LUC7L3 (LUC7 like 3 pre-mRNA splicing factor)

Gene

• Entrez ID: 51747
• Gene name: LUC7 like 3 pre-mRNA splicing factor
• Gene symbol: LUC7L3
• Synonyms (NCBI Gene): CRA, CREAP-1, CROP, LUC7A, OA48-18, hLuc7A
• Chromosome: 17
• Chromosome location: 17q21.33
• Summary: This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020883	hsa-miR-155-5p	Proteomics	18668040
MIRT045993	hsa-miR-125b-5p	CLASH	23622248
MIRT041706	hsa-miR-484	CLASH	23622248
MIRT040591	hsa-miR-92b-3p	CLASH	23622248
MIRT449190	hsa-miR-15a-5p	PAR-CLIP	22100165
MIRT449189	hsa-miR-15b-5p	PAR-CLIP	22100165
MIRT449188	hsa-miR-16-5p	PAR-CLIP	22100165
MIRT449187	hsa-miR-195-5p	PAR-CLIP	22100165
MIRT449186	hsa-miR-424-5p	PAR-CLIP	22100165
MIRT449185	hsa-miR-497-5p	PAR-CLIP	22100165
MIRT449184	hsa-miR-6838-5p	PAR-CLIP	22100165
MIRT449183	hsa-miR-1265	PAR-CLIP	22100165
MIRT449182	hsa-miR-6847-5p	PAR-CLIP	22100165
MIRT288020	hsa-miR-4468	PAR-CLIP	22100165
MIRT449181	hsa-miR-3150b-3p	PAR-CLIP	22100165
MIRT449180	hsa-miR-4784	PAR-CLIP	22100165
MIRT449179	hsa-miR-3605-5p	PAR-CLIP	22100165
MIRT449178	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT449177	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT449190	hsa-miR-15a-5p	PAR-CLIP	22100165
MIRT449189	hsa-miR-15b-5p	PAR-CLIP	22100165
MIRT449188	hsa-miR-16-5p	PAR-CLIP	22100165
MIRT449187	hsa-miR-195-5p	PAR-CLIP	22100165
MIRT449186	hsa-miR-424-5p	PAR-CLIP	22100165
MIRT449185	hsa-miR-497-5p	PAR-CLIP	22100165
MIRT449184	hsa-miR-6838-5p	PAR-CLIP	22100165
MIRT449183	hsa-miR-1265	PAR-CLIP	22100165
MIRT449182	hsa-miR-6847-5p	PAR-CLIP	22100165
MIRT288020	hsa-miR-4468	PAR-CLIP	22100165
MIRT449181	hsa-miR-3150b-3p	PAR-CLIP	22100165
MIRT449180	hsa-miR-4784	PAR-CLIP	22100165
MIRT449179	hsa-miR-3605-5p	PAR-CLIP	22100165
MIRT449178	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT449177	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT1122369	hsa-miR-1264	CLIP-seq
MIRT1122370	hsa-miR-1305	CLIP-seq
MIRT1122371	hsa-miR-141	CLIP-seq
MIRT1122372	hsa-miR-200a	CLIP-seq
MIRT1122373	hsa-miR-2278	CLIP-seq
MIRT1122374	hsa-miR-3160-5p	CLIP-seq
MIRT1122375	hsa-miR-3682-5p	CLIP-seq
MIRT1122376	hsa-miR-3973	CLIP-seq
MIRT1122377	hsa-miR-4252	CLIP-seq
MIRT1122378	hsa-miR-4276	CLIP-seq
MIRT1122379	hsa-miR-4643	CLIP-seq
MIRT1122380	hsa-miR-4700-3p	CLIP-seq
MIRT1122381	hsa-miR-4732-5p	CLIP-seq
MIRT1122382	hsa-miR-4766-5p	CLIP-seq
MIRT1122383	hsa-miR-4799-5p	CLIP-seq
MIRT1122384	hsa-miR-500a	CLIP-seq
