PGK1 (phosphoglycerate kinase 1)

Gene

• Entrez ID: 5230
• Gene name: Phosphoglycerate kinase 1
• Gene symbol: PGK1
• Synonyms (NCBI Gene): HEL-S-68p, MIG10, PGKA
• Chromosome: X
• Chromosome location: Xq21.1
• Summary: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cel

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs137852528	G>A	Pathogenic	Coding sequence variant, missense variant
rs137852529	G>A,C	Pathogenic	Coding sequence variant, missense variant
rs137852531	T>C	Pathogenic	Coding sequence variant, missense variant
rs137852532	G>T	Pathogenic	Coding sequence variant, missense variant
rs137852533	T>C	Pathogenic	Coding sequence variant, missense variant
rs137852534	T>C	Pathogenic-likely-pathogenic	Coding sequence variant, missense variant
rs137852535	A>T	Pathogenic	Coding sequence variant, missense variant
rs137852536	T>A	Pathogenic	Coding sequence variant, missense variant
rs137852537	G>A	Pathogenic	Coding sequence variant, missense variant
rs137852538	A>T	Pathogenic	Coding sequence variant, missense variant
rs137852539	A>C	Pathogenic	Coding sequence variant, missense variant
rs431905501	GTC>ATG	Pathogenic	Missense variant, coding sequence variant
rs431905502	AAG>-	Pathogenic	Inframe deletion, coding sequence variant
rs431905503	G>A	Pathogenic	Intron variant
rs782165735	G>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant
rs782667719	T>A	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, synonymous variant
rs797044505	C>T	Conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant
rs1057524140	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs1569550773	A>C	Likely-pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT050550	hsa-miR-20a-5p	CLASH	23622248
MIRT043151	hsa-miR-324-5p	CLASH	23622248
MIRT040970	hsa-miR-18a-3p	CLASH	23622248
MIRT717331	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT717330	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT717328	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT717323	hsa-miR-4433a-5p	HITS-CLIP	19536157
MIRT717322	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT717321	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT717320	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT717331	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT717330	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT717329	hsa-miR-4286	HITS-CLIP	19536157
MIRT717328	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT622788	hsa-miR-1913	HITS-CLIP	19536157
MIRT622787	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT717326	hsa-miR-5699-5p	HITS-CLIP	19536157
MIRT717327	hsa-miR-4758-3p	HITS-CLIP	19536157
MIRT717325	hsa-miR-3189-5p	HITS-CLIP	19536157
MIRT717324	hsa-miR-6882-3p	HITS-CLIP	19536157
MIRT717323	hsa-miR-4433a-5p	HITS-CLIP	19536157
MIRT717322	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT717321	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT717320	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622792	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622788	hsa-miR-1913	HITS-CLIP	23824327
MIRT622787	hsa-miR-324-3p	HITS-CLIP	23824327
MIRT040970	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT176163	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT544141	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT329668	hsa-miR-548n	PAR-CLIP	21572407
MIRT329671	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT329669	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT544140	hsa-miR-6835-3p	PAR-CLIP	21572407
MIRT329670	hsa-miR-548at-5p	PAR-CLIP	21572407
MIRT544139	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT528397	hsa-miR-3133	PAR-CLIP	22012620
MIRT528396	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT176151	hsa-miR-141-3p	PAR-CLIP	22012620
MIRT176153	hsa-miR-200a-3p	PAR-CLIP	22012620
MIRT528395	hsa-miR-548b-3p	PAR-CLIP	22012620
MIRT528394	hsa-miR-4744	PAR-CLIP	22012620
MIRT528393	hsa-miR-570-3p	PAR-CLIP	22012620
MIRT528392	hsa-miR-610	PAR-CLIP	22012620
MIRT445734	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445733	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445732	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445731	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445730	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445729	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445728	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445726	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445727	hsa-miR-3646	PAR-CLIP	22100165
MIRT176177	hsa-miR-3185	PAR-CLIP	22100165
MIRT445725	hsa-miR-27b-5p	PAR-CLIP	22100165
MIRT439994	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT439994	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT726964	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT726963	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT733732	hsa-miR-6869-5p	Luciferase reporter assay, qRT-PCR, Western blotting	32565733
MIRT717331	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT717330	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT717328	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT717323	hsa-miR-4433a-5p	HITS-CLIP	19536157
MIRT717322	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT717321	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT717320	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT717331	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT717330	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT717329	hsa-miR-4286	HITS-CLIP	19536157
MIRT717328	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT622788	hsa-miR-1913	HITS-CLIP	19536157
MIRT622787	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT717326	hsa-miR-5699-5p	HITS-CLIP	19536157
MIRT717327	hsa-miR-4758-3p	HITS-CLIP	19536157
