OPRM1 (opioid receptor mu 1)

Gene

• Entrez ID: 4988
• Gene name: Opioid receptor mu 1
• Gene symbol: OPRM1
• Synonyms (NCBI Gene): LMOR, M-OR-1, MOP, MOR, MOR1, OPRM
• Chromosome: 6
• Chromosome location: 6q25.2
• Summary: This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an importa

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs497332	C>A,G,T	Drug-response	Genic downstream transcript variant, intron variant
rs540825	A>C,G,T	Drug-response	Intron variant, synonymous variant, missense variant, genic downstream transcript variant, coding sequence variant
rs562859	C>A,G,T	Drug-response	Intron variant, synonymous variant, missense variant, genic downstream transcript variant, coding sequence variant
rs563649	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, genic downstream transcript variant
rs606545	G>A,C	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant, non coding transcript variant
rs623956	A>G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant, non coding transcript variant
rs650245	A>C,G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant
rs650825	G>A	Drug-response	Genic downstream transcript variant, intron variant
rs675026	A>C,G	Drug-response	Genic downstream transcript variant, coding sequence variant, intron variant, synonymous variant
rs677830	C>A,G,T	Drug-response, benign	Intron variant, missense variant, genic downstream transcript variant, stop gained, coding sequence variant
rs1799971	A>G	Drug-response, uncertain-significance	Intron variant, missense variant, non coding transcript variant, genic upstream transcript variant, coding sequence variant
rs2075572	G>C	Drug-response	Genic downstream transcript variant, intron variant
rs6912029	G>T	Drug-response	5 prime UTR variant, intron variant, coding sequence variant, upstream transcript variant, missense variant, genic upstream transcript variant
rs9282821	A>C,T	Drug-response	Intron variant, genic downstream transcript variant
rs9322446	G>A	Drug-response	5 prime UTR variant, genic upstream transcript variant, intron variant, genic downstream transcript variant
rs9479757	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs11575858	C>T	Drug-response	3 prime UTR variant, intron variant, non coding transcript variant, genic downstream transcript variant
rs17174794	C>G,T	Benign, drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, missense variant, coding sequence variant
rs17181192	T>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs41292890	C>T	Drug-response	Non coding transcript variant, genic upstream transcript variant, synonymous variant, intron variant, coding sequence variant, 5 prime UTR variant
rs60254893	C>G,T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs62638690	G>T	Drug-response	Non coding transcript variant, missense variant, genic downstream transcript variant, intron variant, coding sequence variant
rs71021021	TTTTTT>-,TTTTT,TTTTTTT,TTTTTTTTTT	Drug-response	Non coding transcript variant, downstream transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant
rs77696469	C>G,T	Drug-response	Non coding transcript variant, intron variant, 3 prime UTR variant, genic downstream transcript variant
rs78937301	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs113270588	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant
rs114492858	C>G,T	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, downstream transcript variant, genic downstream transcript variant
rs115788842	T>A	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant
rs139944762	C>A,T	Drug-response	Genic downstream transcript variant, 5 prime UTR variant, intron variant, genic upstream transcript variant
rs140560182	G>A	Drug-response	Genic downstream transcript variant, intron variant, downstream transcript variant
rs150821368	C>T	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant, downstream transcript variant
rs184553578	C>A,T	Drug-response	Missense variant, genic downstream transcript variant, non coding transcript variant, intron variant, coding sequence variant
rs186439043	C>T	Drug-response	Intron variant, coding sequence variant, missense variant, genic downstream transcript variant
rs199648369	C>G,T	Drug-response	Genic upstream transcript variant, coding sequence variant, 5 prime UTR variant, non coding transcript variant, intron variant, missense variant
rs199650905	C>T	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs199878364	C>T	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs199942335	G>A,C	Drug-response	Coding sequence variant, intron variant, missense variant, genic downstream transcript variant
rs200245799	G>A,C	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic downstream transcript variant
rs200512398	C>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, synonymous variant, stop gained, genic downstream transcript variant
rs200587105	G>A,C	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs200646591	G>A	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs200803187	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs200869983	C>T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, stop gained, genic downstream transcript variant
rs200915701	C>T	Drug-response	Genic upstream transcript variant, coding sequence variant, non coding transcript variant, intron variant, synonymous variant
rs201126701	G>A	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs201310502	C>G,T	Drug-response	Genic upstream transcript variant, coding sequence variant, non coding transcript variant, intron variant, missense variant
rs201518555	A>C,G	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs201750445	G>A,T	Drug-response	Intron variant, genic downstream transcript variant
rs201829386	C>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic downstream transcript variant
rs201858274	G>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, stop gained, missense variant, genic downstream transcript variant
rs370868117	C>T	Drug-response	Genic upstream transcript variant, coding sequence variant, 5 prime UTR variant, missense variant, non coding transcript variant, intron variant
rs377704466	G>A	Drug-response	Genic upstream transcript variant, intron variant
rs536957156	G>A,C	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs542615961	C>A,T	Drug-response	Non coding transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant, downstream transcript variant
rs546524303	G>A,T	Drug-response	Upstream transcript variant, genic upstream transcript variant, intron variant
rs552928147	A>C,G	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs557690438	A>G,T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs567300902	G>A	Drug-response	Non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, intron variant
rs571470402	A>C,G	Drug-response	Genic upstream transcript variant, intron variant, upstream transcript variant
rs573698787	C>T	Drug-response	Genic downstream transcript variant, intron variant, 3 prime UTR variant
rs577345039	C>G,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic upstream transcript variant
rs745863104	C>A,G,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic upstream transcript variant, synonymous variant
rs747345350	C>A,G	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs747772652	A>C,G	Drug-response	Intron variant, coding sequence variant, non coding transcript variant, missense variant, genic upstream transcript variant
rs749003633	C>T	Drug-response	Intron variant, stop gained, coding sequence variant, non coding transcript variant, genic downstream transcript variant
rs751081299	T>C,G	Drug-response	Intron variant, coding sequence variant, non coding transcript variant, missense variant, genic downstream transcript variant
rs765963522	C>T	Drug-response	Intron variant, coding sequence variant, synonymous variant, genic downstream transcript variant, non coding transcript variant
rs767783492	G>A,T	Drug-response	Genic downstream transcript variant, intron variant, coding sequence variant, missense variant
rs768115985	A>C	Drug-response	Genic downstream transcript variant, intron variant, stop lost, terminator codon variant
rs769540300	G>A	Drug-response	Intron variant, coding sequence variant, missense variant, genic downstream transcript variant, non coding transcript variant
rs769686797	G>A,C	Drug-response	Genic upstream transcript variant, intron variant
rs771278948	A>-,AA	Drug-response	Genic downstream transcript variant, intron variant
rs776184873	G>A	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant, genic upstream transcript variant
rs778238775	G>A,T	Drug-response	Non coding transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs778888827	T>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs898784845	A>G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant
rs914204741	C>G,T	Drug-response	Intron variant, genic downstream transcript variant
rs937431474	G>A,C	Drug-response	Genic downstream transcript variant, 5 prime UTR variant, intron variant, genic upstream transcript variant
rs947787494	C>A,G	Drug-response	Downstream transcript variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, intron variant
rs958018897	G>A	Drug-response	3 prime UTR variant, genic downstream transcript variant, intron variant, non coding transcript variant
rs968231224	C>T	Drug-response	3 prime UTR variant, genic downstream transcript variant, intron variant, non coding transcript variant
rs972892962	G>A	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant
rs979061434	C>G,T	Drug-response	Coding sequence variant, genic downstream transcript variant, missense variant, intron variant
rs984634670	G>A	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs986844324	C>G	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs994797893	C>T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, downstream transcript variant
rs1014331595	G>A,C,T	Drug-response	Genic downstream transcript variant, non coding transcript variant, intron variant, 3 prime UTR variant
rs1017227710	G>A	Drug-response	Genic downstream transcript variant, intron variant, 3 prime UTR variant
rs1033852015	A>G	Drug-response	Genic downstream transcript variant, genic upstream transcript variant, 5 prime UTR variant, intron variant
rs1160295304	C>T	Drug-response	Coding sequence variant, non coding transcript variant, genic downstream transcript variant, missense variant, intron variant
rs1160455955	G>A	Drug-response	Genic downstream transcript variant, downstream transcript variant, intron variant
rs1169090293	A>G	Drug-response	Coding sequence variant, non coding transcript variant, genic downstream transcript variant, intron variant, downstream transcript variant, synonymous variant
rs1178930557	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1183268180	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1190969003	C>T	Drug-response	Non coding transcript variant, synonymous variant, coding sequence variant, intron variant, genic upstream transcript variant
rs1201764699	C>T	Drug-response	Intron variant, 5 prime UTR variant, genic downstream transcript variant, genic upstream transcript variant
rs1210793358	A>G	Drug-response	Genic downstream transcript variant, coding sequence variant, missense variant, non coding transcript variant, intron variant
rs1225445157	C>T	Drug-response	Non coding transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant
rs1230347496	G>A	Drug-response	5 prime UTR variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1245588858	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1247954412	C>A	Drug-response	Coding sequence variant, intron variant, missense variant, upstream transcript variant, genic upstream transcript variant, 5 prime UTR variant
rs1252162127	T>A,C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant
rs1260131147	A>G	Drug-response	5 prime UTR variant, genic upstream transcript variant, genic downstream transcript variant, intron variant
rs1266748899	G>A	Drug-response	5 prime UTR variant, genic downstream transcript variant, genic upstream transcript variant, intron variant
rs1280372606	C>G,T	Drug-response	Intron variant, genic downstream transcript variant
rs1290858635	T>A,C	Drug-response	Non coding transcript variant, genic downstream transcript variant, coding sequence variant, intron variant, missense variant
rs1291536093	A>G,T	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant, genic downstream transcript variant
rs1292119568	T>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs1293588318	G>A,C	Drug-response	Intron variant, 5 prime UTR variant, genic upstream transcript variant, genic downstream transcript variant
rs1297476429	C>A,T	Drug-response	5 prime UTR variant, non coding transcript variant, genic upstream transcript variant, coding sequence variant, intron variant, missense variant
