR-15b-5p	PAR-CLIP	23446348
MIRT506136	hsa-miR-497-5p	PAR-CLIP	23446348
MIRT506135	hsa-miR-6838-5p	PAR-CLIP	23446348
MIRT506134	hsa-miR-195-5p	PAR-CLIP	23446348
MIRT506133	hsa-miR-4517	PAR-CLIP	23446348
MIRT506132	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT506131	hsa-miR-3908	PAR-CLIP	23446348
MIRT506129	hsa-miR-7843-3p	PAR-CLIP	23446348
MIRT506128	hsa-miR-127-5p	PAR-CLIP	23446348
MIRT031549	hsa-miR-16-5p	PAR-CLIP	23446348
MIRT506139	hsa-miR-424-5p	PAR-CLIP	23446348
MIRT506138	hsa-miR-15a-5p	PAR-CLIP	23446348
MIRT506137	hsa-miR-15b-5p	PAR-CLIP	23446348
MIRT506136	hsa-miR-497-5p	PAR-CLIP	23446348
MIRT506135	hsa-miR-6838-5p	PAR-CLIP	23446348
MIRT506134	hsa-miR-195-5p	PAR-CLIP	23446348
MIRT506133	hsa-miR-4517	PAR-CLIP	23446348
MIRT506132	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT506131	hsa-miR-3908	PAR-CLIP	23446348
MIRT506130	hsa-miR-5701	PAR-CLIP	23446348
MIRT506129	hsa-miR-7843-3p	PAR-CLIP	23446348
MIRT506128	hsa-miR-127-5p	PAR-CLIP	23446348
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT666948	hsa-miR-7159-3p	HITS-CLIP	23824327
MIRT666947	hsa-miR-4482-3p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521854	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521861	hsa-miR-8485	HITS-CLIP	23824327
MIRT521860	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT521859	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT521858	hsa-miR-603	HITS-CLIP	23824327
MIRT609457	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT609456	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT521857	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT609455	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT521856	hsa-miR-3941	HITS-CLIP	23824327
MIRT521855	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT521854	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT521862	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT031549	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT506139	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT506138	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT506137	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT506136	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT506135	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT506134	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT506133	hsa-miR-4517	PAR-CLIP	20371350
MIRT506132	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT506131	hsa-miR-3908	PAR-CLIP	20371350
MIRT506129	hsa-miR-7843-3p	PAR-CLIP	20371350
MIRT506128	hsa-miR-127-5p	PAR-CLIP	20371350
MIRT547090	hsa-miR-3609	PAR-CLIP	21572407
MIRT547089	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT547088	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT547087	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT547086	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT547085	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT547084	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT547083	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT547082	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT547081	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT547080	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT547079	hsa-miR-4495	PAR-CLIP	21572407
MIRT547078	hsa-miR-380-5p	PAR-CLIP	21572407
MIRT547077	hsa-miR-563	PAR-CLIP	21572407
MIRT521862	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT521861	hsa-miR-8485	PAR-CLIP	23446348
MIRT521860	hsa-miR-329-3p	PAR-CLIP	23446348
MIRT521859	hsa-miR-362-3p	PAR-CLIP	23446348
MIRT521858	hsa-miR-603	PAR-CLIP	23446348
MIRT521857	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT521856	hsa-miR-3941	PAR-CLIP	23446348
MIRT521855	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT521854	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT031549	hsa-miR-16-5p	PAR-CLIP	23446348
MIRT506139	hsa-miR-424-5p	PAR-CLIP	23446348
MIRT506138	hsa-miR-15a-5p	PAR-CLIP	23446348
MIRT506137	hsa-miR-15b-5p	PAR-CLIP	23446348
MIRT506136	hsa-miR-497-5p	PAR-CLIP	23446348
MIRT506135	hsa-miR-6838-5p	PAR-CLIP	23446348
MIRT506134	hsa-miR-195-5p	PAR-CLIP	23446348
MIRT506133	hsa-miR-4517	PAR-CLIP	23446348
MIRT506132	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT506131	hsa-miR-3908	PAR-CLIP	23446348
MIRT506129	hsa-miR-7843-3p	PAR-CLIP	23446348
MIRT506128	hsa-miR-127-5p	PAR-CLIP	23446348
MIRT031549	hsa-miR-16-5p	PAR-CLIP	23446348
MIRT506139	hsa-miR-424-5p	PAR-CLIP	23446348
MIRT506138	hsa-miR-15a-5p	PAR-CLIP	23446348
MIRT506137	hsa-miR-15b-5p	PAR-CLIP	23446348
MIRT506136	hsa-miR-497-5p	PAR-CLIP	23446348
MIRT506135	hsa-miR-6838-5p	PAR-CLIP	23446348
MIRT506134	hsa-miR-195-5p	PAR-CLIP	23446348
MIRT506133	hsa-miR-4517	PAR-CLIP	23446348
MIRT506132	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT506131	hsa-miR-3908	PAR-CLIP	23446348
MIRT506130	hsa-miR-5701	PAR-CLIP	23446348
MIRT506129	hsa-miR-7843-3p	PAR-CLIP	23446348
MIRT506128	hsa-miR-127-5p	PAR-CLIP	23446348
MIRT1243137	hsa-miR-1208	CLIP-seq
MIRT1243138	hsa-miR-1224-5p	CLIP-seq
MIRT1243139	hsa-miR-1303	CLIP-seq
MIRT1243140	hsa-miR-15a	CLIP-seq
MIRT1243141	hsa-miR-15b	CLIP-seq
MIRT1243142	hsa-miR-16	CLIP-seq
MIRT1243143	hsa-miR-195	CLIP-seq
MIRT1243144	hsa-miR-2115	CLIP-seq
MIRT1243145	hsa-miR-3163	CLIP-seq
MIRT1243146	hsa-miR-3662	CLIP-seq
MIRT1243147	hsa-miR-3915	CLIP-seq
MIRT1243148	hsa-miR-3923	CLIP-seq
MIRT1243149	hsa-miR-3928	CLIP-seq
MIRT1243150	hsa-miR-3938	CLIP-seq
MIRT1243151	hsa-miR-424	CLIP-seq
MIRT1243152	hsa-miR-4252	CLIP-seq
MIRT1243153	hsa-miR-4279	CLIP-seq
MIRT1243154	hsa-miR-4668-3p	CLIP-seq
MIRT1243155	hsa-miR-4689	CLIP-seq
MIRT1243156	hsa-miR-4694-5p	CLIP-seq
MIRT1243157	hsa-miR-4698	CLIP-seq
MIRT1243158	hsa-miR-495	CLIP-seq
MIRT1243159	hsa-miR-497	CLIP-seq
MIRT1243160	hsa-miR-516a-3p	CLIP-seq
MIRT1243145	hsa-miR-3163	CLIP-seq
MIRT2071856	hsa-miR-384	CLIP-seq
MIRT2071857	hsa-miR-4686	CLIP-seq
MIRT2071858	hsa-miR-548a-3p	CLIP-seq
MIRT2071859	hsa-miR-548e	CLIP-seq
MIRT2071860	hsa-miR-548f	CLIP-seq
MIRT2298972	hsa-miR-181a	CLIP-seq
MIRT2298973	hsa-miR-181b	CLIP-seq
MIRT2298974	hsa-miR-181c	CLIP-seq
MIRT2298975	hsa-miR-181d	CLIP-seq
MIRT2298976	hsa-miR-4262	CLIP-seq
MIRT2298977	hsa-miR-4484	CLIP-seq
MIRT2298978	hsa-miR-4504	CLIP-seq
MIRT2298979	hsa-miR-4509	CLIP-seq
MIRT2298980	hsa-miR-542-3p	CLIP-seq
MIRT2298981	hsa-miR-548an	CLIP-seq
MIRT2595772	hsa-miR-1587	CLIP-seq
MIRT2595773	hsa-miR-186	CLIP-seq
MIRT2595774	hsa-miR-3133	CLIP-seq
MIRT2595775	hsa-miR-4674	CLIP-seq
MIRT1243157	hsa-miR-4698	CLIP-seq
MIRT2595776	hsa-miR-4761-3p	CLIP-seq
MIRT2071856	hsa-miR-384	CLIP-seq
MIRT2688150	hsa-miR-1273e	CLIP-seq
MIRT2595772	hsa-miR-1587	CLIP-seq
MIRT2595773	hsa-miR-186	CLIP-seq
MIRT2688151	hsa-miR-18a	CLIP-seq
MIRT2688152	hsa-miR-18b	CLIP-seq
MIRT2595774	hsa-miR-3133	CLIP-seq
MIRT2688153	hsa-miR-3177-5p	CLIP-seq
MIRT2071856	hsa-miR-384	CLIP-seq
MIRT2595775	hsa-miR-4674	CLIP-seq
MIRT2071857	hsa-miR-4686	CLIP-seq
MIRT1243157	hsa-miR-4698	CLIP-seq
MIRT2688154	hsa-miR-4699-3p	CLIP-seq
MIRT2688155	hsa-miR-4735-3p	CLIP-seq
MIRT2595776	hsa-miR-4761-3p	CLIP-seq
MIRT2688156	hsa-miR-581	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
CDC5L	Unknown	11544257