MIRT717325	hsa-miR-3189-5p	HITS-CLIP	19536157
MIRT717324	hsa-miR-6882-3p	HITS-CLIP	19536157
MIRT717323	hsa-miR-4433a-5p	HITS-CLIP	19536157
MIRT717322	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT717321	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT717320	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622792	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622788	hsa-miR-1913	HITS-CLIP	23824327
MIRT622787	hsa-miR-324-3p	HITS-CLIP	23824327
MIRT040970	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT176163	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT544141	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT329668	hsa-miR-548n	PAR-CLIP	21572407
MIRT329671	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT329669	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT544140	hsa-miR-6835-3p	PAR-CLIP	21572407
MIRT329670	hsa-miR-548at-5p	PAR-CLIP	21572407
MIRT544139	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT528397	hsa-miR-3133	PAR-CLIP	22012620
MIRT528396	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT176151	hsa-miR-141-3p	PAR-CLIP	22012620
MIRT176153	hsa-miR-200a-3p	PAR-CLIP	22012620
MIRT528395	hsa-miR-548b-3p	PAR-CLIP	22012620
MIRT528394	hsa-miR-4744	PAR-CLIP	22012620
MIRT528393	hsa-miR-570-3p	PAR-CLIP	22012620
MIRT528392	hsa-miR-610	PAR-CLIP	22012620
MIRT445734	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445733	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445732	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445731	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445730	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445729	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445728	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445726	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445727	hsa-miR-3646	PAR-CLIP	22100165
MIRT176177	hsa-miR-3185	PAR-CLIP	22100165
MIRT445725	hsa-miR-27b-5p	PAR-CLIP	22100165
MIRT756184	hsa-miR-346	Luciferase reporter assay, Western blotting, qRT-PCR, Flow cytometry	38091240
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT1227448	hsa-miR-1207-3p	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT1227450	hsa-miR-1283	CLIP-seq
MIRT1227451	hsa-miR-1343	CLIP-seq
MIRT1227452	hsa-miR-141	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227456	hsa-miR-200a	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT1227458	hsa-miR-299-3p	CLIP-seq
MIRT1227459	hsa-miR-299-5p	CLIP-seq
MIRT1227460	hsa-miR-3121-3p	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227463	hsa-miR-3190	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT1227465	hsa-miR-3606	CLIP-seq
MIRT1227466	hsa-miR-3614-3p	CLIP-seq
MIRT1227467	hsa-miR-3667-3p	CLIP-seq
MIRT1227468	hsa-miR-3668	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT1227470	hsa-miR-3924	CLIP-seq
MIRT1227471	hsa-miR-4297	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227475	hsa-miR-4491	CLIP-seq
MIRT1227476	hsa-miR-4504	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227481	hsa-miR-4657	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT1227483	hsa-miR-4663	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227486	hsa-miR-4691-5p	CLIP-seq
MIRT1227487	hsa-miR-4694-3p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT1227493	hsa-miR-4728-3p	CLIP-seq
MIRT1227494	hsa-miR-4742-3p	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT1227497	hsa-miR-4795-5p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227500	hsa-miR-494	CLIP-seq
MIRT1227501	hsa-miR-501-3p	CLIP-seq
MIRT1227502	hsa-miR-502-3p	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227506	hsa-miR-587	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT2066616	hsa-miR-1270	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT1227450	hsa-miR-1283	CLIP-seq
MIRT1227451	hsa-miR-1343	CLIP-seq
MIRT1227452	hsa-miR-141	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227456	hsa-miR-200a	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT2066617	hsa-miR-298	CLIP-seq
MIRT1227459	hsa-miR-299-5p	CLIP-seq
MIRT2066618	hsa-miR-3150a-3p	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT2066619	hsa-miR-3175	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT2066620	hsa-miR-326	CLIP-seq
MIRT2066621	hsa-miR-330-5p	CLIP-seq
MIRT2066622	hsa-miR-3545-5p	CLIP-seq
MIRT2066623	hsa-miR-365	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT2066624	hsa-miR-4480	CLIP-seq
MIRT2066625	hsa-miR-4481	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT2066626	hsa-miR-4667-5p	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT2066627	hsa-miR-4683	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227487	hsa-miR-4694-3p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT2066628	hsa-miR-4700-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT2066629	hsa-miR-4745-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT2066630	hsa-miR-4790-3p	CLIP-seq
MIRT2066631	hsa-miR-4796-3p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT2066632	hsa-miR-488	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227500	hsa-miR-494	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT2066633	hsa-miR-620	CLIP-seq
MIRT2066634	hsa-miR-637	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT2066635	hsa-miR-939	CLIP-seq
MIRT2294161	hsa-miR-103b	CLIP-seq
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT1227450	hsa-miR-1283	CLIP-seq
MIRT1227451	hsa-miR-1343	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT2294162	hsa-miR-219-1-3p	CLIP-seq
MIRT2066618	hsa-miR-3150a-3p	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT2066619	hsa-miR-3175	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT2066620	hsa-miR-326	CLIP-seq
MIRT2066621	hsa-miR-330-5p	CLIP-seq
MIRT2294163	hsa-miR-335	CLIP-seq
MIRT2294164	hsa-miR-33a	CLIP-seq
