Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	51283
Gene name	Bifunctional apoptosis regulator
Gene symbol	BFAR
Synonyms (NCBI Gene)	BARRNF47
Chromosome	16
Chromosome location	16p13.12

317

Show/Hide all (317)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020378	hsa-miR-29c-3p	Sequencing	20371350
MIRT027003	hsa-miR-103a-3p	Sequencing	20371350
MIRT027411	hsa-miR-98-5p	Microarray	19088304
MIRT031448	hsa-miR-16-5p	Sequencing	20371350
MIRT049808	hsa-miR-92a-3p	CLASH	23622248
MIRT724500	hsa-miR-6823-5p	HITS-CLIP	19536157
MIRT724499	hsa-miR-4635	HITS-CLIP	19536157
MIRT724498	hsa-miR-4680-5p	HITS-CLIP	19536157
MIRT724497	hsa-miR-1293	HITS-CLIP	19536157
MIRT724496	hsa-miR-4483	HITS-CLIP	19536157
MIRT724495	hsa-miR-6801-5p	HITS-CLIP	19536157
MIRT724494	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT724493	hsa-miR-7158-3p	HITS-CLIP	19536157
MIRT724492	hsa-miR-203b-3p	HITS-CLIP	19536157
MIRT724491	hsa-miR-5587-5p	HITS-CLIP	19536157
MIRT734001	hsa-miR-424-5p	Immunohistochemistry (IHC)Luciferase reporter assayqRT-PCRWestern blotting	32483702
MIRT724500	hsa-miR-6823-5p	HITS-CLIP	19536157
MIRT724499	hsa-miR-4635	HITS-CLIP	19536157
MIRT724498	hsa-miR-4680-5p	HITS-CLIP	19536157
MIRT724497	hsa-miR-1293	HITS-CLIP	19536157
MIRT724496	hsa-miR-4483	HITS-CLIP	19536157
MIRT724495	hsa-miR-6801-5p	HITS-CLIP	19536157
MIRT724494	hsa-miR-323a-5p	HITS-CLIP	19536157
MIRT724493	hsa-miR-7158-3p	HITS-CLIP	19536157
MIRT724492	hsa-miR-203b-3p	HITS-CLIP	19536157
MIRT724491	hsa-miR-5587-5p	HITS-CLIP	19536157
MIRT821123	hsa-miR-1252	CLIP-seq
MIRT821124	hsa-miR-1281	CLIP-seq
MIRT821125	hsa-miR-1297	CLIP-seq
MIRT821126	hsa-miR-1343	CLIP-seq
MIRT821127	hsa-miR-15a	CLIP-seq
MIRT821128	hsa-miR-15b	CLIP-seq
MIRT821129	hsa-miR-16	CLIP-seq
MIRT821130	hsa-miR-195	CLIP-seq
MIRT821131	hsa-miR-26a	CLIP-seq
MIRT821132	hsa-miR-26b	CLIP-seq
MIRT821133	hsa-miR-3065-3p	CLIP-seq
MIRT821134	hsa-miR-3202	CLIP-seq
MIRT821135	hsa-miR-330-3p	CLIP-seq
MIRT821136	hsa-miR-3616-5p	CLIP-seq
MIRT821137	hsa-miR-3647-5p	CLIP-seq
MIRT737583	hsa-miR-370	CLIP-seq
MIRT737582	hsa-miR-377	CLIP-seq
MIRT821138	hsa-miR-3929	CLIP-seq
MIRT821139	hsa-miR-3937	CLIP-seq
MIRT821140	hsa-miR-424	CLIP-seq
MIRT821141	hsa-miR-4419b	CLIP-seq
MIRT821142	hsa-miR-4465	CLIP-seq
MIRT821143	hsa-miR-4478	CLIP-seq
MIRT821144	hsa-miR-4533	CLIP-seq
MIRT821145	hsa-miR-4659a-3p	CLIP-seq
MIRT821146	hsa-miR-4659b-3p	CLIP-seq
MIRT821147	hsa-miR-4753-5p	CLIP-seq
MIRT821148	hsa-miR-4795-5p	CLIP-seq
MIRT821149	hsa-miR-497	CLIP-seq
MIRT821150	hsa-miR-498	CLIP-seq
MIRT821151	hsa-miR-519a	CLIP-seq
MIRT821152	hsa-miR-519b-3p	CLIP-seq
MIRT821153	hsa-miR-519c-3p	CLIP-seq
MIRT821154	hsa-miR-520d-5p	CLIP-seq
MIRT821155	hsa-miR-524-5p	CLIP-seq
MIRT821156	hsa-miR-573	CLIP-seq
MIRT821157	hsa-miR-642a	CLIP-seq
MIRT737581	hsa-miR-1228	CLIP-seq
MIRT737584	hsa-miR-342-3p	CLIP-seq
MIRT737583	hsa-miR-370	CLIP-seq
MIRT737582	hsa-miR-377	CLIP-seq
