Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	51317
Gene name	PHD finger protein 21A
Gene symbol	PHF21A
Synonyms (NCBI Gene)	BHC80BM-006IDDBCSNEDMS
Chromosome	11
Chromosome location	11p11.2
Summary	The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1554988946	G>A	Likely-pathogenic	Coding sequence variant, non coding transcript variant, stop gained
rs1591092743	C>T	Pathogenic	Coding sequence variant, missense variant, non coding transcript variant
rs1591102099	->G	Pathogenic	Coding sequence variant, frameshift variant, non coding transcript variant
rs1591407093	AG>-	Pathogenic	Coding sequence variant, frameshift variant, non coding transcript variant
rs1591407315	->TT	Pathogenic	Coding sequence variant, frameshift variant, non coding transcript variant

412

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016996	hsa-miR-335-5p	Microarray	18185580
MIRT046927	hsa-miR-221-3p	CLASH	23622248
MIRT655160	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT655159	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT655158	hsa-miR-7855-5p	HITS-CLIP	23824327
MIRT655157	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT655160	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT655159	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT655158	hsa-miR-7855-5p	HITS-CLIP	23824327
MIRT655157	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT1230790	hsa-miR-1208	CLIP-seq
MIRT1230791	hsa-miR-1254	CLIP-seq
MIRT1230792	hsa-miR-1283	CLIP-seq
MIRT1230793	hsa-miR-1324	CLIP-seq
MIRT1230794	hsa-miR-216a	CLIP-seq
MIRT1230795	hsa-miR-3116	CLIP-seq
MIRT1230796	hsa-miR-3166	CLIP-seq
MIRT1230797	hsa-miR-3616-5p	CLIP-seq
MIRT1230798	hsa-miR-3647-5p	CLIP-seq
MIRT1230799	hsa-miR-3690	CLIP-seq
MIRT1230800	hsa-miR-370	CLIP-seq
MIRT1230801	hsa-miR-3921	CLIP-seq
MIRT1230802	hsa-miR-4254	CLIP-seq
MIRT1230803	hsa-miR-4299	CLIP-seq
MIRT1230804	hsa-miR-4305	CLIP-seq
MIRT1230805	hsa-miR-4428	CLIP-seq
MIRT1230806	hsa-miR-4436b-3p	CLIP-seq
MIRT1230807	hsa-miR-4456	CLIP-seq
MIRT1230808	hsa-miR-4653-5p	CLIP-seq
MIRT1230809	hsa-miR-4717-5p	CLIP-seq
MIRT1230810	hsa-miR-4795-5p	CLIP-seq
MIRT1230811	hsa-miR-513a-3p	CLIP-seq
MIRT1230812	hsa-miR-513c	CLIP-seq
MIRT1230813	hsa-miR-514b-5p	CLIP-seq
MIRT1230814	hsa-miR-520d-5p	CLIP-seq
MIRT1230815	hsa-miR-524-5p	CLIP-seq
MIRT1230816	hsa-miR-548q	CLIP-seq
MIRT1230817	hsa-miR-550a	CLIP-seq
MIRT1230818	hsa-miR-573	CLIP-seq
MIRT1230819	hsa-miR-596	CLIP-seq
MIRT1230820	hsa-miR-661	CLIP-seq
MIRT1230790	hsa-miR-1208	CLIP-seq
MIRT1230821	hsa-miR-1262	CLIP-seq
MIRT1230792	hsa-miR-1283	CLIP-seq
