JKAMP (JNK1/MAPK8 associated membrane protein)

Gene

• Entrez ID: 51528
• Gene name: JNK1/MAPK8 associated membrane protein
• Gene symbol: JKAMP
• Synonyms (NCBI Gene): C14orf100, C24orf100, CDA06, HSPC213, HSPC327, JAMP
• Chromosome: 14
• Chromosome location: 14q23.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT571387	hsa-miR-7849-3p	PAR-CLIP	20371350
MIRT571386	hsa-miR-2115-3p	PAR-CLIP	20371350
MIRT571385	hsa-miR-4307	PAR-CLIP	20371350
MIRT571384	hsa-miR-125b-2-3p	PAR-CLIP	20371350
MIRT571383	hsa-miR-567	PAR-CLIP	20371350
MIRT571382	hsa-miR-8068	PAR-CLIP	20371350
MIRT571381	hsa-miR-361-5p	PAR-CLIP	20371350
MIRT571380	hsa-miR-2681-5p	PAR-CLIP	20371350
MIRT571387	hsa-miR-7849-3p	PAR-CLIP	20371350
MIRT571386	hsa-miR-2115-3p	PAR-CLIP	20371350
MIRT571385	hsa-miR-4307	PAR-CLIP	20371350
MIRT571384	hsa-miR-125b-2-3p	PAR-CLIP	20371350
MIRT571383	hsa-miR-567	PAR-CLIP	20371350
MIRT571382	hsa-miR-8068	PAR-CLIP	20371350
MIRT571381	hsa-miR-361-5p	PAR-CLIP	20371350
MIRT571380	hsa-miR-2681-5p	PAR-CLIP	20371350
MIRT571387	hsa-miR-7849-3p	PAR-CLIP	20371350
MIRT571386	hsa-miR-2115-3p	PAR-CLIP	20371350
MIRT571385	hsa-miR-4307	PAR-CLIP	20371350
MIRT571384	hsa-miR-125b-2-3p	PAR-CLIP	20371350
MIRT571383	hsa-miR-567	PAR-CLIP	20371350
MIRT571382	hsa-miR-8068	PAR-CLIP	20371350
MIRT571381	hsa-miR-361-5p	PAR-CLIP	20371350
MIRT571380	hsa-miR-2681-5p	PAR-CLIP	20371350
MIRT571387	hsa-miR-7849-3p	PAR-CLIP	20371350
MIRT571386	hsa-miR-2115-3p	PAR-CLIP	20371350
MIRT571385	hsa-miR-4307	PAR-CLIP	20371350
MIRT571384	hsa-miR-125b-2-3p	PAR-CLIP	20371350
MIRT571383	hsa-miR-567	PAR-CLIP	20371350
MIRT571382	hsa-miR-8068	PAR-CLIP	20371350
MIRT571381	hsa-miR-361-5p	PAR-CLIP	20371350
MIRT571380	hsa-miR-2681-5p	PAR-CLIP	20371350
MIRT1076818	hsa-miR-377	CLIP-seq
MIRT1076819	hsa-miR-4528	CLIP-seq
MIRT1076820	hsa-miR-4760-3p	CLIP-seq
MIRT1076821	hsa-miR-664	CLIP-seq
MIRT1076822	hsa-miR-1257	CLIP-seq
MIRT1076823	hsa-miR-145	CLIP-seq
MIRT1076824	hsa-miR-1825	CLIP-seq
MIRT1076825	hsa-miR-199a-5p	CLIP-seq
MIRT1076826	hsa-miR-199b-5p	CLIP-seq
MIRT1076827	hsa-miR-3158-3p	CLIP-seq
MIRT1076828	hsa-miR-3174	CLIP-seq
MIRT1076829	hsa-miR-3609	CLIP-seq
MIRT1076830	hsa-miR-384	CLIP-seq
MIRT1076831	hsa-miR-4280	CLIP-seq
MIRT1076832	hsa-miR-4297	CLIP-seq
MIRT1076833	hsa-miR-4452	CLIP-seq
MIRT1076834	hsa-miR-4700-3p	CLIP-seq
MIRT1076835	hsa-miR-516a-3p	CLIP-seq
MIRT1076836	hsa-miR-548ah	CLIP-seq
MIRT1076837	hsa-miR-548t	CLIP-seq
MIRT2019119	hsa-miR-1266	CLIP-seq
MIRT2019120	hsa-miR-1301	CLIP-seq
