Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	5127
Gene name	Cyclin dependent kinase 16
Gene symbol	CDK16
Synonyms (NCBI Gene)	PCTAIREPCTAIRE1PCTGAIREPCTK1
Chromosome	X
Chromosome location	Xp11.3
Summary	The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from th

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miRTarBase ID	miRNA	Experiments	Reference
MIRT050576	hsa-miR-20a-5p	CLASH	23622248
MIRT037393	hsa-miR-744-5p	CLASH	23622248
MIRT109926	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT109929	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT109924	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT109925	hsa-miR-33a-5p	Luciferase reporter assay	27073545
MIRT109925	hsa-miR-33a-5p	Luciferase reporter assay	27073545
MIRT756131	hsa-miR-324-5p	Luciferase reporter assayWestern blottingqRT-PCRRNA pull down assay	35273726
MIRT880432	hsa-miR-1252	CLIP-seq
MIRT880433	hsa-miR-125a-3p	CLIP-seq
MIRT880434	hsa-miR-1275	CLIP-seq
MIRT880435	hsa-miR-1294	CLIP-seq
MIRT880436	hsa-miR-1324	CLIP-seq
MIRT880437	hsa-miR-24	CLIP-seq
MIRT880438	hsa-miR-2682	CLIP-seq
MIRT880439	hsa-miR-3665	CLIP-seq
MIRT880440	hsa-miR-4259	CLIP-seq
MIRT880441	hsa-miR-4269	CLIP-seq
MIRT880442	hsa-miR-4284	CLIP-seq
MIRT880443	hsa-miR-4316	CLIP-seq
MIRT880444	hsa-miR-4488	CLIP-seq
MIRT880445	hsa-miR-449c	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT880447	hsa-miR-4665-5p	CLIP-seq
MIRT880448	hsa-miR-4677-3p	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT880450	hsa-miR-4697-5p	CLIP-seq
MIRT880451	hsa-miR-4703-3p	CLIP-seq
MIRT880452	hsa-miR-4715-5p	CLIP-seq
MIRT880453	hsa-miR-4736	CLIP-seq
MIRT880454	hsa-miR-4742-5p	CLIP-seq
MIRT880455	hsa-miR-874	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT880457	hsa-miR-103b	CLIP-seq
MIRT880458	hsa-miR-1182	CLIP-seq
MIRT880459	hsa-miR-1224-3p	CLIP-seq
MIRT880433	hsa-miR-125a-3p	CLIP-seq
MIRT880434	hsa-miR-1275	CLIP-seq
MIRT880460	hsa-miR-1909	CLIP-seq
MIRT880461	hsa-miR-1915	CLIP-seq
MIRT880462	hsa-miR-1972	CLIP-seq
MIRT880463	hsa-miR-200b	CLIP-seq
MIRT880464	hsa-miR-200c	CLIP-seq
MIRT880465	hsa-miR-214	CLIP-seq
MIRT880437	hsa-miR-24	CLIP-seq
MIRT880466	hsa-miR-25	CLIP-seq
MIRT880438	hsa-miR-2682	CLIP-seq
MIRT880467	hsa-miR-296-5p	CLIP-seq
MIRT880468	hsa-miR-3151	CLIP-seq
MIRT880469	hsa-miR-3158-3p	CLIP-seq
MIRT880470	hsa-miR-3192	CLIP-seq
MIRT880471	hsa-miR-32	CLIP-seq
MIRT880472	hsa-miR-33a	CLIP-seq
MIRT880473	hsa-miR-33b	CLIP-seq
MIRT880474	hsa-miR-342-5p	CLIP-seq
MIRT880475	hsa-miR-3619-5p	CLIP-seq
