Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5218
Gene name	Cyclin dependent kinase 14
Gene symbol	CDK14
Synonyms (NCBI Gene)	PFTAIRE1PFTK1
Chromosome	7
Chromosome location	7q21.13
Summary	PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]

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Show/Hide all (306)

miRTarBase ID	miRNA	Experiments	Reference
MIRT003763	hsa-miR-1-3p	Microarray	15685193
MIRT003763	hsa-miR-1-3p	Microarray	15685193
MIRT024450	hsa-miR-215-5p	Microarray	19074876
MIRT026414	hsa-miR-192-5p	Microarray	19074876
MIRT029296	hsa-miR-26b-5p	Microarray	19088304
MIRT487715	hsa-miR-4428	PAR-CLIP	23592263
MIRT487714	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT487713	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT487712	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT487711	hsa-miR-1321	PAR-CLIP	23592263
MIRT487710	hsa-miR-4739	PAR-CLIP	23592263
MIRT487709	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT487707	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT487708	hsa-miR-4419a	PAR-CLIP	23592263
MIRT487706	hsa-miR-4510	PAR-CLIP	23592263
MIRT487705	hsa-miR-6127	PAR-CLIP	23592263
MIRT487704	hsa-miR-6129	PAR-CLIP	23592263
MIRT487703	hsa-miR-6130	PAR-CLIP	23592263
MIRT487702	hsa-miR-6133	PAR-CLIP	23592263
MIRT487701	hsa-miR-4533	PAR-CLIP	23592263
MIRT487700	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT487699	hsa-miR-4306	PAR-CLIP	23592263
MIRT487698	hsa-miR-4644	PAR-CLIP	23592263
MIRT487697	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT487696	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT487695	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT487694	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT487693	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT487692	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT487690	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT487691	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT487689	hsa-miR-4271	PAR-CLIP	23592263
MIRT487688	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT487687	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT440965	hsa-miR-493-5p	HITS-CLIP	24374217
MIRT440964	hsa-miR-376c-3p	HITS-CLIP	24374217
MIRT440965	hsa-miR-493-5p	HITS-CLIP	24374217
MIRT440964	hsa-miR-376c-3p	HITS-CLIP	24374217
MIRT487715	hsa-miR-4428	PAR-CLIP	23592263
MIRT487714	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT487713	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT487712	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT487711	hsa-miR-1321	PAR-CLIP	23592263
MIRT487710	hsa-miR-4739	PAR-CLIP	23592263
MIRT487709	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT487707	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT487708	hsa-miR-4419a	PAR-CLIP	23592263
MIRT487706	hsa-miR-4510	PAR-CLIP	23592263
MIRT487705	hsa-miR-6127	PAR-CLIP	23592263
MIRT487704	hsa-miR-6129	PAR-CLIP	23592263
MIRT487703	hsa-miR-6130	PAR-CLIP	23592263
MIRT487702	hsa-miR-6133	PAR-CLIP	23592263
MIRT487701	hsa-miR-4533	PAR-CLIP	23592263
MIRT487700	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT487699	hsa-miR-4306	PAR-CLIP	23592263
MIRT487698	hsa-miR-4644	PAR-CLIP	23592263
MIRT487697	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT487696	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT487695	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT487694	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT487693	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT487692	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT487690	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT487691	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT487689	hsa-miR-4271	PAR-CLIP	23592263
MIRT487688	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT487687	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT880400	hsa-miR-1193	CLIP-seq
MIRT880401	hsa-miR-1243	CLIP-seq
MIRT880402	hsa-miR-1324	CLIP-seq
MIRT880403	hsa-miR-2054	CLIP-seq
MIRT880404	hsa-miR-3148	CLIP-seq
MIRT880405	hsa-miR-3153	CLIP-seq
