Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID	4863
Gene name	Nuclear protein, coactivator of histone transcription
Gene symbol	NPAT
Synonyms (NCBI Gene)	E14E14/NPATp220
Chromosome	11
Chromosome location	11q22.3

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Show/Hide all (311)

miRTarBase ID	miRNA	Experiments	Reference
MIRT000261	hsa-miR-17-5p	Luciferase reporter assay	19734348
MIRT440099	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT472058	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT472057	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT472056	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT472055	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT000261	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT440101	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT472054	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT472052	hsa-miR-3609	PAR-CLIP	23592263
MIRT472053	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT472051	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT472050	hsa-miR-595	PAR-CLIP	23592263
MIRT472049	hsa-miR-4797-5p	PAR-CLIP	23592263
MIRT472048	hsa-miR-4773	PAR-CLIP	23592263
MIRT472047	hsa-miR-3925-5p	PAR-CLIP	23592263
MIRT472046	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT472045	hsa-miR-1245a	PAR-CLIP	23592263
MIRT472044	hsa-miR-8079	PAR-CLIP	23592263
MIRT472043	hsa-miR-759	PAR-CLIP	23592263
MIRT472042	hsa-miR-4765	PAR-CLIP	23592263
MIRT472041	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT472040	hsa-miR-4772-5p	PAR-CLIP	23592263
MIRT472039	hsa-miR-520a-5p	PAR-CLIP	23592263
MIRT472038	hsa-miR-525-5p	PAR-CLIP	23592263
MIRT472037	hsa-miR-3180-5p	PAR-CLIP	23592263
MIRT440101	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440099	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440101	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT000261	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT472055	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT472057	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT472056	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440099	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440099	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT472058	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT472057	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT472056	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT472055	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT000261	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT440101	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT472054	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT472052	hsa-miR-3609	PAR-CLIP	23592263