MIRT2294165	hsa-miR-33b	CLIP-seq
MIRT2066622	hsa-miR-3545-5p	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT2294166	hsa-miR-376c	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT2066625	hsa-miR-4481	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT2066626	hsa-miR-4667-5p	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227487	hsa-miR-4694-3p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT2066628	hsa-miR-4700-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT2066629	hsa-miR-4745-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT2066631	hsa-miR-4796-3p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT2066632	hsa-miR-488	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT2294167	hsa-miR-548ae	CLIP-seq
MIRT2294168	hsa-miR-548aj	CLIP-seq
MIRT2294169	hsa-miR-548am	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT2294170	hsa-miR-548x	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT2066634	hsa-miR-637	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT2066635	hsa-miR-939	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT2066616	hsa-miR-1270	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT2592145	hsa-miR-1323	CLIP-seq
MIRT1227452	hsa-miR-141	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT2592146	hsa-miR-146a	CLIP-seq
MIRT2592147	hsa-miR-146b-5p	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227456	hsa-miR-200a	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT2066617	hsa-miR-298	CLIP-seq
MIRT1227458	hsa-miR-299-3p	CLIP-seq
MIRT1227459	hsa-miR-299-5p	CLIP-seq
MIRT1227460	hsa-miR-3121-3p	CLIP-seq
MIRT2592148	hsa-miR-3123	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227463	hsa-miR-3190	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT1227466	hsa-miR-3614-3p	CLIP-seq
MIRT2066623	hsa-miR-365	CLIP-seq
MIRT1227467	hsa-miR-3667-3p	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT2592149	hsa-miR-3714	CLIP-seq
MIRT2592150	hsa-miR-382	CLIP-seq
MIRT2592151	hsa-miR-3925-5p	CLIP-seq
MIRT2592152	hsa-miR-4278	CLIP-seq
MIRT1227471	hsa-miR-4297	CLIP-seq
MIRT2592153	hsa-miR-4311	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT2066624	hsa-miR-4480	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227475	hsa-miR-4491	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT2592154	hsa-miR-4523	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT2592155	hsa-miR-4639-5p	CLIP-seq
MIRT1227481	hsa-miR-4657	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT2592156	hsa-miR-4675	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT2066627	hsa-miR-4683	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT2592157	hsa-miR-4688	CLIP-seq
MIRT1227486	hsa-miR-4691-5p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT2592158	hsa-miR-4741	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT1227497	hsa-miR-4795-5p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT2592159	hsa-miR-499-3p	CLIP-seq
MIRT2592160	hsa-miR-499a-3p	CLIP-seq
MIRT1227501	hsa-miR-501-3p	CLIP-seq
MIRT1227502	hsa-miR-502-3p	CLIP-seq
MIRT2592161	hsa-miR-548an	CLIP-seq
MIRT2592162	hsa-miR-548o	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT2066633	hsa-miR-620	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT2592163	hsa-miR-873	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT2592164	hsa-miR-940	CLIP-seq
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT2066616	hsa-miR-1270	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT2592145	hsa-miR-1323	CLIP-seq
MIRT1227451	hsa-miR-1343	CLIP-seq
MIRT1227452	hsa-miR-141	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT2592146	hsa-miR-146a	CLIP-seq
MIRT2592147	hsa-miR-146b-5p	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227456	hsa-miR-200a	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT2066617	hsa-miR-298	CLIP-seq
MIRT1227458	hsa-miR-299-3p	CLIP-seq
MIRT1227459	hsa-miR-299-5p	CLIP-seq
MIRT1227460	hsa-miR-3121-3p	CLIP-seq
MIRT2592148	hsa-miR-3123	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227463	hsa-miR-3190	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT1227466	hsa-miR-3614-3p	CLIP-seq
MIRT2066623	hsa-miR-365	CLIP-seq
MIRT1227467	hsa-miR-3667-3p	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT2592149	hsa-miR-3714	CLIP-seq
MIRT2592150	hsa-miR-382	CLIP-seq
MIRT2592151	hsa-miR-3925-5p	CLIP-seq
MIRT2592152	hsa-miR-4278	CLIP-seq
MIRT1227471	hsa-miR-4297	CLIP-seq
MIRT2592153	hsa-miR-4311	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT2066624	hsa-miR-4480	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227475	hsa-miR-4491	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT2592154	hsa-miR-4523	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT2592155	hsa-miR-4639-5p	CLIP-seq
MIRT1227481	hsa-miR-4657	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT2592156	hsa-miR-4675	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT2066627	hsa-miR-4683	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT2592157	hsa-miR-4688	CLIP-seq
MIRT1227486	hsa-miR-4691-5p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT2592158	hsa-miR-4741	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT1227497	hsa-miR-4795-5p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT2592159	hsa-miR-499-3p	CLIP-seq
MIRT2592160	hsa-miR-499a-3p	CLIP-seq
MIRT1227501	hsa-miR-501-3p	CLIP-seq
MIRT1227502	hsa-miR-502-3p	CLIP-seq
MIRT2592161	hsa-miR-548an	CLIP-seq
MIRT2592162	hsa-miR-548o	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT2066633	hsa-miR-620	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT2592163	hsa-miR-873	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT2592164	hsa-miR-940	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
HIF1A	Activation	8089148
MYC	Unknown	18809243

