Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	51141
Gene name	Insulin induced gene 2
Gene symbol	INSIG2
Synonyms (NCBI Gene)	INSIG-2
Chromosome	2
Chromosome location	2q14.1-q14.2
Summary	The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by b

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017795	hsa-miR-335-5p	Microarray	18185580
MIRT019869	hsa-miR-375	Microarray	20215506
MIRT002529	hsa-miR-373-3p	Microarray	15685193
MIRT021575	hsa-miR-142-3p	Microarray	17612493
MIRT711896	hsa-miR-7851-3p	HITS-CLIP	19536157
MIRT711895	hsa-miR-2115-3p	HITS-CLIP	19536157
MIRT711894	hsa-miR-3622a-3p	HITS-CLIP	19536157
MIRT711893	hsa-miR-3622b-3p	HITS-CLIP	19536157
MIRT711892	hsa-miR-6765-3p	HITS-CLIP	19536157
MIRT711891	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT711890	hsa-miR-4667-5p	HITS-CLIP	19536157
MIRT711889	hsa-miR-4700-5p	HITS-CLIP	19536157
MIRT711888	hsa-miR-8089	HITS-CLIP	19536157
MIRT711887	hsa-miR-4471	HITS-CLIP	19536157
MIRT711886	hsa-miR-8059	HITS-CLIP	19536157
MIRT711885	hsa-miR-4271	HITS-CLIP	19536157
MIRT711884	hsa-miR-4725-3p	HITS-CLIP	19536157
MIRT711883	hsa-miR-6780b-5p	HITS-CLIP	19536157
MIRT711882	hsa-miR-2110	HITS-CLIP	19536157
MIRT475184	hsa-miR-455-3p	HITS-CLIP	21572407
MIRT297519	hsa-miR-4517	HITS-CLIP	21572407
MIRT297521	hsa-miR-5583-3p	HITS-CLIP	21572407
MIRT297520	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT522990	hsa-miR-7151-5p	HITS-CLIP	21572407
MIRT475183	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT475182	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT297523	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT297516	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT475181	hsa-miR-6516-5p	HITS-CLIP	21572407
MIRT475180	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT475179	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT475184	hsa-miR-455-3p	PAR-CLIP	21572407
MIRT297519	hsa-miR-4517	PAR-CLIP	21572407
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	21572407
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT522990	hsa-miR-7151-5p	PAR-CLIP	21572407
MIRT475183	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT475182	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT475181	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT475179	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT475184	hsa-miR-455-3p	PAR-CLIP	21572407
MIRT297519	hsa-miR-4517	PAR-CLIP	21572407
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	21572407
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT475183	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT475182	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT475181	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT475179	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT536629	hsa-miR-335-3p	PAR-CLIP	22012620
MIRT475184	hsa-miR-455-3p	PAR-CLIP	23446348
MIRT297519	hsa-miR-4517	PAR-CLIP	23446348
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT522990	hsa-miR-7151-5p	PAR-CLIP	23446348
MIRT475183	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT475182	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT475181	hsa-miR-6516-5p	PAR-CLIP	23446348
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT475179	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT297519	hsa-miR-4517	PAR-CLIP	23446348