MIRT1076823	hsa-miR-145	CLIP-seq
MIRT1076824	hsa-miR-1825	CLIP-seq
MIRT1076825	hsa-miR-199a-5p	CLIP-seq
MIRT1076826	hsa-miR-199b-5p	CLIP-seq
MIRT2019121	hsa-miR-28-5p	CLIP-seq
MIRT2019122	hsa-miR-3139	CLIP-seq
MIRT2019123	hsa-miR-3664-3p	CLIP-seq
MIRT1076830	hsa-miR-384	CLIP-seq
MIRT2019124	hsa-miR-4266	CLIP-seq
MIRT1076831	hsa-miR-4280	CLIP-seq
MIRT1076832	hsa-miR-4297	CLIP-seq
MIRT2019125	hsa-miR-450b-5p	CLIP-seq
MIRT2019126	hsa-miR-4518	CLIP-seq
MIRT2019127	hsa-miR-4660	CLIP-seq
MIRT2019128	hsa-miR-4684-3p	CLIP-seq
MIRT2019129	hsa-miR-4753-5p	CLIP-seq
MIRT2019130	hsa-miR-5047	CLIP-seq
MIRT2019131	hsa-miR-507	CLIP-seq
MIRT1076835	hsa-miR-516a-3p	CLIP-seq
MIRT2019132	hsa-miR-557	CLIP-seq
MIRT2019133	hsa-miR-627	CLIP-seq
MIRT2019134	hsa-miR-708	CLIP-seq
MIRT2019135	hsa-miR-924	CLIP-seq
MIRT2251021	hsa-miR-1208	CLIP-seq
MIRT2251022	hsa-miR-1227	CLIP-seq
MIRT2251023	hsa-miR-1264	CLIP-seq
MIRT2251024	hsa-miR-1288	CLIP-seq
MIRT1076823	hsa-miR-145	CLIP-seq
MIRT1076824	hsa-miR-1825	CLIP-seq
MIRT1076825	hsa-miR-199a-5p	CLIP-seq
MIRT1076826	hsa-miR-199b-5p	CLIP-seq
MIRT2019121	hsa-miR-28-5p	CLIP-seq
MIRT2019122	hsa-miR-3139	CLIP-seq
MIRT1076827	hsa-miR-3158-3p	CLIP-seq
MIRT2251025	hsa-miR-3158-5p	CLIP-seq
MIRT2251026	hsa-miR-3169	CLIP-seq
MIRT2251027	hsa-miR-320a	CLIP-seq
MIRT2251028	hsa-miR-320b	CLIP-seq
MIRT2251029	hsa-miR-320c	CLIP-seq
MIRT2251030	hsa-miR-320d	CLIP-seq
MIRT2251031	hsa-miR-3607-3p	CLIP-seq
MIRT2251032	hsa-miR-3686	CLIP-seq
MIRT2251033	hsa-miR-3691-3p	CLIP-seq
MIRT1076830	hsa-miR-384	CLIP-seq
MIRT2251034	hsa-miR-4252	CLIP-seq
MIRT2019124	hsa-miR-4266	CLIP-seq
MIRT2251035	hsa-miR-4275	CLIP-seq
MIRT1076831	hsa-miR-4280	CLIP-seq
MIRT1076832	hsa-miR-4297	CLIP-seq
MIRT2251036	hsa-miR-4418	CLIP-seq
MIRT2251037	hsa-miR-4429	CLIP-seq
MIRT2251038	hsa-miR-4477b	CLIP-seq
MIRT2251039	hsa-miR-4699-3p	CLIP-seq
MIRT2251040	hsa-miR-509-3-5p	CLIP-seq
MIRT2251041	hsa-miR-509-5p	CLIP-seq
MIRT1076835	hsa-miR-516a-3p	CLIP-seq
MIRT2251042	hsa-miR-556-3p	CLIP-seq
MIRT2251043	hsa-miR-595	CLIP-seq
MIRT2019134	hsa-miR-708	CLIP-seq
MIRT2251021	hsa-miR-1208	CLIP-seq
MIRT2389549	hsa-miR-485-3p	CLIP-seq
MIRT2251021	hsa-miR-1208	CLIP-seq
MIRT2430210	hsa-miR-3168	CLIP-seq
MIRT2389549	hsa-miR-485-3p	CLIP-seq
MIRT2554417	hsa-miR-10a	CLIP-seq
MIRT2554418	hsa-miR-10b	CLIP-seq
MIRT2251021	hsa-miR-1208	CLIP-seq
MIRT2554419	hsa-miR-1256	CLIP-seq
MIRT2251023	hsa-miR-1264	CLIP-seq
MIRT2019119	hsa-miR-1266	CLIP-seq
MIRT2554420	hsa-miR-1267	CLIP-seq
MIRT2554421	hsa-miR-1271	CLIP-seq