MIRT880476	hsa-miR-363	CLIP-seq
MIRT880439	hsa-miR-3665	CLIP-seq
MIRT880477	hsa-miR-367	CLIP-seq
MIRT880478	hsa-miR-3682-3p	CLIP-seq
MIRT880479	hsa-miR-383	CLIP-seq
MIRT880440	hsa-miR-4259	CLIP-seq
MIRT880441	hsa-miR-4269	CLIP-seq
MIRT880442	hsa-miR-4284	CLIP-seq
MIRT880480	hsa-miR-429	CLIP-seq
MIRT880481	hsa-miR-4299	CLIP-seq
MIRT880482	hsa-miR-4300	CLIP-seq
MIRT880483	hsa-miR-4317	CLIP-seq
MIRT880484	hsa-miR-4318	CLIP-seq
MIRT880485	hsa-miR-4456	CLIP-seq
MIRT880486	hsa-miR-4481	CLIP-seq
MIRT880444	hsa-miR-4488	CLIP-seq
MIRT880445	hsa-miR-449c	CLIP-seq
MIRT880487	hsa-miR-4505	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT880488	hsa-miR-4648	CLIP-seq
MIRT880489	hsa-miR-4651	CLIP-seq
MIRT880490	hsa-miR-4654	CLIP-seq
MIRT880491	hsa-miR-4662a-5p	CLIP-seq
MIRT880492	hsa-miR-4664-5p	CLIP-seq
MIRT880447	hsa-miR-4665-5p	CLIP-seq
MIRT880493	hsa-miR-4676-5p	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT880494	hsa-miR-4693-5p	CLIP-seq
MIRT880450	hsa-miR-4697-5p	CLIP-seq
MIRT880451	hsa-miR-4703-3p	CLIP-seq
MIRT880452	hsa-miR-4715-5p	CLIP-seq
MIRT880495	hsa-miR-4726-3p	CLIP-seq
MIRT880453	hsa-miR-4736	CLIP-seq
MIRT880496	hsa-miR-4742-3p	CLIP-seq
MIRT880454	hsa-miR-4742-5p	CLIP-seq
MIRT880497	hsa-miR-4745-5p	CLIP-seq
MIRT880498	hsa-miR-4756-3p	CLIP-seq
MIRT880499	hsa-miR-4769-5p	CLIP-seq
MIRT880500	hsa-miR-4772-5p	CLIP-seq
MIRT880501	hsa-miR-4797-5p	CLIP-seq
MIRT880502	hsa-miR-488	CLIP-seq
MIRT880503	hsa-miR-541	CLIP-seq
MIRT880504	hsa-miR-548q	CLIP-seq
MIRT880505	hsa-miR-575	CLIP-seq
MIRT880506	hsa-miR-608	CLIP-seq
MIRT880507	hsa-miR-609	CLIP-seq
MIRT880508	hsa-miR-622	CLIP-seq
MIRT880509	hsa-miR-654-5p	CLIP-seq
MIRT880510	hsa-miR-761	CLIP-seq
MIRT880511	hsa-miR-892a	CLIP-seq
MIRT880512	hsa-miR-920	CLIP-seq
MIRT880513	hsa-miR-92a	CLIP-seq
MIRT880514	hsa-miR-92b	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT1960824	hsa-miR-1228	CLIP-seq
MIRT880433	hsa-miR-125a-3p	CLIP-seq
MIRT880434	hsa-miR-1275	CLIP-seq
MIRT1960825	hsa-miR-1285	CLIP-seq
MIRT1960826	hsa-miR-1293	CLIP-seq
MIRT1960827	hsa-miR-140-5p	CLIP-seq
MIRT1960828	hsa-miR-1587	CLIP-seq
MIRT880460	hsa-miR-1909	CLIP-seq
MIRT880462	hsa-miR-1972	CLIP-seq
MIRT880465	hsa-miR-214	CLIP-seq
MIRT880437	hsa-miR-24	CLIP-seq
MIRT880438	hsa-miR-2682	CLIP-seq
MIRT1960829	hsa-miR-3150a-3p	CLIP-seq
MIRT1960830	hsa-miR-3175	CLIP-seq
MIRT1960831	hsa-miR-3187-5p	CLIP-seq
MIRT1960832	hsa-miR-3199	CLIP-seq
MIRT1960833	hsa-miR-342-3p	CLIP-seq
MIRT880474	hsa-miR-342-5p	CLIP-seq
MIRT1960834	hsa-miR-3545-5p	CLIP-seq
MIRT880475	hsa-miR-3619-5p	CLIP-seq