MIRT1230822	hsa-miR-1293	CLIP-seq
MIRT1230823	hsa-miR-1297	CLIP-seq
MIRT1230824	hsa-miR-1305	CLIP-seq
MIRT1230825	hsa-miR-1321	CLIP-seq
MIRT1230826	hsa-miR-1343	CLIP-seq
MIRT1230827	hsa-miR-140-3p	CLIP-seq
MIRT1230828	hsa-miR-185	CLIP-seq
MIRT1230829	hsa-miR-2054	CLIP-seq
MIRT1230830	hsa-miR-2355-5p	CLIP-seq
MIRT1230831	hsa-miR-26a	CLIP-seq
MIRT1230832	hsa-miR-26b	CLIP-seq
MIRT1230833	hsa-miR-3117-5p	CLIP-seq
MIRT1230834	hsa-miR-3202	CLIP-seq
MIRT1230835	hsa-miR-34b	CLIP-seq
MIRT1230797	hsa-miR-3616-5p	CLIP-seq
MIRT1230798	hsa-miR-3647-5p	CLIP-seq
MIRT1230836	hsa-miR-3649	CLIP-seq
MIRT1230837	hsa-miR-3667-3p	CLIP-seq
MIRT1230838	hsa-miR-3679-3p	CLIP-seq
MIRT1230839	hsa-miR-3689a-3p	CLIP-seq
MIRT1230840	hsa-miR-3689c	CLIP-seq
MIRT1230799	hsa-miR-3690	CLIP-seq
MIRT1230801	hsa-miR-3921	CLIP-seq
MIRT1230841	hsa-miR-3925-3p	CLIP-seq
MIRT1230802	hsa-miR-4254	CLIP-seq
MIRT1230842	hsa-miR-4261	CLIP-seq
MIRT1230843	hsa-miR-4265	CLIP-seq
MIRT1230844	hsa-miR-4296	CLIP-seq
MIRT1230845	hsa-miR-4306	CLIP-seq
MIRT1230846	hsa-miR-4312	CLIP-seq
MIRT1230847	hsa-miR-4322	CLIP-seq
MIRT1230848	hsa-miR-4420	CLIP-seq
MIRT1230849	hsa-miR-4446-5p	CLIP-seq
MIRT1230850	hsa-miR-4465	CLIP-seq
MIRT1230851	hsa-miR-4476	CLIP-seq
MIRT1230852	hsa-miR-4483	CLIP-seq
MIRT1230853	hsa-miR-4496	CLIP-seq
MIRT1230854	hsa-miR-4512	CLIP-seq
MIRT1230855	hsa-miR-452	CLIP-seq
MIRT1230856	hsa-miR-4638-3p	CLIP-seq
MIRT1230857	hsa-miR-4644	CLIP-seq
MIRT1230858	hsa-miR-4648	CLIP-seq
MIRT1230808	hsa-miR-4653-5p	CLIP-seq
MIRT1230859	hsa-miR-4654	CLIP-seq
MIRT1230860	hsa-miR-4661-3p	CLIP-seq
MIRT1230861	hsa-miR-4668-3p	CLIP-seq
MIRT1230862	hsa-miR-4676-3p	CLIP-seq
MIRT1230863	hsa-miR-4701-3p	CLIP-seq
MIRT1230864	hsa-miR-4719	CLIP-seq
MIRT1230865	hsa-miR-4724-3p	CLIP-seq
MIRT1230866	hsa-miR-4728-5p	CLIP-seq
MIRT1230867	hsa-miR-4738-5p	CLIP-seq
MIRT1230868	hsa-miR-4739	CLIP-seq
MIRT1230869	hsa-miR-4756-5p	CLIP-seq
MIRT1230870	hsa-miR-4762-5p	CLIP-seq
MIRT1230871	hsa-miR-4769-5p	CLIP-seq
MIRT1230872	hsa-miR-4775	CLIP-seq
MIRT1230810	hsa-miR-4795-5p	CLIP-seq
MIRT1230873	hsa-miR-498	CLIP-seq
MIRT1230814	hsa-miR-520d-5p	CLIP-seq
MIRT1230815	hsa-miR-524-5p	CLIP-seq
MIRT1230874	hsa-miR-561	CLIP-seq
MIRT1230818	hsa-miR-573	CLIP-seq
MIRT1230875	hsa-miR-590-3p	CLIP-seq
MIRT1230876	hsa-miR-640	CLIP-seq
MIRT1230877	hsa-miR-651	CLIP-seq
MIRT1230878	hsa-miR-766	CLIP-seq
MIRT1230879	hsa-miR-933	CLIP-seq
MIRT1230805	hsa-miR-4428	CLIP-seq
MIRT2067751	hsa-miR-1323	CLIP-seq
MIRT2067752	hsa-miR-3660	CLIP-seq
MIRT2067753	hsa-miR-377	CLIP-seq
MIRT2067754	hsa-miR-383	CLIP-seq
MIRT1230841	hsa-miR-3925-3p	CLIP-seq
