Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	51710
Gene name	Zinc finger protein 44
Gene symbol	ZNF44
Synonyms (NCBI Gene)	GIOT-2KOX7ZNFZNF504ZNF55ZNF58
Chromosome	19
Chromosome location	19p13.2

111

Show/Hide all (111)

miRTarBase ID	miRNA	Experiments	Reference
MIRT038754	hsa-miR-93-3p	CLASH	23622248
MIRT610846	hsa-miR-4794	HITS-CLIP	23824327
MIRT610845	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT610846	hsa-miR-4794	HITS-CLIP	23824327
MIRT610845	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT610846	hsa-miR-4794	HITS-CLIP	23824327
MIRT610845	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT516812	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT516811	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT516810	hsa-miR-3934-5p	PAR-CLIP	23446348
MIRT516809	hsa-miR-6849-3p	PAR-CLIP	23446348
MIRT516808	hsa-miR-875-3p	PAR-CLIP	23446348
MIRT516807	hsa-miR-4537	PAR-CLIP	23446348
MIRT516806	hsa-miR-5095	PAR-CLIP	23446348
MIRT516805	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT610846	hsa-miR-4794	HITS-CLIP	23824327
MIRT610845	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT610846	hsa-miR-4794	HITS-CLIP	23824327
MIRT610845	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT610846	hsa-miR-4794	HITS-CLIP	23824327
MIRT610845	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT516812	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT516811	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT516810	hsa-miR-3934-5p	PAR-CLIP	23446348
MIRT516809	hsa-miR-6849-3p	PAR-CLIP	23446348
MIRT516808	hsa-miR-875-3p	PAR-CLIP	23446348
MIRT516807	hsa-miR-4537	PAR-CLIP	23446348
MIRT516806	hsa-miR-5095	PAR-CLIP	23446348
MIRT516805	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT1525061	hsa-miR-1254	CLIP-seq
MIRT1525062	hsa-miR-3116	CLIP-seq
MIRT1525063	hsa-miR-3934	CLIP-seq
MIRT1525064	hsa-miR-4633-5p	CLIP-seq
MIRT1525065	hsa-miR-532-5p	CLIP-seq
MIRT1525066	hsa-miR-661	CLIP-seq
MIRT1525067	hsa-miR-1200	CLIP-seq
MIRT1525068	hsa-miR-1297	CLIP-seq
MIRT1525069	hsa-miR-1976	CLIP-seq
MIRT1525070	hsa-miR-26a	CLIP-seq
MIRT1525071	hsa-miR-26b	CLIP-seq
MIRT1525072	hsa-miR-3117-3p	CLIP-seq
MIRT1525073	hsa-miR-3169	CLIP-seq
MIRT1525074	hsa-miR-3200-5p	CLIP-seq
MIRT1525075	hsa-miR-3663-5p	CLIP-seq
MIRT1525076	hsa-miR-3689a-5p	CLIP-seq
MIRT1525077	hsa-miR-3689b	CLIP-seq
MIRT1525078	hsa-miR-3689e	CLIP-seq
MIRT1525079	hsa-miR-3689f	CLIP-seq
MIRT1525080	hsa-miR-4279	CLIP-seq
MIRT1525081	hsa-miR-4320	CLIP-seq
MIRT1525082	hsa-miR-4324	CLIP-seq
MIRT1525083	hsa-miR-4427	CLIP-seq
MIRT1525084	hsa-miR-4465	CLIP-seq
MIRT1525085	hsa-miR-4532	CLIP-seq
MIRT1525086	hsa-miR-4662a-5p	CLIP-seq
MIRT1525087	hsa-miR-4676-5p	CLIP-seq
MIRT1525088	hsa-miR-4680-3p	CLIP-seq
MIRT1525089	hsa-miR-4722-3p	CLIP-seq
MIRT1525090	hsa-miR-4755-3p	CLIP-seq
MIRT1525091	hsa-miR-4759	CLIP-seq
MIRT1525092	hsa-miR-498	CLIP-seq
MIRT1525093	hsa-miR-544b	CLIP-seq
MIRT1525094	hsa-miR-548aa	CLIP-seq
MIRT1525095	hsa-miR-575	CLIP-seq
MIRT1525067	hsa-miR-1200	CLIP-seq
MIRT2378132	hsa-miR-1913	CLIP-seq
MIRT1525069	hsa-miR-1976	CLIP-seq
MIRT1525072	hsa-miR-3117-3p	CLIP-seq
MIRT1525073	hsa-miR-3169	CLIP-seq
MIRT2378133	hsa-miR-3176	CLIP-seq
MIRT2378134	hsa-miR-324-3p	CLIP-seq
MIRT2378135	hsa-miR-3922-3p	CLIP-seq
MIRT1525063	hsa-miR-3934	CLIP-seq
MIRT2378136	hsa-miR-4290	CLIP-seq
MIRT1525082	hsa-miR-4324	CLIP-seq
MIRT2378137	hsa-miR-4667-3p	CLIP-seq
MIRT2378138	hsa-miR-4757-5p	CLIP-seq
MIRT1525091	hsa-miR-4759	CLIP-seq
MIRT1525093	hsa-miR-544b	CLIP-seq
MIRT2378139	hsa-miR-552	CLIP-seq
MIRT2397557	hsa-miR-130a	CLIP-seq
MIRT2397558	hsa-miR-130b	CLIP-seq
MIRT2397559	hsa-miR-199a-3p	CLIP-seq
MIRT2397560	hsa-miR-199b-3p	CLIP-seq
MIRT2397561	hsa-miR-301a	CLIP-seq
MIRT2397562	hsa-miR-301b	CLIP-seq
MIRT2397563	hsa-miR-3129-5p	CLIP-seq
MIRT2397564	hsa-miR-3666	CLIP-seq
MIRT2397565	hsa-miR-4295	CLIP-seq
MIRT2397566	hsa-miR-454	CLIP-seq
MIRT2397567	hsa-miR-4671-3p	CLIP-seq
MIRT2464263	hsa-miR-3688-3p	CLIP-seq
MIRT2464264	hsa-miR-4261	CLIP-seq
MIRT2464265	hsa-miR-4694-3p	CLIP-seq
MIRT2464266	hsa-miR-488	CLIP-seq
MIRT1525069	hsa-miR-1976	CLIP-seq
MIRT1525080	hsa-miR-4279	CLIP-seq
MIRT1525081	hsa-miR-4320	CLIP-seq
MIRT1525085	hsa-miR-4532	CLIP-seq
MIRT1525089	hsa-miR-4722-3p	CLIP-seq
MIRT1525067	hsa-miR-1200	CLIP-seq
MIRT1525069	hsa-miR-1976	CLIP-seq
MIRT1525072	hsa-miR-3117-3p	CLIP-seq
MIRT1525073	hsa-miR-3169	CLIP-seq
MIRT1525080	hsa-miR-4279	CLIP-seq
MIRT1525081	hsa-miR-4320	CLIP-seq
MIRT1525082	hsa-miR-4324	CLIP-seq
MIRT1525085	hsa-miR-4532	CLIP-seq
MIRT1525089	hsa-miR-4722-3p	CLIP-seq
MIRT1525091	hsa-miR-4759	CLIP-seq
MIRT1525093	hsa-miR-544b	CLIP-seq