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT475183	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT475182	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT475179	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT475184	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT297519	hsa-miR-4517	PAR-CLIP	23592263
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	23592263
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	23592263
MIRT475183	hsa-miR-511-3p	PAR-CLIP	23592263
MIRT475182	hsa-miR-223-5p	PAR-CLIP	23592263
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	23592263
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	23592263
MIRT475181	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	23592263
MIRT475179	hsa-miR-574-5p	PAR-CLIP	23592263
MIRT711896	hsa-miR-7851-3p	HITS-CLIP	19536157
MIRT711895	hsa-miR-2115-3p	HITS-CLIP	19536157
MIRT711894	hsa-miR-3622a-3p	HITS-CLIP	19536157
MIRT711893	hsa-miR-3622b-3p	HITS-CLIP	19536157
MIRT711892	hsa-miR-6765-3p	HITS-CLIP	19536157
MIRT711891	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT711890	hsa-miR-4667-5p	HITS-CLIP	19536157
MIRT711889	hsa-miR-4700-5p	HITS-CLIP	19536157
MIRT711888	hsa-miR-8089	HITS-CLIP	19536157
MIRT711887	hsa-miR-4471	HITS-CLIP	19536157
MIRT711886	hsa-miR-8059	HITS-CLIP	19536157
MIRT711885	hsa-miR-4271	HITS-CLIP	19536157
MIRT711884	hsa-miR-4725-3p	HITS-CLIP	19536157
MIRT711883	hsa-miR-6780b-5p	HITS-CLIP	19536157
MIRT711882	hsa-miR-2110	HITS-CLIP	19536157
MIRT475184	hsa-miR-455-3p	HITS-CLIP	21572407
MIRT297519	hsa-miR-4517	HITS-CLIP	21572407
MIRT297521	hsa-miR-5583-3p	HITS-CLIP	21572407
MIRT297520	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT522990	hsa-miR-7151-5p	HITS-CLIP	21572407
MIRT475183	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT475182	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT297523	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT297516	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT475181	hsa-miR-6516-5p	HITS-CLIP	21572407
MIRT475180	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT475179	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT475184	hsa-miR-455-3p	PAR-CLIP	21572407
MIRT297519	hsa-miR-4517	PAR-CLIP	21572407
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	21572407
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT522990	hsa-miR-7151-5p	PAR-CLIP	21572407
MIRT475183	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT475182	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT475181	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT475179	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT475184	hsa-miR-455-3p	PAR-CLIP	21572407
MIRT297519	hsa-miR-4517	PAR-CLIP	21572407
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	21572407
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT475183	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT475182	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT475181	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT475179	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT536629	hsa-miR-335-3p	PAR-CLIP	22012620
MIRT475184	hsa-miR-455-3p	PAR-CLIP	23446348
MIRT297519	hsa-miR-4517	PAR-CLIP	23446348
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT522990	hsa-miR-7151-5p	PAR-CLIP	23446348
MIRT475183	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT475182	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT475181	hsa-miR-6516-5p	PAR-CLIP	23446348
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT475179	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT297519	hsa-miR-4517	PAR-CLIP	23446348
