SIDT2 (SID1 transmembrane family member 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51092 |
| Gene name | SID1 transmembrane family member 2 |
| Gene symbol | SIDT2 |
| Synonyms (NCBI Gene) |
CGI-40
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| Chromosome | 11 |
| Chromosome location | 11q23.3 |
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miRNA
miRNA information provided by mirtarbase database.
341
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
31
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8NBJ9 | ||||||||||
| Protein name | SID1 transmembrane family member 2 | ||||||||||
| Protein function | Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA), a process in which RNA or DNA is directly imported into lysosomes in an ATP-dependent manner, and degraded (PubMed:27046251, PubMed:27846 | ||||||||||
| PDB | 7Y63 , 7Y68 , 7Y69 , 8J6O , 8K10 , 8K11 , 8K12 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 832 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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