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004618	Function	Phosphoglycerate kinase activity	EXP	1278465, 5009693
GO:0004618	Function	Phosphoglycerate kinase activity	IBA
GO:0004618	Function	Phosphoglycerate kinase activity	IEA
GO:0004618	Function	Phosphoglycerate kinase activity	IMP	7391028
GO:0004618	Function	Phosphoglycerate kinase activity	ISS
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	26942675
GO:0005515	Function	Protein binding	IPI	20392205, 20849852, 26030842, 26356530, 26942675, 28514442, 32707033, 33961781, 35271311
GO:0005524	Function	ATP binding	IBA
GO:0005524	Function	ATP binding	IEA
GO:0005524	Function	ATP binding	ISS
GO:0005615	Component	Extracellular space	IDA	11130727
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0005759	Component	Mitochondrial matrix	IDA	26942675, 36849569
GO:0005759	Component	Mitochondrial matrix	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	36849569
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006094	Process	Gluconeogenesis	IBA
GO:0006094	Process	Gluconeogenesis	IEA
GO:0006094	Process	Gluconeogenesis	TAS
GO:0006096	Process	Glycolytic process	IBA
GO:0006096	Process	Glycolytic process	IEA
GO:0006096	Process	Glycolytic process	IEA
GO:0006096	Process	Glycolytic process	IMP	7391028
GO:0016020	Component	Membrane	HDA	19946888
GO:0016301	Function	Kinase activity	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IMP	11130727
GO:0016740	Function	Transferase activity	IEA
GO:0030855	Process	Epithelial cell differentiation	IEP	21492153
GO:0031639	Process	Plasminogen activation	IMP	11130727
GO:0043531	Function	ADP binding	IBA
GO:0044325	Function	Transmembrane transporter binding	IEA
GO:0045121	Component	Membrane raft	IDA	25204797
GO:0046872	Function	Metal ion binding	IEA
GO:0047134	Function	Protein-disulfide reductase [NAD(P)H] activity	IMP	11130727
GO:0061621	Process	Canonical glycolysis	IEA
GO:0061621	Process	Canonical glycolysis	TAS
GO:0070062	Component	Extracellular exosome	HDA	11487543, 19199708, 20458337, 23533145
GO:0071456	Process	Cellular response to hypoxia	IDA	11130727
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0160218	Process	Negative regulation of pyruvate decarboxylation to acetyl-CoA	IDA	26942675