MIRT1960835	hsa-miR-3620	CLIP-seq
MIRT880439	hsa-miR-3665	CLIP-seq
MIRT880478	hsa-miR-3682-3p	CLIP-seq
MIRT1960836	hsa-miR-378g	CLIP-seq
MIRT880479	hsa-miR-383	CLIP-seq
MIRT1960837	hsa-miR-3940-5p	CLIP-seq
MIRT880440	hsa-miR-4259	CLIP-seq
MIRT880441	hsa-miR-4269	CLIP-seq
MIRT880442	hsa-miR-4284	CLIP-seq
MIRT1960838	hsa-miR-4460	CLIP-seq
MIRT880486	hsa-miR-4481	CLIP-seq
MIRT1960839	hsa-miR-4483	CLIP-seq
MIRT880444	hsa-miR-4488	CLIP-seq
MIRT1960840	hsa-miR-4492	CLIP-seq
MIRT1960841	hsa-miR-4498	CLIP-seq
MIRT880445	hsa-miR-449c	CLIP-seq
MIRT880487	hsa-miR-4505	CLIP-seq
MIRT1960842	hsa-miR-4506	CLIP-seq
MIRT1960843	hsa-miR-4507	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT1960844	hsa-miR-4515	CLIP-seq
MIRT880489	hsa-miR-4651	CLIP-seq
MIRT1960845	hsa-miR-4652-5p	CLIP-seq
MIRT880490	hsa-miR-4654	CLIP-seq
MIRT1960846	hsa-miR-4656	CLIP-seq
MIRT880492	hsa-miR-4664-5p	CLIP-seq
MIRT880447	hsa-miR-4665-5p	CLIP-seq
MIRT1960847	hsa-miR-4667-5p	CLIP-seq
MIRT1960848	hsa-miR-4675	CLIP-seq
MIRT1960849	hsa-miR-4688	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT880450	hsa-miR-4697-5p	CLIP-seq
MIRT1960850	hsa-miR-4700-5p	CLIP-seq
MIRT880451	hsa-miR-4703-3p	CLIP-seq
MIRT880452	hsa-miR-4715-5p	CLIP-seq
MIRT1960851	hsa-miR-4731-5p	CLIP-seq
MIRT880453	hsa-miR-4736	CLIP-seq
MIRT1960852	hsa-miR-4741	CLIP-seq
MIRT880454	hsa-miR-4742-5p	CLIP-seq
MIRT880497	hsa-miR-4745-5p	CLIP-seq
MIRT880499	hsa-miR-4769-5p	CLIP-seq
MIRT880500	hsa-miR-4772-5p	CLIP-seq
MIRT1960853	hsa-miR-4774-5p	CLIP-seq
MIRT1960854	hsa-miR-485-3p	CLIP-seq
MIRT880503	hsa-miR-541	CLIP-seq
MIRT1960855	hsa-miR-563	CLIP-seq
MIRT1960856	hsa-miR-584	CLIP-seq
MIRT880506	hsa-miR-608	CLIP-seq
MIRT880507	hsa-miR-609	CLIP-seq
MIRT1960857	hsa-miR-612	CLIP-seq
MIRT880509	hsa-miR-654-5p	CLIP-seq
MIRT880510	hsa-miR-761	CLIP-seq
MIRT1960858	hsa-miR-762	CLIP-seq
MIRT1960859	hsa-miR-939	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT2197560	hsa-miR-4712-3p	CLIP-seq
MIRT2197561	hsa-miR-4728-5p	CLIP-seq
MIRT2197562	hsa-miR-4765	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT880432	hsa-miR-1252	CLIP-seq
MIRT880433	hsa-miR-125a-3p	CLIP-seq
MIRT2197563	hsa-miR-1260	CLIP-seq
MIRT2197564	hsa-miR-1260b	CLIP-seq
MIRT880436	hsa-miR-1324	CLIP-seq
MIRT880460	hsa-miR-1909	CLIP-seq
MIRT880462	hsa-miR-1972	CLIP-seq
MIRT880465	hsa-miR-214	CLIP-seq
MIRT880437	hsa-miR-24	CLIP-seq
MIRT880438	hsa-miR-2682	CLIP-seq
MIRT2197565	hsa-miR-29a	CLIP-seq
MIRT2197566	hsa-miR-29b	CLIP-seq
MIRT2197567	hsa-miR-29c	CLIP-seq
