Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	4923
Gene name	Neurotensin receptor 1
Gene symbol	NTSR1
Synonyms (NCBI Gene)	NTR
Chromosome	20
Chromosome location	20q13.33
Summary	Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secre

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017517	hsa-miR-335-5p	Microarray	18185580
MIRT029363	hsa-miR-26b-5p	Microarray	19088304
MIRT1196327	hsa-miR-1231	CLIP-seq
MIRT1196328	hsa-miR-1254	CLIP-seq
MIRT1196329	hsa-miR-1275	CLIP-seq
MIRT1196330	hsa-miR-1293	CLIP-seq
MIRT1196331	hsa-miR-1305	CLIP-seq
MIRT1196332	hsa-miR-148a	CLIP-seq
MIRT1196333	hsa-miR-148b	CLIP-seq
MIRT1196334	hsa-miR-149	CLIP-seq
MIRT1196335	hsa-miR-152	CLIP-seq
MIRT1196336	hsa-miR-1825	CLIP-seq
MIRT1196337	hsa-miR-193a-5p	CLIP-seq
MIRT1196338	hsa-miR-199a-5p	CLIP-seq
MIRT1196339	hsa-miR-199b-5p	CLIP-seq
MIRT1196340	hsa-miR-3064-5p	CLIP-seq
MIRT1196341	hsa-miR-3116	CLIP-seq
MIRT1196342	hsa-miR-3120-5p	CLIP-seq
MIRT1196343	hsa-miR-3126-5p	CLIP-seq
MIRT1196344	hsa-miR-3156-5p	CLIP-seq
MIRT1196345	hsa-miR-3176	CLIP-seq
MIRT1196346	hsa-miR-3612	CLIP-seq
MIRT1196347	hsa-miR-3622b-5p	CLIP-seq
MIRT1196348	hsa-miR-3650	CLIP-seq
MIRT1196349	hsa-miR-3677-3p	CLIP-seq
MIRT1196350	hsa-miR-3921	CLIP-seq
MIRT1196351	hsa-miR-3922-3p	CLIP-seq
MIRT1196352	hsa-miR-3925-3p	CLIP-seq
MIRT1196353	hsa-miR-4253	CLIP-seq
MIRT1196354	hsa-miR-4286	CLIP-seq
MIRT1196355	hsa-miR-432	CLIP-seq
MIRT1196356	hsa-miR-4421	CLIP-seq
MIRT1196357	hsa-miR-4440	CLIP-seq
MIRT1196358	hsa-miR-4443	CLIP-seq
MIRT1196359	hsa-miR-4455	CLIP-seq
MIRT1196360	hsa-miR-4466	CLIP-seq
MIRT1196361	hsa-miR-4483	CLIP-seq
MIRT1196362	hsa-miR-4525	CLIP-seq
MIRT1196363	hsa-miR-4653-5p	CLIP-seq
MIRT1196364	hsa-miR-4665-5p	CLIP-seq
MIRT1196365	hsa-miR-4682	CLIP-seq
MIRT1196366	hsa-miR-4699-5p	CLIP-seq
MIRT1196367	hsa-miR-4711-3p	CLIP-seq
MIRT1196368	hsa-miR-4717-5p	CLIP-seq
MIRT1196369	hsa-miR-4723-5p	CLIP-seq
MIRT1196370	hsa-miR-4757-5p	CLIP-seq
MIRT1196371	hsa-miR-4794	CLIP-seq
MIRT1196372	hsa-miR-508-5p	CLIP-seq
MIRT1196373	hsa-miR-541	CLIP-seq
MIRT1196374	hsa-miR-609	CLIP-seq
MIRT1196375	hsa-miR-625	CLIP-seq