Other IDs

• MIM: 311800
• HGNC: 8896
• e!Ensembl: ENSG00000102144

Protein

• UniProt ID: P00558
• Protein name: Phosphoglycerate kinase 1 (EC 2.7.11.1) (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)
• Protein function: Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate (PubMed:30323285, PubMed:7391028). Both L- and D- forms of purine and pyrimidine nucleotides
• PDB: 2WZB, 2WZC, 2WZD, 2X13, 2X14, 2X15, 2XE6, 2XE7, 2XE8, 2Y3I, 2YBE, 2ZGV, 3C39, 3C3A, 3C3B, 3C3C, 3ZOZ, 4AXX, 4O33, 5M1R, 5M3U, 5M6Z, 5MXM, 5NP8, 5O7D, 8YHP
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00162	PGK	9 → 406	Phosphoglycerate kinase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Mainly expressed in spermatogonia. Localized on the principle piece in the sperm (at protein level). Expression significantly decreased in the testis of elderly men. {ECO:0000269|PubMed:26677959}.
• Sequence:

  MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL
  MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE
  NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
  LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM
  AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ
  ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV
  KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI

• Sequence length: 417

Pathways

KEGG:

Glycolysis / Gluconeogenesis
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
HIF-1 signaling pathway

Reactome:

Glycolysis
Gluconeogenesis
Manipulation of host energy metabolism

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Glycogen storage disease due to phosphoglycerate kinase 1 deficiency	Likely pathogenic; Pathogenic	rs2149132078, rs137852528, rs137852529, rs431905501, rs137852531, rs137852532, rs137852533, rs137852535, rs137852536, rs137852537, rs137852538, rs431905503, rs137852539	RCV002250801 RCV000010620 RCV000010621 RCV000010622 RCV000010624 RCV000010625 RCV000010626 RCV000010629 RCV000010630 RCV000010631 RCV000010632 RCV000010633 RCV000010634	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Male infertility due to obstructive azoospermia	Likely pathogenic	rs1569550773	RCV000767230	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANEMIA, HEMOLYTIC	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, HEPATOCELLULAR	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, RENAL CELL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Epilepsy	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Epileptic encephalopathy	Uncertain significance	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Familial cancer of breast	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hereditary skeletal muscle disorder	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Intellectual disability	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Optic atrophy	Likely benign	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
PGK1-related disorder	Uncertain significance; Conflicting classifications of pathogenicity; Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Phosphoglycerate kinase electrophoretic variant PGK II	other	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Profound global developmental delay	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RETINITIS PIGMENTOSA 1	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uveal melanoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	31361595		★☆☆☆☆ Found in Text Mining only
Anemia	Anemia	BEFREE	1683796, 30951021		★☆☆☆☆ Found in Text Mining only
Anemia Hemolytic	Hemolytic anemia	Pubtator	16412025, 39787833	Associate	★☆☆☆☆ Found in Text Mining only
Anemia, Hemolytic	Anemia	BEFREE	16857429, 30975619		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Anemia, Hemolytic	Anemia	HPO_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	16493704, 31611300		★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	Pubtator	22742733	Associate	★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	BEFREE	24284928		★☆☆☆☆ Found in Text Mining only
Bone Diseases Metabolic	Bone disease	Pubtator	22619369	Associate	★☆☆☆☆ Found in Text Mining only
Bone Marrow Diseases	Bone marrow diseases	Pubtator	24376734	Associate	★☆☆☆☆ Found in Text Mining only