MIRT880406	hsa-miR-3168	CLIP-seq
MIRT880407	hsa-miR-3185	CLIP-seq
MIRT880408	hsa-miR-323-3p	CLIP-seq
MIRT880409	hsa-miR-329	CLIP-seq
MIRT880410	hsa-miR-3545-3p	CLIP-seq
MIRT880411	hsa-miR-362-3p	CLIP-seq
MIRT880412	hsa-miR-3688-3p	CLIP-seq
MIRT880413	hsa-miR-3915	CLIP-seq
MIRT880414	hsa-miR-3928	CLIP-seq
MIRT880415	hsa-miR-3941	CLIP-seq
MIRT880416	hsa-miR-3978	CLIP-seq
MIRT880417	hsa-miR-4311	CLIP-seq
MIRT880418	hsa-miR-432	CLIP-seq
MIRT880419	hsa-miR-4457	CLIP-seq
MIRT880420	hsa-miR-4648	CLIP-seq
MIRT880421	hsa-miR-4654	CLIP-seq
MIRT880422	hsa-miR-4668-5p	CLIP-seq
MIRT880423	hsa-miR-4724-5p	CLIP-seq
MIRT880424	hsa-miR-4769-5p	CLIP-seq
MIRT880425	hsa-miR-4789-5p	CLIP-seq
MIRT880426	hsa-miR-513b	CLIP-seq
MIRT880427	hsa-miR-576-3p	CLIP-seq
MIRT880428	hsa-miR-580	CLIP-seq
MIRT880429	hsa-miR-595	CLIP-seq
MIRT880430	hsa-miR-603	CLIP-seq
MIRT880431	hsa-miR-624	CLIP-seq
MIRT1556165	hsa-miR-3924	CLIP-seq
MIRT880401	hsa-miR-1243	CLIP-seq
MIRT880403	hsa-miR-2054	CLIP-seq
MIRT880410	hsa-miR-3545-3p	CLIP-seq
MIRT1960819	hsa-miR-369-3p	CLIP-seq
MIRT1960820	hsa-miR-374c	CLIP-seq
MIRT1960821	hsa-miR-520d-5p	CLIP-seq
MIRT1960822	hsa-miR-524-5p	CLIP-seq
MIRT1960823	hsa-miR-655	CLIP-seq
MIRT2197530	hsa-miR-129-3p	CLIP-seq
MIRT2197531	hsa-miR-22	CLIP-seq
MIRT880406	hsa-miR-3168	CLIP-seq
MIRT880407	hsa-miR-3185	CLIP-seq
MIRT880409	hsa-miR-329	CLIP-seq
MIRT2197532	hsa-miR-337-3p	CLIP-seq
MIRT2197533	hsa-miR-3606	CLIP-seq
MIRT2197534	hsa-miR-3620	CLIP-seq
MIRT880411	hsa-miR-362-3p	CLIP-seq
MIRT2197535	hsa-miR-3646	CLIP-seq
MIRT2197536	hsa-miR-3651	CLIP-seq
MIRT2197537	hsa-miR-371-5p	CLIP-seq
MIRT2197538	hsa-miR-371b-5p	CLIP-seq
MIRT1556165	hsa-miR-3924	CLIP-seq
MIRT2197539	hsa-miR-3925-3p	CLIP-seq
MIRT880415	hsa-miR-3941	CLIP-seq
MIRT2197540	hsa-miR-3944-5p	CLIP-seq
MIRT2197541	hsa-miR-3974	CLIP-seq
MIRT2197542	hsa-miR-410	CLIP-seq
MIRT2197543	hsa-miR-4270	CLIP-seq
MIRT2197544	hsa-miR-4441	CLIP-seq
MIRT2197545	hsa-miR-4687-5p	CLIP-seq
MIRT880425	hsa-miR-4789-5p	CLIP-seq
MIRT2197546	hsa-miR-491-3p	CLIP-seq
MIRT2197547	hsa-miR-513a-5p	CLIP-seq
MIRT2197548	hsa-miR-515-5p	CLIP-seq
MIRT2197549	hsa-miR-520a-5p	CLIP-seq
MIRT1960821	hsa-miR-520d-5p	CLIP-seq
MIRT1960822	hsa-miR-524-5p	CLIP-seq
MIRT2197550	hsa-miR-525-5p	CLIP-seq
MIRT2197551	hsa-miR-548a-3p	CLIP-seq
MIRT2197552	hsa-miR-548aa	CLIP-seq
MIRT2197553	hsa-miR-548e	CLIP-seq
MIRT2197554	hsa-miR-548f	CLIP-seq
MIRT2197555	hsa-miR-570	CLIP-seq
MIRT880430	hsa-miR-603	CLIP-seq
MIRT2197556	hsa-miR-618	CLIP-seq
MIRT2197557	hsa-miR-766	CLIP-seq
MIRT2197558	hsa-miR-921	CLIP-seq
MIRT2197559	hsa-miR-942	CLIP-seq
MIRT2385850	hsa-miR-1184	CLIP-seq
MIRT2385851	hsa-miR-1205	CLIP-seq
MIRT2385852	hsa-miR-1285	CLIP-seq
MIRT2385853	hsa-miR-3158-5p	CLIP-seq
MIRT2385854	hsa-miR-3187-5p	CLIP-seq
MIRT2197533	hsa-miR-3606	CLIP-seq
MIRT2385855	hsa-miR-3945	CLIP-seq
MIRT2385856	hsa-miR-4253	CLIP-seq
MIRT2385857	hsa-miR-544	CLIP-seq
MIRT2385858	hsa-miR-612	CLIP-seq
MIRT2197558	hsa-miR-921	CLIP-seq
MIRT2427256	hsa-miR-4490	CLIP-seq
MIRT2427257	hsa-miR-495	CLIP-seq
MIRT2427258	hsa-miR-582-3p	CLIP-seq
MIRT2500860	hsa-miR-101	CLIP-seq
MIRT2500861	hsa-miR-1237	CLIP-seq
MIRT2500862	hsa-miR-1248	CLIP-seq
MIRT2500863	hsa-miR-1278	CLIP-seq
MIRT2385852	hsa-miR-1285	CLIP-seq
MIRT2500864	hsa-miR-1290	CLIP-seq
MIRT2500865	hsa-miR-1293	CLIP-seq
MIRT2500866	hsa-miR-129-5p	CLIP-seq
MIRT2500867	hsa-miR-1299	CLIP-seq
MIRT2500868	hsa-miR-1323	CLIP-seq
MIRT880402	hsa-miR-1324	CLIP-seq
MIRT2500869	hsa-miR-145	CLIP-seq
MIRT2500870	hsa-miR-147	CLIP-seq
MIRT2500871	hsa-miR-1911	CLIP-seq
MIRT2500872	hsa-miR-217	CLIP-seq
MIRT2500873	hsa-miR-28-5p	CLIP-seq
MIRT2500874	hsa-miR-3074-5p	CLIP-seq
MIRT2500875	hsa-miR-31	CLIP-seq
MIRT2500876	hsa-miR-3115	CLIP-seq
MIRT2500877	hsa-miR-3125	CLIP-seq
MIRT2500878	hsa-miR-3127-3p	CLIP-seq
MIRT2500879	hsa-miR-3139	CLIP-seq
MIRT2500880	hsa-miR-3145-5p	CLIP-seq
MIRT880404	hsa-miR-3148	CLIP-seq
MIRT2500881	hsa-miR-3166	CLIP-seq
MIRT2500882	hsa-miR-3167	CLIP-seq
MIRT2385854	hsa-miR-3187-5p	CLIP-seq
MIRT2500883	hsa-miR-345	CLIP-seq