MIRT2554422	hsa-miR-1279	CLIP-seq
MIRT2251024	hsa-miR-1288	CLIP-seq
MIRT2554423	hsa-miR-1292	CLIP-seq
MIRT2019120	hsa-miR-1301	CLIP-seq
MIRT1076823	hsa-miR-145	CLIP-seq
MIRT2554424	hsa-miR-182	CLIP-seq
MIRT1076824	hsa-miR-1825	CLIP-seq
MIRT2554425	hsa-miR-186	CLIP-seq
MIRT2554426	hsa-miR-194	CLIP-seq
MIRT1076825	hsa-miR-199a-5p	CLIP-seq
MIRT1076826	hsa-miR-199b-5p	CLIP-seq
MIRT2554427	hsa-miR-2053	CLIP-seq
MIRT2554428	hsa-miR-23a	CLIP-seq
MIRT2554429	hsa-miR-23b	CLIP-seq
MIRT2554430	hsa-miR-23c	CLIP-seq
MIRT2019121	hsa-miR-28-5p	CLIP-seq
MIRT2554431	hsa-miR-3125	CLIP-seq
MIRT2554432	hsa-miR-3133	CLIP-seq
MIRT2019122	hsa-miR-3139	CLIP-seq
MIRT2554433	hsa-miR-3157-3p	CLIP-seq
MIRT1076827	hsa-miR-3158-3p	CLIP-seq
MIRT2251025	hsa-miR-3158-5p	CLIP-seq
MIRT2554434	hsa-miR-3163	CLIP-seq
MIRT2430210	hsa-miR-3168	CLIP-seq
MIRT2251026	hsa-miR-3169	CLIP-seq
MIRT2251027	hsa-miR-320a	CLIP-seq
MIRT2251028	hsa-miR-320b	CLIP-seq
MIRT2251029	hsa-miR-320c	CLIP-seq
MIRT2251030	hsa-miR-320d	CLIP-seq
MIRT2554435	hsa-miR-326	CLIP-seq
MIRT2554436	hsa-miR-330-5p	CLIP-seq
MIRT2554437	hsa-miR-33a	CLIP-seq
MIRT2554438	hsa-miR-33b	CLIP-seq
MIRT2554439	hsa-miR-3545-3p	CLIP-seq
MIRT2251031	hsa-miR-3607-3p	CLIP-seq
MIRT1076829	hsa-miR-3609	CLIP-seq
MIRT2554440	hsa-miR-3618	CLIP-seq
MIRT2554441	hsa-miR-3662	CLIP-seq
MIRT2019123	hsa-miR-3664-3p	CLIP-seq
MIRT2554442	hsa-miR-3675-3p	CLIP-seq
MIRT2251032	hsa-miR-3686	CLIP-seq
MIRT2251033	hsa-miR-3691-3p	CLIP-seq
MIRT1076830	hsa-miR-384	CLIP-seq
MIRT2554443	hsa-miR-3916	CLIP-seq
MIRT2554444	hsa-miR-3924	CLIP-seq
MIRT2251034	hsa-miR-4252	CLIP-seq
MIRT2019124	hsa-miR-4266	CLIP-seq
MIRT2251035	hsa-miR-4275	CLIP-seq
MIRT1076831	hsa-miR-4280	CLIP-seq
MIRT1076832	hsa-miR-4297	CLIP-seq
MIRT2554445	hsa-miR-4325	CLIP-seq
MIRT2251036	hsa-miR-4418	CLIP-seq
MIRT2251037	hsa-miR-4429	CLIP-seq
MIRT2554446	hsa-miR-4471	CLIP-seq
MIRT2251038	hsa-miR-4477b	CLIP-seq
MIRT2554447	hsa-miR-4496	CLIP-seq
MIRT2019125	hsa-miR-450b-5p	CLIP-seq
MIRT2019126	hsa-miR-4518	CLIP-seq
MIRT2554448	hsa-miR-4539	CLIP-seq
MIRT2554449	hsa-miR-4642	CLIP-seq
MIRT2019127	hsa-miR-4660	CLIP-seq
MIRT2554450	hsa-miR-4672	CLIP-seq
MIRT2251039	hsa-miR-4699-3p	CLIP-seq
MIRT2554451	hsa-miR-4712-3p	CLIP-seq
MIRT2554452	hsa-miR-4717-3p	CLIP-seq
MIRT2554453	hsa-miR-4719	CLIP-seq
MIRT2554454	hsa-miR-4740-3p	CLIP-seq
MIRT2554455	hsa-miR-4744	CLIP-seq
MIRT2554456	hsa-miR-4773	CLIP-seq
MIRT2554457	hsa-miR-4782-5p	CLIP-seq
MIRT2554458	hsa-miR-4797-5p	CLIP-seq
MIRT2389549	hsa-miR-485-3p	CLIP-seq
MIRT2554459	hsa-miR-494	CLIP-seq