MIRT737581	hsa-miR-1228	CLIP-seq
MIRT1942688	hsa-miR-1237	CLIP-seq
MIRT821123	hsa-miR-1252	CLIP-seq
MIRT821124	hsa-miR-1281	CLIP-seq
MIRT821126	hsa-miR-1343	CLIP-seq
MIRT1942689	hsa-miR-1470	CLIP-seq
MIRT1942690	hsa-miR-197	CLIP-seq
MIRT1942691	hsa-miR-2110	CLIP-seq
MIRT1942692	hsa-miR-2964a-5p	CLIP-seq
MIRT1942693	hsa-miR-3149	CLIP-seq
MIRT1942694	hsa-miR-3150a-3p	CLIP-seq
MIRT1942695	hsa-miR-3175	CLIP-seq
MIRT1942696	hsa-miR-3199	CLIP-seq
MIRT737584	hsa-miR-342-3p	CLIP-seq
MIRT1942697	hsa-miR-3614-5p	CLIP-seq
MIRT821136	hsa-miR-3616-5p	CLIP-seq
MIRT821137	hsa-miR-3647-5p	CLIP-seq
MIRT1942698	hsa-miR-3664-5p	CLIP-seq
MIRT1942699	hsa-miR-3688-5p	CLIP-seq
MIRT737583	hsa-miR-370	CLIP-seq
MIRT1942700	hsa-miR-3913-3p	CLIP-seq
MIRT821138	hsa-miR-3929	CLIP-seq
MIRT1942701	hsa-miR-3940-5p	CLIP-seq
MIRT1942702	hsa-miR-4287	CLIP-seq
MIRT821141	hsa-miR-4419b	CLIP-seq
MIRT1942703	hsa-miR-4427	CLIP-seq
MIRT1942704	hsa-miR-4469	CLIP-seq
MIRT821143	hsa-miR-4478	CLIP-seq
MIRT1942705	hsa-miR-4502	CLIP-seq
MIRT1942706	hsa-miR-4507	CLIP-seq
MIRT821144	hsa-miR-4533	CLIP-seq
MIRT1942707	hsa-miR-4652-5p	CLIP-seq
MIRT1942708	hsa-miR-4667-3p	CLIP-seq
MIRT1942709	hsa-miR-4680-3p	CLIP-seq
MIRT1942710	hsa-miR-4685-3p	CLIP-seq
MIRT1942711	hsa-miR-4714-5p	CLIP-seq
MIRT1942712	hsa-miR-4716-5p	CLIP-seq
MIRT1942713	hsa-miR-4728-5p	CLIP-seq
MIRT1942714	hsa-miR-4735-5p	CLIP-seq
MIRT1942715	hsa-miR-4740-5p	CLIP-seq
MIRT821147	hsa-miR-4753-5p	CLIP-seq
MIRT1942716	hsa-miR-4762-3p	CLIP-seq
MIRT1942717	hsa-miR-4772-3p	CLIP-seq
MIRT1942718	hsa-miR-4775	CLIP-seq
MIRT1942719	hsa-miR-4781-3p	CLIP-seq
MIRT821148	hsa-miR-4795-5p	CLIP-seq
MIRT1942720	hsa-miR-489	CLIP-seq
MIRT1942721	hsa-miR-5096	CLIP-seq
MIRT821151	hsa-miR-519a	CLIP-seq
MIRT821152	hsa-miR-519b-3p	CLIP-seq
MIRT821153	hsa-miR-519c-3p	CLIP-seq
MIRT821154	hsa-miR-520d-5p	CLIP-seq
MIRT821155	hsa-miR-524-5p	CLIP-seq
MIRT821156	hsa-miR-573	CLIP-seq
MIRT1942722	hsa-miR-590-3p	CLIP-seq
MIRT1942723	hsa-miR-629	CLIP-seq
MIRT1942724	hsa-miR-939	CLIP-seq
MIRT2181485	hsa-miR-1206	CLIP-seq
MIRT2181486	hsa-miR-1227	CLIP-seq
MIRT821123	hsa-miR-1252	CLIP-seq
MIRT2181487	hsa-miR-127-3p	CLIP-seq
MIRT821124	hsa-miR-1281	CLIP-seq
MIRT2181488	hsa-miR-1294	CLIP-seq
MIRT821125	hsa-miR-1297	CLIP-seq
MIRT821126	hsa-miR-1343	CLIP-seq
MIRT2181489	hsa-miR-143	CLIP-seq
MIRT1942690	hsa-miR-197	CLIP-seq
MIRT1942691	hsa-miR-2110	CLIP-seq
MIRT2181490	hsa-miR-223	CLIP-seq
MIRT821131	hsa-miR-26a	CLIP-seq
MIRT821132	hsa-miR-26b	CLIP-seq
MIRT1942694	hsa-miR-3150a-3p	CLIP-seq
MIRT1942695	hsa-miR-3175	CLIP-seq
MIRT2181491	hsa-miR-3184	CLIP-seq
MIRT1942696	hsa-miR-3199	CLIP-seq
MIRT821134	hsa-miR-3202	CLIP-seq
MIRT1942697	hsa-miR-3614-5p	CLIP-seq
MIRT821136	hsa-miR-3616-5p	CLIP-seq
MIRT821137	hsa-miR-3647-5p	CLIP-seq
MIRT2181492	hsa-miR-3663-5p	CLIP-seq
MIRT1942699	hsa-miR-3688-5p	CLIP-seq
MIRT2181493	hsa-miR-3691-3p	CLIP-seq
MIRT737582	hsa-miR-377	CLIP-seq
MIRT1942700	hsa-miR-3913-3p	CLIP-seq