Show/Hide all (9)

GO ID	Ontology	Definition	Evidence
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
194542	13110	ENSG00000197857

P15621

Protein name

Zinc finger protein 44 (Gonadotropin-inducible ovary transcription repressor 2) (GIOT-2) (Zinc finger protein 55) (Zinc finger protein 58) (Zinc finger protein KOX7)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	51 → 92	KRAB box	Family
PF00096	zf-C2H2	217 → 238	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	245 → 267	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	301 → 323	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	329 → 351	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	357 → 379	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	441 → 463	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	469 → 491	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	524 → 546	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	552 → 574	Zinc finger, C2H2 type	Domain
PF13912	zf-C2H2_6	636 → 661		Domain

Sequence

MALCYGTFWGYPKMLEAANLMEGLVDIGPWVTLPRGQPEVLEWGLPKDQDSVAFEDVAVN
FTHEEWALLGPSQKNLYRDVMRETIRNLNCIGMKWENQNIDDQHQNLRRNPRCDVVERFG
KSKDGSQCGETLSQIRNSIVNKNTPARVDACGSSVNGEVIMGHSSLNCYIRVDTGHKHRE
CHEYAEKSYTHKQCGKGLSYRHSFQTCERPHTGKKPYDCKECGKTFSSPGNLRRHMVVKG
GDGPYKCELCGKAFFWPSLLRMHERTHTGEKPYECKQCSKAFPVYSSYLRHEKIHTGEKP
YECKQCSKAFPDYSSYLRHERTHTGEKPYKCKQCGKAFSVSGSLRVHERIHTGEKPYTCK
QCGKAFCHLGSFQRHMIMHSGDGPHKCKICGKGFDFPGSARIHEGTHTLEKPYECKQCGK
LLSHRSSFRRHMMAHTGDGPHKCTVCGKAFDSPSVFQRHERTHTGEKPYECKQCGKAFRT
SSSLRKHETTHTGEQPYKCKCGKAFSDLFSFQSHETTHSEEEPYECKECGKAFSSFKYFC
RHERTHSEEKSYECQICGKAFSRFSYLKTHERTHTAEKPYECKQCRKAFFWPSFLLRHER
THTGERPYECKHCGKAFSRSSFCREHERTHTGEKPYECKECGKAFSSLSSFNRHKRTHWK
DIL

Sequence length

663

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
OLIGODENDROGLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (13)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Beckwith-Wiedemann Syndrome	Beckwith-Wiedemann Syndrome	BEFREE	7557990		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	25421577		★★★★★ ★☆☆☆☆ Found in Text Mining only
Choroid Plexus Papilloma	Choroid Plexus Papilloma	BEFREE	30466473		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy Generalized	Generalized epilepsy	Pubtator	23686817	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy, Generalized	Epilepsy	BEFREE	23686817		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	BEFREE	19671739, 23372733, 24124608		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	25421577		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	30444046		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	27655485, 28670441, 29370947, 30444046		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	31165610		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30444046, 31165610		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	37161925	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Williams Syndrome	Williams Syndrome	BEFREE	7557990		★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF44 (zinc finger protein 44)