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT475183	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT475182	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT475179	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT475184	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT297519	hsa-miR-4517	PAR-CLIP	23592263
MIRT297521	hsa-miR-5583-3p	PAR-CLIP	23592263
MIRT297520	hsa-miR-5011-5p	PAR-CLIP	23592263
MIRT475183	hsa-miR-511-3p	PAR-CLIP	23592263
MIRT475182	hsa-miR-223-5p	PAR-CLIP	23592263
MIRT297523	hsa-miR-6867-5p	PAR-CLIP	23592263
MIRT297516	hsa-miR-190a-3p	PAR-CLIP	23592263
MIRT475181	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT475180	hsa-miR-1277-5p	PAR-CLIP	23592263
MIRT475179	hsa-miR-574-5p	PAR-CLIP	23592263
MIRT1067678	hsa-miR-10a	CLIP-seq
MIRT1067679	hsa-miR-10b	CLIP-seq
MIRT1067680	hsa-miR-1245b-3p	CLIP-seq
MIRT1067681	hsa-miR-1276	CLIP-seq
MIRT1067682	hsa-miR-1323	CLIP-seq
MIRT1067683	hsa-miR-139-5p	CLIP-seq
MIRT1067684	hsa-miR-2277-3p	CLIP-seq
MIRT1067685	hsa-miR-23a	CLIP-seq
MIRT1067686	hsa-miR-23b	CLIP-seq
MIRT1067687	hsa-miR-23c	CLIP-seq
MIRT1067688	hsa-miR-25	CLIP-seq
MIRT1067689	hsa-miR-3136-5p	CLIP-seq
MIRT1067690	hsa-miR-3140-3p	CLIP-seq
MIRT1067691	hsa-miR-3145-5p	CLIP-seq
MIRT1067692	hsa-miR-32	CLIP-seq
MIRT1067693	hsa-miR-320a	CLIP-seq
MIRT1067694	hsa-miR-320b	CLIP-seq
MIRT1067695	hsa-miR-320c	CLIP-seq
MIRT1067696	hsa-miR-320d	CLIP-seq
MIRT1067697	hsa-miR-3620	CLIP-seq
MIRT1067698	hsa-miR-363	CLIP-seq
MIRT1067699	hsa-miR-367	CLIP-seq
MIRT1067700	hsa-miR-3678-3p	CLIP-seq
MIRT1067701	hsa-miR-3686	CLIP-seq
MIRT1067702	hsa-miR-374c	CLIP-seq
MIRT1067703	hsa-miR-3908	CLIP-seq
MIRT1067704	hsa-miR-4311	CLIP-seq
MIRT1067705	hsa-miR-4422	CLIP-seq
MIRT1067706	hsa-miR-4429	CLIP-seq
MIRT1067707	hsa-miR-4439	CLIP-seq
MIRT1067708	hsa-miR-4513	CLIP-seq
MIRT1067709	hsa-miR-4652-3p	CLIP-seq
MIRT1067710	hsa-miR-4701-5p	CLIP-seq
MIRT1067711	hsa-miR-4709-5p	CLIP-seq
MIRT1067712	hsa-miR-4724-5p	CLIP-seq
MIRT1067713	hsa-miR-4735-5p	CLIP-seq
MIRT1067714	hsa-miR-4742-3p	CLIP-seq
MIRT1067715	hsa-miR-4744	CLIP-seq
MIRT1067716	hsa-miR-4778-5p	CLIP-seq
MIRT1067717	hsa-miR-4789-3p	CLIP-seq
MIRT1067718	hsa-miR-501-5p	CLIP-seq
MIRT1067719	hsa-miR-5096	CLIP-seq
MIRT1067720	hsa-miR-548o	CLIP-seq
MIRT1067721	hsa-miR-548v	CLIP-seq
MIRT1067722	hsa-miR-576-5p	CLIP-seq
MIRT1067723	hsa-miR-583	CLIP-seq
MIRT1067724	hsa-miR-588	CLIP-seq
MIRT1067725	hsa-miR-605	CLIP-seq
MIRT1067726	hsa-miR-655	CLIP-seq
MIRT1067727	hsa-miR-92a	CLIP-seq
MIRT1067728	hsa-miR-92b	CLIP-seq
MIRT1920506	hsa-miR-30a	CLIP-seq
MIRT1920507	hsa-miR-30b	CLIP-seq
MIRT1920508	hsa-miR-30c	CLIP-seq
MIRT1920509	hsa-miR-30d	CLIP-seq
MIRT1920510	hsa-miR-30e	CLIP-seq
MIRT1920511	hsa-miR-3684	CLIP-seq
MIRT1920512	hsa-miR-376a	CLIP-seq
MIRT1920513	hsa-miR-376b	CLIP-seq
MIRT1920514	hsa-miR-548a-5p	CLIP-seq
MIRT1920515	hsa-miR-548ab	CLIP-seq
MIRT1920516	hsa-miR-548ak	CLIP-seq
MIRT1920517	hsa-miR-548b-5p	CLIP-seq
MIRT1920518	hsa-miR-548c-5p	CLIP-seq
MIRT1920519	hsa-miR-548d-5p	CLIP-seq
MIRT1920520	hsa-miR-548h	CLIP-seq
MIRT1920521	hsa-miR-548i	CLIP-seq
MIRT1920522	hsa-miR-548j	CLIP-seq
MIRT1920523	hsa-miR-548w	CLIP-seq
MIRT1920524	hsa-miR-548y	CLIP-seq
MIRT1920525	hsa-miR-559	CLIP-seq
MIRT1920506	hsa-miR-30a	CLIP-seq
MIRT1920507	hsa-miR-30b	CLIP-seq
MIRT1920508	hsa-miR-30c	CLIP-seq
MIRT1920509	hsa-miR-30d	CLIP-seq
MIRT1920510	hsa-miR-30e	CLIP-seq
MIRT1920511	hsa-miR-3684	CLIP-seq
MIRT1920512	hsa-miR-376a	CLIP-seq
MIRT1920513	hsa-miR-376b	CLIP-seq
MIRT1920514	hsa-miR-548a-5p	CLIP-seq