MIRT2197568	hsa-miR-3166	CLIP-seq
MIRT880474	hsa-miR-342-5p	CLIP-seq
MIRT880475	hsa-miR-3619-5p	CLIP-seq
MIRT880439	hsa-miR-3665	CLIP-seq
MIRT1960836	hsa-miR-378g	CLIP-seq
MIRT880440	hsa-miR-4259	CLIP-seq
MIRT880441	hsa-miR-4269	CLIP-seq
MIRT880442	hsa-miR-4284	CLIP-seq
MIRT880444	hsa-miR-4488	CLIP-seq
MIRT1960840	hsa-miR-4492	CLIP-seq
MIRT1960841	hsa-miR-4498	CLIP-seq
MIRT880445	hsa-miR-449c	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT2197569	hsa-miR-4530	CLIP-seq
MIRT880489	hsa-miR-4651	CLIP-seq
MIRT880492	hsa-miR-4664-5p	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT880450	hsa-miR-4697-5p	CLIP-seq
MIRT880451	hsa-miR-4703-3p	CLIP-seq
MIRT2197560	hsa-miR-4712-3p	CLIP-seq
MIRT880452	hsa-miR-4715-5p	CLIP-seq
MIRT880453	hsa-miR-4736	CLIP-seq
MIRT880454	hsa-miR-4742-5p	CLIP-seq
MIRT2197562	hsa-miR-4765	CLIP-seq
MIRT1960854	hsa-miR-485-3p	CLIP-seq
MIRT2197570	hsa-miR-532-3p	CLIP-seq
MIRT880503	hsa-miR-541	CLIP-seq
MIRT1960855	hsa-miR-563	CLIP-seq
MIRT1960856	hsa-miR-584	CLIP-seq
MIRT880506	hsa-miR-608	CLIP-seq
MIRT880507	hsa-miR-609	CLIP-seq
MIRT880509	hsa-miR-654-5p	CLIP-seq
MIRT880510	hsa-miR-761	CLIP-seq
MIRT1960858	hsa-miR-762	CLIP-seq
MIRT2197571	hsa-miR-922	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT1960836	hsa-miR-378g	CLIP-seq
MIRT1960840	hsa-miR-4492	CLIP-seq
MIRT1960841	hsa-miR-4498	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT1960858	hsa-miR-762	CLIP-seq
MIRT880455	hsa-miR-874	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT2446689	hsa-miR-1286	CLIP-seq
MIRT2446690	hsa-miR-185	CLIP-seq
MIRT880467	hsa-miR-296-5p	CLIP-seq
MIRT880468	hsa-miR-3151	CLIP-seq
MIRT2446691	hsa-miR-4306	CLIP-seq
MIRT880486	hsa-miR-4481	CLIP-seq
MIRT2446692	hsa-miR-4644	CLIP-seq
MIRT2446693	hsa-miR-4722-5p	CLIP-seq
MIRT880497	hsa-miR-4745-5p	CLIP-seq
MIRT2500923	hsa-miR-1207-5p	CLIP-seq
MIRT1960824	hsa-miR-1228	CLIP-seq
MIRT880432	hsa-miR-1252	CLIP-seq
MIRT880433	hsa-miR-125a-3p	CLIP-seq
MIRT880434	hsa-miR-1275	CLIP-seq
MIRT1960825	hsa-miR-1285	CLIP-seq
MIRT1960826	hsa-miR-1293	CLIP-seq
MIRT880436	hsa-miR-1324	CLIP-seq
MIRT2500924	hsa-miR-1343	CLIP-seq
MIRT2500925	hsa-miR-135a	CLIP-seq
MIRT2500926	hsa-miR-135b	CLIP-seq
MIRT880460	hsa-miR-1909	CLIP-seq
MIRT880462	hsa-miR-1972	CLIP-seq
MIRT880465	hsa-miR-214	CLIP-seq
MIRT2500927	hsa-miR-223	CLIP-seq
MIRT880437	hsa-miR-24	CLIP-seq
MIRT880438	hsa-miR-2682	CLIP-seq
MIRT880467	hsa-miR-296-5p	CLIP-seq
MIRT2197565	hsa-miR-29a	CLIP-seq
MIRT2197566	hsa-miR-29b	CLIP-seq
MIRT2197567	hsa-miR-29c	CLIP-seq
