TM7SF3 (transmembrane 7 superfamily member 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51768 |
| Gene name | Transmembrane 7 superfamily member 3 |
| Gene symbol | TM7SF3 |
| Synonyms (NCBI Gene) |
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| Chromosome | 12 |
| Chromosome location | 12p11.23 |
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miRNA
miRNA information provided by mirtarbase database.
404
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NS93 | ||||||||||
| Protein name | Transmembrane 7 superfamily member 3 (Seven span transmembrane protein) | ||||||||||
| Protein function | Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells (PubMed:21853325). Is a downstream transcriptional target of p53/TP53, and acts as a pro-sur | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. Highly expressed in kidney and pancreas. {ECO:0000269|PubMed:10828615}. | ||||||||||
| Sequence |
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| Sequence length | 570 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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