MIRT1920515	hsa-miR-548ab	CLIP-seq
MIRT1920516	hsa-miR-548ak	CLIP-seq
MIRT1920517	hsa-miR-548b-5p	CLIP-seq
MIRT1920518	hsa-miR-548c-5p	CLIP-seq
MIRT1920519	hsa-miR-548d-5p	CLIP-seq
MIRT1920520	hsa-miR-548h	CLIP-seq
MIRT1920521	hsa-miR-548i	CLIP-seq
MIRT1920522	hsa-miR-548j	CLIP-seq
MIRT1920523	hsa-miR-548w	CLIP-seq
MIRT1920524	hsa-miR-548y	CLIP-seq
MIRT1920525	hsa-miR-559	CLIP-seq
MIRT2016432	hsa-miR-138	CLIP-seq
MIRT1067690	hsa-miR-3140-3p	CLIP-seq
MIRT2016433	hsa-miR-3156-5p	CLIP-seq
MIRT2016434	hsa-miR-4695-3p	CLIP-seq
MIRT1067710	hsa-miR-4701-5p	CLIP-seq
MIRT2016435	hsa-miR-582-5p	CLIP-seq
MIRT1067724	hsa-miR-588	CLIP-seq
MIRT2016436	hsa-miR-590-3p	CLIP-seq
MIRT2016437	hsa-miR-622	CLIP-seq
MIRT2248665	hsa-miR-124	CLIP-seq
MIRT1067681	hsa-miR-1276	CLIP-seq
MIRT2248666	hsa-miR-140-5p	CLIP-seq
MIRT1067685	hsa-miR-23a	CLIP-seq
MIRT1067686	hsa-miR-23b	CLIP-seq
MIRT1067687	hsa-miR-23c	CLIP-seq
MIRT2248667	hsa-miR-27a	CLIP-seq
MIRT2248668	hsa-miR-27b	CLIP-seq
MIRT1067689	hsa-miR-3136-5p	CLIP-seq
MIRT2248669	hsa-miR-3143	CLIP-seq
MIRT1067691	hsa-miR-3145-5p	CLIP-seq
MIRT2016433	hsa-miR-3156-5p	CLIP-seq
MIRT2248670	hsa-miR-338-5p	CLIP-seq
MIRT2248671	hsa-miR-3664-5p	CLIP-seq
MIRT2248672	hsa-miR-3680	CLIP-seq
MIRT2248673	hsa-miR-3977	CLIP-seq
MIRT2248674	hsa-miR-4267	CLIP-seq
MIRT2248675	hsa-miR-4289	CLIP-seq
MIRT1067704	hsa-miR-4311	CLIP-seq
MIRT1067707	hsa-miR-4439	CLIP-seq
MIRT1067708	hsa-miR-4513	CLIP-seq
MIRT1067710	hsa-miR-4701-5p	CLIP-seq
MIRT1067711	hsa-miR-4709-5p	CLIP-seq
MIRT2248676	hsa-miR-4714-5p	CLIP-seq
MIRT1067712	hsa-miR-4724-5p	CLIP-seq
MIRT1067715	hsa-miR-4744	CLIP-seq
MIRT2248677	hsa-miR-4768-5p	CLIP-seq
MIRT2248678	hsa-miR-483-3p	CLIP-seq
MIRT1067718	hsa-miR-501-5p	CLIP-seq
MIRT2248679	hsa-miR-506	CLIP-seq
MIRT2248680	hsa-miR-513a-5p	CLIP-seq
MIRT2248681	hsa-miR-548an	CLIP-seq
MIRT1067723	hsa-miR-583	CLIP-seq
MIRT1067724	hsa-miR-588	CLIP-seq
MIRT2016437	hsa-miR-622	CLIP-seq
MIRT2248682	hsa-miR-634	CLIP-seq
MIRT2248683	hsa-miR-642b	CLIP-seq
MIRT2248684	hsa-miR-873	CLIP-seq
MIRT1067678	hsa-miR-10a	CLIP-seq
MIRT1067679	hsa-miR-10b	CLIP-seq
MIRT2552208	hsa-miR-1208	CLIP-seq
MIRT2552209	hsa-miR-1228	CLIP-seq
MIRT2552210	hsa-miR-1238	CLIP-seq
MIRT2248665	hsa-miR-124	CLIP-seq
MIRT1067680	hsa-miR-1245b-3p	CLIP-seq
MIRT2552211	hsa-miR-1264	CLIP-seq
MIRT1067681	hsa-miR-1276	CLIP-seq
MIRT2552212	hsa-miR-1283	CLIP-seq
MIRT2552213	hsa-miR-1296	CLIP-seq
MIRT2552214	hsa-miR-1324	CLIP-seq
MIRT2016432	hsa-miR-138	CLIP-seq
MIRT1067683	hsa-miR-139-5p	CLIP-seq
MIRT2248666	hsa-miR-140-5p	CLIP-seq
MIRT2552215	hsa-miR-155	CLIP-seq
MIRT2552216	hsa-miR-183	CLIP-seq
MIRT2552217	hsa-miR-19a	CLIP-seq
MIRT2552218	hsa-miR-19b	CLIP-seq
MIRT2552219	hsa-miR-2276	CLIP-seq
MIRT2552220	hsa-miR-2467-3p	CLIP-seq
MIRT1067688	hsa-miR-25	CLIP-seq
MIRT2248667	hsa-miR-27a	CLIP-seq
MIRT2248668	hsa-miR-27b	CLIP-seq
MIRT2552221	hsa-miR-2909	CLIP-seq
MIRT2552222	hsa-miR-3117-5p	CLIP-seq
MIRT2552223	hsa-miR-3119	CLIP-seq
MIRT2552224	hsa-miR-3123	CLIP-seq
MIRT2552225	hsa-miR-3124-3p	CLIP-seq
MIRT2552226	hsa-miR-3129-3p	CLIP-seq
MIRT1067690	hsa-miR-3140-3p	CLIP-seq
MIRT2248669	hsa-miR-3143	CLIP-seq
MIRT1067691	hsa-miR-3145-5p	CLIP-seq
MIRT2552227	hsa-miR-3148	CLIP-seq
MIRT2552228	hsa-miR-3150a-5p	CLIP-seq
MIRT2552229	hsa-miR-3150b-5p	CLIP-seq
MIRT2016433	hsa-miR-3156-5p	CLIP-seq
MIRT2552230	hsa-miR-3157-3p	CLIP-seq
MIRT2552231	hsa-miR-3182	CLIP-seq
MIRT2552232	hsa-miR-3198	CLIP-seq
MIRT1067692	hsa-miR-32	CLIP-seq
MIRT1067693	hsa-miR-320a	CLIP-seq