MIRT1230842	hsa-miR-4261	CLIP-seq
MIRT2067755	hsa-miR-4526	CLIP-seq
MIRT1230864	hsa-miR-4719	CLIP-seq
MIRT2067756	hsa-miR-4772-5p	CLIP-seq
MIRT2067757	hsa-miR-548o	CLIP-seq
MIRT1230878	hsa-miR-766	CLIP-seq
MIRT2067758	hsa-miR-942	CLIP-seq
MIRT2067759	hsa-miR-1205	CLIP-seq
MIRT1230790	hsa-miR-1208	CLIP-seq
MIRT2067760	hsa-miR-1269	CLIP-seq
MIRT2067761	hsa-miR-1269b	CLIP-seq
MIRT2067762	hsa-miR-1288	CLIP-seq
MIRT2067763	hsa-miR-28-5p	CLIP-seq
MIRT2067764	hsa-miR-31	CLIP-seq
MIRT1230833	hsa-miR-3117-5p	CLIP-seq
MIRT2067765	hsa-miR-3123	CLIP-seq
MIRT2067766	hsa-miR-3139	CLIP-seq
MIRT2067767	hsa-miR-3184	CLIP-seq
MIRT1230835	hsa-miR-34b	CLIP-seq
MIRT2067768	hsa-miR-3612	CLIP-seq
MIRT2067769	hsa-miR-3685	CLIP-seq
MIRT1230801	hsa-miR-3921	CLIP-seq
MIRT2067770	hsa-miR-423-5p	CLIP-seq
MIRT1230842	hsa-miR-4261	CLIP-seq
MIRT2067771	hsa-miR-4269	CLIP-seq
MIRT2067772	hsa-miR-4443	CLIP-seq
MIRT1230853	hsa-miR-4496	CLIP-seq
MIRT2067773	hsa-miR-4515	CLIP-seq
MIRT1230855	hsa-miR-452	CLIP-seq
MIRT2067774	hsa-miR-4527	CLIP-seq
MIRT2067775	hsa-miR-4529-3p	CLIP-seq
MIRT1230808	hsa-miR-4653-5p	CLIP-seq
MIRT1230862	hsa-miR-4676-3p	CLIP-seq
MIRT2067776	hsa-miR-4682	CLIP-seq
MIRT2067777	hsa-miR-4687-3p	CLIP-seq
MIRT2067778	hsa-miR-4708-3p	CLIP-seq
MIRT2067779	hsa-miR-4712-3p	CLIP-seq
MIRT2067780	hsa-miR-4740-5p	CLIP-seq
MIRT2067781	hsa-miR-4790-3p	CLIP-seq
MIRT2067782	hsa-miR-485-5p	CLIP-seq
MIRT2067783	hsa-miR-513b	CLIP-seq
MIRT2067784	hsa-miR-603	CLIP-seq
MIRT2067785	hsa-miR-627	CLIP-seq
MIRT2067786	hsa-miR-633	CLIP-seq
MIRT2067787	hsa-miR-650	CLIP-seq
MIRT1230877	hsa-miR-651	CLIP-seq
MIRT2067788	hsa-miR-708	CLIP-seq
MIRT2067789	hsa-miR-924	CLIP-seq
MIRT2067758	hsa-miR-942	CLIP-seq
MIRT2295190	hsa-miR-122	CLIP-seq
MIRT2295191	hsa-miR-1252	CLIP-seq
MIRT1230791	hsa-miR-1254	CLIP-seq
MIRT2295192	hsa-miR-125a-3p	CLIP-seq
MIRT1230821	hsa-miR-1262	CLIP-seq
MIRT2067760	hsa-miR-1269	CLIP-seq
MIRT2067761	hsa-miR-1269b	CLIP-seq
MIRT2295193	hsa-miR-1270	CLIP-seq
MIRT1230826	hsa-miR-1343	CLIP-seq
MIRT2295194	hsa-miR-143	CLIP-seq
MIRT1230828	hsa-miR-185	CLIP-seq
MIRT2295195	hsa-miR-1915	CLIP-seq
MIRT2295196	hsa-miR-214	CLIP-seq
MIRT2295197	hsa-miR-2277-3p	CLIP-seq
MIRT2067763	hsa-miR-28-5p	CLIP-seq
MIRT2295198	hsa-miR-2861	CLIP-seq
MIRT2295199	hsa-miR-3064-5p	CLIP-seq
MIRT1230795	hsa-miR-3116	CLIP-seq
MIRT1230833	hsa-miR-3117-5p	CLIP-seq
MIRT2295200	hsa-miR-3120-3p	CLIP-seq
MIRT2067765	hsa-miR-3123	CLIP-seq
MIRT2295201	hsa-miR-3128	CLIP-seq
MIRT2295202	hsa-miR-3133	CLIP-seq
MIRT2067766	hsa-miR-3139	CLIP-seq
MIRT2295203	hsa-miR-3160-3p	CLIP-seq