MIRT2554460	hsa-miR-496	CLIP-seq
MIRT2019130	hsa-miR-5047	CLIP-seq
MIRT2019131	hsa-miR-507	CLIP-seq
MIRT2251040	hsa-miR-509-3-5p	CLIP-seq
MIRT2251041	hsa-miR-509-5p	CLIP-seq
MIRT1076835	hsa-miR-516a-3p	CLIP-seq
MIRT2554461	hsa-miR-520g	CLIP-seq
MIRT2554462	hsa-miR-520h	CLIP-seq
MIRT1076836	hsa-miR-548ah	CLIP-seq
MIRT2251042	hsa-miR-556-3p	CLIP-seq
MIRT2019132	hsa-miR-557	CLIP-seq
MIRT2554463	hsa-miR-569	CLIP-seq
MIRT2554464	hsa-miR-633	CLIP-seq
MIRT2019134	hsa-miR-708	CLIP-seq
MIRT2554465	hsa-miR-874	CLIP-seq
MIRT2554466	hsa-miR-934	CLIP-seq
MIRT2554467	hsa-miR-96	CLIP-seq
MIRT2554417	hsa-miR-10a	CLIP-seq
MIRT2554418	hsa-miR-10b	CLIP-seq
MIRT2251021	hsa-miR-1208	CLIP-seq
MIRT2554419	hsa-miR-1256	CLIP-seq
MIRT2019119	hsa-miR-1266	CLIP-seq
MIRT2554420	hsa-miR-1267	CLIP-seq
MIRT2554421	hsa-miR-1271	CLIP-seq
MIRT2554422	hsa-miR-1279	CLIP-seq
MIRT2251024	hsa-miR-1288	CLIP-seq
MIRT2554423	hsa-miR-1292	CLIP-seq
MIRT2019120	hsa-miR-1301	CLIP-seq
MIRT1076823	hsa-miR-145	CLIP-seq
MIRT2554424	hsa-miR-182	CLIP-seq
MIRT1076824	hsa-miR-1825	CLIP-seq
MIRT2554425	hsa-miR-186	CLIP-seq
MIRT2554426	hsa-miR-194	CLIP-seq
MIRT1076825	hsa-miR-199a-5p	CLIP-seq
MIRT1076826	hsa-miR-199b-5p	CLIP-seq
MIRT2554427	hsa-miR-2053	CLIP-seq
MIRT2019121	hsa-miR-28-5p	CLIP-seq
MIRT2554432	hsa-miR-3133	CLIP-seq
MIRT2019122	hsa-miR-3139	CLIP-seq
MIRT2554433	hsa-miR-3157-3p	CLIP-seq
MIRT1076827	hsa-miR-3158-3p	CLIP-seq
MIRT2251025	hsa-miR-3158-5p	CLIP-seq
MIRT2554434	hsa-miR-3163	CLIP-seq
MIRT2430210	hsa-miR-3168	CLIP-seq
MIRT2251026	hsa-miR-3169	CLIP-seq
MIRT2683107	hsa-miR-3182	CLIP-seq
MIRT2251027	hsa-miR-320a	CLIP-seq
MIRT2251028	hsa-miR-320b	CLIP-seq
MIRT2251029	hsa-miR-320c	CLIP-seq
MIRT2251030	hsa-miR-320d	CLIP-seq
MIRT2554435	hsa-miR-326	CLIP-seq
MIRT2554436	hsa-miR-330-5p	CLIP-seq
MIRT2554437	hsa-miR-33a	CLIP-seq
MIRT2554438	hsa-miR-33b	CLIP-seq
MIRT2554439	hsa-miR-3545-3p	CLIP-seq
MIRT2251031	hsa-miR-3607-3p	CLIP-seq
MIRT1076829	hsa-miR-3609	CLIP-seq
MIRT2554441	hsa-miR-3662	CLIP-seq
MIRT2019123	hsa-miR-3664-3p	CLIP-seq
MIRT2554442	hsa-miR-3675-3p	CLIP-seq
MIRT2251032	hsa-miR-3686	CLIP-seq
MIRT2251033	hsa-miR-3691-3p	CLIP-seq
MIRT1076830	hsa-miR-384	CLIP-seq
MIRT2251034	hsa-miR-4252	CLIP-seq
MIRT2019124	hsa-miR-4266	CLIP-seq
MIRT2251035	hsa-miR-4275	CLIP-seq
MIRT1076831	hsa-miR-4280	CLIP-seq
MIRT1076832	hsa-miR-4297	CLIP-seq
MIRT2554445	hsa-miR-4325	CLIP-seq
MIRT2251036	hsa-miR-4418	CLIP-seq
MIRT2251037	hsa-miR-4429	CLIP-seq
MIRT2554446	hsa-miR-4471	CLIP-seq