Brain Diseases Metabolic Inborn	Brain disease	Pubtator	39787833	Associate	★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain Neoplasms	BEFREE	31492635		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	23130662, 25867275, 30537744		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	16048908, 30537744, 31578148, 32028979, 32070368, 33597614, 34600547, 34790279, 34868337, 35441810, 36077333, 36860848, 37190091, 37986376, 39192221, 39684297	Associate	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	25867275, 36388159	Stimulate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	32489020, 39456901, 39684297	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	18453750		★☆☆☆☆ Found in Text Mining only
Carcinoma Adenoid Cystic	Adenoid cystic carcinoma	Pubtator	37741973	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	19200351, 28749413	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	12558872, 25573171		★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	32241274, 38098044	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	33564363	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	25096996		★☆☆☆☆ Found in Text Mining only
Carcinomatosis of peritoneal cavity	Peritoneal Carcinomatosis	BEFREE	18453750, 19688824		★☆☆☆☆ Found in Text Mining only
Carcinosarcoma	Carcinoma	Pubtator	32439920	Associate	★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	BEFREE	20331858		★☆☆☆☆ Found in Text Mining only
Cataract	Cataract	Pubtator	34055996	Associate	★☆☆☆☆ Found in Text Mining only
Charcot-Marie-Tooth Disease	Charcot-Marie-Tooth Disease	BEFREE	30887539		★☆☆☆☆ Found in Text Mining only
Charcot-Marie-Tooth disease, X-linked, 1	Charcot-Marie-Tooth disease	BEFREE	8304339		★☆☆☆☆ Found in Text Mining only
Chordoma	Chordoma	Pubtator	38282590	Associate	★☆☆☆☆ Found in Text Mining only
Christ-Siemens-Touraine syndrome	Hypohidrotic Ectodermal Dysplasia, X-Linked	BEFREE	1357963		★☆☆☆☆ Found in Text Mining only
Chromophobe Renal Cell Carcinoma	Chromophobe Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Chronic Disease	Chronic disease	Pubtator	34975312	Associate	★☆☆☆☆ Found in Text Mining only
Collecting Duct Carcinoma of the Kidney	Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	15355913, 23727790		★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	18603805	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	30420909, 31797757		★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	20331858		★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	29882248		★☆☆☆☆ Found in Text Mining only
Cutis laxa, x-linked	Cutis Laxa, X-Linked	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Deficiency of phosphoglycerate kinase	Deficiency Of Phosphoglycerate Kinase	ORPHANET_DG	1547346		★☆☆☆☆ Found in Text Mining only
Deficiency of phosphoglycerate kinase	Deficiency Of Phosphoglycerate Kinase	BEFREE	16671097, 16740138, 17661373, 30951021		★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	16740138	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	19582723	Associate	★☆☆☆☆ Found in Text Mining only
Dystonia 3, Torsion, X-Linked	Dystonia	BEFREE	1550125		★☆☆☆☆ Found in Text Mining only
Ectodermal Dysplasia	Ectodermal dysplasia	Pubtator	1357963	Associate	★☆☆☆☆ Found in Text Mining only
Ectodermal Dysplasia 1 Anhidrotic	Ectodermal dysplasia	Pubtator	3163892	Associate	★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	29416645, 30679932, 30925862		★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	32439920	Associate	★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	36966136	Associate	★☆☆☆☆ Found in Text Mining only
Gallbladder Carcinoma	Gallbladder cancer	BEFREE	30953511		★☆☆☆☆ Found in Text Mining only
Gallbladder Neoplasms	Gallbladder neoplasm	Pubtator	26656369	Inhibit	★☆☆☆☆ Found in Text Mining only
Gastrointestinal Diseases	Gastrointestinal disease	Pubtator	35008842	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	28994107, 31492635		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	37408007	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	28994107, 30029001, 31492635		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	25175369, 28903403		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	32565733	Associate	★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
Glycogen Storage Disease	Glycogen Storage Disease	GENOMICS_ENGLAND_DG			★☆☆☆☆ Found in Text Mining only