MIRT1122385	hsa-miR-520g	CLIP-seq
MIRT1122386	hsa-miR-520h	CLIP-seq
MIRT1122387	hsa-miR-548c-3p	CLIP-seq
MIRT1122388	hsa-miR-562	CLIP-seq
MIRT1122389	hsa-miR-570	CLIP-seq
MIRT1122390	hsa-miR-605	CLIP-seq
MIRT1122391	hsa-miR-607	CLIP-seq
MIRT1122392	hsa-miR-149	CLIP-seq
MIRT1122393	hsa-miR-193a-3p	CLIP-seq
MIRT1122394	hsa-miR-193b	CLIP-seq
MIRT1122395	hsa-miR-194	CLIP-seq
MIRT1122373	hsa-miR-2278	CLIP-seq
MIRT1122396	hsa-miR-3119	CLIP-seq
MIRT1122397	hsa-miR-3136-5p	CLIP-seq
MIRT1122398	hsa-miR-3591-3p	CLIP-seq
MIRT1122399	hsa-miR-3613-3p	CLIP-seq
MIRT1122400	hsa-miR-362-5p	CLIP-seq
MIRT1122401	hsa-miR-3919	CLIP-seq
MIRT1122377	hsa-miR-4252	CLIP-seq
MIRT1122402	hsa-miR-4274	CLIP-seq
MIRT1122378	hsa-miR-4276	CLIP-seq
MIRT1122403	hsa-miR-4439	CLIP-seq
MIRT1122404	hsa-miR-4444	CLIP-seq
MIRT1122405	hsa-miR-4513	CLIP-seq
MIRT1122406	hsa-miR-4519	CLIP-seq
MIRT1122407	hsa-miR-4638-5p	CLIP-seq
MIRT1122379	hsa-miR-4643	CLIP-seq
MIRT1122408	hsa-miR-4661-5p	CLIP-seq
MIRT1122409	hsa-miR-4708-3p	CLIP-seq
MIRT1122410	hsa-miR-4709-5p	CLIP-seq
MIRT1122411	hsa-miR-4731-3p	CLIP-seq
MIRT1122381	hsa-miR-4732-5p	CLIP-seq
MIRT1122412	hsa-miR-4756-3p	CLIP-seq
MIRT1122413	hsa-miR-4760-3p	CLIP-seq
MIRT1122414	hsa-miR-4775	CLIP-seq
MIRT1122415	hsa-miR-4778-3p	CLIP-seq
MIRT1122416	hsa-miR-4801	CLIP-seq
MIRT1122384	hsa-miR-500a	CLIP-seq
MIRT1122417	hsa-miR-500b	CLIP-seq
MIRT1122418	hsa-miR-516a-5p	CLIP-seq
MIRT1122419	hsa-miR-548ae	CLIP-seq
MIRT1122420	hsa-miR-548aj	CLIP-seq
MIRT1122421	hsa-miR-548am	CLIP-seq
MIRT1122422	hsa-miR-548p	CLIP-seq
MIRT1122423	hsa-miR-548x	CLIP-seq
MIRT1122424	hsa-miR-550b	CLIP-seq
MIRT1122388	hsa-miR-562	CLIP-seq
MIRT1122425	hsa-miR-654-3p	CLIP-seq
MIRT1122426	hsa-miR-760	CLIP-seq
MIRT1122427	hsa-miR-892b	CLIP-seq
MIRT1122428	hsa-miR-943	CLIP-seq
MIRT737761	hsa-miR-3120-5p	CLIP-seq
MIRT737760	hsa-miR-3200-5p	CLIP-seq
MIRT737758	hsa-miR-361-5p	CLIP-seq
MIRT737759	hsa-miR-4649-3p	CLIP-seq
MIRT2034573	hsa-miR-1257	CLIP-seq
MIRT1122370	hsa-miR-1305	CLIP-seq
MIRT2034574	hsa-miR-186	CLIP-seq
MIRT2034575	hsa-miR-297	CLIP-seq
MIRT1122396	hsa-miR-3119	CLIP-seq
MIRT737761	hsa-miR-3120-5p	CLIP-seq
MIRT2034576	hsa-miR-3133	CLIP-seq
MIRT2034577	hsa-miR-3140-3p	CLIP-seq
MIRT2034578	hsa-miR-3149	CLIP-seq
MIRT1122374	hsa-miR-3160-5p	CLIP-seq
MIRT2034579	hsa-miR-3188	CLIP-seq
MIRT737760	hsa-miR-3200-5p	CLIP-seq
MIRT737758	hsa-miR-361-5p	CLIP-seq
MIRT2034580	hsa-miR-377	CLIP-seq
MIRT2034581	hsa-miR-412	CLIP-seq