MIRT821138	hsa-miR-3929	CLIP-seq
MIRT821139	hsa-miR-3937	CLIP-seq
MIRT2181494	hsa-miR-423-5p	CLIP-seq
MIRT821141	hsa-miR-4419b	CLIP-seq
MIRT2181495	hsa-miR-4420	CLIP-seq
MIRT2181496	hsa-miR-4421	CLIP-seq
MIRT2181497	hsa-miR-4438	CLIP-seq
MIRT821142	hsa-miR-4465	CLIP-seq
MIRT821143	hsa-miR-4478	CLIP-seq
MIRT821144	hsa-miR-4533	CLIP-seq
MIRT2181498	hsa-miR-455-5p	CLIP-seq
MIRT1942707	hsa-miR-4652-5p	CLIP-seq
MIRT2181499	hsa-miR-4697-3p	CLIP-seq
MIRT2181500	hsa-miR-4704-3p	CLIP-seq
MIRT2181501	hsa-miR-4716-3p	CLIP-seq
MIRT1942712	hsa-miR-4716-5p	CLIP-seq
MIRT2181502	hsa-miR-4723-5p	CLIP-seq
MIRT1942713	hsa-miR-4728-5p	CLIP-seq
MIRT1942714	hsa-miR-4735-5p	CLIP-seq
MIRT1942715	hsa-miR-4740-5p	CLIP-seq
MIRT2181503	hsa-miR-4770	CLIP-seq
MIRT1942718	hsa-miR-4775	CLIP-seq
MIRT1942719	hsa-miR-4781-3p	CLIP-seq
MIRT2181504	hsa-miR-4790-3p	CLIP-seq
MIRT821148	hsa-miR-4795-5p	CLIP-seq
MIRT1942720	hsa-miR-489	CLIP-seq
MIRT2181505	hsa-miR-490-5p	CLIP-seq
MIRT2181506	hsa-miR-5095	CLIP-seq
MIRT1942721	hsa-miR-5096	CLIP-seq
MIRT821151	hsa-miR-519a	CLIP-seq
MIRT821152	hsa-miR-519b-3p	CLIP-seq
MIRT821153	hsa-miR-519c-3p	CLIP-seq
MIRT2181507	hsa-miR-552	CLIP-seq
MIRT2181508	hsa-miR-562	CLIP-seq
MIRT821156	hsa-miR-573	CLIP-seq
MIRT1942722	hsa-miR-590-3p	CLIP-seq
MIRT1942724	hsa-miR-939	CLIP-seq
MIRT1942693	hsa-miR-3149	CLIP-seq
MIRT1942697	hsa-miR-3614-5p	CLIP-seq
MIRT821136	hsa-miR-3616-5p	CLIP-seq
MIRT821137	hsa-miR-3647-5p	CLIP-seq
MIRT821138	hsa-miR-3929	CLIP-seq
MIRT821141	hsa-miR-4419b	CLIP-seq
MIRT821143	hsa-miR-4478	CLIP-seq
MIRT821145	hsa-miR-4659a-3p	CLIP-seq
MIRT821146	hsa-miR-4659b-3p	CLIP-seq
MIRT1942714	hsa-miR-4735-5p	CLIP-seq
MIRT1942718	hsa-miR-4775	CLIP-seq
MIRT821148	hsa-miR-4795-5p	CLIP-seq
MIRT2384773	hsa-miR-4798-5p	CLIP-seq
MIRT2181506	hsa-miR-5095	CLIP-seq
MIRT821151	hsa-miR-519a	CLIP-seq
MIRT821152	hsa-miR-519b-3p	CLIP-seq
MIRT821153	hsa-miR-519c-3p	CLIP-seq
MIRT821156	hsa-miR-573	CLIP-seq
MIRT1942722	hsa-miR-590-3p	CLIP-seq
MIRT2181486	hsa-miR-1227	CLIP-seq
MIRT821124	hsa-miR-1281	CLIP-seq
MIRT821126	hsa-miR-1343	CLIP-seq
MIRT1942689	hsa-miR-1470	CLIP-seq
MIRT2484912	hsa-miR-219-2-3p	CLIP-seq
MIRT2484913	hsa-miR-3121-5p	CLIP-seq
MIRT1942693	hsa-miR-3149	CLIP-seq
MIRT1942697	hsa-miR-3614-5p	CLIP-seq
MIRT821136	hsa-miR-3616-5p	CLIP-seq
MIRT2484914	hsa-miR-3617	CLIP-seq
MIRT821137	hsa-miR-3647-5p	CLIP-seq
MIRT1942698	hsa-miR-3664-5p	CLIP-seq
MIRT2181493	hsa-miR-3691-3p	CLIP-seq
MIRT821138	hsa-miR-3929	CLIP-seq
MIRT821139	hsa-miR-3937	CLIP-seq
MIRT1942701	hsa-miR-3940-5p	CLIP-seq
MIRT2484915	hsa-miR-411	CLIP-seq
MIRT1942702	hsa-miR-4287	CLIP-seq
MIRT821141	hsa-miR-4419b	CLIP-seq
MIRT1942703	hsa-miR-4427	CLIP-seq
MIRT2484916	hsa-miR-4452	CLIP-seq
MIRT1942704	hsa-miR-4469	CLIP-seq
MIRT821143	hsa-miR-4478	CLIP-seq
MIRT1942706	hsa-miR-4507	CLIP-seq
MIRT2181498	hsa-miR-455-5p	CLIP-seq
MIRT821145	hsa-miR-4659a-3p	CLIP-seq
MIRT821146	hsa-miR-4659b-3p	CLIP-seq