MIRT1196376	hsa-miR-637	CLIP-seq
MIRT1196377	hsa-miR-650	CLIP-seq
MIRT1196378	hsa-miR-654-5p	CLIP-seq
MIRT1196379	hsa-miR-675	CLIP-seq
MIRT1196380	hsa-miR-760	CLIP-seq
MIRT1196331	hsa-miR-1305	CLIP-seq
MIRT2056962	hsa-miR-2110	CLIP-seq
MIRT1196340	hsa-miR-3064-5p	CLIP-seq
MIRT2056963	hsa-miR-3144-5p	CLIP-seq
MIRT2056964	hsa-miR-3150a-3p	CLIP-seq
MIRT2056965	hsa-miR-3151	CLIP-seq
MIRT2056966	hsa-miR-3175	CLIP-seq
MIRT2056967	hsa-miR-3191	CLIP-seq
MIRT2056968	hsa-miR-3199	CLIP-seq
MIRT1196346	hsa-miR-3612	CLIP-seq
MIRT2056969	hsa-miR-3919	CLIP-seq
MIRT2056970	hsa-miR-4259	CLIP-seq
MIRT1196355	hsa-miR-432	CLIP-seq
MIRT1196358	hsa-miR-4443	CLIP-seq
MIRT2056971	hsa-miR-4651	CLIP-seq
MIRT2056972	hsa-miR-4652-5p	CLIP-seq
MIRT2056973	hsa-miR-4704-3p	CLIP-seq
MIRT2056974	hsa-miR-4747-3p	CLIP-seq
MIRT2056975	hsa-miR-491-5p	CLIP-seq
MIRT2056976	hsa-miR-561	CLIP-seq
MIRT2056977	hsa-miR-571	CLIP-seq
MIRT2056978	hsa-miR-608	CLIP-seq
MIRT1196377	hsa-miR-650	CLIP-seq
MIRT2056979	hsa-miR-665	CLIP-seq
MIRT2056980	hsa-miR-939	CLIP-seq
MIRT1196327	hsa-miR-1231	CLIP-seq
MIRT2285393	hsa-miR-146b-3p	CLIP-seq
MIRT1196334	hsa-miR-149	CLIP-seq
MIRT2285394	hsa-miR-1915	CLIP-seq
MIRT2056962	hsa-miR-2110	CLIP-seq
MIRT1196340	hsa-miR-3064-5p	CLIP-seq
MIRT1196342	hsa-miR-3120-5p	CLIP-seq
MIRT2056963	hsa-miR-3144-5p	CLIP-seq
MIRT2056964	hsa-miR-3150a-3p	CLIP-seq
MIRT2056965	hsa-miR-3151	CLIP-seq
MIRT2285395	hsa-miR-3173-5p	CLIP-seq
MIRT2056966	hsa-miR-3175	CLIP-seq
MIRT2056967	hsa-miR-3191	CLIP-seq
MIRT2285396	hsa-miR-339-5p	CLIP-seq
MIRT2285397	hsa-miR-342-5p	CLIP-seq
MIRT2285398	hsa-miR-3652	CLIP-seq
MIRT2056969	hsa-miR-3919	CLIP-seq
MIRT1196350	hsa-miR-3921	CLIP-seq
MIRT2056970	hsa-miR-4259	CLIP-seq
MIRT2285399	hsa-miR-4265	CLIP-seq
MIRT2285400	hsa-miR-4281	CLIP-seq
MIRT2285401	hsa-miR-4296	CLIP-seq
MIRT2285402	hsa-miR-4322	CLIP-seq
MIRT1196356	hsa-miR-4421	CLIP-seq
MIRT2285403	hsa-miR-4430	CLIP-seq
MIRT2285404	hsa-miR-4447	CLIP-seq
MIRT2285405	hsa-miR-4449	CLIP-seq
MIRT2285406	hsa-miR-4472	CLIP-seq
MIRT2056971	hsa-miR-4651	CLIP-seq
MIRT2056972	hsa-miR-4652-5p	CLIP-seq
MIRT1196363	hsa-miR-4653-5p	CLIP-seq