MIRT737759	hsa-miR-4649-3p	CLIP-seq
MIRT2034582	hsa-miR-4793-3p	CLIP-seq
MIRT1122384	hsa-miR-500a	CLIP-seq
MIRT2034583	hsa-miR-5096	CLIP-seq
MIRT2034584	hsa-miR-567	CLIP-seq
MIRT1122390	hsa-miR-605	CLIP-seq
MIRT2034585	hsa-miR-630	CLIP-seq
MIRT1122425	hsa-miR-654-3p	CLIP-seq
MIRT2265056	hsa-miR-1	CLIP-seq
MIRT2265057	hsa-miR-1179	CLIP-seq
MIRT2034573	hsa-miR-1257	CLIP-seq
MIRT2265058	hsa-miR-1263	CLIP-seq
MIRT2265059	hsa-miR-1273	CLIP-seq
MIRT2265060	hsa-miR-1273g	CLIP-seq
MIRT2265061	hsa-miR-1283	CLIP-seq
MIRT1122370	hsa-miR-1305	CLIP-seq
MIRT2265062	hsa-miR-130a	CLIP-seq
MIRT2265063	hsa-miR-130b	CLIP-seq
MIRT1122371	hsa-miR-141	CLIP-seq
MIRT1122392	hsa-miR-149	CLIP-seq
MIRT2265064	hsa-miR-1910	CLIP-seq
MIRT2265065	hsa-miR-1911	CLIP-seq
MIRT1122393	hsa-miR-193a-3p	CLIP-seq
MIRT1122394	hsa-miR-193b	CLIP-seq
MIRT1122395	hsa-miR-194	CLIP-seq
MIRT1122372	hsa-miR-200a	CLIP-seq
MIRT2265066	hsa-miR-206	CLIP-seq
MIRT2265067	hsa-miR-2116	CLIP-seq
MIRT2265068	hsa-miR-221	CLIP-seq
MIRT2265069	hsa-miR-222	CLIP-seq
MIRT1122373	hsa-miR-2278	CLIP-seq
MIRT2265070	hsa-miR-2964a-3p	CLIP-seq
MIRT2034575	hsa-miR-297	CLIP-seq
MIRT2265071	hsa-miR-299-3p	CLIP-seq
MIRT2265072	hsa-miR-301a	CLIP-seq
MIRT2265073	hsa-miR-301b	CLIP-seq
MIRT2265074	hsa-miR-3065-5p	CLIP-seq
MIRT1122396	hsa-miR-3119	CLIP-seq
MIRT737761	hsa-miR-3120-5p	CLIP-seq
MIRT2265075	hsa-miR-3123	CLIP-seq
MIRT2265076	hsa-miR-3129-3p	CLIP-seq
MIRT2265077	hsa-miR-3132	CLIP-seq
MIRT2265078	hsa-miR-3140-5p	CLIP-seq
MIRT2265079	hsa-miR-3143	CLIP-seq
MIRT2034578	hsa-miR-3149	CLIP-seq
MIRT2265080	hsa-miR-3156-3p	CLIP-seq
MIRT2265081	hsa-miR-3157-5p	CLIP-seq
MIRT2265082	hsa-miR-3174	CLIP-seq
MIRT2265083	hsa-miR-3177-5p	CLIP-seq
MIRT737760	hsa-miR-3200-5p	CLIP-seq
MIRT2265084	hsa-miR-33a	CLIP-seq
MIRT2265085	hsa-miR-33b	CLIP-seq
MIRT737758	hsa-miR-361-5p	CLIP-seq
MIRT2265086	hsa-miR-3622b-5p	CLIP-seq
MIRT2265087	hsa-miR-3646	CLIP-seq
MIRT2265088	hsa-miR-3659	CLIP-seq
MIRT2265089	hsa-miR-3662	CLIP-seq
MIRT2265090	hsa-miR-3666	CLIP-seq
MIRT2265091	hsa-miR-3673	CLIP-seq
MIRT1122375	hsa-miR-3682-5p	CLIP-seq
MIRT2034580	hsa-miR-377	CLIP-seq
MIRT2265092	hsa-miR-3920	CLIP-seq
MIRT2265093	hsa-miR-3925-5p	CLIP-seq
MIRT1122376	hsa-miR-3973	CLIP-seq
MIRT1122377	hsa-miR-4252	CLIP-seq
MIRT2265094	hsa-miR-4265	CLIP-seq
MIRT1122402	hsa-miR-4274	CLIP-seq
MIRT2265095	hsa-miR-4277	CLIP-seq
MIRT2265096	hsa-miR-4295	CLIP-seq
MIRT2265097	hsa-miR-4296	CLIP-seq
MIRT2265098	hsa-miR-4301	CLIP-seq