MIRT1942708	hsa-miR-4667-3p	CLIP-seq
MIRT1942709	hsa-miR-4680-3p	CLIP-seq
MIRT1942710	hsa-miR-4685-3p	CLIP-seq
MIRT1942711	hsa-miR-4714-5p	CLIP-seq
MIRT1942714	hsa-miR-4735-5p	CLIP-seq
MIRT1942717	hsa-miR-4772-3p	CLIP-seq
MIRT1942718	hsa-miR-4775	CLIP-seq
MIRT821148	hsa-miR-4795-5p	CLIP-seq
MIRT2384773	hsa-miR-4798-5p	CLIP-seq
MIRT2484917	hsa-miR-500a	CLIP-seq
MIRT2484918	hsa-miR-501-5p	CLIP-seq
MIRT2181506	hsa-miR-5095	CLIP-seq
MIRT821151	hsa-miR-519a	CLIP-seq
MIRT821152	hsa-miR-519b-3p	CLIP-seq
MIRT821153	hsa-miR-519c-3p	CLIP-seq
MIRT2181507	hsa-miR-552	CLIP-seq
MIRT2181508	hsa-miR-562	CLIP-seq
MIRT821156	hsa-miR-573	CLIP-seq
MIRT1942722	hsa-miR-590-3p	CLIP-seq
MIRT2484919	hsa-miR-592	CLIP-seq
MIRT2484920	hsa-miR-597	CLIP-seq
MIRT1942723	hsa-miR-629	CLIP-seq
MIRT2484921	hsa-miR-641	CLIP-seq
MIRT2484922	hsa-miR-653	CLIP-seq
MIRT2181486	hsa-miR-1227	CLIP-seq
MIRT821124	hsa-miR-1281	CLIP-seq
MIRT2181488	hsa-miR-1294	CLIP-seq
MIRT821126	hsa-miR-1343	CLIP-seq
MIRT1942689	hsa-miR-1470	CLIP-seq
MIRT2675952	hsa-miR-2114	CLIP-seq
MIRT2484912	hsa-miR-219-2-3p	CLIP-seq
MIRT2484913	hsa-miR-3121-5p	CLIP-seq
MIRT1942693	hsa-miR-3149	CLIP-seq
MIRT2675953	hsa-miR-339-5p	CLIP-seq
MIRT1942697	hsa-miR-3614-5p	CLIP-seq
MIRT821136	hsa-miR-3616-5p	CLIP-seq
MIRT2484914	hsa-miR-3617	CLIP-seq
MIRT821137	hsa-miR-3647-5p	CLIP-seq
MIRT2675954	hsa-miR-3652	CLIP-seq
MIRT1942698	hsa-miR-3664-5p	CLIP-seq
MIRT2181493	hsa-miR-3691-3p	CLIP-seq
MIRT2675955	hsa-miR-3915	CLIP-seq
MIRT2675956	hsa-miR-3928	CLIP-seq
MIRT821138	hsa-miR-3929	CLIP-seq
MIRT821139	hsa-miR-3937	CLIP-seq
MIRT1942701	hsa-miR-3940-5p	CLIP-seq
MIRT2484915	hsa-miR-411	CLIP-seq
MIRT1942702	hsa-miR-4287	CLIP-seq
MIRT2675957	hsa-miR-4316	CLIP-seq
MIRT821141	hsa-miR-4419b	CLIP-seq
MIRT1942703	hsa-miR-4427	CLIP-seq
MIRT2675958	hsa-miR-4430	CLIP-seq
MIRT2484916	hsa-miR-4452	CLIP-seq
MIRT1942704	hsa-miR-4469	CLIP-seq
MIRT2675959	hsa-miR-4476	CLIP-seq
MIRT821143	hsa-miR-4478	CLIP-seq
MIRT2675960	hsa-miR-4505	CLIP-seq
MIRT1942706	hsa-miR-4507	CLIP-seq
MIRT2181498	hsa-miR-455-5p	CLIP-seq
MIRT821145	hsa-miR-4659a-3p	CLIP-seq
MIRT821146	hsa-miR-4659b-3p	CLIP-seq
MIRT1942708	hsa-miR-4667-3p	CLIP-seq
MIRT2675961	hsa-miR-4677-3p	CLIP-seq
MIRT1942709	hsa-miR-4680-3p	CLIP-seq
MIRT1942710	hsa-miR-4685-3p	CLIP-seq
MIRT1942711	hsa-miR-4714-5p	CLIP-seq
MIRT1942714	hsa-miR-4735-5p	CLIP-seq
MIRT1942717	hsa-miR-4772-3p	CLIP-seq
MIRT1942718	hsa-miR-4775	CLIP-seq
MIRT821148	hsa-miR-4795-5p	CLIP-seq
MIRT2484917	hsa-miR-500a	CLIP-seq
MIRT2484918	hsa-miR-501-5p	CLIP-seq
MIRT2181506	hsa-miR-5095	CLIP-seq
MIRT821151	hsa-miR-519a	CLIP-seq
MIRT821152	hsa-miR-519b-3p	CLIP-seq
MIRT821153	hsa-miR-519c-3p	CLIP-seq
MIRT2181507	hsa-miR-552	CLIP-seq
MIRT2181508	hsa-miR-562	CLIP-seq
MIRT821156	hsa-miR-573	CLIP-seq
MIRT1942722	hsa-miR-590-3p	CLIP-seq
MIRT1942723	hsa-miR-629	CLIP-seq
MIRT2484921	hsa-miR-641	CLIP-seq
MIRT2484922	hsa-miR-653	CLIP-seq