MIRT2500884	hsa-miR-3617	CLIP-seq
MIRT2197534	hsa-miR-3620	CLIP-seq
MIRT2500885	hsa-miR-3680	CLIP-seq
MIRT880412	hsa-miR-3688-3p	CLIP-seq
MIRT2500886	hsa-miR-3688-5p	CLIP-seq
MIRT1960819	hsa-miR-369-3p	CLIP-seq
MIRT2197538	hsa-miR-371b-5p	CLIP-seq
MIRT1960820	hsa-miR-374c	CLIP-seq
MIRT2500887	hsa-miR-3916	CLIP-seq
MIRT1556165	hsa-miR-3924	CLIP-seq
MIRT2385855	hsa-miR-3945	CLIP-seq
MIRT2385856	hsa-miR-4253	CLIP-seq
MIRT2500888	hsa-miR-4256	CLIP-seq
MIRT2500889	hsa-miR-4279	CLIP-seq
MIRT2500890	hsa-miR-4418	CLIP-seq
MIRT2500891	hsa-miR-4483	CLIP-seq
MIRT2427256	hsa-miR-4490	CLIP-seq
MIRT2500892	hsa-miR-4496	CLIP-seq
MIRT2500893	hsa-miR-4645-3p	CLIP-seq
MIRT2500894	hsa-miR-4663	CLIP-seq
MIRT2500895	hsa-miR-4678	CLIP-seq
MIRT2500896	hsa-miR-4731-3p	CLIP-seq
MIRT2500897	hsa-miR-4732-5p	CLIP-seq
MIRT2500898	hsa-miR-4762-3p	CLIP-seq
MIRT2500899	hsa-miR-4768-5p	CLIP-seq
MIRT2500900	hsa-miR-4782-5p	CLIP-seq
MIRT2500901	hsa-miR-4795-3p	CLIP-seq
MIRT2500902	hsa-miR-4801	CLIP-seq
MIRT2500903	hsa-miR-486-5p	CLIP-seq
MIRT2427257	hsa-miR-495	CLIP-seq
MIRT2500904	hsa-miR-498	CLIP-seq
MIRT2500905	hsa-miR-508-5p	CLIP-seq
MIRT2500906	hsa-miR-509-3-5p	CLIP-seq
MIRT2500907	hsa-miR-509-5p	CLIP-seq
MIRT2500908	hsa-miR-516b	CLIP-seq
MIRT2500909	hsa-miR-548m	CLIP-seq
MIRT2500910	hsa-miR-548o	CLIP-seq
MIRT2500911	hsa-miR-561	CLIP-seq
MIRT880427	hsa-miR-576-3p	CLIP-seq
MIRT2427258	hsa-miR-582-3p	CLIP-seq
MIRT2500912	hsa-miR-587	CLIP-seq
MIRT2500913	hsa-miR-599	CLIP-seq
MIRT2385858	hsa-miR-612	CLIP-seq
MIRT2500914	hsa-miR-628-5p	CLIP-seq
MIRT2500915	hsa-miR-641	CLIP-seq
MIRT2500916	hsa-miR-642b	CLIP-seq
MIRT2500917	hsa-miR-651	CLIP-seq
MIRT1960823	hsa-miR-655	CLIP-seq
MIRT2500918	hsa-miR-708	CLIP-seq
MIRT2500919	hsa-miR-876-5p	CLIP-seq
MIRT2500920	hsa-miR-877	CLIP-seq
MIRT2500921	hsa-miR-885-5p	CLIP-seq
MIRT2500922	hsa-miR-888	CLIP-seq
MIRT2500860	hsa-miR-101	CLIP-seq
MIRT2500861	hsa-miR-1237	CLIP-seq
MIRT2500862	hsa-miR-1248	CLIP-seq
MIRT2677874	hsa-miR-1254	CLIP-seq
MIRT2500863	hsa-miR-1278	CLIP-seq
MIRT2677875	hsa-miR-1279	CLIP-seq
MIRT2500866	hsa-miR-129-5p	CLIP-seq
MIRT2500867	hsa-miR-1299	CLIP-seq
MIRT880402	hsa-miR-1324	CLIP-seq
MIRT2500869	hsa-miR-145	CLIP-seq
MIRT2500871	hsa-miR-1911	CLIP-seq
MIRT2677876	hsa-miR-1913	CLIP-seq
MIRT2500872	hsa-miR-217	CLIP-seq
MIRT2677877	hsa-miR-23a	CLIP-seq
MIRT2677878	hsa-miR-23b	CLIP-seq
MIRT2677879	hsa-miR-23c	CLIP-seq
MIRT2677880	hsa-miR-3116	CLIP-seq
MIRT2500881	hsa-miR-3166	CLIP-seq
MIRT2677881	hsa-miR-3189-5p	CLIP-seq
MIRT2677882	hsa-miR-3192	CLIP-seq
MIRT2677883	hsa-miR-324-3p	CLIP-seq
MIRT2500883	hsa-miR-345	CLIP-seq
MIRT2500884	hsa-miR-3617	CLIP-seq
MIRT2197534	hsa-miR-3620	CLIP-seq
MIRT2500885	hsa-miR-3680	CLIP-seq
MIRT2677884	hsa-miR-3689d	CLIP-seq
MIRT1960819	hsa-miR-369-3p	CLIP-seq
MIRT1960820	hsa-miR-374c	CLIP-seq
MIRT2677885	hsa-miR-3907	CLIP-seq
MIRT1556165	hsa-miR-3924	CLIP-seq
MIRT2677886	hsa-miR-4254	CLIP-seq
MIRT2500888	hsa-miR-4256	CLIP-seq
MIRT2677887	hsa-miR-4268	CLIP-seq
MIRT2677888	hsa-miR-4286	CLIP-seq
MIRT2677889	hsa-miR-4300	CLIP-seq
MIRT2500890	hsa-miR-4418	CLIP-seq
MIRT2677890	hsa-miR-4448	CLIP-seq
MIRT2427256	hsa-miR-4490	CLIP-seq
MIRT2500892	hsa-miR-4496	CLIP-seq
MIRT2500893	hsa-miR-4645-3p	CLIP-seq
MIRT2500894	hsa-miR-4663	CLIP-seq
MIRT2500896	hsa-miR-4731-3p	CLIP-seq
MIRT2677891	hsa-miR-4758-3p	CLIP-seq
MIRT2500898	hsa-miR-4762-3p	CLIP-seq
MIRT2677892	hsa-miR-4763-5p	CLIP-seq
MIRT2500899	hsa-miR-4768-5p	CLIP-seq
MIRT2500900	hsa-miR-4782-5p	CLIP-seq
MIRT2500902	hsa-miR-4801	CLIP-seq
MIRT2427257	hsa-miR-495	CLIP-seq
MIRT2500904	hsa-miR-498	CLIP-seq
MIRT2500906	hsa-miR-509-3-5p	CLIP-seq
MIRT2500907	hsa-miR-509-5p	CLIP-seq
MIRT2677893	hsa-miR-5096	CLIP-seq
MIRT2500908	hsa-miR-516b	CLIP-seq
MIRT2500911	hsa-miR-561	CLIP-seq
MIRT2427258	hsa-miR-582-3p	CLIP-seq
MIRT2500914	hsa-miR-628-5p	CLIP-seq
MIRT2500915	hsa-miR-641	CLIP-seq
MIRT2500916	hsa-miR-642b	CLIP-seq
MIRT2500917	hsa-miR-651	CLIP-seq
MIRT1960823	hsa-miR-655	CLIP-seq
MIRT2500921	hsa-miR-885-5p	CLIP-seq
MIRT2677894	hsa-miR-920	CLIP-seq