MIRT472053	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT472051	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT472050	hsa-miR-595	PAR-CLIP	23592263
MIRT472049	hsa-miR-4797-5p	PAR-CLIP	23592263
MIRT472048	hsa-miR-4773	PAR-CLIP	23592263
MIRT472047	hsa-miR-3925-5p	PAR-CLIP	23592263
MIRT472046	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT472045	hsa-miR-1245a	PAR-CLIP	23592263
MIRT472044	hsa-miR-8079	PAR-CLIP	23592263
MIRT472043	hsa-miR-759	PAR-CLIP	23592263
MIRT472042	hsa-miR-4765	PAR-CLIP	23592263
MIRT472041	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT472040	hsa-miR-4772-5p	PAR-CLIP	23592263
MIRT472039	hsa-miR-520a-5p	PAR-CLIP	23592263
MIRT472038	hsa-miR-525-5p	PAR-CLIP	23592263
MIRT472037	hsa-miR-3180-5p	PAR-CLIP	23592263
MIRT1190419	hsa-miR-106a	CLIP-seq
MIRT1190420	hsa-miR-106b	CLIP-seq
MIRT1190421	hsa-miR-124	CLIP-seq
MIRT1190422	hsa-miR-1264	CLIP-seq
MIRT1190423	hsa-miR-1276	CLIP-seq
MIRT1190424	hsa-miR-1283	CLIP-seq
MIRT1190425	hsa-miR-130a	CLIP-seq
MIRT1190426	hsa-miR-130b	CLIP-seq
MIRT1190427	hsa-miR-135a	CLIP-seq
MIRT1190428	hsa-miR-135b	CLIP-seq
MIRT1190429	hsa-miR-142-5p	CLIP-seq
MIRT1190430	hsa-miR-17	CLIP-seq
MIRT1190431	hsa-miR-191	CLIP-seq
MIRT1190432	hsa-miR-200b	CLIP-seq
MIRT1190433	hsa-miR-200c	CLIP-seq
MIRT1190434	hsa-miR-20a	CLIP-seq
MIRT1190435	hsa-miR-20b	CLIP-seq
MIRT1190436	hsa-miR-24	CLIP-seq
MIRT1190437	hsa-miR-301a	CLIP-seq
MIRT1190438	hsa-miR-301b	CLIP-seq
MIRT1190439	hsa-miR-3120-3p	CLIP-seq
MIRT1190440	hsa-miR-3145-3p	CLIP-seq
MIRT1190441	hsa-miR-3160-5p	CLIP-seq
MIRT1190442	hsa-miR-3168	CLIP-seq
MIRT1190443	hsa-miR-3183	CLIP-seq
MIRT1190444	hsa-miR-33a	CLIP-seq
MIRT1190445	hsa-miR-33b	CLIP-seq
MIRT1190446	hsa-miR-340	CLIP-seq
MIRT1190447	hsa-miR-3607-3p	CLIP-seq
MIRT1190448	hsa-miR-3622a-5p	CLIP-seq
MIRT1190449	hsa-miR-3646	CLIP-seq
MIRT1190450	hsa-miR-3665	CLIP-seq
MIRT1190451	hsa-miR-3666	CLIP-seq
MIRT1190452	hsa-miR-3686	CLIP-seq
MIRT1190453	hsa-miR-369-3p	CLIP-seq
MIRT1190454	hsa-miR-374a	CLIP-seq
MIRT1190455	hsa-miR-374b	CLIP-seq
MIRT1190456	hsa-miR-374c	CLIP-seq
MIRT1190457	hsa-miR-3919	CLIP-seq
MIRT1190458	hsa-miR-3942-3p	CLIP-seq
MIRT1190459	hsa-miR-4282	CLIP-seq