MIRT2295204	hsa-miR-3182	CLIP-seq
MIRT2295205	hsa-miR-323-5p	CLIP-seq
MIRT2295206	hsa-miR-331-3p	CLIP-seq
MIRT2295207	hsa-miR-345	CLIP-seq
MIRT2295208	hsa-miR-3614-5p	CLIP-seq
MIRT2295209	hsa-miR-3619-5p	CLIP-seq
MIRT2295210	hsa-miR-3622b-5p	CLIP-seq
MIRT1230837	hsa-miR-3667-3p	CLIP-seq
MIRT2067769	hsa-miR-3685	CLIP-seq
MIRT1230799	hsa-miR-3690	CLIP-seq
MIRT2295211	hsa-miR-3907	CLIP-seq
MIRT2295212	hsa-miR-3918	CLIP-seq
MIRT1230802	hsa-miR-4254	CLIP-seq
MIRT2295213	hsa-miR-4257	CLIP-seq
MIRT2295214	hsa-miR-4292	CLIP-seq
MIRT2295215	hsa-miR-4303	CLIP-seq
MIRT1230845	hsa-miR-4306	CLIP-seq
MIRT2295216	hsa-miR-431	CLIP-seq
MIRT1230846	hsa-miR-4312	CLIP-seq
MIRT2295217	hsa-miR-432	CLIP-seq
MIRT2295218	hsa-miR-4417	CLIP-seq
MIRT2295219	hsa-miR-4421	CLIP-seq
MIRT1230805	hsa-miR-4428	CLIP-seq
MIRT2295220	hsa-miR-4470	CLIP-seq
MIRT2295221	hsa-miR-4481	CLIP-seq
MIRT1230854	hsa-miR-4512	CLIP-seq
MIRT2295222	hsa-miR-4520b-3p	CLIP-seq
MIRT2067775	hsa-miR-4529-3p	CLIP-seq
MIRT2295223	hsa-miR-4531	CLIP-seq
MIRT2295224	hsa-miR-4533	CLIP-seq
MIRT1230856	hsa-miR-4638-3p	CLIP-seq
MIRT2295225	hsa-miR-4642	CLIP-seq
MIRT1230857	hsa-miR-4644	CLIP-seq
MIRT2295226	hsa-miR-4646-5p	CLIP-seq
MIRT2295227	hsa-miR-4649-3p	CLIP-seq
MIRT2295228	hsa-miR-4684-5p	CLIP-seq
MIRT2295229	hsa-miR-4685-5p	CLIP-seq
MIRT1230863	hsa-miR-4701-3p	CLIP-seq
MIRT2067778	hsa-miR-4708-3p	CLIP-seq
MIRT1230864	hsa-miR-4719	CLIP-seq
MIRT2295230	hsa-miR-4726-3p	CLIP-seq
MIRT2295231	hsa-miR-4745-5p	CLIP-seq
MIRT2295232	hsa-miR-4747-5p	CLIP-seq
MIRT2295233	hsa-miR-4770	CLIP-seq
MIRT2295234	hsa-miR-4778-3p	CLIP-seq
MIRT2295235	hsa-miR-4795-3p	CLIP-seq
MIRT2295236	hsa-miR-511	CLIP-seq
MIRT2295237	hsa-miR-513a-5p	CLIP-seq
MIRT2067783	hsa-miR-513b	CLIP-seq
MIRT1230812	hsa-miR-513c	CLIP-seq
MIRT1230813	hsa-miR-514b-5p	CLIP-seq
MIRT2295238	hsa-miR-548b-3p	CLIP-seq
MIRT2295239	hsa-miR-620	CLIP-seq
MIRT2295240	hsa-miR-642b	CLIP-seq
MIRT2067788	hsa-miR-708	CLIP-seq
MIRT2295241	hsa-miR-761	CLIP-seq
MIRT2295242	hsa-miR-9	CLIP-seq
MIRT2067789	hsa-miR-924	CLIP-seq
MIRT2067758	hsa-miR-942	CLIP-seq
MIRT2067760	hsa-miR-1269	CLIP-seq
MIRT2067761	hsa-miR-1269b	CLIP-seq
MIRT2067775	hsa-miR-4529-3p	CLIP-seq
MIRT1230878	hsa-miR-766	CLIP-seq
MIRT2067758	hsa-miR-942	CLIP-seq
MIRT2592825	hsa-miR-4279	CLIP-seq
MIRT2592826	hsa-miR-1204	CLIP-seq
MIRT2067759	hsa-miR-1205	CLIP-seq
MIRT2592827	hsa-miR-1224-3p	CLIP-seq
MIRT2592828	hsa-miR-1247	CLIP-seq
MIRT2592829	hsa-miR-1260	CLIP-seq
MIRT2592830	hsa-miR-1260b	CLIP-seq
MIRT2067760	hsa-miR-1269	CLIP-seq
MIRT2067761	hsa-miR-1269b	CLIP-seq