MIRT2500928	hsa-miR-3065-3p	CLIP-seq
MIRT2500929	hsa-miR-3160-3p	CLIP-seq
MIRT2500930	hsa-miR-3162-3p	CLIP-seq
MIRT2197568	hsa-miR-3166	CLIP-seq
MIRT1960831	hsa-miR-3187-5p	CLIP-seq
MIRT1960833	hsa-miR-342-3p	CLIP-seq
MIRT880474	hsa-miR-342-5p	CLIP-seq
MIRT2500931	hsa-miR-361-3p	CLIP-seq
MIRT880475	hsa-miR-3619-5p	CLIP-seq
MIRT1960835	hsa-miR-3620	CLIP-seq
MIRT880439	hsa-miR-3665	CLIP-seq
MIRT2500932	hsa-miR-3918	CLIP-seq
MIRT1960837	hsa-miR-3940-5p	CLIP-seq
MIRT880440	hsa-miR-4259	CLIP-seq
MIRT2500933	hsa-miR-4268	CLIP-seq
MIRT880441	hsa-miR-4269	CLIP-seq
MIRT2500934	hsa-miR-4277	CLIP-seq
MIRT880442	hsa-miR-4284	CLIP-seq
MIRT880486	hsa-miR-4481	CLIP-seq
MIRT1960839	hsa-miR-4483	CLIP-seq
MIRT2500935	hsa-miR-4487	CLIP-seq
MIRT880444	hsa-miR-4488	CLIP-seq
MIRT880445	hsa-miR-449c	CLIP-seq
MIRT1960842	hsa-miR-4506	CLIP-seq
MIRT1960843	hsa-miR-4507	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT2197569	hsa-miR-4530	CLIP-seq
MIRT880489	hsa-miR-4651	CLIP-seq
MIRT880490	hsa-miR-4654	CLIP-seq
MIRT2500936	hsa-miR-4663	CLIP-seq
MIRT880492	hsa-miR-4664-5p	CLIP-seq
MIRT880447	hsa-miR-4665-5p	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT880450	hsa-miR-4697-5p	CLIP-seq
MIRT880451	hsa-miR-4703-3p	CLIP-seq
MIRT2197560	hsa-miR-4712-3p	CLIP-seq
MIRT880452	hsa-miR-4715-5p	CLIP-seq
MIRT2500937	hsa-miR-4725-5p	CLIP-seq
MIRT880453	hsa-miR-4736	CLIP-seq
MIRT880454	hsa-miR-4742-5p	CLIP-seq
MIRT880497	hsa-miR-4745-5p	CLIP-seq
MIRT2500938	hsa-miR-4763-3p	CLIP-seq
MIRT2197562	hsa-miR-4765	CLIP-seq
MIRT880499	hsa-miR-4769-5p	CLIP-seq
MIRT2500939	hsa-miR-501-3p	CLIP-seq
MIRT2500940	hsa-miR-502-3p	CLIP-seq
MIRT2500941	hsa-miR-504	CLIP-seq
MIRT880503	hsa-miR-541	CLIP-seq
MIRT2500942	hsa-miR-558	CLIP-seq
MIRT1960855	hsa-miR-563	CLIP-seq
MIRT880506	hsa-miR-608	CLIP-seq
MIRT880507	hsa-miR-609	CLIP-seq
MIRT1960857	hsa-miR-612	CLIP-seq
MIRT880509	hsa-miR-654-5p	CLIP-seq
MIRT2500943	hsa-miR-720	CLIP-seq
MIRT880510	hsa-miR-761	CLIP-seq
MIRT880455	hsa-miR-874	CLIP-seq
MIRT2197571	hsa-miR-922	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq
MIRT2500923	hsa-miR-1207-5p	CLIP-seq
MIRT1960824	hsa-miR-1228	CLIP-seq
MIRT880432	hsa-miR-1252	CLIP-seq
MIRT880433	hsa-miR-125a-3p	CLIP-seq
MIRT880434	hsa-miR-1275	CLIP-seq
MIRT1960825	hsa-miR-1285	CLIP-seq
MIRT1960826	hsa-miR-1293	CLIP-seq
MIRT880435	hsa-miR-1294	CLIP-seq
MIRT880436	hsa-miR-1324	CLIP-seq
MIRT2500924	hsa-miR-1343	CLIP-seq
MIRT2500925	hsa-miR-135a	CLIP-seq
MIRT2500926	hsa-miR-135b	CLIP-seq
MIRT880460	hsa-miR-1909	CLIP-seq
MIRT880462	hsa-miR-1972	CLIP-seq