MIRT1190460	hsa-miR-4284	CLIP-seq
MIRT1190461	hsa-miR-429	CLIP-seq
MIRT1190462	hsa-miR-4295	CLIP-seq
MIRT1190463	hsa-miR-4311	CLIP-seq
MIRT1190464	hsa-miR-4423-3p	CLIP-seq
MIRT1190465	hsa-miR-4473	CLIP-seq
MIRT1190466	hsa-miR-4475	CLIP-seq
MIRT1190467	hsa-miR-4477b	CLIP-seq
MIRT1190468	hsa-miR-4495	CLIP-seq
MIRT1190469	hsa-miR-454	CLIP-seq
MIRT1190470	hsa-miR-4670-3p	CLIP-seq
MIRT1190471	hsa-miR-4671-3p	CLIP-seq
MIRT1190472	hsa-miR-4699-3p	CLIP-seq
MIRT1190473	hsa-miR-4723-3p	CLIP-seq
MIRT1190474	hsa-miR-4744	CLIP-seq
MIRT1190475	hsa-miR-4753-3p	CLIP-seq
MIRT1190476	hsa-miR-4760-5p	CLIP-seq
MIRT1190477	hsa-miR-4768-5p	CLIP-seq
MIRT1190478	hsa-miR-506	CLIP-seq
MIRT1190479	hsa-miR-519a	CLIP-seq
MIRT1190480	hsa-miR-519b-3p	CLIP-seq
MIRT1190481	hsa-miR-519c-3p	CLIP-seq
MIRT1190482	hsa-miR-519d	CLIP-seq
MIRT1190483	hsa-miR-520d-5p	CLIP-seq
MIRT1190484	hsa-miR-524-5p	CLIP-seq
MIRT1190485	hsa-miR-548ah	CLIP-seq
MIRT1190486	hsa-miR-548c-3p	CLIP-seq
MIRT1190487	hsa-miR-548k	CLIP-seq
MIRT1190488	hsa-miR-561	CLIP-seq
MIRT1190489	hsa-miR-583	CLIP-seq
MIRT1190490	hsa-miR-590-3p	CLIP-seq
MIRT1190491	hsa-miR-600	CLIP-seq
MIRT1190492	hsa-miR-627	CLIP-seq
MIRT1190493	hsa-miR-645	CLIP-seq
MIRT1190494	hsa-miR-655	CLIP-seq
MIRT1190495	hsa-miR-657	CLIP-seq
MIRT1190496	hsa-miR-887	CLIP-seq
MIRT1190497	hsa-miR-889	CLIP-seq
MIRT1190498	hsa-miR-924	CLIP-seq
MIRT1190499	hsa-miR-93	CLIP-seq
MIRT1190419	hsa-miR-106a	CLIP-seq
MIRT1190420	hsa-miR-106b	CLIP-seq
MIRT2055131	hsa-miR-1284	CLIP-seq
MIRT1190430	hsa-miR-17	CLIP-seq
MIRT1190434	hsa-miR-20a	CLIP-seq
MIRT1190435	hsa-miR-20b	CLIP-seq
MIRT2055132	hsa-miR-219-2-3p	CLIP-seq
MIRT2055133	hsa-miR-330-3p	CLIP-seq
MIRT2055134	hsa-miR-338-5p	CLIP-seq
MIRT2055135	hsa-miR-3688-3p	CLIP-seq
MIRT2055136	hsa-miR-4328	CLIP-seq
MIRT2055137	hsa-miR-450b-5p	CLIP-seq
MIRT2055138	hsa-miR-507	CLIP-seq
MIRT1190482	hsa-miR-519d	CLIP-seq
MIRT1190485	hsa-miR-548ah	CLIP-seq
MIRT2055139	hsa-miR-557	CLIP-seq
MIRT2055140	hsa-miR-582-5p	CLIP-seq
MIRT1190499	hsa-miR-93	CLIP-seq
MIRT1190419	hsa-miR-106a	CLIP-seq
MIRT1190420	hsa-miR-106b	CLIP-seq
MIRT2284081	hsa-miR-1245	CLIP-seq
MIRT2284082	hsa-miR-129-5p	CLIP-seq
MIRT1190427	hsa-miR-135a	CLIP-seq
MIRT1190428	hsa-miR-135b	CLIP-seq
MIRT1190429	hsa-miR-142-5p	CLIP-seq
MIRT2284083	hsa-miR-144	CLIP-seq
MIRT1190430	hsa-miR-17	CLIP-seq
MIRT1190434	hsa-miR-20a	CLIP-seq
MIRT1190435	hsa-miR-20b	CLIP-seq
MIRT2284084	hsa-miR-2355-5p	CLIP-seq
MIRT1190436	hsa-miR-24	CLIP-seq
