Gene Gene information from NCBI Gene database.
Entrez ID 50861
Gene name Stathmin 3
Gene symbol STMN3
Synonyms (NCBI Gene)
SCLIP
Chromosome 20
Chromosome location 20q13.33
Summary This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubu
miRNA miRNA information provided by mirtarbase database.
934
miRTarBase ID miRNA Experiments Reference
MIRT049539 hsa-miR-92a-3p CLASH 23622248
MIRT048052 hsa-miR-197-3p CLASH 23622248
MIRT038576 hsa-miR-106b-3p CLASH 23622248
MIRT052675 hsa-miR-1260b CLASH 23622248
MIRT483505 hsa-miR-4787-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30
GO ID Ontology Definition Evidence Reference
GO:0001835 Process Blastocyst hatching IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
GO:0005737 Component Cytoplasm ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608362 15926 ENSG00000197457
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NZ72
Protein name Stathmin-3 (SCG10-like protein)
Protein function Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00836 Stathmin 39 175 Stathmin family Family
Tissue specificity TISSUE SPECIFICITY: Neuron specific.
Sequence
Sequence length 180
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
42
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ANKYLOSING SPONDYLITIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ATOPIC ECZEMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
AUTOIMMUNE DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
AUTOIMMUNE THYROID DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Adenocarcinoma Adenocarcinoma BEFREE 19258502
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 18959792 Associate
★☆☆☆☆
Found in Text Mining only
Dermatitis Atopic Atopic dermatitis Pubtator 33901562 Associate
★☆☆☆☆
Found in Text Mining only
Glioblastoma Glioblastoma BEFREE 25511414
★☆☆☆☆
Found in Text Mining only
Glioblastoma Glioblastoma Pubtator 25511414, 33169458 Associate
★☆☆☆☆
Found in Text Mining only
Glioblastoma Multiforme Glioblastoma BEFREE 25511414
★☆☆☆☆
Found in Text Mining only
Glioma Glioma BEFREE 25511414
★☆☆☆☆
Found in Text Mining only
Glioma Glioma Pubtator 25511414, 29460007, 33169458, 33504897, 34477880 Associate
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 19258502
★☆☆☆☆
Found in Text Mining only
Non-Small Cell Lung Carcinoma Lung carcinoma BEFREE 19258502
★☆☆☆☆
Found in Text Mining only