MIRT880465	hsa-miR-214	CLIP-seq
MIRT2500927	hsa-miR-223	CLIP-seq
MIRT880437	hsa-miR-24	CLIP-seq
MIRT880438	hsa-miR-2682	CLIP-seq
MIRT880467	hsa-miR-296-5p	CLIP-seq
MIRT2197565	hsa-miR-29a	CLIP-seq
MIRT2197566	hsa-miR-29b	CLIP-seq
MIRT2197567	hsa-miR-29c	CLIP-seq
MIRT2500928	hsa-miR-3065-3p	CLIP-seq
MIRT2500929	hsa-miR-3160-3p	CLIP-seq
MIRT2500930	hsa-miR-3162-3p	CLIP-seq
MIRT2197568	hsa-miR-3166	CLIP-seq
MIRT2677895	hsa-miR-3184	CLIP-seq
MIRT1960831	hsa-miR-3187-5p	CLIP-seq
MIRT756131	hsa-miR-324-5p	CLIP-seq
MIRT1960833	hsa-miR-342-3p	CLIP-seq
MIRT880474	hsa-miR-342-5p	CLIP-seq
MIRT2500931	hsa-miR-361-3p	CLIP-seq
MIRT880475	hsa-miR-3619-5p	CLIP-seq
MIRT1960835	hsa-miR-3620	CLIP-seq
MIRT880439	hsa-miR-3665	CLIP-seq
MIRT2677896	hsa-miR-3688-5p	CLIP-seq
MIRT2500932	hsa-miR-3918	CLIP-seq
MIRT2677897	hsa-miR-423-5p	CLIP-seq
MIRT880440	hsa-miR-4259	CLIP-seq
MIRT2500933	hsa-miR-4268	CLIP-seq
MIRT880441	hsa-miR-4269	CLIP-seq
MIRT2500934	hsa-miR-4277	CLIP-seq
MIRT880442	hsa-miR-4284	CLIP-seq
MIRT880443	hsa-miR-4316	CLIP-seq
MIRT2677898	hsa-miR-4455	CLIP-seq
MIRT880486	hsa-miR-4481	CLIP-seq
MIRT1960839	hsa-miR-4483	CLIP-seq
MIRT2500935	hsa-miR-4487	CLIP-seq
MIRT880444	hsa-miR-4488	CLIP-seq
MIRT880445	hsa-miR-449c	CLIP-seq
MIRT1960842	hsa-miR-4506	CLIP-seq
MIRT880446	hsa-miR-4514	CLIP-seq
MIRT2197569	hsa-miR-4530	CLIP-seq
MIRT2677899	hsa-miR-4642	CLIP-seq
MIRT880489	hsa-miR-4651	CLIP-seq
MIRT880490	hsa-miR-4654	CLIP-seq
MIRT2500936	hsa-miR-4663	CLIP-seq
MIRT880492	hsa-miR-4664-5p	CLIP-seq
MIRT880447	hsa-miR-4665-5p	CLIP-seq
MIRT880448	hsa-miR-4677-3p	CLIP-seq
MIRT880449	hsa-miR-4692	CLIP-seq
MIRT880450	hsa-miR-4697-5p	CLIP-seq
MIRT880451	hsa-miR-4703-3p	CLIP-seq
MIRT2197560	hsa-miR-4712-3p	CLIP-seq
MIRT880452	hsa-miR-4715-5p	CLIP-seq
MIRT2500937	hsa-miR-4725-5p	CLIP-seq
MIRT880453	hsa-miR-4736	CLIP-seq
MIRT880454	hsa-miR-4742-5p	CLIP-seq
MIRT880497	hsa-miR-4745-5p	CLIP-seq
MIRT2500938	hsa-miR-4763-3p	CLIP-seq
MIRT2197562	hsa-miR-4765	CLIP-seq
MIRT880499	hsa-miR-4769-5p	CLIP-seq
MIRT2500939	hsa-miR-501-3p	CLIP-seq
MIRT2500940	hsa-miR-502-3p	CLIP-seq
MIRT2500941	hsa-miR-504	CLIP-seq
MIRT880503	hsa-miR-541	CLIP-seq
MIRT2500942	hsa-miR-558	CLIP-seq
MIRT880506	hsa-miR-608	CLIP-seq
MIRT880507	hsa-miR-609	CLIP-seq
MIRT1960857	hsa-miR-612	CLIP-seq
MIRT2677900	hsa-miR-644	CLIP-seq
MIRT880509	hsa-miR-654-5p	CLIP-seq
MIRT2500943	hsa-miR-720	CLIP-seq
MIRT880510	hsa-miR-761	CLIP-seq
MIRT880455	hsa-miR-874	CLIP-seq
MIRT2197571	hsa-miR-922	CLIP-seq
MIRT880456	hsa-miR-940	CLIP-seq