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000398	Process	MRNA splicing, via spliceosome	IBA
GO:0000398	Process	MRNA splicing, via spliceosome	IC	11991638
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	28076346
GO:0000398	Process	MRNA splicing, via spliceosome	IEA
GO:0000398	Process	MRNA splicing, via spliceosome	NAS	23742842
GO:0000974	Component	Prp19 complex	IBA
GO:0000974	Component	Prp19 complex	IPI	20176811
GO:0001650	Component	Fibrillar center	IDA
GO:0005515	Function	Protein binding	IPI	17332742, 20176811, 20467437, 23022480, 32814053, 33961781, 35271311
GO:0005634	Component	Nucleus	IDA	28076346
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005662	Component	DNA replication factor A complex	IDA	24332808
GO:0005681	Component	Spliceosomal complex	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0016607	Component	Nuclear speck	IEA
GO:0031965	Component	Nuclear membrane	IDA
GO:0034504	Process	Protein localization to nucleus	IEA
GO:0071007	Component	U2-type catalytic step 2 spliceosome	IDA	28076346
GO:0071013	Component	Catalytic step 2 spliceosome	IBA
GO:0071013	Component	Catalytic step 2 spliceosome	IDA	11991638
GO:1900087	Process	Positive regulation of G1/S transition of mitotic cell cycle	IEA