MIRT1067694	hsa-miR-320b	CLIP-seq
MIRT1067695	hsa-miR-320c	CLIP-seq
MIRT1067696	hsa-miR-320d	CLIP-seq
MIRT2552233	hsa-miR-337-3p	CLIP-seq
MIRT2552234	hsa-miR-342-3p	CLIP-seq
MIRT2552235	hsa-miR-3545-3p	CLIP-seq
MIRT2552236	hsa-miR-3613-3p	CLIP-seq
MIRT2552237	hsa-miR-3618	CLIP-seq
MIRT1067697	hsa-miR-3620	CLIP-seq
MIRT2552238	hsa-miR-3622b-5p	CLIP-seq
MIRT1067698	hsa-miR-363	CLIP-seq
MIRT1067699	hsa-miR-367	CLIP-seq
MIRT1067700	hsa-miR-3678-3p	CLIP-seq
MIRT2248672	hsa-miR-3680	CLIP-seq
MIRT2552239	hsa-miR-3685	CLIP-seq
MIRT1067701	hsa-miR-3686	CLIP-seq
MIRT2552240	hsa-miR-3688-3p	CLIP-seq
MIRT2552241	hsa-miR-3691-5p	CLIP-seq
MIRT2552242	hsa-miR-383	CLIP-seq
MIRT2552243	hsa-miR-384	CLIP-seq
MIRT1067703	hsa-miR-3908	CLIP-seq
MIRT2552244	hsa-miR-3919	CLIP-seq
MIRT2248673	hsa-miR-3977	CLIP-seq
MIRT2552245	hsa-miR-409-3p	CLIP-seq
MIRT2248674	hsa-miR-4267	CLIP-seq
MIRT2552246	hsa-miR-4282	CLIP-seq
MIRT2248675	hsa-miR-4289	CLIP-seq
MIRT2552247	hsa-miR-4307	CLIP-seq
MIRT2552248	hsa-miR-4309	CLIP-seq
MIRT1067704	hsa-miR-4311	CLIP-seq
MIRT2552249	hsa-miR-4326	CLIP-seq
MIRT1067706	hsa-miR-4429	CLIP-seq
MIRT2552250	hsa-miR-4436b-3p	CLIP-seq
MIRT2552251	hsa-miR-452	CLIP-seq
MIRT2552252	hsa-miR-4653-3p	CLIP-seq
MIRT2552253	hsa-miR-4659a-5p	CLIP-seq
MIRT2552254	hsa-miR-4659b-5p	CLIP-seq
MIRT2552255	hsa-miR-4666-3p	CLIP-seq
MIRT2552256	hsa-miR-4676-3p	CLIP-seq
MIRT2552257	hsa-miR-4679	CLIP-seq
MIRT2552258	hsa-miR-4696	CLIP-seq
MIRT1067711	hsa-miR-4709-5p	CLIP-seq
MIRT2552259	hsa-miR-4715-3p	CLIP-seq
MIRT2552260	hsa-miR-4716-5p	CLIP-seq
MIRT2552261	hsa-miR-4719	CLIP-seq
MIRT2552262	hsa-miR-4728-3p	CLIP-seq
MIRT1067713	hsa-miR-4735-5p	CLIP-seq
MIRT1067714	hsa-miR-4742-3p	CLIP-seq
MIRT1067715	hsa-miR-4744	CLIP-seq
MIRT2552263	hsa-miR-4752	CLIP-seq
MIRT2552264	hsa-miR-4761-3p	CLIP-seq
MIRT2248677	hsa-miR-4768-5p	CLIP-seq
MIRT2552265	hsa-miR-4775	CLIP-seq
MIRT2552266	hsa-miR-4776-3p	CLIP-seq
MIRT1067716	hsa-miR-4778-5p	CLIP-seq
MIRT1067717	hsa-miR-4789-3p	CLIP-seq
MIRT2552267	hsa-miR-4798-3p	CLIP-seq
MIRT2248678	hsa-miR-483-3p	CLIP-seq
MIRT2552268	hsa-miR-494	CLIP-seq
MIRT2552269	hsa-miR-499a-5p	CLIP-seq
MIRT2248679	hsa-miR-506	CLIP-seq
MIRT1067719	hsa-miR-5096	CLIP-seq
MIRT2552270	hsa-miR-510	CLIP-seq
MIRT2552271	hsa-miR-512-5p	CLIP-seq
MIRT2552272	hsa-miR-513a-3p	CLIP-seq
MIRT2248680	hsa-miR-513a-5p	CLIP-seq
MIRT2552273	hsa-miR-548ae	CLIP-seq
MIRT2552274	hsa-miR-548aj	CLIP-seq
MIRT2552275	hsa-miR-548am	CLIP-seq
MIRT2248681	hsa-miR-548an	CLIP-seq
MIRT2552276	hsa-miR-548c-3p	CLIP-seq
MIRT1067721	hsa-miR-548v	CLIP-seq
MIRT2552277	hsa-miR-548x	CLIP-seq
MIRT2552278	hsa-miR-549	CLIP-seq
MIRT1067722	hsa-miR-576-5p	CLIP-seq
MIRT2552279	hsa-miR-579	CLIP-seq
MIRT1067723	hsa-miR-583	CLIP-seq
MIRT1067725	hsa-miR-605	CLIP-seq
MIRT2552280	hsa-miR-607	CLIP-seq
MIRT2248682	hsa-miR-634	CLIP-seq
MIRT2248683	hsa-miR-642b	CLIP-seq
MIRT2552281	hsa-miR-767-3p	CLIP-seq
MIRT2552282	hsa-miR-874	CLIP-seq
MIRT1067727	hsa-miR-92a	CLIP-seq
MIRT1067728	hsa-miR-92b	CLIP-seq
MIRT2552283	hsa-miR-938	CLIP-seq
MIRT2552284	hsa-miR-944	CLIP-seq
MIRT2552208	hsa-miR-1208	CLIP-seq
MIRT2552209	hsa-miR-1228	CLIP-seq
MIRT2552210	hsa-miR-1238	CLIP-seq
MIRT2248665	hsa-miR-124	CLIP-seq
MIRT1067681	hsa-miR-1276	CLIP-seq
MIRT2552213	hsa-miR-1296	CLIP-seq
MIRT2552214	hsa-miR-1324	CLIP-seq
MIRT2016432	hsa-miR-138	CLIP-seq
MIRT1067683	hsa-miR-139-5p	CLIP-seq
MIRT2248666	hsa-miR-140-5p	CLIP-seq
MIRT2552215	hsa-miR-155	CLIP-seq
MIRT2552216	hsa-miR-183	CLIP-seq