MIRT2592831	hsa-miR-1273d	CLIP-seq
MIRT2592832	hsa-miR-1280	CLIP-seq
MIRT2592833	hsa-miR-1285	CLIP-seq
MIRT2067762	hsa-miR-1288	CLIP-seq
MIRT2592834	hsa-miR-1299	CLIP-seq
MIRT2592835	hsa-miR-1470	CLIP-seq
MIRT2592836	hsa-miR-182	CLIP-seq
MIRT2592837	hsa-miR-186	CLIP-seq
MIRT2592838	hsa-miR-194	CLIP-seq
MIRT1230794	hsa-miR-216a	CLIP-seq
MIRT1230833	hsa-miR-3117-5p	CLIP-seq
MIRT2592839	hsa-miR-3124-3p	CLIP-seq
MIRT2592840	hsa-miR-3127-3p	CLIP-seq
MIRT2592841	hsa-miR-3130-3p	CLIP-seq
MIRT2295202	hsa-miR-3133	CLIP-seq
MIRT2592842	hsa-miR-3170	CLIP-seq
MIRT2592843	hsa-miR-3180-5p	CLIP-seq
MIRT2295204	hsa-miR-3182	CLIP-seq
MIRT2592844	hsa-miR-3187-5p	CLIP-seq
MIRT2592845	hsa-miR-326	CLIP-seq
MIRT2592846	hsa-miR-329	CLIP-seq
MIRT2592847	hsa-miR-330-5p	CLIP-seq
MIRT2067768	hsa-miR-3612	CLIP-seq
MIRT2592848	hsa-miR-362-3p	CLIP-seq
MIRT2592849	hsa-miR-3646	CLIP-seq
MIRT2592850	hsa-miR-3653	CLIP-seq
MIRT2592851	hsa-miR-3662	CLIP-seq
MIRT2067769	hsa-miR-3685	CLIP-seq
MIRT2592852	hsa-miR-369-3p	CLIP-seq
MIRT2592853	hsa-miR-374a	CLIP-seq
MIRT2592854	hsa-miR-374b	CLIP-seq
MIRT2592855	hsa-miR-378g	CLIP-seq
MIRT2592856	hsa-miR-3941	CLIP-seq
MIRT2592857	hsa-miR-3976	CLIP-seq
MIRT2067771	hsa-miR-4269	CLIP-seq
MIRT2592825	hsa-miR-4279	CLIP-seq
MIRT2592858	hsa-miR-4286	CLIP-seq
MIRT2592859	hsa-miR-4293	CLIP-seq
MIRT2592860	hsa-miR-4314	CLIP-seq
MIRT2592861	hsa-miR-4325	CLIP-seq
MIRT2067772	hsa-miR-4443	CLIP-seq
MIRT2592862	hsa-miR-4469	CLIP-seq
MIRT2295220	hsa-miR-4470	CLIP-seq
MIRT2592863	hsa-miR-4486	CLIP-seq
MIRT2067773	hsa-miR-4515	CLIP-seq
MIRT2067775	hsa-miR-4529-3p	CLIP-seq
MIRT2592864	hsa-miR-4640-3p	CLIP-seq
MIRT2592865	hsa-miR-4667-3p	CLIP-seq
MIRT2067777	hsa-miR-4687-3p	CLIP-seq
MIRT2592866	hsa-miR-4691-3p	CLIP-seq
MIRT2067778	hsa-miR-4708-3p	CLIP-seq
MIRT2067780	hsa-miR-4740-5p	CLIP-seq
MIRT2592867	hsa-miR-4768-5p	CLIP-seq
MIRT2592868	hsa-miR-4793-3p	CLIP-seq
MIRT2067782	hsa-miR-485-5p	CLIP-seq
MIRT2592869	hsa-miR-495	CLIP-seq
MIRT2592870	hsa-miR-520a-5p	CLIP-seq
MIRT2592871	hsa-miR-525-5p	CLIP-seq
MIRT2592872	hsa-miR-544	CLIP-seq
MIRT2592873	hsa-miR-548a-3p	CLIP-seq
MIRT2592874	hsa-miR-548a-5p	CLIP-seq
MIRT2592875	hsa-miR-548ab	CLIP-seq
MIRT2592876	hsa-miR-548ak	CLIP-seq
MIRT2295238	hsa-miR-548b-3p	CLIP-seq
MIRT2592877	hsa-miR-548b-5p	CLIP-seq
MIRT2592878	hsa-miR-548c-5p	CLIP-seq
MIRT2592879	hsa-miR-548d-5p	CLIP-seq
MIRT2592880	hsa-miR-548e	CLIP-seq
MIRT2592881	hsa-miR-548f	CLIP-seq
MIRT2592882	hsa-miR-548h	CLIP-seq
MIRT2592883	hsa-miR-548i	CLIP-seq
MIRT2592884	hsa-miR-548j	CLIP-seq
MIRT2592885	hsa-miR-548w	CLIP-seq