MIRT2265099	hsa-miR-4302	CLIP-seq
MIRT2265100	hsa-miR-4322	CLIP-seq
MIRT2265101	hsa-miR-4417	CLIP-seq
MIRT2265102	hsa-miR-4426	CLIP-seq
MIRT1122404	hsa-miR-4444	CLIP-seq
MIRT2265103	hsa-miR-4451	CLIP-seq
MIRT2265104	hsa-miR-4474-5p	CLIP-seq
MIRT2265105	hsa-miR-4477a	CLIP-seq
MIRT2265106	hsa-miR-4488	CLIP-seq
MIRT2265107	hsa-miR-4490	CLIP-seq
MIRT2265108	hsa-miR-4496	CLIP-seq
MIRT2265109	hsa-miR-4503	CLIP-seq
MIRT2265110	hsa-miR-4506	CLIP-seq
MIRT2265111	hsa-miR-4517	CLIP-seq
MIRT1122406	hsa-miR-4519	CLIP-seq
MIRT2265112	hsa-miR-454	CLIP-seq
MIRT2265113	hsa-miR-455-3p	CLIP-seq
MIRT2265114	hsa-miR-455-5p	CLIP-seq
MIRT2265115	hsa-miR-4637	CLIP-seq
MIRT1122407	hsa-miR-4638-5p	CLIP-seq
MIRT1122379	hsa-miR-4643	CLIP-seq
MIRT2265116	hsa-miR-4647	CLIP-seq
MIRT737759	hsa-miR-4649-3p	CLIP-seq
MIRT2265117	hsa-miR-4649-5p	CLIP-seq
MIRT2265118	hsa-miR-4658	CLIP-seq
MIRT2265119	hsa-miR-4662b	CLIP-seq
MIRT2265120	hsa-miR-4671-3p	CLIP-seq
MIRT2265121	hsa-miR-4672	CLIP-seq
MIRT2265122	hsa-miR-4676-5p	CLIP-seq
MIRT2265123	hsa-miR-4680-3p	CLIP-seq
MIRT2265124	hsa-miR-4691-3p	CLIP-seq
MIRT2265125	hsa-miR-4697-5p	CLIP-seq
MIRT1122410	hsa-miR-4709-5p	CLIP-seq
MIRT2265126	hsa-miR-4711-5p	CLIP-seq
MIRT2265127	hsa-miR-4715-3p	CLIP-seq
MIRT2265128	hsa-miR-4719	CLIP-seq
MIRT2265129	hsa-miR-4720-5p	CLIP-seq
MIRT2265130	hsa-miR-4727-5p	CLIP-seq
MIRT1122411	hsa-miR-4731-3p	CLIP-seq
MIRT1122381	hsa-miR-4732-5p	CLIP-seq
MIRT2265131	hsa-miR-4758-5p	CLIP-seq
MIRT2265132	hsa-miR-4764-5p	CLIP-seq
MIRT2265133	hsa-miR-4765	CLIP-seq
MIRT1122382	hsa-miR-4766-5p	CLIP-seq
MIRT2265134	hsa-miR-4769-3p	CLIP-seq
MIRT2265135	hsa-miR-4774-5p	CLIP-seq
MIRT2034582	hsa-miR-4793-3p	CLIP-seq
MIRT2265136	hsa-miR-4799-3p	CLIP-seq
MIRT1122383	hsa-miR-4799-5p	CLIP-seq
MIRT1122416	hsa-miR-4801	CLIP-seq
MIRT2265137	hsa-miR-4802-3p	CLIP-seq
MIRT2265138	hsa-miR-490-5p	CLIP-seq
MIRT2265139	hsa-miR-493	CLIP-seq
MIRT2265140	hsa-miR-495	CLIP-seq
MIRT2265141	hsa-miR-502-5p	CLIP-seq
MIRT2034583	hsa-miR-5096	CLIP-seq
MIRT2265142	hsa-miR-513b	CLIP-seq
MIRT1122418	hsa-miR-516a-5p	CLIP-seq
MIRT2265143	hsa-miR-548ac	CLIP-seq
MIRT1122419	hsa-miR-548ae	CLIP-seq
MIRT1122420	hsa-miR-548aj	CLIP-seq
MIRT1122421	hsa-miR-548am	CLIP-seq
MIRT1122387	hsa-miR-548c-3p	CLIP-seq
MIRT2265144	hsa-miR-548d-3p	CLIP-seq
MIRT2265145	hsa-miR-548v	CLIP-seq
MIRT1122423	hsa-miR-548x	CLIP-seq
MIRT2265146	hsa-miR-548z	CLIP-seq
MIRT2265147	hsa-miR-550a	CLIP-seq
MIRT1122388	hsa-miR-562	CLIP-seq