MIRT2552217	hsa-miR-19a	CLIP-seq
MIRT2552218	hsa-miR-19b	CLIP-seq
MIRT2552219	hsa-miR-2276	CLIP-seq
MIRT2552220	hsa-miR-2467-3p	CLIP-seq
MIRT2248667	hsa-miR-27a	CLIP-seq
MIRT2248668	hsa-miR-27b	CLIP-seq
MIRT2552221	hsa-miR-2909	CLIP-seq
MIRT2552222	hsa-miR-3117-5p	CLIP-seq
MIRT2552223	hsa-miR-3119	CLIP-seq
MIRT2552224	hsa-miR-3123	CLIP-seq
MIRT2552225	hsa-miR-3124-3p	CLIP-seq
MIRT2552226	hsa-miR-3129-3p	CLIP-seq
MIRT1067690	hsa-miR-3140-3p	CLIP-seq
MIRT2248669	hsa-miR-3143	CLIP-seq
MIRT1067691	hsa-miR-3145-5p	CLIP-seq
MIRT2552227	hsa-miR-3148	CLIP-seq
MIRT2552228	hsa-miR-3150a-5p	CLIP-seq
MIRT2552229	hsa-miR-3150b-5p	CLIP-seq
MIRT2016433	hsa-miR-3156-5p	CLIP-seq
MIRT2552230	hsa-miR-3157-3p	CLIP-seq
MIRT2552231	hsa-miR-3182	CLIP-seq
MIRT2552232	hsa-miR-3198	CLIP-seq
MIRT1067693	hsa-miR-320a	CLIP-seq
MIRT1067694	hsa-miR-320b	CLIP-seq
MIRT1067695	hsa-miR-320c	CLIP-seq
MIRT1067696	hsa-miR-320d	CLIP-seq
MIRT2552233	hsa-miR-337-3p	CLIP-seq
MIRT2552234	hsa-miR-342-3p	CLIP-seq
MIRT2552235	hsa-miR-3545-3p	CLIP-seq
MIRT2552236	hsa-miR-3613-3p	CLIP-seq
MIRT2552238	hsa-miR-3622b-5p	CLIP-seq
MIRT1067700	hsa-miR-3678-3p	CLIP-seq
MIRT2248672	hsa-miR-3680	CLIP-seq
MIRT2552239	hsa-miR-3685	CLIP-seq
MIRT1067701	hsa-miR-3686	CLIP-seq
MIRT2552240	hsa-miR-3688-3p	CLIP-seq
MIRT2552241	hsa-miR-3691-5p	CLIP-seq
MIRT2552242	hsa-miR-383	CLIP-seq
MIRT2552243	hsa-miR-384	CLIP-seq
MIRT1067703	hsa-miR-3908	CLIP-seq
MIRT2552244	hsa-miR-3919	CLIP-seq
MIRT2248673	hsa-miR-3977	CLIP-seq
MIRT2552245	hsa-miR-409-3p	CLIP-seq
MIRT2248674	hsa-miR-4267	CLIP-seq
MIRT2248675	hsa-miR-4289	CLIP-seq
MIRT2552247	hsa-miR-4307	CLIP-seq
MIRT2552248	hsa-miR-4309	CLIP-seq
MIRT1067704	hsa-miR-4311	CLIP-seq
MIRT2552249	hsa-miR-4326	CLIP-seq
MIRT1067706	hsa-miR-4429	CLIP-seq
MIRT2552250	hsa-miR-4436b-3p	CLIP-seq
MIRT2552251	hsa-miR-452	CLIP-seq
MIRT2552252	hsa-miR-4653-3p	CLIP-seq
MIRT2552253	hsa-miR-4659a-5p	CLIP-seq
MIRT2552254	hsa-miR-4659b-5p	CLIP-seq
MIRT2552255	hsa-miR-4666-3p	CLIP-seq
MIRT2552256	hsa-miR-4676-3p	CLIP-seq
MIRT2552257	hsa-miR-4679	CLIP-seq
MIRT2552258	hsa-miR-4696	CLIP-seq
MIRT1067711	hsa-miR-4709-5p	CLIP-seq
MIRT2552259	hsa-miR-4715-3p	CLIP-seq
MIRT2552260	hsa-miR-4716-5p	CLIP-seq
MIRT2552261	hsa-miR-4719	CLIP-seq
MIRT2552262	hsa-miR-4728-3p	CLIP-seq
MIRT1067713	hsa-miR-4735-5p	CLIP-seq
MIRT1067714	hsa-miR-4742-3p	CLIP-seq
MIRT1067715	hsa-miR-4744	CLIP-seq
MIRT2552263	hsa-miR-4752	CLIP-seq
MIRT2552264	hsa-miR-4761-3p	CLIP-seq
MIRT2248677	hsa-miR-4768-5p	CLIP-seq
MIRT2552265	hsa-miR-4775	CLIP-seq
MIRT2552266	hsa-miR-4776-3p	CLIP-seq
MIRT1067716	hsa-miR-4778-5p	CLIP-seq
MIRT1067717	hsa-miR-4789-3p	CLIP-seq
MIRT2552267	hsa-miR-4798-3p	CLIP-seq
MIRT2248678	hsa-miR-483-3p	CLIP-seq
MIRT2552268	hsa-miR-494	CLIP-seq
MIRT2552269	hsa-miR-499a-5p	CLIP-seq
MIRT2248679	hsa-miR-506	CLIP-seq
MIRT2552270	hsa-miR-510	CLIP-seq
MIRT2552271	hsa-miR-512-5p	CLIP-seq
MIRT2248680	hsa-miR-513a-5p	CLIP-seq
MIRT2552273	hsa-miR-548ae	CLIP-seq
MIRT2552274	hsa-miR-548aj	CLIP-seq
MIRT2552275	hsa-miR-548am	CLIP-seq
MIRT2248681	hsa-miR-548an	CLIP-seq
MIRT1067721	hsa-miR-548v	CLIP-seq
MIRT2552277	hsa-miR-548x	CLIP-seq
MIRT2552278	hsa-miR-549	CLIP-seq
MIRT1067722	hsa-miR-576-5p	CLIP-seq
MIRT1067723	hsa-miR-583	CLIP-seq
MIRT1067725	hsa-miR-605	CLIP-seq
MIRT2552280	hsa-miR-607	CLIP-seq
MIRT2248682	hsa-miR-634	CLIP-seq
MIRT2248683	hsa-miR-642b	CLIP-seq
MIRT2552281	hsa-miR-767-3p	CLIP-seq
MIRT2552282	hsa-miR-874	CLIP-seq
MIRT2552283	hsa-miR-938	CLIP-seq
MIRT2552284	hsa-miR-944	CLIP-seq