MIRT2284085	hsa-miR-3065-5p	CLIP-seq
MIRT1190439	hsa-miR-3120-3p	CLIP-seq
MIRT2284086	hsa-miR-3148	CLIP-seq
MIRT1190441	hsa-miR-3160-5p	CLIP-seq
MIRT2284087	hsa-miR-338-3p	CLIP-seq
MIRT2055134	hsa-miR-338-5p	CLIP-seq
MIRT1190446	hsa-miR-340	CLIP-seq
MIRT1190448	hsa-miR-3622a-5p	CLIP-seq
MIRT1190450	hsa-miR-3665	CLIP-seq
MIRT2055135	hsa-miR-3688-3p	CLIP-seq
MIRT2284088	hsa-miR-383	CLIP-seq
MIRT2284089	hsa-miR-3936	CLIP-seq
MIRT2284090	hsa-miR-3941	CLIP-seq
MIRT1190458	hsa-miR-3942-3p	CLIP-seq
MIRT1190459	hsa-miR-4282	CLIP-seq
MIRT1190460	hsa-miR-4284	CLIP-seq
MIRT2284091	hsa-miR-4310	CLIP-seq
MIRT1190463	hsa-miR-4311	CLIP-seq
MIRT1190464	hsa-miR-4423-3p	CLIP-seq
MIRT2284092	hsa-miR-4457	CLIP-seq
MIRT2284093	hsa-miR-4496	CLIP-seq
MIRT2055137	hsa-miR-450b-5p	CLIP-seq
MIRT2284094	hsa-miR-4639-3p	CLIP-seq
MIRT2284095	hsa-miR-466	CLIP-seq
MIRT2284096	hsa-miR-4668-5p	CLIP-seq
MIRT1190470	hsa-miR-4670-3p	CLIP-seq
MIRT2284097	hsa-miR-4672	CLIP-seq
MIRT2284098	hsa-miR-4691-5p	CLIP-seq
MIRT1190472	hsa-miR-4699-3p	CLIP-seq
MIRT1190476	hsa-miR-4760-5p	CLIP-seq
MIRT2284099	hsa-miR-4778-5p	CLIP-seq
MIRT2284100	hsa-miR-4795-3p	CLIP-seq
MIRT2284101	hsa-miR-499-3p	CLIP-seq
MIRT2284102	hsa-miR-499a-3p	CLIP-seq
MIRT2284103	hsa-miR-500a	CLIP-seq
MIRT2055138	hsa-miR-507	CLIP-seq
MIRT2284104	hsa-miR-513a-3p	CLIP-seq
MIRT2284105	hsa-miR-513b	CLIP-seq
MIRT1190479	hsa-miR-519a	CLIP-seq
MIRT1190480	hsa-miR-519b-3p	CLIP-seq
MIRT1190481	hsa-miR-519c-3p	CLIP-seq
MIRT1190482	hsa-miR-519d	CLIP-seq
MIRT2284106	hsa-miR-548ae	CLIP-seq
MIRT1190485	hsa-miR-548ah	CLIP-seq
MIRT2284107	hsa-miR-548aj	CLIP-seq
MIRT2284108	hsa-miR-548am	CLIP-seq
MIRT1190487	hsa-miR-548k	CLIP-seq
MIRT2284109	hsa-miR-548n	CLIP-seq
MIRT2284110	hsa-miR-548t	CLIP-seq
MIRT2284111	hsa-miR-548x	CLIP-seq
MIRT2055139	hsa-miR-557	CLIP-seq
MIRT1190488	hsa-miR-561	CLIP-seq
MIRT1190490	hsa-miR-590-3p	CLIP-seq
MIRT1190491	hsa-miR-600	CLIP-seq
MIRT2284112	hsa-miR-605	CLIP-seq
MIRT1190493	hsa-miR-645	CLIP-seq
MIRT1190495	hsa-miR-657	CLIP-seq
MIRT2284113	hsa-miR-876-3p	CLIP-seq
MIRT1190497	hsa-miR-889	CLIP-seq
MIRT1190499	hsa-miR-93	CLIP-seq
MIRT1190419	hsa-miR-106a	CLIP-seq
MIRT1190420	hsa-miR-106b	CLIP-seq
MIRT1190429	hsa-miR-142-5p	CLIP-seq
MIRT1190430	hsa-miR-17	CLIP-seq
MIRT1190434	hsa-miR-20a	CLIP-seq
MIRT1190435	hsa-miR-20b	CLIP-seq
MIRT1190441	hsa-miR-3160-5p	CLIP-seq
MIRT2391684	hsa-miR-3162-3p	CLIP-seq
MIRT1190446	hsa-miR-340	CLIP-seq
MIRT2391685	hsa-miR-3938	CLIP-seq