MIRT2034584	hsa-miR-567	CLIP-seq
MIRT2265148	hsa-miR-574-5p	CLIP-seq
MIRT2265149	hsa-miR-575	CLIP-seq
MIRT2265150	hsa-miR-580	CLIP-seq
MIRT2265151	hsa-miR-593	CLIP-seq
MIRT1122390	hsa-miR-605	CLIP-seq
MIRT2265152	hsa-miR-613	CLIP-seq
MIRT2265153	hsa-miR-619	CLIP-seq
MIRT2034585	hsa-miR-630	CLIP-seq
MIRT2265154	hsa-miR-643	CLIP-seq
MIRT1122425	hsa-miR-654-3p	CLIP-seq
MIRT2265155	hsa-miR-656	CLIP-seq
MIRT1122426	hsa-miR-760	CLIP-seq
MIRT2265156	hsa-miR-875-5p	CLIP-seq
MIRT1122427	hsa-miR-892b	CLIP-seq
MIRT2265157	hsa-miR-944	CLIP-seq
MIRT1122396	hsa-miR-3119	CLIP-seq
MIRT737761	hsa-miR-3120-5p	CLIP-seq
MIRT2265080	hsa-miR-3156-3p	CLIP-seq
MIRT737760	hsa-miR-3200-5p	CLIP-seq
MIRT737758	hsa-miR-361-5p	CLIP-seq
MIRT2265087	hsa-miR-3646	CLIP-seq
MIRT2265089	hsa-miR-3662	CLIP-seq
MIRT2265092	hsa-miR-3920	CLIP-seq
MIRT2265098	hsa-miR-4301	CLIP-seq
MIRT2265104	hsa-miR-4474-5p	CLIP-seq
MIRT737759	hsa-miR-4649-3p	CLIP-seq
MIRT1122387	hsa-miR-548c-3p	CLIP-seq
MIRT1122390	hsa-miR-605	CLIP-seq
MIRT1122369	hsa-miR-1264	CLIP-seq
MIRT1122370	hsa-miR-1305	CLIP-seq
MIRT1122371	hsa-miR-141	CLIP-seq
MIRT2034574	hsa-miR-186	CLIP-seq
MIRT1122395	hsa-miR-194	CLIP-seq
MIRT1122372	hsa-miR-200a	CLIP-seq
MIRT2034576	hsa-miR-3133	CLIP-seq
MIRT1122374	hsa-miR-3160-5p	CLIP-seq
MIRT1122401	hsa-miR-3919	CLIP-seq
MIRT1122376	hsa-miR-3973	CLIP-seq
MIRT2034581	hsa-miR-412	CLIP-seq
MIRT1122377	hsa-miR-4252	CLIP-seq
MIRT2564131	hsa-miR-4264	CLIP-seq
MIRT1122378	hsa-miR-4276	CLIP-seq
MIRT2564132	hsa-miR-4633-5p	CLIP-seq
MIRT2265115	hsa-miR-4637	CLIP-seq
MIRT1122380	hsa-miR-4700-3p	CLIP-seq
MIRT1122412	hsa-miR-4756-3p	CLIP-seq
MIRT2564133	hsa-miR-4797-3p	CLIP-seq
MIRT2564134	hsa-miR-491-3p	CLIP-seq
MIRT1122384	hsa-miR-500a	CLIP-seq
MIRT2034583	hsa-miR-5096	CLIP-seq
MIRT1122385	hsa-miR-520g	CLIP-seq
MIRT1122386	hsa-miR-520h	CLIP-seq
MIRT1122387	hsa-miR-548c-3p	CLIP-seq
MIRT2564135	hsa-miR-548l	CLIP-seq
MIRT2564136	hsa-miR-548n	CLIP-seq
MIRT1122389	hsa-miR-570	CLIP-seq
MIRT1122391	hsa-miR-607	CLIP-seq
MIRT2034585	hsa-miR-630	CLIP-seq
MIRT1122395	hsa-miR-194	CLIP-seq
MIRT1122396	hsa-miR-3119	CLIP-seq
MIRT1122374	hsa-miR-3160-5p	CLIP-seq
MIRT2265140	hsa-miR-495	CLIP-seq
MIRT1122384	hsa-miR-500a	CLIP-seq
MIRT1122419	hsa-miR-548ae	CLIP-seq
MIRT1122420	hsa-miR-548aj	CLIP-seq
MIRT1122421	hsa-miR-548am	CLIP-seq
MIRT1122423	hsa-miR-548x	CLIP-seq
MIRT1122369	hsa-miR-1264	CLIP-seq
MIRT1122370	hsa-miR-1305	CLIP-seq
MIRT1122371	hsa-miR-141	CLIP-seq
MIRT2034574	hsa-miR-186	CLIP-seq