Show/Hide all (41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	12242332, 17428920, 25416956, 32296183
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA	32322062
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	32322062
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006607	Process	NLS-bearing protein import into nucleus	IDA	14645851
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006641	Process	Triglyceride metabolic process	IEA
GO:0006695	Process	Cholesterol biosynthetic process	IBA
GO:0006695	Process	Cholesterol biosynthetic process	IDA	32322062
GO:0006695	Process	Cholesterol biosynthetic process	IEA
GO:0006991	Process	Response to sterol depletion	IEA
GO:0008142	Function	Oxysterol binding	IDA	17428920, 32322062
GO:0008202	Process	Steroid metabolic process	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0010894	Process	Negative regulation of steroid biosynthetic process	IEA
GO:0016020	Component	Membrane	IEA
GO:0016126	Process	Sterol biosynthetic process	IEA
GO:0032868	Process	Response to insulin	IEA
GO:0032869	Process	Cellular response to insulin stimulus	IBA
GO:0032933	Process	SREBP signaling pathway	IBA
GO:0032933	Process	SREBP signaling pathway	IDA	12242332, 17428920, 32322062
GO:0032937	Component	SREBP-SCAP-Insig complex	IBA
GO:0032937	Component	SREBP-SCAP-Insig complex	IDA	12242332
GO:0033993	Process	Response to lipid	IEA
GO:0036316	Process	SREBP-SCAP complex retention in endoplasmic reticulum	IBA
GO:0036316	Process	SREBP-SCAP complex retention in endoplasmic reticulum	IDA	15899885
GO:0036316	Process	SREBP-SCAP complex retention in endoplasmic reticulum	IDA	15899885, 32322062
GO:0042472	Process	Inner ear morphogenesis	IEA
GO:0042474	Process	Middle ear morphogenesis	IEA
GO:0045542	Process	Positive regulation of cholesterol biosynthetic process	IDA	12177166
GO:0045717	Process	Negative regulation of fatty acid biosynthetic process	IEA
GO:0051604	Process	Protein maturation	IMP	21719679
GO:0060021	Process	Roof of mouth development	IEA
GO:0060363	Process	Cranial suture morphogenesis	IEA
GO:0070542	Process	Response to fatty acid	IEA
GO:0140311	Function	Protein sequestering activity	IDA	15899885, 32322062

