FAM178B (family with sequence similarity 178 member B)

Gene

• Entrez ID: 51252
• Gene name: Family with sequence similarity 178 member B
• Gene symbol: FAM178B
• Synonyms (NCBI Gene): -
• Chromosome: 2
• Chromosome location: 2q11.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT982316	hsa-miR-125a-5p	CLIP-seq
MIRT982317	hsa-miR-125b	CLIP-seq
MIRT982318	hsa-miR-145	CLIP-seq
MIRT982319	hsa-miR-1827	CLIP-seq
MIRT982320	hsa-miR-2467-3p	CLIP-seq
MIRT982321	hsa-miR-3074-5p	CLIP-seq
MIRT982322	hsa-miR-3155	CLIP-seq
MIRT982323	hsa-miR-3155b	CLIP-seq
MIRT982324	hsa-miR-370	CLIP-seq
MIRT982325	hsa-miR-3925-3p	CLIP-seq
MIRT982326	hsa-miR-4319	CLIP-seq
MIRT982327	hsa-miR-4691-5p	CLIP-seq
MIRT982328	hsa-miR-4732-3p	CLIP-seq
MIRT982329	hsa-miR-4786-3p	CLIP-seq
MIRT982330	hsa-miR-484	CLIP-seq
MIRT982331	hsa-miR-516a-3p	CLIP-seq
MIRT982332	hsa-miR-665	CLIP-seq
MIRT982333	hsa-miR-670	CLIP-seq
MIRT982334	hsa-miR-940	CLIP-seq
MIRT1991257	hsa-miR-1207-5p	CLIP-seq
MIRT982319	hsa-miR-1827	CLIP-seq
MIRT1991258	hsa-miR-1909	CLIP-seq
MIRT982320	hsa-miR-2467-3p	CLIP-seq
MIRT982321	hsa-miR-3074-5p	CLIP-seq
MIRT982322	hsa-miR-3155	CLIP-seq
MIRT982323	hsa-miR-3155b	CLIP-seq
MIRT1991259	hsa-miR-3180	CLIP-seq
MIRT1991260	hsa-miR-3180-3p	CLIP-seq
MIRT1991261	hsa-miR-3196	CLIP-seq
MIRT982324	hsa-miR-370	CLIP-seq
MIRT1991262	hsa-miR-4508	CLIP-seq
MIRT1991263	hsa-miR-4688	CLIP-seq
MIRT1991264	hsa-miR-4736	CLIP-seq
MIRT1991265	hsa-miR-4763-3p	CLIP-seq
MIRT982329	hsa-miR-4786-3p	CLIP-seq
MIRT982330	hsa-miR-484	CLIP-seq
MIRT1991266	hsa-miR-486-3p	CLIP-seq
MIRT982332	hsa-miR-665	CLIP-seq
MIRT982334	hsa-miR-940	CLIP-seq
MIRT1991257	hsa-miR-1207-5p	CLIP-seq
MIRT1991258	hsa-miR-1909	CLIP-seq
MIRT982320	hsa-miR-2467-3p	CLIP-seq
MIRT982321	hsa-miR-3074-5p	CLIP-seq
MIRT1991259	hsa-miR-3180	CLIP-seq
MIRT1991260	hsa-miR-3180-3p	CLIP-seq
MIRT1991261	hsa-miR-3196	CLIP-seq
MIRT982324	hsa-miR-370	CLIP-seq
MIRT1991262	hsa-miR-4508	CLIP-seq
MIRT1991263	hsa-miR-4688	CLIP-seq
MIRT1991264	hsa-miR-4736	CLIP-seq
MIRT1991265	hsa-miR-4763-3p	CLIP-seq
MIRT982329	hsa-miR-4786-3p	CLIP-seq
MIRT982332	hsa-miR-665	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IXR5
• Protein name: Protein FAM178B
• Family and domains:

  Pfam

  
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  Accession	ID	Position in sequence	Description	Type
  PF14816	FAM178	337 → 689	Family of unknown function, FAM178	Family

• Sequence:

  MWPRLPGAGLAPQLRRQDQRLHFTGQMSHGLQMAGPQETVLALPLREGVQAAATVPILLY
  NLEDGLSDHPLDQGPRCPARRPCSPASAPAPTSPKKPKIQAPGETFPTDWSPPPVEFLNP
  RVLQASREAPAQRWVGVVGPQGLRRLAGELPEELEQEHLDLDPKRGLALPEKLFWNTSGL
  SQQAAAPEFSWGGSGSYFNNLDYLLQEKREQALEQERERLLLQECLNLNSLDLDEEEVPL
  TPEHRMLVEKYSVSLQTIPPVHPGETVFLPRCHPLPCILDSSLLKPRSHLEGLFLSSPPA
  QQLSFLRSGLLNILYLHMPDCPVSLLQWLFQLLTWPPETSLGAFGLLWDLIVDGIFLQPD
  EDKHLWCPSLQEVREAFHSLGAHSPALYPLGPFWHGGRVLPGEAGLNENEEQDAPQEIAL
  DISLGHIYKFLALCAQAQPGAYTDENLMGLIELLCRTSLDVGLRLLPKVDLQQLLLLLLE
  NIREWPGKLQELCCTLSWVSDHHHNLLALVQFFPDMTSRSRRLRSQLSLVVIARMLGQQE
  MLPLWQEKTQLSSLSRLLGLMRPSSLRQYLDSVPLPPCQEQQPKASAELDHKACYLCHSL
  LMLAGVVVSCQDITPDQWGELQLLCMQLDRHISTQIRESPQAMHRTMLKDLATQTYIRWQ
  ELLTHCQPQAQYFSPWKDI

• Sequence length: 679

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BIPOLAR DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Bipolar Disorder	Bipolar Disorder	GWASCAT_DG	29121268		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Glioblastoma	Glioblastoma	Pubtator	33504897	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	33504897	Associate	★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	GWASCAT_DG	29121268		★★☆☆☆ Found in Text Mining + Unknown/Other Associations