Show/Hide all (46)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000307	Component	Cyclin-dependent protein kinase holoenzyme complex	IPI	19524571
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	22184064, 22796189
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004693	Function	Cyclin-dependent protein serine/threonine kinase activity	IBA
GO:0004693	Function	Cyclin-dependent protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	12154078, 16091426, 22184064, 25416956, 25852190, 26496610, 28514442, 32296183, 32707033, 33961781, 35271311, 36931259
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	22798068
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA	19524571
GO:0005886	Component	Plasma membrane	IEA
GO:0006468	Process	Protein phosphorylation	TAS	1437147
GO:0006887	Process	Exocytosis	IBA
GO:0006887	Process	Exocytosis	IEA
GO:0006887	Process	Exocytosis	ISS
GO:0007283	Process	Spermatogenesis	IEA
GO:0007283	Process	Spermatogenesis	ISS
GO:0007283	Process	Spermatogenesis	NAS	19524571
GO:0008021	Component	Synaptic vesicle	IBA
GO:0008021	Component	Synaptic vesicle	IEA
GO:0008021	Component	Synaptic vesicle	ISS
GO:0009898	Component	Cytoplasmic side of plasma membrane	IDA	22184064
GO:0010508	Process	Positive regulation of autophagy	IDA	32098961
GO:0015630	Component	Microtubule cytoskeleton	IDA
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030133	Component	Transport vesicle	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0030252	Process	Growth hormone secretion	IEA
GO:0030252	Process	Growth hormone secretion	ISS
GO:0031175	Process	Neuron projection development	IBA
GO:0031175	Process	Neuron projection development	IEA
GO:0031175	Process	Neuron projection development	ISS
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0045202	Component	Synapse	IEA
GO:0061178	Process	Regulation of insulin secretion involved in cellular response to glucose stimulus	IEA
GO:0061178	Process	Regulation of insulin secretion involved in cellular response to glucose stimulus	IMP	22798068
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1901987	Process	Regulation of cell cycle phase transition	IBA

