RNF141 (ring finger protein 141)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 50862 |
| Gene name | Ring finger protein 141 |
| Gene symbol | RNF141 |
| Synonyms (NCBI Gene) |
RFP141ZFP26ZNF230
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| Chromosome | 11 |
| Chromosome location | 11p15.4|11p15 |
| Summary | The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic |
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miRNA
miRNA information provided by mirtarbase database.
645
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8WVD5 | ||||||||||
| Protein name | RING finger protein 141 (Zinc finger protein 230) | ||||||||||
| Protein function | May be involved in spermatogenesis. | ||||||||||
| PDB | 2ECN , 5XEK | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Isoform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients. {ECO:0000269|PubMed:11672448}. | ||||||||||
| Sequence |
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| Sequence length | 230 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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