MIRT1190458	hsa-miR-3942-3p	CLIP-seq
MIRT2055136	hsa-miR-4328	CLIP-seq
MIRT1190470	hsa-miR-4670-3p	CLIP-seq
MIRT2391686	hsa-miR-4733-5p	CLIP-seq
MIRT1190476	hsa-miR-4760-5p	CLIP-seq
MIRT2284099	hsa-miR-4778-5p	CLIP-seq
MIRT1190479	hsa-miR-519a	CLIP-seq
MIRT1190480	hsa-miR-519b-3p	CLIP-seq
MIRT1190481	hsa-miR-519c-3p	CLIP-seq
MIRT1190482	hsa-miR-519d	CLIP-seq
MIRT1190485	hsa-miR-548ah	CLIP-seq
MIRT1190499	hsa-miR-93	CLIP-seq
MIRT2455348	hsa-miR-141	CLIP-seq
MIRT2455349	hsa-miR-194	CLIP-seq
MIRT2455350	hsa-miR-200a	CLIP-seq
MIRT1190466	hsa-miR-4475	CLIP-seq
MIRT1190467	hsa-miR-4477b	CLIP-seq
MIRT2055131	hsa-miR-1284	CLIP-seq
MIRT2455348	hsa-miR-141	CLIP-seq
MIRT2284083	hsa-miR-144	CLIP-seq
MIRT2455349	hsa-miR-194	CLIP-seq
MIRT2455350	hsa-miR-200a	CLIP-seq
MIRT2055132	hsa-miR-219-2-3p	CLIP-seq
MIRT2582194	hsa-miR-2276	CLIP-seq
MIRT2582195	hsa-miR-3119	CLIP-seq
MIRT2055133	hsa-miR-330-3p	CLIP-seq
MIRT2055134	hsa-miR-338-5p	CLIP-seq
MIRT2582196	hsa-miR-3678-3p	CLIP-seq
MIRT2055135	hsa-miR-3688-3p	CLIP-seq
MIRT2284090	hsa-miR-3941	CLIP-seq
MIRT2055136	hsa-miR-4328	CLIP-seq
MIRT2582197	hsa-miR-4446-5p	CLIP-seq
MIRT1190466	hsa-miR-4475	CLIP-seq
MIRT1190467	hsa-miR-4477b	CLIP-seq
MIRT2055137	hsa-miR-450b-5p	CLIP-seq
MIRT2284095	hsa-miR-466	CLIP-seq
MIRT2284097	hsa-miR-4672	CLIP-seq
MIRT1190472	hsa-miR-4699-3p	CLIP-seq
MIRT2582198	hsa-miR-4772-3p	CLIP-seq
MIRT2055138	hsa-miR-507	CLIP-seq
MIRT2582199	hsa-miR-544	CLIP-seq
MIRT2055139	hsa-miR-557	CLIP-seq
MIRT2055140	hsa-miR-582-5p	CLIP-seq
MIRT2055131	hsa-miR-1284	CLIP-seq
MIRT2455348	hsa-miR-141	CLIP-seq
MIRT2284083	hsa-miR-144	CLIP-seq
MIRT2455349	hsa-miR-194	CLIP-seq
MIRT2455350	hsa-miR-200a	CLIP-seq
MIRT2055132	hsa-miR-219-2-3p	CLIP-seq
MIRT2582194	hsa-miR-2276	CLIP-seq
MIRT2582195	hsa-miR-3119	CLIP-seq
MIRT2055133	hsa-miR-330-3p	CLIP-seq
MIRT2055134	hsa-miR-338-5p	CLIP-seq
MIRT2582196	hsa-miR-3678-3p	CLIP-seq
MIRT2055135	hsa-miR-3688-3p	CLIP-seq
MIRT2284090	hsa-miR-3941	CLIP-seq
MIRT2055136	hsa-miR-4328	CLIP-seq
MIRT2582197	hsa-miR-4446-5p	CLIP-seq
MIRT1190466	hsa-miR-4475	CLIP-seq
MIRT1190467	hsa-miR-4477b	CLIP-seq
MIRT2055137	hsa-miR-450b-5p	CLIP-seq
MIRT2284095	hsa-miR-466	CLIP-seq
MIRT2284097	hsa-miR-4672	CLIP-seq
MIRT1190472	hsa-miR-4699-3p	CLIP-seq
MIRT2582198	hsa-miR-4772-3p	CLIP-seq
MIRT2055138	hsa-miR-507	CLIP-seq
MIRT2582199	hsa-miR-544	CLIP-seq
MIRT1190486	hsa-miR-548c-3p	CLIP-seq
MIRT2055139	hsa-miR-557	CLIP-seq
MIRT2055140	hsa-miR-582-5p	CLIP-seq