MIM	HGNC	e!Ensembl
605961	9089	ENSG00000171566

O43660

Protein name

Pleiotropic regulator 1

Protein function

Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28076346, PubMed:28502770). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing (PubMed:111015

PDB

4YVD , 5MQF , 5XJC , 5YZG , 5Z56 , 5Z57 , 5Z58 , 6FF4 , 6FF7 , 6ICZ , 6ID0 , 6ID1 , 6QDV , 6ZYM , 7AAV , 7ABF , 7ABG , 7ABI , 7DH6 , 7DVQ , 7QTT , 7W59 , 7W5A , 7W5B , 8C6J , 8CH6 , 8I0P , 8I0R , 8I0S , 8I0T , 8I0U , 8I0V , 8I0W , 8RO2 , 9FMD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00400	WD40	194 → 232	WD domain, G-beta repeat	Repeat
PF00400	WD40	236 → 274	WD domain, G-beta repeat	Repeat
PF00400	WD40	278 → 316	WD domain, G-beta repeat	Repeat
PF00400	WD40	320 → 358	WD domain, G-beta repeat	Repeat
PF00400	WD40	403 → 440	WD domain, G-beta repeat	Repeat

Sequence

MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF

Sequence length

514

Interactions

View interactions

	KEGG		Reactome
	Spliceosome		mRNA Splicing - Major Pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
STROKE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (11)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	35290436	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	17234774, 20484558, 30462625		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	25003523, 30661451		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Failure	Liver failure	BEFREE	31653075		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	17234774, 20484558, 30462625		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	24968948		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	17234774, 21541048		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	18187808, 18684031, 23696794, 24939702		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	24968948		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	18684031		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	35831348	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

PLRG1 (pleiotropic regulator 1)