Show/Hide all (34)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000086	Process	G2/M transition of mitotic cell cycle	IDA	20059949
GO:0000166	Function	Nucleotide binding	IEA
GO:0000307	Component	Cyclin-dependent protein kinase holoenzyme complex	IEA
GO:0000307	Component	Cyclin-dependent protein kinase holoenzyme complex	IPI	19524571
GO:0000308	Component	Cytoplasmic cyclin-dependent protein kinase holoenzyme complex	IDA	19524571, 20059949
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004693	Function	Cyclin-dependent protein serine/threonine kinase activity	IBA
GO:0004693	Function	Cyclin-dependent protein serine/threonine kinase activity	IEA
GO:0004693	Function	Cyclin-dependent protein serine/threonine kinase activity	IMP	19524571, 20059949
GO:0005515	Function	Protein binding	IPI	16775625, 17517622, 19524571, 22939624, 23602568, 28514442, 33961781, 36931259
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	9202329
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	9202329
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	IEA
GO:0005886	Component	Plasma membrane	IDA	19524571, 20059949
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030332	Function	Cyclin binding	IBA
GO:0030332	Function	Cyclin binding	IPI	19524571, 20059949
GO:0051301	Process	Cell division	IEA
GO:0060828	Process	Regulation of canonical Wnt signaling pathway	IDA	20059949
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1901987	Process	Regulation of cell cycle phase transition	IBA