Glycogen storage disease due to phosphoglycerate kinase 1 deficiency	Glycogen Storage Disease	Orphanet			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Heart failure	Heart Failure	BEFREE	20331858		★☆☆☆☆ Found in Text Mining only
Hemophilia A	Hemophilia a	Pubtator	34445777	Associate	★☆☆☆☆ Found in Text Mining only
Hereditary spherocytosis	Hereditary Spherocytosis	BEFREE	30951021		★☆☆☆☆ Found in Text Mining only
Hurthle Cell Tumor	Tumor	BEFREE	31514886		★☆☆☆☆ Found in Text Mining only
Hyperbilirubinemia	Hyperbilirubinemia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	27625398, 33941139	Associate	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	27765905, 36230969	Stimulate	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	16567715		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Intellectual Disability	Mental retardation	HPO_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Liver carcinoma	Liver carcinoma	BEFREE	19200351, 21471709, 28749413, 31114342, 31222833, 9692838		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	CTD_human_DG	21472284		★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	9692838		★☆☆☆☆ Found in Text Mining only
Lung Diseases	Lung disease	Pubtator	27625398	Associate	★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus	Lupus Erythematosus	BEFREE	16857429		★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Discoid	Lupus Erythematosus	BEFREE	16857429		★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	16857429		★☆☆☆☆ Found in Text Mining only
Lupus Vulgaris	Lupus Vulgaris	BEFREE	16857429		★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	20037605	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	23130662, 25867275, 30537744		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of endometrium	Endometrial Cancer	BEFREE	30679932, 30925862		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	31578148		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of gallbladder	Gallbladder cancer	BEFREE	30953511		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	27774669		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	12558872, 25573171		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	25096996		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	31255446, 31611300, 31827081		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	19825988, 21454517, 21780947, 22805767, 28391351		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	18453750, 19688824, 20798498		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	23727790, 25867275, 26942675, 30679932, 31578148, 31815035		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	15355913, 23727790		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	16048908		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	21454517		★☆☆☆☆ Found in Text Mining only
Menkes Kinky Hair Syndrome	Menkes Kinky Hair Syndrome	BEFREE	2035533, 7959788		★☆☆☆☆ Found in Text Mining only
Menkes Kinky Hair Syndrome	Menkes Kinky Hair Syndrome	CLINVAR_DG	21494555		★☆☆☆☆ Found in Text Mining only
Mental Retardation	Mental retardation	BEFREE	16567715		★☆☆☆☆ Found in Text Mining only
Migraine Disorders	Migraine	HPO_DG			★☆☆☆☆ Found in Text Mining only
Mood swings	Mood swings	HPO_DG			★☆☆☆☆ Found in Text Mining only
Mucocutaneous Lymph Node Syndrome	Kawasaki disease	BEFREE	30113070		★☆☆☆☆ Found in Text Mining only
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	1356510		★☆☆☆☆ Found in Text Mining only
Myopathy	Myopathy	BEFREE	20151463, 30951021, 30975619		★☆☆☆☆ Found in Text Mining only
Myopathy	Myopathy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Necrosis	Necrosis	Pubtator	31767834	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	15355913, 16493704, 17210694, 19688824, 20798498, 20961996, 26510737, 28994107, 30471866, 30537744, 31222833, 31326556, 8150459, 9745428		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	20961996, 26510737		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	24376734, 27765905	Associate	★☆☆☆☆ Found in Text Mining only