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Transcription factor	Regulation	Reference
E2F1	Activation	12665581

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001701	Process	In utero embryonic development	IEA
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0003713	Function	Transcription coactivator activity	IDA	14585971, 17974976
GO:0003713	Function	Transcription coactivator activity	IMP	15988025, 17163457
GO:0003714	Function	Transcription corepressor activity	IMP	17163457
GO:0005515	Function	Protein binding	IPI	15988025, 18850719, 19170105
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	15988025, 19170105
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA	17068332
GO:0005737	Component	Cytoplasm	IDA	17068332
GO:0015030	Component	Cajal body	IDA	15988025, 17068332, 17577209, 19170105
GO:0015030	Component	Cajal body	IEA
GO:0044843	Process	Cell cycle G1/S phase transition	IMP	15988025
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	18850719
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	18850719
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	15988025
GO:0097504	Component	Gemini of Cajal bodies	IDA	17068332

MIM	HGNC	e!Ensembl
601448	7896	ENSG00000149308

Q14207

Protein name

Protein NPAT (Nuclear protein of the ataxia telangiectasia mutated locus) (Nuclear protein of the ATM locus) (p220)

Protein function

Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, M

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15712	NPAT_C	758 → 1427	NPAT C terminus	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:8743993, ECO:0000269|PubMed:8923007}.

Sequence

MLLPSDVARLVLGYLQQENLISTCQTFILESSDLKEYAEHCTDEGFIPACLLSLFGKNLT
TILNEYVAMKTKETSNNVPAIMSSLWKKLDHTLSQIRSMQSSPRFAGSQRARTRTGIAEI
KRQRKLASQTAPASAELLTLPYLSGQFTTPPSTGTQVTRPSGQISDPSRSYFVVVNHSQS
QDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRKSTTLSGPHSTIRNFQDPNAFAV
EKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSIDEFLG
LPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQPMESNPSIVL
ADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQIS
TSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETE
MAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSL
TGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSC
LQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQ
EPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNT
DDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSP
TKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVT
PCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQ
PLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNN
FSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGC
HAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPN
HKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTT
IRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSEKS
IASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLA
DSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPAS
ETGSENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERER
NSRPSSKNLTNSSIPMKKKKIKKKKLPSSFPAGMDVDKFLLSLHYDE

Sequence length

1427

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (10)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLEAR CELL RENAL CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLONAL HEMATOPOIESIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GenCC	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FAMILIAL COLORECTAL CANCER TYPE X	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Uncertain significance; Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NPAT-related disorder	Likely benign; Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (16)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adult Hodgkin Lymphoma	Hodgkin Lymphoma	BEFREE	21562039		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ataxia Telangiectasia	Ataxia Telangiectasia	BEFREE	23977206, 8743993, 9060412, 9205109		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ataxia Telangiectasia	Ataxia telangiectasia	Pubtator	23977206, 8743993	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
B-CELL MALIGNANCY, LOW-GRADE	Lymphocytic Leukemia	BEFREE	17449237		★★★★★ ★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	21050672		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	21050672		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	17449237		★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Failure	Heart failure	Pubtator	12601168	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin Disease	BEFREE	21562039		★★★★★ ★☆☆☆☆ Found in Text Mining only
Language Disorders	Language Disorders	BEFREE	23977206		★★★★★ ★☆☆☆☆ Found in Text Mining only
Language Disorders	Language development disorders	Pubtator	23977206	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	21050672		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	20053773, 9205109		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nodular Lymphocyte Predominant Hodgkin Lymphoma	Classical Hodgkin lymphoma	BEFREE	21562039		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	20053773	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	19277982	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

NPAT (nuclear protein, coactivator of histone transcription)