MIRT2285407	hsa-miR-4664-5p	CLIP-seq
MIRT1196365	hsa-miR-4682	CLIP-seq
MIRT2285408	hsa-miR-4685-5p	CLIP-seq
MIRT2285409	hsa-miR-4691-3p	CLIP-seq
MIRT1196371	hsa-miR-4794	CLIP-seq
MIRT2056975	hsa-miR-491-5p	CLIP-seq
MIRT2056977	hsa-miR-571	CLIP-seq
MIRT2285410	hsa-miR-596	CLIP-seq
MIRT2056978	hsa-miR-608	CLIP-seq
MIRT1196380	hsa-miR-760	CLIP-seq
MIRT2285411	hsa-miR-874	CLIP-seq
MIRT2056980	hsa-miR-939	CLIP-seq
MIRT1196331	hsa-miR-1305	CLIP-seq
MIRT2056962	hsa-miR-2110	CLIP-seq
MIRT2056963	hsa-miR-3144-5p	CLIP-seq
MIRT2056964	hsa-miR-3150a-3p	CLIP-seq
MIRT2056966	hsa-miR-3175	CLIP-seq
MIRT2056967	hsa-miR-3191	CLIP-seq
MIRT1196346	hsa-miR-3612	CLIP-seq
MIRT2056970	hsa-miR-4259	CLIP-seq
MIRT1196355	hsa-miR-432	CLIP-seq
MIRT1196358	hsa-miR-4443	CLIP-seq
MIRT2056971	hsa-miR-4651	CLIP-seq
MIRT2056972	hsa-miR-4652-5p	CLIP-seq
MIRT2056975	hsa-miR-491-5p	CLIP-seq
MIRT2056977	hsa-miR-571	CLIP-seq
MIRT2056978	hsa-miR-608	CLIP-seq
MIRT1196377	hsa-miR-650	CLIP-seq
MIRT2056980	hsa-miR-939	CLIP-seq
MIRT1196332	hsa-miR-148a	CLIP-seq
MIRT1196333	hsa-miR-148b	CLIP-seq
MIRT1196335	hsa-miR-152	CLIP-seq
MIRT1196336	hsa-miR-1825	CLIP-seq
MIRT1196338	hsa-miR-199a-5p	CLIP-seq
MIRT1196339	hsa-miR-199b-5p	CLIP-seq
MIRT2583502	hsa-miR-24	CLIP-seq
MIRT2583503	hsa-miR-2467-5p	CLIP-seq
MIRT2583504	hsa-miR-3136-3p	CLIP-seq
MIRT1196345	hsa-miR-3176	CLIP-seq
MIRT1196351	hsa-miR-3922-3p	CLIP-seq
MIRT1196352	hsa-miR-3925-3p	CLIP-seq
MIRT2583505	hsa-miR-4494	CLIP-seq
MIRT1196370	hsa-miR-4757-5p	CLIP-seq
MIRT2583506	hsa-miR-499a-5p	CLIP-seq
MIRT1196372	hsa-miR-508-5p	CLIP-seq
MIRT1196332	hsa-miR-148a	CLIP-seq
MIRT1196333	hsa-miR-148b	CLIP-seq
MIRT1196335	hsa-miR-152	CLIP-seq
MIRT1196336	hsa-miR-1825	CLIP-seq
MIRT1196338	hsa-miR-199a-5p	CLIP-seq
MIRT1196339	hsa-miR-199b-5p	CLIP-seq
MIRT2583502	hsa-miR-24	CLIP-seq
MIRT2583503	hsa-miR-2467-5p	CLIP-seq
MIRT2583504	hsa-miR-3136-3p	CLIP-seq
MIRT1196345	hsa-miR-3176	CLIP-seq
MIRT1196351	hsa-miR-3922-3p	CLIP-seq
MIRT1196352	hsa-miR-3925-3p	CLIP-seq
MIRT2583505	hsa-miR-4494	CLIP-seq
MIRT1196370	hsa-miR-4757-5p	CLIP-seq
MIRT2583506	hsa-miR-499a-5p	CLIP-seq
MIRT1196372	hsa-miR-508-5p	CLIP-seq