MIM	HGNC	e!Ensembl
610679	8883	ENSG00000058091

O94921

Protein name

Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)

Protein function

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylatio

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	135 → 419	Protein kinase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Also detected at lower levels in other tissues except in spleen and thymus where expression is barely detected. {ECO:0000269|PubMed:11313143}.

Sequence

MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSS
PSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIR
EASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQL
LRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPP
DVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGV
HSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFS
DLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH

Sequence length

469

Interactions

View interactions

	KEGG
	Transcriptional misregulation in cancer

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, HEPATOCELLULAR	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLOMERULONEPHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEPATOCELLULAR CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RETINOPATHY OF PREMATURITY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (44)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	30474270, 30915884		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	26033031, 28300591, 29193658		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	26488471	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	26488471	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	30915884, 33635431	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	26406598	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	26772918, 27505004, 30557834		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	27458094		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	28498444		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	27458094, 32737302	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Common Variable Immunodeficiency	Common Variable Immunodeficiency	GWASDB_DG	21497890		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Disease	Coronary artery disease	Pubtator	21829389	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	26772918		★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	26488471		★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	22333595	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophagus Neoplasm	BEFREE	26488471		★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	22333595	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	26234562, 28498444, 29289838		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	17559150, 21184254, 21577206, 26488471, 28498444, 29863248, 30488589		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	CTD_human_DG	22922871		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	GWASCAT_DG	29246937		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	26033031, 28300591, 29193658		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	26488471		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	26772918, 27505004, 30557834		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	26823712, 30058687, 30474270, 30915884		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	30185212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	28498444		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28498444, 30474270		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	27458094		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma Cutaneous Malignant	Melanoma	Pubtator	31673075	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	17559150, 21577206, 22333595, 26033031, 26234562, 26488471, 26772918, 26823712, 27458094, 28498444, 29193658, 30185212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	27458099, 27666310, 29630731		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	35723551	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	29022909, 29944887, 30119217		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Mucinous Adenocarcinoma	Ovarian adenocarcinoma	UNIPROT_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	26772918, 27505004, 30557834		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	26823712, 30058687, 30474270, 30915884		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	26823712, 30058687, 30915884	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	30185212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	34889941	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	22333595		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	26488471	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Thyroid Cancer Papillary	Papillary thyroid cancer	Pubtator	32602632	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

CDK14 (cyclin dependent kinase 14)