MIRT2684291	hsa-miR-199a-3p	CLIP-seq
MIRT2684292	hsa-miR-199b-3p	CLIP-seq
MIRT1122372	hsa-miR-200a	CLIP-seq
MIRT2684293	hsa-miR-3129-5p	CLIP-seq
MIRT2034576	hsa-miR-3133	CLIP-seq
MIRT1122374	hsa-miR-3160-5p	CLIP-seq
MIRT2684294	hsa-miR-3909	CLIP-seq
MIRT1122376	hsa-miR-3973	CLIP-seq
MIRT2034581	hsa-miR-412	CLIP-seq
MIRT1122377	hsa-miR-4252	CLIP-seq
MIRT2564131	hsa-miR-4264	CLIP-seq
MIRT1122378	hsa-miR-4276	CLIP-seq
MIRT2684295	hsa-miR-4540	CLIP-seq
MIRT2564132	hsa-miR-4633-5p	CLIP-seq
MIRT2265115	hsa-miR-4637	CLIP-seq
MIRT1122380	hsa-miR-4700-3p	CLIP-seq
MIRT2564133	hsa-miR-4797-3p	CLIP-seq
MIRT2564134	hsa-miR-491-3p	CLIP-seq
MIRT1122384	hsa-miR-500a	CLIP-seq
MIRT2034583	hsa-miR-5096	CLIP-seq
MIRT1122385	hsa-miR-520g	CLIP-seq
MIRT1122386	hsa-miR-520h	CLIP-seq
MIRT1122387	hsa-miR-548c-3p	CLIP-seq
MIRT2564135	hsa-miR-548l	CLIP-seq
MIRT2564136	hsa-miR-548n	CLIP-seq
MIRT1122389	hsa-miR-570	CLIP-seq
MIRT1122391	hsa-miR-607	CLIP-seq
MIRT2034585	hsa-miR-630	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003729	Function	MRNA binding	IBA
GO:0003729	Function	MRNA binding	IEA
GO:0003729	Function	MRNA binding	IMP	10631324
GO:0005515	Function	Protein binding	IPI	15798186, 18663000, 19574390, 32296183
GO:0005634	Component	Nucleus	IDA	12565863
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005685	Component	U1 snRNP	IBA
GO:0005685	Component	U1 snRNP	IEA
GO:0006376	Process	MRNA splice site recognition	IBA
GO:0006376	Process	MRNA splice site recognition	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0008380	Process	RNA splicing	IMP	10631324
GO:0016607	Component	Nuclear speck	IDA
GO:0016607	Component	Nuclear speck	IEA
GO:0071004	Component	U2-type prespliceosome	IBA

Other IDs

• MIM: 609434
• HGNC: 24309
• e!Ensembl: ENSG00000108848

Protein

• UniProt ID: O95232
• Protein name: Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)
• Protein function: Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03194	LUC7	3 → 295	LUC7 N_terminus	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in
• Sequence:

  MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEK
  IHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAG
  PTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIE
  SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEE
  PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS
  SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS
  YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS
  EDIKSEGDTQSN

• Sequence length: 432

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC KIDNEY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIGESTIVE SYSTEM INFECTIOUS DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenoma of large intestine	Colorectal adenoma	BEFREE	30791768		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	32497068	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	24899691	Associate	★☆☆☆☆ Found in Text Mining only
Cheilitis	Cheilitis	BEFREE	28786105		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	31384612		★☆☆☆☆ Found in Text Mining only
Congenital chromosomal disease	Congenital Chromosomal Disease	BEFREE	3514807		★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	21859973, 22939879		★☆☆☆☆ Found in Text Mining only
Head and Neck Carcinoma	Head And Neck Carcinoma	BEFREE	22986368		★☆☆☆☆ Found in Text Mining only
Head and Neck Neoplasms	Head and neck neoplasm	Pubtator	22986368	Associate	★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	BEFREE	21859973, 22939879		★☆☆☆☆ Found in Text Mining only
Heart Failure	Heart failure	Pubtator	21859973, 22939879	Associate	★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	BEFREE	29325917		★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	22939879	Stimulate	★☆☆☆☆ Found in Text Mining only
Kidney Failure, Chronic	Kidney Failure	GWASCAT_DG	31178898		★☆☆☆☆ Found in Text Mining only
Macular Edema, Cystoid	Cystoid macular edema	BEFREE	30347030		★☆☆☆☆ Found in Text Mining only
Macular retinal edema	Macular edema	BEFREE	30347030		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28506699, 30791768		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	29176719		★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	22986368		★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	22986368	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	16891455, 28786105		★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	29803928, 30791768		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	29079785, 30274272		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	37143720	Associate	★☆☆☆☆ Found in Text Mining only
Rhabdomyosarcoma	Rhabdomyosarcoma	BEFREE	24467821		★☆☆☆☆ Found in Text Mining only
Tachycardia, Ventricular	Ventricular tachycardia	BEFREE	29275174		★☆☆☆☆ Found in Text Mining only
Ventricular Fibrillation	Ventricular Fibrillation	BEFREE	29275174		★☆☆☆☆ Found in Text Mining only