Gene Gene information from NCBI Gene database.
Entrez ID 51018
Gene name Ribosomal RNA processing 15 homolog
Gene symbol RRP15
Synonyms (NCBI Gene)
CGI-115KIAA0507
Chromosome 1
Chromosome location 1q41
Summary This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]
miRNA miRNA information provided by mirtarbase database.
613
miRTarBase ID miRNA Experiments Reference
MIRT022582 hsa-miR-124-3p Microarray 18668037
MIRT028500 hsa-miR-30a-5p Proteomics 18668040
MIRT029330 hsa-miR-26b-5p Microarray 19088304
MIRT031597 hsa-miR-16-5p Proteomics 18668040
MIRT1320221 hsa-let-7a CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
GO ID Ontology Definition Evidence Reference
GO:0000460 Process Maturation of 5.8S rRNA IBA
GO:0000470 Process Maturation of LSU-rRNA IBA
GO:0006364 Process RRNA processing IEA
GO:0030687 Component Preribosome, large subunit precursor IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611193 24255 ENSG00000067533
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y3B9
Protein name RRP15-like protein (Ribosomal RNA-processing protein 15)
PDB 8FKP , 8FKQ , 8FKR , 8FKS
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07890 Rrp15p 92 215 Rrp15p Family
Sequence
MAAAAPDSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDD
DAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEK
EKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKH
QKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLR
GMDGSTNETASSRKKPKAKQTEVKS
EEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESASDSDT
Sequence length 282
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CHRONIC OBSTRUCTIVE PULMONARY DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Colorectal Neoplasms Colorectal neoplasm Pubtator 36750557 Associate
★☆☆☆☆
Found in Text Mining only
Malignant Neoplasms Malignant Neoplasm BEFREE 28099941
★☆☆☆☆
Found in Text Mining only