Show/Hide all (28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	IDA	21068390
GO:0005515	Function	Protein binding	IPI	21068390, 32296183, 32814053
GO:0005783	Component	Endoplasmic reticulum	IDA	21068390
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	NAS	21068390
GO:0005886	Component	Plasma membrane	NAS	10716992
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IDA	21068390
GO:0006915	Process	Apoptotic process	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016020	Component	Membrane	IDA	10716992
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	10716992
GO:0036498	Process	IRE1-mediated unfolded protein response	IMP	28128204
GO:0036498	Process	IRE1-mediated unfolded protein response	TAS	22013210
GO:0043066	Process	Negative regulation of apoptotic process	IDA	10716992
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	21068390
GO:0046872	Function	Metal ion binding	IEA
GO:0051865	Process	Protein autoubiquitination	IDA	21068390
GO:0061630	Function	Ubiquitin protein ligase activity	IBA
GO:0061630	Function	Ubiquitin protein ligase activity	IDA	21068390
GO:0070534	Process	Protein K63-linked ubiquitination	IDA	21068390
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	21068390
GO:0089720	Function	Caspase binding	IDA	10716992
GO:1903895	Process	Negative regulation of IRE1-mediated unfolded protein response	IDA	19328063
GO:1903895	Process	Negative regulation of IRE1-mediated unfolded protein response	IMP	21068390