MIRT2592886	hsa-miR-548y	CLIP-seq
MIRT2592887	hsa-miR-559	CLIP-seq
MIRT2592888	hsa-miR-568	CLIP-seq
MIRT2592889	hsa-miR-570	CLIP-seq
MIRT2067784	hsa-miR-603	CLIP-seq
MIRT2592890	hsa-miR-612	CLIP-seq
MIRT2592891	hsa-miR-642a	CLIP-seq
MIRT2067787	hsa-miR-650	CLIP-seq
MIRT1230878	hsa-miR-766	CLIP-seq
MIRT2592892	hsa-miR-875-3p	CLIP-seq
MIRT2067758	hsa-miR-942	CLIP-seq
MIRT2592826	hsa-miR-1204	CLIP-seq
MIRT2067759	hsa-miR-1205	CLIP-seq
MIRT2592827	hsa-miR-1224-3p	CLIP-seq
MIRT2592828	hsa-miR-1247	CLIP-seq
MIRT2592829	hsa-miR-1260	CLIP-seq
MIRT2592830	hsa-miR-1260b	CLIP-seq
MIRT2067760	hsa-miR-1269	CLIP-seq
MIRT2067761	hsa-miR-1269b	CLIP-seq
MIRT2592831	hsa-miR-1273d	CLIP-seq
MIRT2592832	hsa-miR-1280	CLIP-seq
MIRT2067762	hsa-miR-1288	CLIP-seq
MIRT2592834	hsa-miR-1299	CLIP-seq
MIRT2592835	hsa-miR-1470	CLIP-seq
MIRT2592837	hsa-miR-186	CLIP-seq
MIRT2592838	hsa-miR-194	CLIP-seq
MIRT1230833	hsa-miR-3117-5p	CLIP-seq
MIRT2592841	hsa-miR-3130-3p	CLIP-seq
MIRT2295202	hsa-miR-3133	CLIP-seq
MIRT2687832	hsa-miR-3140-3p	CLIP-seq
MIRT2592843	hsa-miR-3180-5p	CLIP-seq
MIRT2592845	hsa-miR-326	CLIP-seq
MIRT2592846	hsa-miR-329	CLIP-seq
MIRT2592847	hsa-miR-330-5p	CLIP-seq
MIRT2067768	hsa-miR-3612	CLIP-seq
MIRT2592848	hsa-miR-362-3p	CLIP-seq
MIRT2067769	hsa-miR-3685	CLIP-seq
MIRT2592856	hsa-miR-3941	CLIP-seq
MIRT2067771	hsa-miR-4269	CLIP-seq
MIRT2592825	hsa-miR-4279	CLIP-seq
MIRT2592858	hsa-miR-4286	CLIP-seq
MIRT2592859	hsa-miR-4293	CLIP-seq
MIRT2592861	hsa-miR-4325	CLIP-seq
MIRT2067772	hsa-miR-4443	CLIP-seq
MIRT2592862	hsa-miR-4469	CLIP-seq
MIRT2067773	hsa-miR-4515	CLIP-seq
MIRT2067775	hsa-miR-4529-3p	CLIP-seq
MIRT2592864	hsa-miR-4640-3p	CLIP-seq
MIRT2592865	hsa-miR-4667-3p	CLIP-seq
MIRT2067777	hsa-miR-4687-3p	CLIP-seq
MIRT2592866	hsa-miR-4691-3p	CLIP-seq
MIRT2067778	hsa-miR-4708-3p	CLIP-seq
MIRT2067780	hsa-miR-4740-5p	CLIP-seq
MIRT2592867	hsa-miR-4768-5p	CLIP-seq
MIRT2687833	hsa-miR-4777-5p	CLIP-seq
MIRT2592868	hsa-miR-4793-3p	CLIP-seq
MIRT2067782	hsa-miR-485-5p	CLIP-seq
MIRT2592869	hsa-miR-495	CLIP-seq
MIRT2687834	hsa-miR-518d-5p	CLIP-seq
MIRT2687835	hsa-miR-519b-5p	CLIP-seq
MIRT2687836	hsa-miR-519c-5p	CLIP-seq
MIRT2592870	hsa-miR-520a-5p	CLIP-seq
MIRT2687837	hsa-miR-520c-5p	CLIP-seq
MIRT2592871	hsa-miR-525-5p	CLIP-seq
MIRT2687838	hsa-miR-526a	CLIP-seq
MIRT2592872	hsa-miR-544	CLIP-seq
MIRT2295238	hsa-miR-548b-3p	CLIP-seq
MIRT2592889	hsa-miR-570	CLIP-seq
MIRT2067784	hsa-miR-603	CLIP-seq
MIRT2067787	hsa-miR-650	CLIP-seq
MIRT1230878	hsa-miR-766	CLIP-seq
MIRT2592892	hsa-miR-875-3p	CLIP-seq
MIRT2067789	hsa-miR-924	CLIP-seq
MIRT2067758	hsa-miR-942	CLIP-seq