Show/Hide all (68)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001659	Process	Temperature homeostasis	IEA
GO:0003085	Process	Negative regulation of systemic arterial blood pressure	IEA
GO:0003254	Process	Regulation of membrane depolarization	IEA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	TAS	8381365
GO:0005515	Function	Protein binding	IPI	17620610, 23597562
GO:0005783	Component	Endoplasmic reticulum	TAS	9763490
GO:0005794	Component	Golgi apparatus	TAS	9763490
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	IMP	8381365
GO:0005886	Component	Plasma membrane	TAS	8381365
GO:0006171	Process	CAMP biosynthetic process	IEA
GO:0006950	Process	Response to stress	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS	8381365
GO:0007218	Process	Neuropeptide signaling pathway	IBA
GO:0007218	Process	Neuropeptide signaling pathway	IDA	21725197
GO:0007218	Process	Neuropeptide signaling pathway	IGI	21806946
GO:0007268	Process	Chemical synaptic transmission	TAS	9763490
GO:0007612	Process	Learning	IEA
GO:0008306	Process	Associative learning	IEA
GO:0008344	Process	Adult locomotory behavior	IEA
GO:0009898	Component	Cytoplasmic side of plasma membrane	IEA
GO:0009986	Component	Cell surface	IEA
GO:0010628	Process	Positive regulation of gene expression	IGI	21806946
GO:0014049	Process	Positive regulation of glutamate secretion	IEA
GO:0014054	Process	Positive regulation of gamma-aminobutyric acid secretion	IEA
GO:0016020	Component	Membrane	IEA
GO:0016492	Function	G protein-coupled neurotensin receptor activity	IBA
GO:0016492	Function	G protein-coupled neurotensin receptor activity	IDA	21725197
GO:0016492	Function	G protein-coupled neurotensin receptor activity	IEA
GO:0016492	Function	G protein-coupled neurotensin receptor activity	IMP	8381365
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IEA
GO:0032094	Process	Response to food	IEA
GO:0032280	Component	Symmetric synapse	IEA
GO:0032960	Process	Regulation of inositol trisphosphate biosynthetic process	IEA
GO:0033993	Process	Response to lipid	IEA
GO:0040017	Process	Positive regulation of locomotion	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	17620610
GO:0043025	Component	Neuronal cell body	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	21725197
GO:0043195	Component	Terminal bouton	IEA
GO:0043197	Component	Dendritic spine	IEA
GO:0043198	Component	Dendritic shaft	IEA
GO:0043204	Component	Perikaryon	IEA
GO:0043576	Process	Regulation of respiratory gaseous exchange	IEA
GO:0043679	Component	Axon terminus	IEA
GO:0044309	Component	Neuron spine	IEA
GO:0044877	Function	Protein-containing complex binding	IEA
GO:0045121	Component	Membrane raft	IDA	21725197
GO:0045121	Component	Membrane raft	IEA
GO:0050965	Process	Detection of temperature stimulus involved in sensory perception of pain	IEA
GO:0051280	Process	Negative regulation of release of sequestered calcium ion into cytosol	IEA
GO:0051281	Process	Positive regulation of release of sequestered calcium ion into cytosol	IEA
GO:0060732	Process	Positive regulation of inositol phosphate biosynthetic process	IEA
GO:0070779	Process	D-aspartate import across plasma membrane	IEA
GO:0071545	Process	Inositol phosphate catabolic process	IEA
GO:0071625	Process	Vocalization behavior	IEA
GO:0090238	Process	Positive regulation of arachidonate secretion	IEA
GO:0097151	Process	Positive regulation of inhibitory postsynaptic potential	IEA
GO:0098712	Process	L-glutamate import across plasma membrane	IEA
GO:1990708	Process	Conditioned place preference	IEA
GO:2000822	Process	Regulation of behavioral fear response	IEA