MIM	HGNC	e!Ensembl
608660	20452	ENSG00000125629

Q9Y5U4

Protein name

Insulin-induced gene 2 protein (INSIG-2)

Protein function

Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR (PubMed:12242332, PubMed:16606821, PubMed:32322062). Acts as a negati

PDB

4J82 , 6M49 , 7ETW

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07281	INSIG	30 → 211	Insulin-induced protein (INSIG)	Family

Sequence

MAEGETESPGPKKCGPYISSVTSQSVNLMIRGVVLFFIGVFLALVLNLLQIQRNVTLFPP
DVIASIFSSAWWVPPCCGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINH
ASAKVDFDNNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQY
TSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE

Sequence length

225

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
GOUT	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERLIPIDEMIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (54)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Arteriosclerosis	Arteriosclerosis	BEFREE	19523229		★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	22355322		★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	Pubtator	22355322	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	19523229		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	20955599		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	18464289	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ductal	Ductal carcinoma	Pubtator	21443541	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	29514927	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathy, Familial Idiopathic	Cardiomyopathy	BEFREE	21443541		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	BEFREE	20920244		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular disease	Pubtator	20920244	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebrovascular Disorders	Cerebrovascular Disorders	BEFREE	20920244		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebrovascular Disorders	Cerebrovascular disorder	Pubtator	20920244	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognition disorder	Pubtator	32596317	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	18464289, 21443541, 26662938		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	LHGDN	18464289		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	26662938		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	18464289, 21443541	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	18989534		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	BEFREE	18989534, 19197259		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary heart disease	Coronary Heart Disease	BEFREE	18989534, 19740467		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	27623943		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	27623943		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	18840782, 32596317	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dyslipidemias	Dyslipidemias	BEFREE	18570692, 25607990		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dyslipidemias	Dyslipidemias	Pubtator	25607990	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ectrodactyly	Ectrodactyly	BEFREE	19223936		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ectrodactyly	Ectrodactyly	Pubtator	19223936	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Familial multiple trichoepitheliomata	Multiple Trichoepithelioma	BEFREE	18398047		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypercholesterolemia	Hypercholesterolemia	BEFREE	18570692		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypercholesterolemia	Hypercholesterolemia	Pubtator	32596317	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypercholesterolemia, Familial	Hypercholesterolemia	BEFREE	24987033		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	21443541	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Invasive Ductal Breast Carcinoma	Invasive Duct and Lobular Carcinoma	BEFREE	21443541		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	20955599		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	21443541		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	18464289, 21443541, 26662938		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome	Metabolic syndrome	Pubtator	18096054, 31144980, 35627229	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	18096054, 20877301, 22968099		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	19197259, 31630160		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	20083228, 22294722		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	24458218		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	16614226, 17137505, 17218508, 17218510, 17411394, 17471297, 17489846, 18003761, 18070740, 18096054, 18195716, 18239574, 18270535, 18325910, 18347269 View all (33 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	17137505, 17465681, 18070740, 18615239, 18839134, 19105843, 19360016, 19772594, 20028541, 20045156, 20920244, 21233811, 21544599, 21978759, 22513296 View all (7 more)	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity, Morbid	Obesity	BEFREE	18347269, 18615239		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	21443541		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	21443541	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral Vascular Diseases	Vascular Diseases	BEFREE	20920244		★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral Vascular Diseases	Peripheral vascular disease	Pubtator	20920244	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	BEFREE	20092643		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	20373477		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	35627229	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Split hand foot deformity 1	Split hand foot deformity	BEFREE	19223936		★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	33586351	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

INSIG2 (insulin induced gene 2)