MIM	HGNC	e!Ensembl
311550	8749	ENSG00000102225

Q00536

Protein name

Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)

Protein function

Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron

PDB

3MTL , 5G6V

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	165 → 446	Protein kinase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in pancreas islets (at protein level). Detected in brain and pancreas. {ECO:0000269|PubMed:22798068}.

Sequence

MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
MPDSGRPAFRVVDTEF

Sequence length

496

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (16)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CDK16-related disorder	Benign; Uncertain significance; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CDK16-related Intellectual Disability	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial pancreatic carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DISABILITY	—	Disgenet, Orphanet Disgenet, Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TERATOZOOSPERMIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED COMPLEX NEURODEVELOPMENTAL DISORDER	—	ClinGen, GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (45)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adult Medulloblastoma	Medulloblastoma	BEFREE	25402633		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	36323681	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	21315692		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	22417847		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	25920913		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	25790448	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	25790448	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	22417847		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	29344296		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	26546806	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood Medulloblastoma	Medulloblastoma	BEFREE	25402633		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	37373155	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cutaneous Melanoma	Melanoma	BEFREE	30396963		★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	30248539		★★★★★ ★☆☆☆☆ Found in Text Mining only
Disorder of eye	Disorder Of Eye	BEFREE	9801870		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	28498444		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	GENOMICS_ENGLAND_DG	25644381		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Intellectual Disability	Intellectual developmental disorder	Pubtator	36323681	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Kidney Neoplasms	Kidney neoplasm	Pubtator	30411496	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	28498444, 28716136		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	29344296, 34687270	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	25920913		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	29344296		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	29366808		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	28274513		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	28498444		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	22417847		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	25205104, 25920913, 28057719, 28274513, 28352193, 28498444, 29112787, 29674275, 30031856, 30992425		★★★★★ ★☆☆☆☆ Found in Text Mining only
Medulloblastoma	Medulloblastoma	BEFREE	25402633		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	28352193, 29100459, 29112787, 30396963		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Melanoma	Pubtator	29112787	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Microcephaly	Microcephaly	BEFREE	23692340		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	25205104, 25402633, 28274513		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	29674275, 29731854, 31715289		★★★★★ ★☆☆☆☆ Found in Text Mining only
Noninfiltrating Intraductal Carcinoma	Ductal carcinoma	BEFREE	12473591		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	29366808		★★★★★ ★☆☆☆☆ Found in Text Mining only
Papillary thyroid carcinoma	Papillary thyroid carcinoma	BEFREE	29387247		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pleomorphic Xanthoastrocytoma	Pleomorphic Xanthoastrocytoma	BEFREE	24894018		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	BEFREE	25205104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	25790448	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Insufficiency	Renal Insufficiency	BEFREE	31086184		★★★★★ ★☆☆☆☆ Found in Text Mining only
Retinal Diseases	Retinal Diseases	BEFREE	9801870		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	PSYGENET_DG	16978587, 20687111		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Septicemia	Septicemia	BEFREE	18166586		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of skin	Skin carcinoma	BEFREE	28274513		★★★★★ ★☆☆☆☆ Found in Text Mining only

CDK16 (cyclin dependent kinase 16)