Neuromuscular Diseases	Neuromuscular disease	Pubtator	39787833	Associate	★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	25573171, 28923857, 30471866, 30662561		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	37894825	Associate	★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	22619369	Associate	★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	25096996		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	25096996	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	31255446, 31611300, 31827081		★☆☆☆☆ Found in Text Mining only
Pancreatic Ductal Adenocarcinoma	Pancreatic adenocarcinoma	BEFREE	16493704		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	19582723, 36807568	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatitis Chronic	Pancreatitis	Pubtator	19582723	Associate	★☆☆☆☆ Found in Text Mining only
Papillary Renal Cell Carcinoma	Papillary Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	31524631		★☆☆☆☆ Found in Text Mining only
Peritoneal Neoplasms	Peritoneal neoplasm	Pubtator	19688824	Stimulate	★☆☆☆☆ Found in Text Mining only
Peritonitis	Peritonitis	Pubtator	19688824	Associate	★☆☆☆☆ Found in Text Mining only
Phosphoglycerate Kinase 1 Deficiency	Phosphoglycerate Kinase 1 Deficiency	BEFREE	12956773, 16671097, 16740138, 17661373, 24934115, 30951021, 30975619		★☆☆☆☆ Found in Text Mining only
Phosphoglycerate Kinase 1 Deficiency	Phosphoglycerate Kinase 1 Deficiency	ORPHANET_DG	1547346		★☆☆☆☆ Found in Text Mining only
Phosphoglycerate Kinase 1 Deficiency	Phosphoglycerate Kinase 1 Deficiency	UNIPROT_DG	1547346, 1586722, 2001457, 6933565, 6941312, 8043870, 8615693, 8673469, 9744480		★☆☆☆☆ Found in Text Mining only
Phosphoglycerate Kinase 1 Deficiency	Phosphoglycerate Kinase 1 Deficiency	GENOMICS_ENGLAND_DG	1547346, 16740138, 27604308, 6933565		★☆☆☆☆ Found in Text Mining only
Phosphoglycerate Kinase 1 Deficiency	Phosphoglycerate Kinase 1 Deficiency	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Phosphoglycerate Kinase 1 Deficiency	Phosphoglycerate Kinase 1 Deficiency	CTD_human_DG			★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	11745195, 19825988, 21454517, 21780947, 22805767, 28391351		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	19893039, 22805767, 29954422, 37894825	Associate	★☆☆☆☆ Found in Text Mining only
Pulmonary Arterial Hypertension	Pulmonary arterial hypertension	Pubtator	35960497	Stimulate	★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	29882248		★☆☆☆☆ Found in Text Mining only
Renal Insufficiency	Renal Insufficiency	HPO_DG			★☆☆☆☆ Found in Text Mining only
Retinal Dystrophies	Retinal Dystrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Retinitis Pigmentosa 10	Retinitis Pigmentosa	BEFREE	16671097		★☆☆☆☆ Found in Text Mining only
Rhegmatogenous retinal detachment	Rhegmatogenous retinal detachment	BEFREE	29641463		★☆☆☆☆ Found in Text Mining only
Rhegmatogenous Retinal Detachment Autosomal Dominant	Rhegmatogenous retinal detachment	Pubtator	29641463	Associate	★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	27342824		★☆☆☆☆ Found in Text Mining only
Sarcomatoid Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	LHGDN	19110265		★☆☆☆☆ Found in Text Mining only
Seizures	Seizures	Pubtator	16740138	Associate	★☆☆☆☆ Found in Text Mining only
Severe Combined Immunodeficiency	Severe combined immunodeficiency	Pubtator	2565084, 8317482	Associate	★☆☆☆☆ Found in Text Mining only
Spinal Muscular Atrophy	Spinal Muscular Atrophy	BEFREE	28426667		★☆☆☆☆ Found in Text Mining only
Spinal Muscular Atrophy, Distal, X-Linked 3	Spinal Muscular Atrophy, X-Linked	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	33941139, 34599215, 34668665, 38035710, 38256104, 39456901	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	18453750, 19688824, 20798498		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	19688824, 31578148, 36684675	Associate	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	32350346, 36077333, 40634657	Associate	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	37190091	Stimulate	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	39315723	Stimulate	★☆☆☆☆ Found in Text Mining only
Urogenital Abnormalities	Urogenital Abnormalities	BEFREE	11745195		★☆☆☆☆ Found in Text Mining only
Wiskott-Aldrich Syndrome	Wiskott-Aldrich Syndrome	BEFREE	2328995		★☆☆☆☆ Found in Text Mining only
X-Linked Combined Immunodeficiency Diseases	Combined Immunodeficiency, X-Linked	BEFREE	2606471		★☆☆☆☆ Found in Text Mining only