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000118	Component	Histone deacetylase complex	IBA
GO:0000118	Component	Histone deacetylase complex	IDA	15325272
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	15325272
GO:0003677	Function	DNA binding	IEA
GO:0003682	Function	Chromatin binding	IBA
GO:0003682	Function	Chromatin binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 29892012, 31515488, 32296183, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006325	Process	Chromatin organization	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:1990391	Component	DNA repair complex	IDA	24217620

MIM	HGNC	e!Ensembl
608325	24156	ENSG00000135365

Q96BD5

Protein name

PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)

Protein function

Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on

PDB

2PUY , 2YQL

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00628	PHD	490 → 535	PHD-finger	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in brain (PubMed:31649809). Expressed at lower level in other tissues, including heart, kidney, liver, lung and skeletal muscle (PubMed:31649809). Abundantly expressed in fetal brain (PubMed:31649809). {ECO:0000269|Pub

Sequence

MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRK
NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQ
KTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNL
QTSSKVTGPGAEAVQIVAKNTVTLVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVA
QNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFPM
AQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPKRE
ENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNST
MHPGTRKRGRPPKYNAVLGFGALTPTSPQSSHPDSPENEKTETTFTFPAPVQPVSLPSPT
STDGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKE
EAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCMEM
KNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNGPDCTPPANAATSTP
APSPSSQSCTANCNQGEETK

Sequence length

680

Interactions

View interactions

	Reactome
			HDACs deacetylate histones Factors involved in megakaryocyte development and platelet production