MIM	HGNC	e!Ensembl
162651	8039	ENSG00000101188

P30989

Protein name

Neurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH)

Protein function

G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:21725197, PubMed:23140271, PubMed:8381365). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to

PDB

2LYW , 6OS9 , 6OSA , 6PWC , 6UP7 , 7UL2 , 8JPB , 8JPC , 8JPF

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00001	7tm_1	80 → 364	7 transmembrane receptor (rhodopsin family)	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain. {ECO:0000269|PubMed:20048080, ECO:0000269|PubMed:8381365}.

Sequence

MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY

Sequence length

418

Interactions

View interactions

	KEGG		Reactome
	Calcium signaling pathway Neuroactive ligand-receptor interaction		Peptide ligand-binding receptors G alpha (q) signalling events

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (10)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MOOD DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (116)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma	Adenocarcinoma	BEFREE	18541341, 20810387, 28836043		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	LHGDN	18541341		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of colon	Adenocarcinoma Of Colon	BEFREE	18541341		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	20810387, 25249545		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of pancreas	Pancreatic adenocarcinoma	BEFREE	29025990		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenoma	Adenoma	BEFREE	21630261		★★★★★ ★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	11927634, 22142809	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Alzheimer Disease	Alzheimer disease	Pubtator	16539663, 21397006	Inhibit	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	31013092		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anophthalmia with pulmonary hypoplasia	Anophthalmia	Pubtator	36949141	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Anorexia	Anorexia	BEFREE	29241540		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis, Psoriatic	Psoriatic Arthritis	BEFREE	30613279		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorders	Autism Spectrum Disorder	CTD_human_DG	24781735		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Benign Prostatic Hyperplasia	Benign Prostatic Hyperplasia	BEFREE	30959962, 31264168		★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain neoplasms	Pubtator	30959962	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	21573500, 21725197, 25031704, 25249538		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	11359788, 19156213, 21725197, 22161836, 27388253	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	26298774	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoid Tumor	Carcinoid tumor	Pubtator	26298774	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	10690540		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ductal	Ductal carcinoma	Pubtator	16258511	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	27611941	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	17018595, 20810387, 25249545		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	29025990	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	28790113, 30883751		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebral Hemorrhage	Cerebral hemorrhage	Pubtator	21672317	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognition disorder	Pubtator	21397006	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cognitive Dysfunction	Cognition disorder	Pubtator	16539663	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	21630261, 27076683		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	Pubtator	23901225	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	18541341, 21630261, 28254866, 31158752, 9706144		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	9092553	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	20663927, 26334593, 28498396		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	16984735, 20663927, 26334593, 32764278	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	BEFREE	26334593, 30554192		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	28498396	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms Hereditary Nonpolyposis	Lynch syndrome	Pubtator	34680073	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Depressive Disorder Major	Major depressive disorder	Pubtator	26278479	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatitis, Atopic	Dermatitis	BEFREE	24033157		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	18285558		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	18285558		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ectodermal Dysplasia Anhidrotic with Immunodeficiency Osteopetrosis and Lymphedema	Anhidrotic ectodermal dysplasia with immunodeficiency, osteopetrosis, and lymphedema	Pubtator	9454839	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Eczema	Eczema	BEFREE	24033157		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial adenocarcinoma	Endometrial Adenocarcinoma	BEFREE	28836043		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	28836043		★★★★★ ★☆☆☆☆ Found in Text Mining only
