GLTP (glycolipid transfer protein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51228 |
| Gene name | Glycolipid transfer protein |
| Gene symbol | GLTP |
| Synonyms (NCBI Gene) |
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| Chromosome | 12 |
| Chromosome location | 12q24.11 |
| Summary | The protein encoded by this gene is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein. [provided by RefSeq, Jul 2008] |
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miRNA
miRNA information provided by mirtarbase database.
564
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NZD2 | ||||||||||
| Protein name | Glycolipid transfer protein (GLTP) | ||||||||||
| Protein function | Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of gluc | ||||||||||
| PDB | 1SWX , 1SX6 , 2EUK , 2EUM , 2EVD , 2EVL , 2EVS , 2EVT , 3RIC , 3RWV , 3RZN , 3S0I , 3S0K , 4GH0 , 4GHP , 4GHS , 4GIX , 4GJQ , 4GVT , 4GXD , 4GXG , 4H2Z | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected in fibroblasts (at protein level). Detected in fibroblasts and in various cancer cell lines. {ECO:0000269|PubMed:17980653, ECO:0000269|PubMed:18261224}. | ||||||||||
| Sequence |
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| Sequence length | 209 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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