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (3)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures	Pathogenic; Likely pathogenic	rs2135465689, rs2135936249, rs2136047144, rs2134991780, rs2504489983, rs2495614521, rs2497897075, rs2497635596, rs2504765197, rs761575760, rs1554988946, rs1565138763, rs1591102099, rs1591407315, rs1591092743, rs2092369866 View all (1 more)	RCV001775317 RCV001807961 RCV002052210 RCV002086745 RCV002287615 View all (11 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Intellectual disability	Likely pathogenic; Pathogenic	rs1565138763	RCV000760234	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
PHF21A-related disorder	Likely pathogenic; Pathogenic	rs2498652640	RCV003404026	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (13)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism spectrum disorder	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, OVARIAN EPITHELIAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHROMOSOME 11P11.2 DELETION SYNDROME	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COMPLEX NEURODEVELOPMENTAL DISORDER	—	ClinGen, GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GOUT	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTROPHIC CARDIOMYOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POTOCKI-SHAFFER SYNDROME	—	GWAS catalog, Orphanet GWAS catalog, Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (47)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma of prostate	Prostate adenocarcinoma	BEFREE	30910347		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anemia	Anemia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Aniridia	Aniridia	BEFREE	27124303		★★★★★ ★☆☆☆☆ Found in Text Mining only
Aniridia cerebellar ataxia mental deficiency	Aniridia-cerebellar ataxia-intellectual disability syndrome	Pubtator	27124303	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	30487643, 31649809	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	30487643, 31649809		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	Pubtator	31649809	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Brachycephaly	Brachycephaly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	CTD_human_DG	28811376		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chromosome 11p11.2 Deletion Syndrome	11p11.2 Deletion Syndrome	BEFREE	22770980, 23239541, 28127865, 28571721, 30487643		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chromosome 11p11.2 Deletion Syndrome	11p11.2 Deletion Syndrome	ORPHANET_DG	22770980		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chromosome 11p11.2 Deletion Syndrome	11p11.2 Deletion Syndrome	GENOMICS_ENGLAND_DG	30487643		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	38167072	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Abnormalities	Congenital abnormalities	Pubtator	36555772	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Epicanthus	Congenital Epicanthus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Craniofacial Abnormalities	Craniofacial abnormalities	Pubtator	28571721, 30487643, 31649809, 36555772	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Defect of skull ossification	Defect Of Skull Ossification	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	31523167		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	Pubtator	30487643, 31649809, 36555772	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	29362722		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	29362722	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	BEFREE	26333423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypothyroidism	Hypothyroidism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	22770980, 23239541, 27124303, 28127865, 28571721, 30487643, 31649809		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual Disability	Intellectual developmental disorder	Pubtator	27124303, 28571721, 30487643, 31649809, 36555772	Associate	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual Disability	Mental retardation	GENOMICS_ENGLAND_DG	30487643		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual Disability	Mental retardation	HPO_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Malignant neoplasm of prostate	Prostate cancer	BEFREE	30910347		★★★★★ ★☆☆☆☆ Found in Text Mining only
Micrognathism	Micrognathism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30910347		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nephroblastoma	Nephroblastoma	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodevelopmental Disorders	Neurodevelopmental Disorders	BEFREE	26077434		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nystagmus	Nystagmus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	31523167	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
PARIETAL FORAMINA	Parietal Foramina	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
PEELING SKIN SYNDROME	Peeling Skin Syndrome	GENOMICS_ENGLAND_DG	30487643		★★★★★ ★☆☆☆☆ Found in Text Mining only
Penis agenesis	Penis Agenesis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Pervasive Development Disorder	Autism spectrum disorder	BEFREE	30487643, 31649809		★★★★★ ★☆☆☆☆ Found in Text Mining only
Potocki-Shaffer syndrome	Potocki-Shaffer Syndrome	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate carcinoma	Prostate cancer	BEFREE	30910347		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pseudohypoparathyroidism	Pseudohypoparathyroidism	Pubtator	36555772	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Strabismus	Strabismus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Syndactyly	Syndactyly	BEFREE	31649809		★★★★★ ★☆☆☆☆ Found in Text Mining only
Syndactyly	Syndactyly	Pubtator	31649809	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Systemic Scleroderma	Scleroderma	GENOMICS_ENGLAND_DG	30487643		★★★★★ ★☆☆☆☆ Found in Text Mining only

PHF21A (PHD finger protein 21A)