MIM	HGNC	e!Ensembl
619516	17613	ENSG00000103429

Q9NZS9

Protein name

Bifunctional apoptosis regulator (EC 2.3.2.27) (RING finger protein 47)

Protein function

Membrane-bound E3 ubiquitin ligase that plays a role in several processes including apoptosis regulation or reticulum endoplasmic stress (PubMed:14502241, PubMed:21068390). Has anti-apoptotic activity, both for apoptosis triggered via death-rece

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15227	zf-C3HC4_4	34 → 73		Domain
PF00536	SAM_1	180 → 247	SAM domain (Sterile alpha motif)	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen. {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}.

Sequence

MEEPQKSYVNTMDLERDEPLKSTGPQISVSEFSCHCCYDILVNPTTLNCGHSFCRHCLAL
WWASSKKTECPECREKWEGFPKVSILLRDAIEKLFPDAIRLRFEDIQQNNDIVQSLAAFQ
KYGNDQIPLAPNTGRANQQMGGGFFSGVLTALTGVAVVLLVYHWSSRESEHDLLVHKAVA
KWTAEEVVLWLEQLGPWASLYRERFLSERVNGRLLLTLTEEEFSKTPYTIENSSHRRAIL
MELERVKALGVKPPQNLWEYKAVNPGRSLFLLYALKSSPRLSLLYLYLFDYTDTFLPFIH
TICPLQEDSSGEDIVTKLLDLKEPTWKQWREFLVKYSFLPYQLIAEFAWDWLEVHYWTSR
FLIINAMLLSVLELFSFWRIWSRSELKTVPQRMWSHFWKVSTQGLFVAMFWPLIPQFVCN
CLFYWALYFNPIINIDLVVKELRRLETQVL

Sequence length

450

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (35)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma Of Esophagus	Esophageal Cancer	BEFREE	21525435, 24025864		★★★★★ ★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Barrett esophagus	BEFREE	19920191, 30268789		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	23644527		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	31043634		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	21565989, 9709965		★★★★★ ★☆☆☆☆ Found in Text Mining only
Erythema Multiforme	Erythema	BEFREE	30467994		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	32483702	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Diseases	Heart disease	Pubtator	28711716	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Failure	Heart failure	Pubtator	28711716	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	BEFREE	31043634		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	24105372		★★★★★ ★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 1	Major Affective Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 2	Major Affective Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 4	Major Affective Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 6	Major Affective Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 7	Major Affective Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 8	Major Affective Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 9	Major Affective Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	18930786, 20940394, 21678469		★★★★★ ★☆☆☆☆ Found in Text Mining only
Manic	Manic Disorder	BEFREE	20619465		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	35563024	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Diseases	Metabolic Diseases	BEFREE	9709965		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mitral Valve Stenosis	Mitral Valve Stenosis	BEFREE	1666018		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	30467994		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	20309934		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	19121815		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	10999801, 12395215, 18346809, 21565989, 9709965		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity, Morbid	Obesity	BEFREE	18346809		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oculocerebrorenal Syndrome	Oculocerebrorenal Syndrome	BEFREE	30799246		★★★★★ ★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	BEFREE	30219060		★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral Arterial Diseases	Vascular Diseases	BEFREE	29513389		★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral arterial stenosis	Peripheral arterial stenosis	BEFREE	29513389		★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral Vascular Diseases	Vascular Diseases	BEFREE	29513389		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	27189492		★★★★★ ★☆☆☆☆ Found in Text Mining only

BFAR (bifunctional apoptosis regulator)