rs1304233202	C>T	Drug-response	3 prime UTR variant, non coding transcript variant, downstream transcript variant, intron variant, genic downstream transcript variant
rs1312664080	G>A,C	Drug-response	Missense variant, 5 prime UTR variant, genic upstream transcript variant, intron variant, upstream transcript variant, coding sequence variant
rs1326499420	A>C,T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant
rs1339199018	T>C,G	Drug-response	3 prime UTR variant, intron variant, non coding transcript variant, genic downstream transcript variant
rs1340096837	A>C,G	Drug-response	5 prime UTR variant, genic downstream transcript variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1347406881	C>A	Drug-response	Genic downstream transcript variant, non coding transcript variant, missense variant, coding sequence variant, intron variant
rs1347537120	A>C,T	Drug-response	Genic downstream transcript variant, intron variant
rs1348736608	C>T	Drug-response	Downstream transcript variant, genic downstream transcript variant, non coding transcript variant, 3 prime UTR variant, intron variant
rs1357614491	C>A,T	Drug-response	Downstream transcript variant, genic downstream transcript variant, non coding transcript variant, coding sequence variant, missense variant, intron variant
rs1358871698	C>A,T	Drug-response	Genic downstream transcript variant, intron variant
rs1368893702	G>A	Drug-response	5 prime UTR variant, genic upstream transcript variant, intron variant
rs1373421578	G>A	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant
rs1376751124	C>T	Drug-response	Genic downstream transcript variant, intron variant
rs1377052121	A>C,G	Drug-response	3 prime UTR variant, genic downstream transcript variant, non coding transcript variant, intron variant
rs1396848779	T>A,C	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1399307406	G>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs1411722881	C>-	Drug-response	Intron variant, frameshift variant, genic upstream transcript variant, non coding transcript variant, 5 prime UTR variant, coding sequence variant
rs1411786454	T>C,G	Drug-response	Intron variant, genic downstream transcript variant, non coding transcript variant, missense variant, coding sequence variant
rs1421882124	T>C	Drug-response	5 prime UTR variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1437740130	T>C,G	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant, non coding transcript variant
rs1442486722	A>-,AA	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant, non coding transcript variant
rs1465337438	C>A,T	Drug-response	5 prime UTR variant, coding sequence variant, intron variant, genic upstream transcript variant, missense variant, non coding transcript variant
rs1469997583	C>T	Drug-response	5 prime UTR variant, intron variant, coding sequence variant, genic upstream transcript variant, synonymous variant, upstream transcript variant
rs1482103571	C>G,T	Drug-response	Intron variant, non coding transcript variant, missense variant, coding sequence variant, genic upstream transcript variant
rs1562384714	G>A,T	Drug-response	Upstream transcript variant, 5 prime UTR variant, genic upstream transcript variant, intron variant
rs1562387533	G>C	Drug-response	Genic upstream transcript variant, intron variant
rs1583105193	C>T	Drug-response	Upstream transcript variant
rs1583105350	A>G	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105355	G>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105431	G>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105433	T>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105465	C>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105485	A>G	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105621	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105642	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105657	A>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105863	A>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105959	TC>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105979	A>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106074	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106084	G>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106153	G>T	Drug-response	Intron variant, genic upstream transcript variant
rs1583106204	G>T	Drug-response	Intron variant, genic upstream transcript variant
rs1583106304	AT>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583168957	C>A	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583168963	T>C	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583168972	C>A	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583169018	T>C	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583169368	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583169385	C>A	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583169899	T>A	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, upstream transcript variant, coding sequence variant, genic upstream transcript variant
rs1583169988	G>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170034	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170107	G>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170298	G>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, upstream transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170659	G>A	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170710	G>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170716	C>T	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170728	T>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583171311	C>T	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583171446	C>T	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172139	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172146	C>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172783	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173066	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173231	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173318	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173471	G>C	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173482	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173537	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173570	C>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173845	GT>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173935	A>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583173984	G>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174062	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174146	C>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174701	C>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174793	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174921	G>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174969	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583175062	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583453568	T>C	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583453631	A>T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583454341	T>G	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583454446	A>C	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583454910	A>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583454933	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583454962	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455028	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455134	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455554	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456447	G>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456563	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456779	T>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456891	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456915	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456966	A>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457176	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457200	G>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457555	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457650	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583458111	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583458841	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459163	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459338	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459748	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459767	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459826	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459907	T>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460328	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460436	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460633	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460834	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460886	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460948	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461106	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461135	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461155	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461469	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461542	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461992	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583462573	G>T	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583462707	C>T	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583462789	T>C	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463133	T>-	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463193	G>A	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463210	G>T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463246	A>C,T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583475145	A>T	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475171	T>G	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475226	T>C	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475860	A>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583476221	T>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583476950	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477398	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477578	G>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477595	G>C	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477806	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478324	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478475	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478736	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479242	A>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479373	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479561	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583479779	T>-	Drug-response	Intron variant, genic downstream transcript variant
rs1583480107	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583480309	T>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583483080	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583483141	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583484799	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583484841	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485058	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485109	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485227	T>G	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant, stop gained
rs1583485720	T>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486157	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486285	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486994	T>C	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583487598	G>T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant, stop gained
rs1583487978	CT>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583488922	T>C	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489027	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489096	G>A	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489204	T>A	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583489460	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489837	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489871	T>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489915	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490024	G>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490295	T>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490437	A>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490466	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490491	T>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490520	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490544	T>G	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490805	AA>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490952	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491015	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491131	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491203	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491221	G>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491244	A>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491281	A>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491311	A>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491360	T>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491388	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491465	C>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491549	A>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492013	T>C	Drug-response	Missense variant, intron variant, 3 prime UTR variant, genic downstream transcript variant, coding sequence variant
rs1583492207	G>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492371	C>G	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492385	A>G	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492649	A>-	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant
rs1583492838	C>-	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant
rs1583498192	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498227	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498253	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583498287	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498344	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498416	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498470	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498695	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583498735	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498860	A>-	Drug-response	Intron variant, genic downstream transcript variant
rs1583498941	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498961	T>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498980	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499039	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583499129	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583499200	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499255	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583499305	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499402	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499617	C>-	Drug-response	Intron variant, genic downstream transcript variant, coding sequence variant, frameshift variant
rs1583499951	C>A	Drug-response	Intron variant, genic downstream transcript variant, synonymous variant, coding sequence variant
rs1583500066	G>A	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583500127	T>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583500706	T>C	Drug-response	Intron variant, genic downstream transcript variant, synonymous variant, coding sequence variant
rs1583502117	T>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583502202	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583502383	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1583502552	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1583576485	T>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583576504	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583576560	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583576581	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583576770	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583577388	A>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583577432	A>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583577918	A>C	Drug-response	Terminator codon variant, intron variant, genic downstream transcript variant, stop lost
rs1583578066	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583578847	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant
rs1583579146	C>-	Drug-response	Downstream transcript variant, intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579223	T>G	Drug-response	Downstream transcript variant, synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579274	T>C	Drug-response	Downstream transcript variant, synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579471	G>A	Drug-response	Downstream transcript variant, synonymous variant, intron variant, terminator codon variant, non coding transcript variant, genic downstream transcript variant
rs1583579544	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579747	T>-	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579780	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579976	A>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580011	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580059	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580161	A>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580176	A>G	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580562	A>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580623	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580736	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581065	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581242	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581365	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581395	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581810	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582181	C>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582271	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582311	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582329	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582348	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582470	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582588	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582674	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583367	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583459	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583588	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583598	A>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583705	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583861	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583986	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584064	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584184	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584208	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584227	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584237	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584273	G>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584685	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584843	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584876	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585064	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585088	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585235	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583590926	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583591171	G>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583591180	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583591643	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583618074	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583618090	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583618097	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583618112	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583618119	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583618157	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618505	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583618625	C>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618663	C>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618684	A>C	Drug-response	Splice acceptor variant, intron variant, genic downstream transcript variant
rs1583618696	C>T	Drug-response	Synonymous variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583618957	G>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583618998	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619099	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619112	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619173	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619209	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619229	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619237	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619245	TT>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619252	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619270	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619276	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619322	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619413	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619421	A>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619449	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619477	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619560	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619673	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619742	TC>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619765	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619797	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619824	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619875	AA>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619933	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619977	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620013	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620060	TT>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620067	C>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620083	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620088	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620109	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620169	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620181	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620216	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620267	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620288	C>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620348	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620362	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620394	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620400	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620413	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620422	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620432	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620448	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620546	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620663	G>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620668	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620690	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT054667	hsa-miR-103a-3p	qRT-PCR	24302561
MIRT054667	hsa-miR-103a-3p	qRT-PCR	24302561
MIRT054668	hsa-miR-107	qRT-PCR	24302561
MIRT054668	hsa-miR-107	qRT-PCR	24302561
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT732142	hsa-miR-16-5p	Luciferase reporter assay, qRT-PCR, Western blot	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assay, qRT-PCR	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assay, qRT-PCR	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assay, qRT-PCR	26052934
MIRT734252	hsa-let-7d-5p	Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), qRT-PCR	34124049
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT1204525	hsa-miR-3669	CLIP-seq
MIRT1204526	hsa-miR-4453	CLIP-seq
MIRT1204527	hsa-miR-4538	CLIP-seq
MIRT1204528	hsa-miR-493	CLIP-seq
MIRT1204529	hsa-miR-3622b-5p	CLIP-seq
MIRT1204525	hsa-miR-3669	CLIP-seq
MIRT1204530	hsa-miR-4725-5p	CLIP-seq
MIRT1204531	hsa-miR-4786-5p	CLIP-seq
MIRT1204532	hsa-miR-504	CLIP-seq
MIRT1204533	hsa-miR-769-5p	CLIP-seq
MIRT1204534	hsa-miR-1912	CLIP-seq
MIRT1204535	hsa-miR-3128	CLIP-seq
MIRT1204529	hsa-miR-3622b-5p	CLIP-seq
MIRT1204536	hsa-miR-4470	CLIP-seq
MIRT1204537	hsa-miR-4720-5p	CLIP-seq
MIRT1204538	hsa-miR-4799-3p	CLIP-seq
MIRT2585310	hsa-miR-4691-5p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
JUN	Unknown	18523482
NFKB1	Unknown	18523482
REST	Repression	15322094;19913583
SP1	Activation	11675004
SP1	Unknown	17990281
SP3	Activation	11675004
STAT1	Activation	15448191
STAT3	Activation	15448191
STAT6	Unknown	20828825
YY1	Unknown	17990281

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001965	Function	G-protein alpha-subunit binding	IBA
GO:0001965	Function	G-protein alpha-subunit binding	IDA	20214800
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	ISS
GO:0004979	Function	Beta-endorphin receptor activity	IBA
GO:0004979	Function	Beta-endorphin receptor activity	IEA
GO:0004979	Function	Beta-endorphin receptor activity	IMP	9689128
GO:0004985	Function	G protein-coupled opioid receptor activity	IEA
GO:0005245	Function	Voltage-gated calcium channel activity	ISS
GO:0005515	Function	Protein binding	IPI	14573758, 19788913, 20214800, 23597562, 23840749, 28298427, 32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005768	Component	Endosome	ISS
GO:0005783	Component	Endoplasmic reticulum	TAS	9242668
GO:0005794	Component	Golgi apparatus	TAS	9242668
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS	7905839, 9242668
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IDA	20214800
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007187	Process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	TAS	7905839
GO:0007193	Process	Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	20525224
GO:0007197	Process	Adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	ISS
GO:0007200	Process	Phospholipase C-activating G protein-coupled receptor signaling pathway	ISS
GO:0007218	Process	Neuropeptide signaling pathway	IBA
GO:0007600	Process	Sensory perception	NAS	9689128
GO:0008285	Process	Negative regulation of cell population proliferation	TAS	2159143
GO:0008528	Function	G protein-coupled peptide receptor activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0019233	Process	Sensory perception of pain	IBA
GO:0019233	Process	Sensory perception of pain	ISS
GO:0030424	Component	Axon	IEA
GO:0030424	Component	Axon	ISS
GO:0030425	Component	Dendrite	IEA
GO:0030425	Component	Dendrite	ISS
GO:0031681	Function	G-protein beta-subunit binding	IBA
GO:0038003	Process	G protein-coupled opioid receptor signaling pathway	IBA
GO:0038003	Process	G protein-coupled opioid receptor signaling pathway	ISS
GO:0038047	Function	Morphine receptor activity	IBA
GO:0038047	Function	Morphine receptor activity	ISS
GO:0042923	Function	Neuropeptide binding	IBA
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IBA
GO:0043204	Component	Perikaryon	IEA
GO:0045019	Process	Negative regulation of nitric oxide biosynthetic process	IDA	20525224
GO:0045202	Component	Synapse	IEA
GO:0048149	Process	Behavioral response to ethanol	IMP	21039637
GO:0050769	Process	Positive regulation of neurogenesis	ISS
GO:0051481	Process	Negative regulation of cytosolic calcium ion concentration	IDA	20525224
GO:0061358	Process	Negative regulation of Wnt protein secretion	IMP	20214800
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	ISS
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0071315	Process	Cellular response to morphine	IEA
GO:0080135	Process	Regulation of cellular response to stress	IMP	21039637
GO:2000310	Process	Regulation of NMDA receptor activity	ISS

Other IDs

• MIM: 600018
• HGNC: 8156
• e!Ensembl: ENSG00000112038

Protein

• UniProt ID: P35372
• Protein name: Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)
• Protein function: Receptor for endogenous opioids such as beta-endorphin and endomorphin (PubMed:10529478, PubMed:12589820, PubMed:7891175, PubMed:7905839, PubMed:7957926, PubMed:9689128). Receptor for natural and synthetic opioids including morphine, heroin, DAM
• PDB: 8EF5, 8EF6, 8EFB, 8EFL, 8EFO, 8EFQ, 8F7Q, 8F7R, 8K9K, 8K9L, 9MQH, 9MQI, 9MQJ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00001	7tm_1	87 → 338	7 transmembrane receptor (rhodopsin family)	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in brain. Isoform 16 and isoform 17 are detected in brain. {ECO:0000269|PubMed:16580639}.
• Sequence:

  MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
  PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
  STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
  RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
  FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
  YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
  EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP

• Sequence length: 400

Pathways

KEGG:

Neuroactive ligand-receptor interaction
Hormone signaling
Estrogen signaling pathway
Morphine addiction

Reactome:

Opioid Signalling
G-protein activation
Peptide ligand-binding receptors
G alpha (i) signalling events
Interleukin-4 and Interleukin-13 signaling

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AMPHETAMINE OR RELATED ACTING SYMPATHOMIMETIC ABUSE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AMPHETAMINE-RELATED DISORDERS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ASTHMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATOPIC ECZEMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHILDHOOD ONSET ASTHMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC LYMPHOCYTIC LEUKEMIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONSTIPATION	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEPRESSION, POSTPARTUM	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEPRESSIVE DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DYSKINESIAS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DYSKINETIC SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EPILEPSY	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEPATIC ENCEPHALOPATHY	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEPATITIS C	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERALGESIA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPOTENSION, ORTHOSTATIC	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
IDIOPATHIC OSTEONECROSIS OF THE FEMORAL HEAD	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENTAL DEPRESSION	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MOVEMENT DISORDERS	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NAUSEA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NONORGANIC PSYCHOSIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Opioid dependence, susceptibility to, 1	drug response; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POST-TRAUMATIC STRESS DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRURITUS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSYCHOSES, SUBSTANCE-INDUCED	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSYCHOTIC DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA 12	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEIZURES	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Tramadol response	drug response; Uncertain significance; Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	28650467		★☆☆☆☆ Found in Text Mining only
Adult Acute Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	28650467		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	30152845	Associate	★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	27022229, 27682590		★☆☆☆☆ Found in Text Mining only
Anorexia	Anorexia	BEFREE	29486102		★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety Disorder	BEFREE	15048644, 15584875, 29576267		★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety disorder	Pubtator	30656852, 31553235	Associate	★☆☆☆☆ Found in Text Mining only
Anxiety Disorders	Anxiety Disorder	BEFREE	15048644, 15584875, 23658070, 29576267		★☆☆☆☆ Found in Text Mining only
Arthritis	Arthritis	BEFREE	17530644, 30053832		★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	Pubtator	36395102	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Atherosclerosis	Atherosclerosis	Pubtator	25613305	Associate	★☆☆☆☆ Found in Text Mining only
Attention Deficit Disorder with Hyperactivity	Attention deficit hyperactivity disorder	Pubtator	22841130	Associate	★☆☆☆☆ Found in Text Mining only
Attention deficit hyperactivity disorder	Attention Deficit Hyperactivity Disorder	BEFREE	22841130		★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	25625371, 28369738, 29331800, 30242222		★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	BEFREE	25625371, 30242222		★☆☆☆☆ Found in Text Mining only
Awakening Epilepsy	Epilepsy	CTD_human_DG	2415332		★☆☆☆☆ Found in Text Mining only
Ballismus	Ballismus	CTD_human_DG	16435402		★☆☆☆☆ Found in Text Mining only
Binge Drinking	Binge drinking	Pubtator	22143634	Associate	★☆☆☆☆ Found in Text Mining only
Binge Eating Disorder	Binge eating disorder	Pubtator	19282821	Associate	★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	BEFREE	29497192		★☆☆☆☆ Found in Text Mining only
Breast adenocarcinoma	Breast Adenocarcinoma	BEFREE	18523482		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	22433205, 25239082, 25618602		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	25239082, 25618602, 35727214, 36672750, 36942908	Associate	★☆☆☆☆ Found in Text Mining only
Bronchioloalveolar Adenocarcinoma	Lung adenocarcinoma	BEFREE	22343475		★☆☆☆☆ Found in Text Mining only
Bulimia	Bulimia	BEFREE	28594147		★☆☆☆☆ Found in Text Mining only
Cancer Pain	Cancer	Pubtator	17156920, 23803057, 28346387, 30700073, 35710811	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	10656608, 22343475, 24662916, 24786234		★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	27682590	Associate	★☆☆☆☆ Found in Text Mining only
Carcinomatosis of peritoneal cavity	Peritoneal Carcinomatosis	BEFREE	22913923		★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Cerebral Infarction	BEFREE	30024618		★☆☆☆☆ Found in Text Mining only
Cerebral Small Vessel Diseases	Cerebral microangiopathy	Pubtator	25613305	Associate	★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	BEFREE	28650467		★☆☆☆☆ Found in Text Mining only
Cholestasis	Cholestasis	BEFREE	18709298, 30419252		★☆☆☆☆ Found in Text Mining only
Cholestasis	Cholelithiasis	Pubtator	18709298	Associate	★☆☆☆☆ Found in Text Mining only
Choroid Plexus Papilloma	Choroid Plexus Papilloma	BEFREE	23566343		★☆☆☆☆ Found in Text Mining only
Chronic heart failure	Heart Failure	BEFREE	29935580		★☆☆☆☆ Found in Text Mining only
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	GWASCAT_DG	24292274, 28165464		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	GWASDB_DG	24292274		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chronic Pain	Chronic pain	Pubtator	23803057, 30700073, 32098316, 36672750, 36942908	Associate	★☆☆☆☆ Found in Text Mining only
Clonic Seizures	Clonic Seizures	CTD_human_DG	1675896, 18042875		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	35983971, 37217861	Associate	★☆☆☆☆ Found in Text Mining only
Complex partial seizures	Seizure	CTD_human_DG	1675896, 18042875		★☆☆☆☆ Found in Text Mining only
Congenital chromosomal disease	Congenital Chromosomal Disease	BEFREE	52973, 6875304, 7426426		★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	20413378, 29935580		★☆☆☆☆ Found in Text Mining only
Constipation	Constipation	Pubtator	36942908	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Contact Dermatitis	Dermatitis	BEFREE	31568781		★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	20413378		★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	BEFREE	20413378		★☆☆☆☆ Found in Text Mining only
Coronary heart disease	Coronary Heart Disease	BEFREE	20413378		★☆☆☆☆ Found in Text Mining only
Cyclical vomiting syndrome (disorder)	Cyclical Vomiting Syndrome	BEFREE	28349993		★☆☆☆☆ Found in Text Mining only
Cystitis Interstitial	Interstitial cystitis	Pubtator	30973927	Associate	★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	31190964		★☆☆☆☆ Found in Text Mining only
Dental Caries	Dental caries	Pubtator	30973902	Associate	★☆☆☆☆ Found in Text Mining only
Depression, Postpartum	Mental Depression	PSYGENET_DG	21459516		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Depressive disorder	Mental Depression	PSYGENET_DG	19596019, 21703297, 24766998, 25286107		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Depressive disorder	Mental Depression	BEFREE	24766998, 26228411, 28935293		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Depressive Disorder	Major depressive disorder	Pubtator	26228411, 30656852, 31553235, 32492095	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Dermatitis, Atopic	Dermatitis	BEFREE	15724090, 25281794		★☆☆☆☆ Found in Text Mining only
Dermatologic disorders	Dermatologic Disorders	BEFREE	29211767		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	16140553, 18518884		★☆☆☆☆ Found in Text Mining only
Disruptive Impulse Control and Conduct Disorders	Disruptive, impulse control, and conduct disorders	Pubtator	31553235	Associate	★☆☆☆☆ Found in Text Mining only
Disruptive, Impulse Control, and Conduct Disorders	Impulse control disorder	BEFREE	30444952		★☆☆☆☆ Found in Text Mining only
Disturbance in mood	Mood Disorder	BEFREE	15007373		★☆☆☆☆ Found in Text Mining only
Dyskinetic syndrome	Dyskinetic Syndrome	BEFREE	16435402, 30837649		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Dyskinetic syndrome	Dyskinetic Syndrome	CTD_human_DG	16435402		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Dyslexia	Dyslexia	Pubtator	37667328	Associate	★☆☆☆☆ Found in Text Mining only
Dysphoric mood	Mood Disorder	BEFREE	15584875		★☆☆☆☆ Found in Text Mining only
Dysphoric mood	Mood Disorder	PSYGENET_DG	15584875		★☆☆☆☆ Found in Text Mining only
Dystonia Disorders	Dystonia	BEFREE	29150865		★☆☆☆☆ Found in Text Mining only
Eczema	Eczema	BEFREE	15724090, 25281794		★☆☆☆☆ Found in Text Mining only
Encephalitis	Encephalitis	Pubtator	24413261, 27400929	Associate	★☆☆☆☆ Found in Text Mining only
Encephalitis	Encephalitis	BEFREE	27400929		★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	BEFREE	15299092, 28256208		★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	Pubtator	28256208	Associate	★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	CTD_human_DG	2415332		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Epilepsy, Cryptogenic	Epilepsy	CTD_human_DG	2415332		★☆☆☆☆ Found in Text Mining only
Epilepsy, Generalized	Epilepsy	LHGDN	12221164		★☆☆☆☆ Found in Text Mining only
Epilepsy, Temporal Lobe	Epilepsy	BEFREE	18509280, 30257385		★☆☆☆☆ Found in Text Mining only
Epileptic drop attack	Hypotonic seizures	CTD_human_DG	1675896, 18042875		★☆☆☆☆ Found in Text Mining only
Etat Marbre	Status marmoratus	CTD_human_DG	20298714		★☆☆☆☆ Found in Text Mining only
Fanconi Anemia	Fanconi Anemia	BEFREE	3755219, 4018790		★☆☆☆☆ Found in Text Mining only
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	Anemia	BEFREE	3755219, 4018790		★☆☆☆☆ Found in Text Mining only
Fulminant Hepatic Failure with Cerebral Edema	Fulminant Hepatic Failure With Cerebral Edema	CTD_human_DG	11991257		★☆☆☆☆ Found in Text Mining only
Functional Gastrointestinal Disorders	Functional Gastrointestinal Disorders	BEFREE	15324704, 15588800		★☆☆☆☆ Found in Text Mining only
Gastroparesis	Gastroparesis	BEFREE	30934667		★☆☆☆☆ Found in Text Mining only
Generalized seizures	Seizure	CTD_human_DG	1675896, 18042875		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	31423502		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	31423502		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	33315125	Associate	★☆☆☆☆ Found in Text Mining only
Graft-vs-Host Disease	Graft-Vs-Host Disease	BEFREE	30353554		★☆☆☆☆ Found in Text Mining only
Headache	Headache	Pubtator	22752568	Associate	★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	BEFREE	20413378		★☆☆☆☆ Found in Text Mining only
Hemiballismus	Hemiballismus	CTD_human_DG	16435402		★☆☆☆☆ Found in Text Mining only
Hepatic Coma	Hepatic Coma	CTD_human_DG	11991257		★☆☆☆☆ Found in Text Mining only
Hepatic Encephalopathy	Hepatic Encephalopathy	CTD_human_DG	11991257		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatic Stupor	Hepatic Stupor	CTD_human_DG	11991257		★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	BEFREE	28577871		★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	31755934		★☆☆☆☆ Found in Text Mining only
Idiopathic generalized epilepsy	Epilepsy	BEFREE	12221164, 17054695		★☆☆☆☆ Found in Text Mining only
Immunologic Deficiency Syndromes	Immunologic Deficiency Syndromes	BEFREE	19164126		★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	23560613		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	16299031		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	16299031	Associate	★☆☆☆☆ Found in Text Mining only
Intervertebral disc disease	Intervertebral disc disease	Pubtator	22815498	Associate	★☆☆☆☆ Found in Text Mining only
Intervertebral Disc Displacement	Intervertebral disc displacement	Pubtator	22815498, 24884878	Associate	★☆☆☆☆ Found in Text Mining only
Intestinal Diseases	Intestinal Diseases	BEFREE	29016552		★☆☆☆☆ Found in Text Mining only
Intestinal Neoplasms	Intestinal neoplasm	Pubtator	31773688	Associate	★☆☆☆☆ Found in Text Mining only
Irritable Bowel Syndrome	Irritable bowel syndrome	Pubtator	31336406	Stimulate	★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	BEFREE	31187646		★☆☆☆☆ Found in Text Mining only
Jacksonian Seizure	Jacksonian Seizure	CTD_human_DG	1675896, 18042875		★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	28650467	Associate	★☆☆☆☆ Found in Text Mining only
Lingual-Facial-Buccal Dyskinesia	Orofacial dyskinesia	CTD_human_DG	16435402		★☆☆☆☆ Found in Text Mining only
Lip and Oral Cavity Carcinoma	Lip and Oral Cavity Carcinoma	BEFREE	24963050		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	22796345, 23900681, 26808085, 30915986, 30928385		★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis Biliary	Liver cirrhosis	Pubtator	18709298	Associate	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	22003224, 24662916, 24920011, 30455395	Associate	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	35983971	Associate	★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	20107485		★☆☆☆☆ Found in Text Mining only
Lymphoma, T-Cell, Cutaneous	Lymphoma	BEFREE	20107485, 28627461		★☆☆☆☆ Found in Text Mining only
Major Depressive Disorder	Mental Depression	BEFREE	20194481, 23658070, 24766998, 29331800, 30553825, 30677547		★☆☆☆☆ Found in Text Mining only
Malignant Bone Neoplasm	Malignant Bone Neoplasm	BEFREE	28415063, 28891868, 29482000, 31271770		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	22433205, 25239082, 25618602		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	23900681		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	22343475, 24662916, 24786234		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of mouth	Malignant neoplasm of mouth	BEFREE	24963050		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	27682590		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	21209234, 22796345, 24963050, 25618602, 26043235, 28092646, 28456745, 31371700, 31755291		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	17897634, 29577418	Associate	★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	29577418		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	PSYGENET_DG	19596019, 21703297, 24766998, 25286107		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mental Depression	Mental Depression	BEFREE	24766998, 26228411, 28935293		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mental disorders	Mental Disorders	BEFREE	18250953, 22925223		★☆☆☆☆ Found in Text Mining only
Migraine Disorders	Migraine	BEFREE	22752568, 28349993, 31279240		★☆☆☆☆ Found in Text Mining only
Migraine Disorders	Migraine	Pubtator	22752568	Associate	★☆☆☆☆ Found in Text Mining only
Migraine with Aura	Migraine with Aura	BEFREE	22752568		★☆☆☆☆ Found in Text Mining only
Mild cognitive disorder	Cognitive disorder	BEFREE	27838450		★☆☆☆☆ Found in Text Mining only
Mixed anxiety and depressive disorder	Mixed Anxiety And Depressive Disorder	BEFREE	30656852		★☆☆☆☆ Found in Text Mining only
Movement Disorders	Movement Disorders	CTD_human_DG	20298714		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Movement Disorders	Movement Disorders	BEFREE	29150865		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mucopolysaccharidosis, MPS-IV-A	Mucopolysaccharidosis	BEFREE	27955919, 29526614		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	20955200, 22343475, 22796345, 23900681, 24662916, 29867508		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	11869806, 12106667, 15448191, 15901846, 16580639, 16963028, 18596614, 20197280, 20615556, 20643133, 21308796, 22375000, 23608241, 24654606, 27292014, 28627461, 9366465		★☆☆☆☆ Found in Text Mining only
NEUROTICISM	Neuroticism	BEFREE	25308352, 29980755		★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	15545974, 22343475, 24662916, 28291693		★☆☆☆☆ Found in Text Mining only
Nonorganic psychosis	Nonorganic Psychosis	BEFREE	15542732		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonorganic psychosis	Nonorganic Psychosis	PSYGENET_DG	15542732, 16402083		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Obesity	Obesity	BEFREE	19008867, 23337944, 23670889, 28133443, 29662095		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Obesity	Obesity	Pubtator	19008867, 23917806, 29662095	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Obesity, Morbid	Obesity	BEFREE	29655552		★☆☆☆☆ Found in Text Mining only
Obsessive-Compulsive Disorder	Obsessive-Compulsive Disorder	BEFREE	15108189		★☆☆☆☆ Found in Text Mining only
Oral Dyskinesia	Oral Dyskinesia	CTD_human_DG	16435402		★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	32098316	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian Diseases	Ovarian diseases	Pubtator	16815388	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	35033381, 36988399	Associate	★☆☆☆☆ Found in Text Mining only
Painful Bladder Syndrome	Interstitial cystitis	BEFREE	28554003		★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	27682590		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	27682590	Associate	★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	30444952		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	35960604	Associate	★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	BEFREE	30973902		★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	Pubtator	30973902, 36395102	Associate	★☆☆☆☆ Found in Text Mining only
Pervasive Development Disorder	Autism spectrum disorder	BEFREE	28369738, 29331800		★☆☆☆☆ Found in Text Mining only
Post-Traumatic Stress Disorder	Stress Disorder	BEFREE	22143634		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Primary biliary cirrhosis	Biliary Cirrhosis	BEFREE	18709298		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	24104703	Associate	★☆☆☆☆ Found in Text Mining only
Prune Belly Syndrome	Prune belly syndrome	BEFREE	28554003		★☆☆☆☆ Found in Text Mining only
Pruritus	Pruritus	Pubtator	18709298	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Psoriasis	Psoriasis	BEFREE	30419252, 31011876, 7426426		★☆☆☆☆ Found in Text Mining only
Psychotic Disorders	Psychosis	BEFREE	15542732		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Psychotic Disorders	Psychosis	PSYGENET_DG	15542732, 16402083		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Respiratory Distress Syndrome, Adult	Respiratory Distress Syndrome	BEFREE	31272134		★☆☆☆☆ Found in Text Mining only
Respiratory Failure	Respiratory Failure	CTD_human_DG	27192616		★☆☆☆☆ Found in Text Mining only
Retinal Diseases	Retinal Diseases	BEFREE	30944099		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	BEFREE	28415063		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	LHGDN	14623376		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	BEFREE	20112002, 22925223, 23560613, 29497192, 31582737		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	PSYGENET_DG	20112002, 22925223, 23560613		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	Pubtator	28548579	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA 12	Schizophrenia	PSYGENET_DG	22925223		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Seasonal Affective Disorder	Seasonal Affective Disorder	BEFREE	29576267		★☆☆☆☆ Found in Text Mining only
Seizures	Seizures	Pubtator	30085428	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Separation Anxiety Disorder	Separation Anxiety Disorder	BEFREE	29576267		★☆☆☆☆ Found in Text Mining only
Single Seizure	Seizure	CTD_human_DG	1675896, 18042875		★☆☆☆☆ Found in Text Mining only
Situs Inversus	Situs Inversus	BEFREE	19164126		★☆☆☆☆ Found in Text Mining only
Sleep Apnea, Obstructive	Sleep Apnea	BEFREE	30166422		★☆☆☆☆ Found in Text Mining only
Small Lymphocytic Lymphoma	Lymphocytic Leukemia	GWASCAT_DG	24292274, 28165464		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	8996236		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	22752309, 27373278		★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	32900505	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	28054321		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	31773688	Associate	★☆☆☆☆ Found in Text Mining only
SVEINSSON CHORIORETINAL ATROPHY	Sveinsson Chorioretinal Atrophy	BEFREE	25809606		★☆☆☆☆ Found in Text Mining only
T-Cell Lymphoma	T-Cell Lymphoma	BEFREE	20107485		★☆☆☆☆ Found in Text Mining only
Tonic - clonic seizures	Seizure	CTD_human_DG	1675896, 18042875		★☆☆☆☆ Found in Text Mining only
Tourette Syndrome	Tourette syndrome	Pubtator	36674940	Associate	★☆☆☆☆ Found in Text Mining only
Unipolar Depression	Mental Depression	BEFREE	20194481, 23658070, 24766998, 29331800		★☆☆☆☆ Found in Text Mining only
Urticaria	Urticaria	BEFREE	27400929		★☆☆☆☆ Found in Text Mining only
Varicosity	Vulval varices	BEFREE	29025923		★☆☆☆☆ Found in Text Mining only
Visual seizure	Seizure	CTD_human_DG	1675896, 18042875		★☆☆☆☆ Found in Text Mining only
Vitiligo	Vitiligo	BEFREE	28476568		★☆☆☆☆ Found in Text Mining only
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)	Vitiligo-associated SYSTEMIC LUPUS ERYTHEMATOSUS	BEFREE	28476568		★☆☆☆☆ Found in Text Mining only