Essential Tremor	Essential tremor	Pubtator	26297037	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Fulminant hepatitis	Fulminant Hepatitis	BEFREE	12077097, 19040539		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	BEFREE	21364741		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	25200966, 26180082, 28494471, 29065410, 30261490		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	25200966, 26180082, 28494471, 29065410, 30261490		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	23576602, 31028138	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	25644759, 30261490		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hemorrhage	Hemorrhage	Pubtator	21672317	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hepatitis C	Hepatitis c	Pubtator	16500930	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington disease	Pubtator	18093249	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypothyroidism	Hypothyroidism	Pubtator	32597152	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypothyroidism	Hypothyroidism	Pubtator	34104248	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	19393580	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	21212273		★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	21212273	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	23901225	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Keratoconus	Keratoconus	Pubtator	16275928	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	27914862, 29900041		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	LHGDN	17018595		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	25249545		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	27388253	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma, T-Cell, Cutaneous	Lymphoma	LHGDN	14962098		★★★★★ ★☆☆☆☆ Found in Text Mining only
Major Depressive Disorder	Mental Depression	BEFREE	21621269, 24081561, 27002284		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Fibrous Histiocytoma	Malignant Histiocytoma	BEFREE	31478563		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Glioma	Glioma	BEFREE	25644759		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	21573500, 21725197, 25031704, 25249538		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of endometrium	Endometrial Cancer	BEFREE	28836043		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	17018595, 20810387, 25249545		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	28790113, 30883751		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	10690540, 26471393, 28536844, 29889537		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	17409433, 20018219, 21748756, 28849698, 30770901, 30959962, 31034212, 31264168		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	25724188, 29794962		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	10690540, 21630261, 21753794, 25249538, 25644759, 27424910, 27911447, 28790113, 29025990, 29189173, 29794962		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	18541341, 21630261, 31158752, 9706144		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	25249538, 28690201		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mesothelioma	Mesothelioma	BEFREE	19932148		★★★★★ ★☆☆☆☆ Found in Text Mining only
Migraine Disorders	Migraine	BEFREE	24081561		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mild cognitive disorder	Cognitive disorder	BEFREE	16539663, 17908035		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mood Disorders	Mood Disorder	BEFREE	17357149		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mood Disorders	Mood Disorder	PSYGENET_DG	22754041		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neoplasms	Neoplasms	BEFREE	10690540, 11888915, 17409433, 18541341, 20592307, 21364741, 21605619, 21630261, 22914496, 25031704, 25249545, 25644759, 26334593, 26471393, 27911447 View all (13 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	10336437, 11927634	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroendocrine Tumors	Neuroendocrine Tumors	BEFREE	26298774, 29272741		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	20810387, 31614143		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	28834751		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	28790113, 30883751		★★★★★ ★☆☆☆☆ Found in Text Mining only
PACHYONYCHIA CONGENITA 3	Pachyonychia Congenita	BEFREE	31034212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	10690540, 26471393, 28536844, 29889537		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Diseases	Pancreatic Diseases	BEFREE	10690540		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Ductal Adenocarcinoma	Pancreatic adenocarcinoma	BEFREE	28536844, 31013092		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasm	Pancreatic Neoplasm	BEFREE	29889537		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	10816627, 19393580, 29025990	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatitis	Pancreatitis	BEFREE	28536844		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatitis, Chronic	Pancreatitis	BEFREE	10690540		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	17409433, 20018219, 21748756, 28849698, 30770901, 30959962, 31034212, 31264168		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	BEFREE	11398197		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	LHGDN	17289170		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	21097678	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	28849698, 30959962	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	BEFREE	22283733		★★★★★ ★☆☆☆☆ Found in Text Mining only
Psychotic Disorders	Psychotic disorders	Pubtator	25027171	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	11032391, 23483448		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	CTD_human_DG	20659557		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Squamous cell carcinoma	Carcinoma	BEFREE	18661521, 21605619		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	18661521, 29904026		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	25724188, 29794962		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	25724188, 26215716, 29794962, 34839352	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Thyroiditis Autoimmune	Thyroiditis	Pubtator	32597152, 34104248	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple Negative Breast Neoplasms	BEFREE	29790803		★★★★★ ★☆☆☆☆ Found in Text Mining only
Unipolar Depression	Mental Depression	BEFREE	21621269		★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Fibroids	Uterine Fibroids	BEFREE	20592307		★★★★★ ★☆☆☆☆ Found in Text Mining only

NTSR1 (neurotensin receptor 1)