MIRT2251038	hsa-miR-4477b	CLIP-seq
MIRT2019125	hsa-miR-450b-5p	CLIP-seq
MIRT2019126	hsa-miR-4518	CLIP-seq
MIRT2554448	hsa-miR-4539	CLIP-seq
MIRT2554449	hsa-miR-4642	CLIP-seq
MIRT2019127	hsa-miR-4660	CLIP-seq
MIRT2554450	hsa-miR-4672	CLIP-seq
MIRT2251039	hsa-miR-4699-3p	CLIP-seq
MIRT2554453	hsa-miR-4719	CLIP-seq
MIRT2683108	hsa-miR-4742-3p	CLIP-seq
MIRT2554455	hsa-miR-4744	CLIP-seq
MIRT2554456	hsa-miR-4773	CLIP-seq
MIRT2554457	hsa-miR-4782-5p	CLIP-seq
MIRT2554458	hsa-miR-4797-5p	CLIP-seq
MIRT2389549	hsa-miR-485-3p	CLIP-seq
MIRT2554459	hsa-miR-494	CLIP-seq
MIRT2554460	hsa-miR-496	CLIP-seq
MIRT2019130	hsa-miR-5047	CLIP-seq
MIRT2019131	hsa-miR-507	CLIP-seq
MIRT2251040	hsa-miR-509-3-5p	CLIP-seq
MIRT2251041	hsa-miR-509-5p	CLIP-seq
MIRT1076835	hsa-miR-516a-3p	CLIP-seq
MIRT2554461	hsa-miR-520g	CLIP-seq
MIRT2554462	hsa-miR-520h	CLIP-seq
MIRT1076836	hsa-miR-548ah	CLIP-seq
MIRT2251042	hsa-miR-556-3p	CLIP-seq
MIRT2019132	hsa-miR-557	CLIP-seq
MIRT2554463	hsa-miR-569	CLIP-seq
MIRT2554464	hsa-miR-633	CLIP-seq
MIRT2019134	hsa-miR-708	CLIP-seq
MIRT2554465	hsa-miR-874	CLIP-seq
MIRT2554467	hsa-miR-96	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0006986	Process	Response to unfolded protein	IEA
GO:0016020	Component	Membrane	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IBA
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	19269966
GO:0036503	Process	ERAD pathway	IBA
GO:0036503	Process	ERAD pathway	IDA	19269966

Other IDs

• MIM: 611176
• HGNC: 20184
• e!Ensembl: ENSG00000050130

Protein

• UniProt ID: Q9P055
• Protein name: JNK1/MAPK8-associated membrane protein (JKAMP) (JNK1-associated membrane protein) (JAMP) (Medulloblastoma antigen MU-MB-50.4)
• Protein function: Regulates the duration of MAPK8 activity in response to various stress stimuli (By similarity). Facilitates degradation of misfolded endoplasmic reticulum (ER) proteins through the recruitment of components of the proteasome and endoplasmic reti
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05571	JAMP	17 → 308	JNK1/MAPK8-associated membrane protein	Family

• Sequence:

  MAVDIQPACLGLYCGKTLLFKNGSTEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLY
  LGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSC
  RVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPLLVKKIA
  CGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIEN
  CYDLLVRKKRLIVLFSHWLLHAYGIISISRVDKLEQDLPLLALVPTPALFYLFTAKFTEP
  SRILSEGANGH

• Sequence length: 311

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations